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  1. Article ; Online: Promising Efforts to Define a Novel Approach to Neuroprotection for Acute Ischemic Stroke.

    Anderson, Craig S / Song, Lili

    JAMA neurology

    2024  

    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2023.5727
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.191: Show issues Location:
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  2. Article ; Online: Trials in intracerebral haemorrhage: a path to success?

    Song, Lili / Chen, Xiaoying

    The Lancet. Neurology

    2023  Volume 22, Issue 7, Page(s) 542–543

    MeSH term(s) Humans ; Cerebral Hemorrhage/therapy
    Language English
    Publishing date 2023-06-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2081241-3
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(23)00201-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5955: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Micturition-Induced Reflex Epilepsy.

    Li, Xia / Wang, Rui / Song, Wenchun / Xie, Lili

    Neurology India

    2024  Volume 71, Issue 6, Page(s) 1309–1310

    MeSH term(s) Humans ; Urination ; Epilepsy, Reflex/etiology ; Reflex
    Language English
    Publishing date 2024-01-04
    Publishing country India
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.391379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 698: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Huperzine alkaloids: forty years of total syntheses.

    Cheng, Bichu / Song, Lili / Chen, Fener

    Natural product reports

    2024  Volume 41, Issue 1, Page(s) 59–84

    Abstract: Covering: up to 2023Huperzine alkaloids are a group of natural products belonging to ... ...

    Abstract Covering: up to 2023Huperzine alkaloids are a group of natural products belonging to the
    MeSH term(s) Molecular Structure ; Lycopodium/chemistry ; Alkaloids/chemistry ; Sesquiterpenes/chemistry
    Chemical Substances huperzine A (0111871I23) ; Alkaloids ; Sesquiterpenes
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d3np00029j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Idiopathic gingival fibromatosis and primary analysis of dominant bacteria in subgingival biofilm: a case report.

    Zhu, Jingli / Fan, Xinyue / Ding, Lili / Song, Tianzhu

    The Journal of international medical research

    2024  Volume 52, Issue 4, Page(s) 3000605241245302

    Abstract: Idiopathic gingival fibromatosis (IGF), a rare fibroproliferative disease of unknown etiology, affects gingival tissue and has substantial adverse effects on patients. Therefore, the pathogenesis of IGF requires more extensive and in-depth research. In ... ...

    Abstract Idiopathic gingival fibromatosis (IGF), a rare fibroproliferative disease of unknown etiology, affects gingival tissue and has substantial adverse effects on patients. Therefore, the pathogenesis of IGF requires more extensive and in-depth research. In this case, a patient with confirmed IGF underwent initial nonsurgical periodontal therapy and gingivectomy, and the prognosis was good. The patient had no loss of periodontal attachment but had a history of swelling and bleeding of the gingiva prior to fibrous enlargement, which prompted further investigation. We explored the patient's subgingival microbiome and found a high abundance of periodontal pathogens. Gingival tissue biopsy revealed abundant fibrous tissue containing multiple inflammatory cell infiltrates. These results suggest that gingival inflammation secondary to periodontal pathogens can contribute to IGF onset.
    MeSH term(s) Humans ; Biofilms/growth & development ; Fibromatosis, Gingival/diagnosis ; Fibromatosis, Gingival/pathology ; Fibromatosis, Gingival/microbiology ; Gingiva/microbiology ; Gingiva/pathology ; Female ; Adult ; Male ; Bacteria/isolation & purification ; Gingivectomy/methods
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/03000605241245302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 925: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Anti-Aging Activity and Modes of Action of Compounds from Natural Food Sources.

    Song, Lili / Zhang, Shicui

    Biomolecules

    2023  Volume 13, Issue 11

    Abstract: Aging is a natural and inescapable phenomenon characterized by a progressive deterioration of physiological functions, leading to increased vulnerability to chronic diseases and death. With economic and medical development, the elderly population is ... ...

    Abstract Aging is a natural and inescapable phenomenon characterized by a progressive deterioration of physiological functions, leading to increased vulnerability to chronic diseases and death. With economic and medical development, the elderly population is gradually increasing, which poses a great burden to society, the economy and the medical field. Thus, healthy aging has now become a common aspiration among people over the world. Accumulating evidence indicates that substances that can mediate the deteriorated physiological processes are highly likely to have the potential to prolong lifespan and improve aging-associated diseases. Foods from natural sources are full of bioactive compounds, such as polysaccharides, polyphenols, carotenoids, sterols, terpenoids and vitamins. These bioactive compounds and their derivatives have been shown to be able to delay aging and/or improve aging-associated diseases, thereby prolonging lifespan, via regulation of various physiological processes. Here, we summarize the current understanding of the anti-aging activities of the compounds, polysaccharides, polyphenols, carotenoids, sterols, terpenoids and vitamins from natural food sources, and their modes of action in delaying aging and improving aging-associated diseases. This will certainly provide a reference for further research on the anti-aging effects of bioactive compounds from natural food sources.
    MeSH term(s) Aged ; Humans ; Aging ; Carotenoids/pharmacology ; Polyphenols/pharmacology ; Vitamins/pharmacology ; Terpenes/pharmacology ; Sterols ; Polysaccharides
    Chemical Substances Carotenoids (36-88-4) ; Polyphenols ; Vitamins ; Terpenes ; Sterols ; Polysaccharides
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13111600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A surface defect detection method for steel pipe based on improved YOLO.

