Article ; Online: Drug-resistant epicrania fugax: Responding to onabotulinumtoxinA.
2023 Volume 63, Issue 6, Page(s) 839–842
Abstract: Epicrania fugax (EF) is a primary headache consisting of brief paroxysms of pain, lasting 1-10 s, that move through different nerve territories of one hemicranium with a linear or zigzag trajectory, although there are some clinical variants. Preventive ... ...
| Abstract | Epicrania fugax (EF) is a primary headache consisting of brief paroxysms of pain, lasting 1-10 s, that move through different nerve territories of one hemicranium with a linear or zigzag trajectory, although there are some clinical variants. Preventive therapy with anti-seizure medication such as gabapentin and lamotrigine are most commonly used in patients presenting with frequent and non-remitting attacks. In some cases, greater occipital nerve blockades are used for short- or long-term relief. Here, we report two patients with a paroxysmal EF-type pain who meet the criteria for EF of the International Classification of Headache Disorders, 3rd edition, with clear triggers and autonomic ocular signs and who failed multiple preventive treatments, but had a sustained response to onabotulinumtoxinA. |
|---|---|
| MeSH term(s) | Humans ; Botulinum Toxins, Type A/pharmacology ; Botulinum Toxins, Type A/therapeutic use ; Headache/diagnosis ; Pain ; Headache Disorders ; Gabapentin |
| Chemical Substances | Botulinum Toxins, Type A (EC 3.4.24.69) ; Gabapentin (6CW7F3G59X) |
| Language | English |
| Publishing date | 2023-06-20 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 410130-3 |
| ISSN | 1526-4610 ; 0017-8748 |
| ISSN (online) | 1526-4610 |
| ISSN | 0017-8748 |
| DOI | 10.1111/head.14532 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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