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  1. Article: Mental Health and Aggression in Indonesian Women.

    Hamzy, Aryati / Chen, Cheng-Chung / Hsieh, Kuan-Ying

    Behavioral sciences (Basel, Switzerland)

    2023  Volume 13, Issue 9

    Abstract: Aggression is a global problem and complex social behavior. In Indonesia, some common manifestations of aggression are sexual harassment, domestic violence, and the stigmatization of other people. However, unlike men, aggression in women is still rarely ... ...

    Abstract Aggression is a global problem and complex social behavior. In Indonesia, some common manifestations of aggression are sexual harassment, domestic violence, and the stigmatization of other people. However, unlike men, aggression in women is still rarely studied, whereas facts find that many conditions can make women more vulnerable. There are various aspects related to biological, psychological, social, and cultural issues that can potentially provoke female aggression. Furthermore, mental health and aggression are often viewed as an automatic association and are inseparable in society, reinforcing the stigma against people with mental problems, particularly women, who tend to suffer more stigma of mental health issues than men. However, there has not yet been a study explicitly related to this relationship in the general population of women. The current study aims to examine the overall relationship between mental health and aggression in the extensive general population of Indonesian women with various mental conditions ranging from a normal mental state to severe mental health problems. This was a cross-sectional study conducted using uncontrolled quota sampling via distributing online self-report questionnaires, the modified Indonesian version instruments of the Brief Symptoms Rating Scale-5, and the Buss Aggression Scale with high internal consistency. This study among 203 women aged 19-67 in Indonesia, a multicultural nation and the fourth densest country in the world, proposes that mental health can be a predictor of aggressive behavior, with the influence of mental health on the aggression of women being 21.6% only. The finding indicates that mental health issues are not a macro contributing factor to women's aggressiveness in society and may help reduce stigma against women with mental health problems.
    Language English
    Publishing date 2023-08-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs13090727
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hyperpolarized Carbon-13 Magnetic Resonance Imaging: Technical Considerations and Clinical Applications.

    Lai, Ying-Chieh / Hsieh, Ching-Yi / Juan, Yu-Hsiang / Lu, Kuan-Ying / Lee, Hsien-Ju / Ng, Shu-Hang / Wan, Yung-Liang / Lin, Gigin

    Korean journal of radiology

    2024  Volume 25, Issue 5, Page(s) 459–472

    Abstract: Hyperpolarized (HP) carbon-13 ( ...

    Abstract Hyperpolarized (HP) carbon-13 (
    MeSH term(s) Humans ; Magnetic Resonance Imaging/methods ; Carbon Isotopes ; Male ; Muscle, Skeletal/diagnostic imaging ; Brain/diagnostic imaging ; Brain/metabolism ; Female ; Pyruvic Acid ; Liver/diagnostic imaging
    Chemical Substances Carbon Isotopes ; Carbon-13 (FDJ0A8596D) ; Pyruvic Acid (8558G7RUTR)
    Language English
    Publishing date 2024-04-29
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2046981-0
    ISSN 2005-8330 ; 1229-6929
    ISSN (online) 2005-8330
    ISSN 1229-6929
    DOI 10.3348/kjr.2024.0069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Understanding the mental health impacts of biological disasters: Lessons from Taiwan's experience with COVID-19.

    Chang, Chih-Chieh / Hsieh, Kuan-Ying / Hsu, Su-Ting / Wang, Yu-Yuan / Chou, Frank Huang-Chih / Huang, Joh-Jong

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2024  

    Abstract: Biological disasters pose a growing challenge in the 21st century, significantly impacting global society. Taiwan has experienced such disasters, resulting in long-term consequences like loss of life, trauma, economic decline, and societal disruptions. ... ...

    Abstract Biological disasters pose a growing challenge in the 21st century, significantly impacting global society. Taiwan has experienced such disasters, resulting in long-term consequences like loss of life, trauma, economic decline, and societal disruptions. Post-disaster, mental health issues such as fear, anxiety, depression, post-traumatic stress disorder (PTSD), and stress surge, accompanied by increased suicide rates. The Coronavirus disease 2019 (COVID-19) (also called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) pandemic, recognized as a biological disaster, triggered lockdowns and quarantines in Taiwan, causing lifestyle changes, economic recession, and so on. These shifts may elevate uncertainty about the future, intensifying mental stress and leading to a rise in various mental illnesses. This article reviews mental health studies conducted in Taiwan during the pandemic, emphasizing the need to integrate this research for future preparedness and interventions regarding the mental health impacts of biological disasters, including COVID-19. Further research is essential to explore long-term effects, interventions, and generalizability.
    Language English
    Publishing date 2024-03-22
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2024.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hyperpolarized [1-

    Lin, Gigin / Hsieh, Ching-Yi / Lai, Ying-Chieh / Wang, Chun-Chieh / Lin, Yenpo / Lu, Kuan-Ying / Chai, Wen-Yen / Chen, Albert P / Yen, Tzu-Chen / Ng, Shu-Hang / Lai, Chyong-Huey

    European radiology experimental

    2024  Volume 8, Issue 1, Page(s) 46

    Abstract: Background: Monitoring pyruvate metabolism in the spleen is important for assessing immune activity and achieving successful radiotherapy for cervical cancer due to the significance of the abscopal effect. We aimed to explore the feasibility of ... ...