    Wang, Lili / Song, Chunhe / Wan, Guangxi / Cui, Shijie

    Mathematical biosciences and engineering : MBE

    2024  Volume 21, Issue 2, Page(s) 3016–3036

    Abstract: Surface defect detection is of great significance as a tool to ensure the quality of steel pipes. The surface defects of steel pipes are charactered by insufficient texture, high similarity between different types of defects, large size differences, and ... ...

    Abstract Surface defect detection is of great significance as a tool to ensure the quality of steel pipes. The surface defects of steel pipes are charactered by insufficient texture, high similarity between different types of defects, large size differences, and high proportions of small targets, posing great challenges to defect detection algorithms. To overcome the above issues, we propose a novel steel pipe surface defect detection method based on the YOLO framework. First, for the problem of a low detection rate caused by insufficient texture and high similarity among different types of defects of steel pipes, a new backbone block is proposed. By increasing high-order spatial interaction and enhancing the capture of internal correlations of data features, different feature information for similar defects is extracted, thereby alleviating the false detection rate. Second, to enhance the detection performance for small defects, a new neck block is proposed. By fusing multiple features, the accuracy of steel pipe defect detection is improved. Third, for the problem of a low detection rate causing large size differences in steel pipe surface defects, a novel regression loss function that considers the aspect ratio and scale is proposed, and the focal loss is introduced to further solve the sample imbalance problem in steel pipe defect datasets. The experimental results show that the proposed method can effectively improve the accuracy of steel pipe surface defect detection.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2024134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Optimizing the Structure and Optical Properties of Lanthanum Aluminate Perovskite through Nb

    Liu, Wei / Zou, Yang / Chen, Yuang / Lei, Zijian / Zhao, Lili / Song, Lixin

    Nanomaterials (Basel, Switzerland)

    2024  Volume 14, Issue 7

    Abstract: This work involves the introduction of niobium oxide into lanthanum aluminate ( ... ...

    Abstract This work involves the introduction of niobium oxide into lanthanum aluminate (LaAlO
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14070608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: MicroRNA-195-5p Attenuates Pregnancy-Induced Hypertension by Inhibiting Oxidative Stress via OTX1/MAPK Signaling Pathway.

    Liu, Lili / Yao, Chunfeng / Song, Zhihui

    Biochemical genetics

    2024  

    Abstract: Pregnancy-induced hypertension (PIH) is a hypertensive disorder during pregnancy and can induce perinatal death of human infants. MicroRNA (miR)-195-5p was validated to display low expression in severe preeclampsia placentas, but the role of miR-195-5p ... ...

    Abstract Pregnancy-induced hypertension (PIH) is a hypertensive disorder during pregnancy and can induce perinatal death of human infants. MicroRNA (miR)-195-5p was validated to display low expression in severe preeclampsia placentas, but the role of miR-195-5p in pregnancy-induced hypertension (PIH) has not been investigated. The study emphasized on the functions and mechanism of miR-195-5p in PIH. A reduced uterine perfusion pressure (RUPP) rat model was established to mimic PIH in vivo. Adenovirus (Ad)-miR-195-5p agomir and/or Ad-OTX1 were further injected into some model rats. RT-qPCR was conducted to assess the expression of miR-195-5p and orthodenticle homeobox 1 (OTX1) in rat placental tissues, the isolated aortic endothelial cells (AECs), and in serum samples of PIH patients. Western blot analysis was implemented to measure the protein levels of OTX1, VEGFA, and key factors involved in the MAPK signaling pathway. The concentrations of oxidative stress markers (superoxide dismutase, catalase, and lipid hydroperoxide) in AECs and placental tissues of RUPP rats were measured by corresponding kits. The binding relation between miR-195-5p and OTX1 was verified using the dual-luciferase reporter assay. Hematoxylin-eosin staining was conducted to evaluate the pathological features of rat placental tissues. MiR-195-5p was downregulated, while OTX1 was upregulated in rat placental tissues and human serum samples of PIH patients. MiR-195-5p could target OTX1 and inversely regulate OTX1 expression in AECs and rat placental tissues. In addition, miR-195-5p can negatively regulate VEGFA level. Furthermore, miR-195-5p inactivates oxidative stress and the MAPK signaling by downregulating OTX1 in AECs. In vivo experiments revealed that OTX1 overexpression reversed the protective effect of miR-195-5p overexpression on placental damage and oxidative stress. MiR-195-5p alleviates PIH by inhibiting oxidative stress via targeting OTX1 and inactivating MAPK signaling.
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2168-4
    ISSN 1573-4927 ; 0006-2928
    ISSN (online) 1573-4927
    ISSN 0006-2928
    DOI 10.1007/s10528-023-10612-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Expression and role of FKBPL in lung adenocarcinoma.

    She, Lili / Zhang, Xingsong / Shen, Rong / He, Song / Miao, Xiaobing

    Journal of Cancer

    2024  Volume 15, Issue 1, Page(s) 166–175

    Abstract: Dysregulated expression of FK506-binding protein like (FKBPL) has been demonstrated to play crucial roles in tumour development. However, the role of FKBPL in lung adenocarcinoma (ADC) remains unclear. Using immunohistochemical staining, we showed that ... ...

    Abstract Dysregulated expression of FK506-binding protein like (FKBPL) has been demonstrated to play crucial roles in tumour development. However, the role of FKBPL in lung adenocarcinoma (ADC) remains unclear. Using immunohistochemical staining, we showed that FKBPL expression was significantly lower in lung ADC than the normal tissues (
    Language English
    Publishing date 2024-01-01
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.87758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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