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  1. Article ; Online: Letter to the Editor:

    Koh, Samuel Ji Quan / Sim, David Kheng Leng / Neo, Shirlyn Hui-Shan

    Journal of palliative medicine

    2023  Volume 26, Issue 7, Page(s) 893–895

    MeSH term(s) Humans ; Artificial Intelligence ; Heart Failure/therapy
    Language English
    Publishing date 2023-07-10
    Publishing country United States
    Document type Letter
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2023.0199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5440: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Extramammary Paget's disease: Our 15-year experience in a Southeast Asian population.

    Wong, Allen Wei-Jiat / Sim, Nadia Hui Shan / Ooi, Adrian

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 84, Page(s) 392–397

    Abstract: The treatment of choice for Extramammary Paget's disease (EMPD) is wide excision. However, owing to the tendency of microscopic spread and multi-centricity of the disease, resection margins are hard to determine. Despite the use of adjunctive methods ... ...

    Abstract The treatment of choice for Extramammary Paget's disease (EMPD) is wide excision. However, owing to the tendency of microscopic spread and multi-centricity of the disease, resection margins are hard to determine. Despite the use of adjunctive methods such as mapping biopsy and Moh's micrographic surgery, recurrence rates remain high. We aim to establish treatment guidelines by determining the variables associated with recurrence and the optimal resection margin size. We reviewed 52 patients who underwent wide excision in our institution between 2002 and 2017. A retrospective review of patient demographics, disease characteristics, and resection margins was performed. Most patients were Chinese (n = 39, 75%) male (n = 38, 73.1%). The mean tumor size was 6.73 cm (SD=4.10; range, 1.50-21.0 cm). The mean resection margin was 2.5 cm (SD=1.21; range, 0.20-5.50 cm). Eleven patients (21.2%) had disease recurrence. Nodal involvement significantly correlated with disease recurrence or mortality related to disease (HR=4.645; 95% CI=1.539,14.018; p = 0.0064). Subgroup analysis showed a significant correlation between resection margin size and recurrence rates (p = 0.047). We observed that a smaller resection margin (<2 cm) is acceptable for smaller tumor sizes (<6 cm) to achieve the lowest possible recurrence rates (20%), whereas a larger resection margin (>2 cm) is required for larger tumor sizes (>6 cm) (p = 0.012). Our results suggest that a resection margin recommendation can be made in correlation to the tumor size. This serves as a guideline for surgeons to predict the defect size and provide options for reconstructive surgery while achieving low recurrence rates.
    MeSH term(s) Female ; Humans ; Male ; Biopsy ; Margins of Excision ; Paget Disease, Extramammary/ethnology ; Paget Disease, Extramammary/pathology ; Paget Disease, Extramammary/surgery ; Retrospective Studies ; Singapore ; Asia, Southeastern
    Language English
    Publishing date 2023-06-09
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.06.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.157: Show issues Location:
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  3. Article ; Online: Elements of Potentially Inappropriate Interventions and Patient Prognostic Profiles at the End of Life in Cardiology: A Qualitative Analysis.

    Lo, Jamie J / Yoon, Sungwon / Neo, Shirlyn Hui Shan / Sim, David Kheng Leng / Graves, Nicholas

    Journal of palliative medicine

    2023  Volume 26, Issue 5, Page(s) 700–703

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Prognosis ; Cardiology ; Death ; Singapore
    Language English
    Publishing date 2023-02-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2022.0564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5440: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article: Mental health and psychosocial support during healthcare emergencies - COVID-19 pandemic.

    Sim, Hui Shan / How, Choon How

    Singapore medical journal

    2020  Volume 61, Issue 7, Page(s) 357–362

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/psychology ; Emergencies ; Humans ; Mental Health ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/psychology ; SARS-CoV-2 ; Social Support
    Keywords covid19
    Language English
    Publishing date 2020-07-29
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 604319-7
    ISSN 0037-5675
    ISSN 0037-5675
    DOI 10.11622/smedj.2020103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 589: Show issues Location:
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  6. Article ; Online: Preferred Neighborhood Projects Among Millennials

    Hui-Shan Sim / Weng-Wai Choong / Siaw-Chui Wee / Sheau-Ting Low

    International Journal of Built Environment and Sustainability, Vol 9, Iss 2, Pp 1-

    Yes, In My Backyard

    2022  Volume 9

    Abstract: The millennial generation, Gen Y and Gen Z, have different residential preferences compared to the previous generation. This study aims to understand the millennial’s preferences towards the type of project development and their willingness to pay for ... ...

    Abstract The millennial generation, Gen Y and Gen Z, have different residential preferences compared to the previous generation. This study aims to understand the millennial’s preferences towards the type of project development and their willingness to pay for the premium towards the preferred type of development to be built in their neighborhood. A total of 407 responses were collected through online survey and analyzed by using relative important index and frequency analysis. The results imply that millennials prefer recreational park, police booth, community garden, transit station and feeder bus route to be built within their neighborhood. Nevertheless, millennials are more willing to pay for the transit station, followed by educational institution, recreational park, police booth, and integrated public transport terminal. This study will help planners, developers, and the local authority to understand the preferences among the millennials, thus matching with relevant development to enhance liveability and better marketability of their residential project.
    Keywords preferences study ; project development ; millennials ; willingness to pay ; yimby ; Architecture ; NA1-9428 ; Human ecology. Anthropogeography ; GF1-900
    Subject code 710
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Universiti Teknologi Malaysia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Reconstruction of a massive chest wall defect using a free anterolateral-lower medial thigh flaps: a case report.

