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  1. Article ; Online: Memory advantage for untrustworthy faces: Replication across lab- and web-based studies.

    Giraudier, Manon / Ventura-Bort, Carlos / Wendt, Julia / Lischke, Alexander / Weymar, Mathias

    PloS one

    2022  Volume 17, Issue 2, Page(s) e0264034

    Abstract: The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing ... ...

    Abstract The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research.
    MeSH term(s) Adult ; COVID-19/epidemiology ; COVID-19/psychology ; COVID-19/virology ; Facial Expression ; Female ; Germany/epidemiology ; Humans ; Internet/statistics & numerical data ; Male ; Memory, Episodic ; Mental Recall/physiology ; Recognition, Psychology ; SARS-CoV-2/isolation & purification ; Trust ; Young Adult
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0264034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Transcutaneous Vagus Nerve Stimulation (tVNS) Improves High-Confidence Recognition Memory but Not Emotional Word Processing.

    Giraudier, Manon / Ventura-Bort, Carlos / Weymar, Mathias

    Frontiers in psychology

    2020  Volume 11, Page(s) 1276

    Abstract: Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive ... ...

    Abstract Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes.
    Language English
    Publishing date 2020-07-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2020.01276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Memory advantage for untrustworthy faces

    Manon Giraudier / Carlos Ventura-Bort / Julia Wendt / Alexander Lischke / Mathias Weymar

    PLoS ONE, Vol 17, Iss 2, p e

    Replication across lab- and web-based studies.

    2022  Volume 0264034

    Abstract: The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing ... ...

    Abstract The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Memory advantage for untrustworthy faces

    Manon Giraudier / Carlos Ventura-Bort / Julia Wendt / Alexander Lischke / Mathias Weymar

    PLoS ONE, Vol 17, Iss

    Replication across lab- and web-based studies

    2022  Volume 2

    Abstract: The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing ... ...

    Abstract The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants’ memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Transcutaneous vagus nerve stimulation (tVNS) improves high-confidence recognition memory but not emotional word processing

    Giraudier, Manon / Ventura-Bort, Carlos / Weymar, Mathias

    Frontiers in Psychology

    2020  

    Abstract: Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive ... ...

    Title translation Transkutane Vagusnervstimulation (tVNS) verbessert das Wiedererkennungsgedächtnis mit hohem Vertrauen, aber nicht die emotionale Wortverarbeitung
    Abstract Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes.
    Keywords Emotionen ; Emotions ; Episodic Memory ; Episodisches Gedächtnis ; Familiarity ; Gedächtniskonsolidierung ; Human Information Storage ; Informationsspeicherprozesse beim Menschen ; Lexical Decision ; Lexikalische Entscheidung ; Memory Consolidation ; Nerve Stimulation ; Nervenstimulation ; Recognition (Learning) ; Saliva ; Speichel ; Textverarbeitung ; Vagus Nerve ; Vagusnerv ; Vertrautheit ; Wiedererkennen (Lernen) ; Word Processing
    Language English
    Document type Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2020.01276
    Database PSYNDEX

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  6. Article ; Online: Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis.

    Giraudier, Manon / Ventura-Bort, Carlos / Burger, Andreas M / Claes, Nathalie / D'Agostini, Martina / Fischer, Rico / Franssen, Mathijs / Kaess, Michael / Koenig, Julian / Liepelt, Roman / Nieuwenhuis, Sander / Sommer, Aldo / Usichenko, Taras / Van Diest, Ilse / von Leupoldt, Andreas / Warren, Christopher M / Weymar, Mathias

    Brain stimulation

    2022  Volume 15, Issue 6, Page(s) 1378–1388

    Abstract: Background: Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus coeruleus- ...

    Abstract Background: Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus coeruleus-noradrenaline (LC-NA) system. Reliable effects of taVNS on markers of LC-NA system activity, however, have not been demonstrated yet.
    Methods: The aim of the present study was to overcome previous limitations by pooling raw data from a large sample of ten taVNS studies (371 healthy participants) that collected salivary alpha-amylase (sAA) as a potential marker of central NA release.
    Results: While a meta-analytic approach using summary statistics did not yield any significant effects, linear mixed model analyses showed that afferent stimulation of the vagus nerve via taVNS increased sAA levels compared to sham stimulation (b = 0.16, SE = 0.05, p = 0.001). When considering potential confounders of sAA, we further replicated previous findings on the diurnal trajectory of sAA activity.
    Conclusion(s): Vagal activation via taVNS increases sAA release compared to sham stimulation, which likely substantiates the assumption that taVNS triggers NA release. Moreover, our results highlight the benefits of data pooling and data sharing in order to allow stronger conclusions in research.
    Language English
    Publishing date 2022-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2394410-9
    ISSN 1876-4754 ; 1935-861X
    ISSN (online) 1876-4754
    ISSN 1935-861X
    DOI 10.1016/j.brs.2022.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker

    Giraudier, Manon / Ventura-Bort, Carlos / Burger, Andreas M. / Claes, Nathalie / D'Agostini, Martina / Fischer, Rico / Franssen, Mathijs / Kaess, Michael / Koenig, Julian / Liepelt, Roman / Nieuwenhuis, Sander / Sommer, Aldo / Usichenko, Taras / Van Diest, Ilse / von Leupoldt, Andreas / Warren, Christopher M. / Weymar, Mathias

    Brain Stimulation

    A pooled mega-analysis

    2022  Volume 15, Issue 6, Page(s) 1378–1388

    Abstract: Abstract not released by publisher. ...

    Title translation Belege für eine modulierende Wirkung der transkutanen aurikulären Vagusnervstimulation (taVNS) auf die Speichel-Alpha-Amylase als indirekten noradrenergen Marker: Eine gepoolte Mega-Analyse. (DeepL)
    Abstract Abstract not released by publisher.
    Keywords Biological Markers ; Biologische Marker ; Locus Caeruleus ; Locus Ceruleus ; Nerve Stimulation ; Nervenstimulation ; Neuromodulation ; Nichtinvasive Hirnstimulation ; Noninvasive Brain Stimulation ; Noradrenalin ; Norepinephrine ; Vagus Nerve ; Vagusnerv
    Language English
    Document type Article
    ZDB-ID 2394410-9
    ISSN 1935-861X
    ISSN 1935-861X
    DOI 10.1016/j.brs.2022.09.009
    Database PSYNDEX

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