    Sim, Nadia Hui Shan / Ngaserin, Sabrina / Feng, Jia Jun / Kok, Yee Onn / Chua, Hui Wen / Gaviria-Pinzon, Jorge / Chew, Khong Yik / Wong, Allen WeiJiat

    Journal of surgical case reports

    2023  Volume 2023, Issue 5, Page(s) rjad264

    Abstract: Critical defects of the chest wall require robust soft tissue coverage to protect the thoracic viscera. We define massive chest wall defects as larger than two-thirds of the chest wall. For such defects, classic flaps like the omentum, latissimus dorsi ... ...

    Abstract Critical defects of the chest wall require robust soft tissue coverage to protect the thoracic viscera. We define massive chest wall defects as larger than two-thirds of the chest wall. For such defects, classic flaps like the omentum, latissimus dorsi and anterolateral thigh flaps are usually insufficient. In our patient, a bilateral total mastectomy for locally advanced breast cancer resulted in a massive chest wall defect (40 by 30 cm). Soft tissue coverage was achieved with a combined anterolateral-lower medial thigh flaps. Revascularization of the anterolateral thigh and lower medial thigh components was via the internal mammary and thoracoacromial vessels, respectively. Post-operative recovery was uneventful and the patient received adjuvant chemoradiotherapy in a timely manner. The total follow up was 24-months. We illustrate the novel use of the lower medial thigh territory in extending the size of the anterolateral thigh flap to reconstruct massive chest wall defects.
    Language English
    Publishing date 2023-05-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correction to: Clinical profile of children with parechovirus meningitis in Singapore.

    Tan, Jessica Hui Yin / Choong, Chew Thye / Tee, Nancy Wen Sim / Chong, Chia Yin / Thoon, Koh Cheng / Maiwald, Matthias / Lee, Elis Yue Xian / Tan, Melody Si Shan / Tan, Natalie Woon Hui

    Journal of neurovirology

    2022  Volume 28, Issue 1, Page(s) 52–53

    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1283265-0
    ISSN 1538-2443 ; 1355-0284
    ISSN (online) 1538-2443
    ISSN 1355-0284
    DOI 10.1007/s13365-022-01057-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4426: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Factors Influencing Potentially Futile Treatments at the End of Life in a Multiethnic Asian Cardiology Setting: A Qualitative Study.

    Lo, Jamie J / Yoon, Sungwon / Neo, Shirlyn Hui Shan / Sim, David Kheng Leng / Graves, Nicholas

    The American journal of hospice & palliative care

    2021  Volume 39, Issue 9, Page(s) 1005–1013

    Abstract: Background: Modern medicine enables clinicians to save lives and prolong time to death, yet some treatments have little chance of conferring meaningful benefits for patients nearing the end-of-life. What clinicians perceive as driving futile treatment ... ...

    Abstract Background: Modern medicine enables clinicians to save lives and prolong time to death, yet some treatments have little chance of conferring meaningful benefits for patients nearing the end-of-life. What clinicians perceive as driving futile treatment in the non-Western healthcare context is poorly understood.
    Aim: This study aimed to explore clinicians' perceptions of the factors that influence futile treatment at the end of life within a tertiary hospital cardiac care setting.
    Design: We conducted semi-structured interviews with cardiologists, cardiac surgeons, and palliative care doctors from a large national cardiology center in Singapore. Interviews were transcribed verbatim and thematically analyzed.
    Results: A total of 32 clinicians were interviewed. We identified factors that contributed to the provision of potentially futile treatment in these theme areas: patient- and family-related, clinician-related, and institutional and societal factors. Family roles and cultural influences were most commonly cited by participants as affecting end-of-life decisions and altering the likelihood of futile treatment. Specialty-specific alignments within cardiology and availability of healthcare resources were also important factors underpinning futile treatment.
    Conclusion: Family-related factors were a primary driver for futile treatment in a non-Western, multicultural setting. Future interventions should consider a targeted approach accounting for cultural and contextual factors to prevent and reduce futile treatment.
    MeSH term(s) Attitude of Health Personnel ; Cardiology ; Death ; Decision Making ; Humans ; Medical Futility ; Qualitative Research ; Terminal Care
    Language English
    Publishing date 2021-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074344-3
    ISSN 1938-2715 ; 1049-9091
    ISSN (online) 1938-2715
    ISSN 1049-9091
    DOI 10.1177/10499091211053624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3090: Show issues Location:
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  10. Article: Management of knee osteoarthritis in primary care.

    Sim, Hui Shan / Ang, Ke Xin Magneline / How, Choon How / Loh, Sir Young James

    Singapore medical journal

    2020  Volume 61, Issue 10, Page(s) 512–516

    MeSH term(s) Aged ; Arthralgia/complications ; Female ; Humans ; Male ; Middle Aged ; Osteoarthritis, Knee/complications ; Osteoarthritis, Knee/diagnosis ; Osteoarthritis, Knee/therapy ; Primary Health Care ; Range of Motion, Articular
    Language English
    Publishing date 2020-11-22
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604319-7
    ISSN 0037-5675
    ISSN 0037-5675
    DOI 10.11622/smedj.2020147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 589: Show issues Location:
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