    Abstract Background: Monitoring pyruvate metabolism in the spleen is important for assessing immune activity and achieving successful radiotherapy for cervical cancer due to the significance of the abscopal effect. We aimed to explore the feasibility of utilizing hyperpolarized (HP) [1-
    Methods: This prospective study recruited six female patients with cervical cancer (median age 55 years; range 39-60) evaluated using HP [1-
    Results: The splenic HP [1-
    Conclusions: This exploratory study revealed the feasibility of HP [1-
    Trial registration: ClinicalTrials.gov NCT04951921 , registered 7 July 2021.
    Relevance statement: This prospective study revealed the feasibility of using HP
    Key points: • Effective radiotherapy induces abscopal effect via altering immune metabolism. • Hyperpolarized
    MeSH term(s) Humans ; Female ; Middle Aged ; Pyruvic Acid/metabolism ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/radiotherapy ; Prospective Studies ; Carbon-13 Magnetic Resonance Spectroscopy/methods ; Lactates
    Chemical Substances Pyruvic Acid (8558G7RUTR) ; Lactates
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ISSN 2509-9280
    ISSN (online) 2509-9280
    DOI 10.1186/s41747-024-00445-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Impact of Psychological Burdens and Vaccine Worries on Confidence and Adherence to Governmental Policies Against COVID-19 Among Patients with Substance Use Disorder: A Cross-Sectional Study in Taiwan.

    Li, Dian-Jeng / Huang, Joh-Jong / Hsu, Su-Ting / Wu, Hui-Ching / Hsieh, Kuan-Ying / Lin, Guei-Ging / Wu, Pei-Jhen / Liu, Chin-Lien / Chou, Frank Huang-Chih

    Neuropsychiatric disease and treatment

    2024  Volume 20, Page(s) 597–606

    Abstract: Introduction: The coronavirus disease 2019 (COVID-19) pandemic has had an impact on patients with substance use disorder (SUD). We aimed to investigate factors associated with confidence and adherence to governmental policies against COVID-19 (social ... ...

    Abstract Introduction: The coronavirus disease 2019 (COVID-19) pandemic has had an impact on patients with substance use disorder (SUD). We aimed to investigate factors associated with confidence and adherence to governmental policies against COVID-19 (social desirability) among patients with SUD.
    Methods: This cross-sectional study was conducted during 2020 to 2021. Patients with SUD and healthy controls were recruited. The severity of sleep disturbance, social desirability, drug dependence, vaccine worries, other psychological burdens and demographic variables were collected through self-administrated questionnaires. Differences between the SUD and control groups were estimated. Hierarchical regression analysis was used to identify significant relationships between social desirability and other factors.
    Results: In total, 58 of patients with SUD and 47 healthy controls were recruited. The patients with SUD had a lower level of social desirability and more severe sleep disturbance than the control group. Older age, more severe sleep disturbance, lower level of drug dependence, and lower level of vaccine worries were significantly associated with a higher level of social desirability among the patients with SUD.
    Conclusion: Our results show the importance of timely interventions for drug dependence and to address vaccine worries in patients with SUD.
    Language English
    Publishing date 2024-03-12
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186503-6
    ISSN 1178-2021 ; 1176-6328
    ISSN (online) 1178-2021
    ISSN 1176-6328
    DOI 10.2147/NDT.S453238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Developing a Method to Estimate the Downstream Metabolite Signals from Hyperpolarized [1-

    Hsieh, Ching-Yi / Sung, Cheng-Hsuan / Shen, Yi-Liang Eric / Lai, Ying-Chieh / Lu, Kuan-Ying / Lin, Gigin

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 15

    Abstract: Hyperpolarized carbon-13 MRI has the advantage of allowing the study of glycolytic flow in vivo or in vitro dynamically in real-time. The apparent exchange rate constant of a metabolite dynamic signal reflects the metabolite changes of a disease. ... ...

    Abstract Hyperpolarized carbon-13 MRI has the advantage of allowing the study of glycolytic flow in vivo or in vitro dynamically in real-time. The apparent exchange rate constant of a metabolite dynamic signal reflects the metabolite changes of a disease. Downstream metabolites can have a low signal-to-noise ratio (SNR), causing apparent exchange rate constant inconsistencies. Thus, we developed a method that estimates a more accurate metabolite signal. This method utilizes a kinetic model and background noise to estimate metabolite signals. Simulations and in vitro studies with photon-irradiated and control groups were used to evaluate the procedure. Simulated and in vitro exchange rate constants estimated using our method were compared with the raw signal values. In vitro data were also compared to the Area-Under-Curve (AUC) of the cell medium in
    MeSH term(s) Humans ; Kinetics ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy/methods ; Pyruvic Acid ; Signal-To-Noise Ratio
    Chemical Substances Pyruvic Acid (8558G7RUTR)
    Language English
    Publishing date 2022-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22155480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comparison of Elixhauser and Charlson Methods for Discriminative Performance in Mortality Risk in Patients with Schizophrenic Disorders.

    Tsai, Kuan-Yi / Hsieh, Kuan-Ying / Ou, Shu-Yu / Chou, Frank Huang-Chih / Chou, Yu-Mei

    International journal of environmental research and public health

    2020  Volume 17, Issue 7

    Abstract: Although Charlson Comorbidity Index scores (CCIS) and Elixhauser comorbidity index scores (ECIS) have been used to assess comorbidity in patients with schizophrenia, only CCIS, not ECIS, have been used to predict mortality in this population. This ... ...

    Abstract Although Charlson Comorbidity Index scores (CCIS) and Elixhauser comorbidity index scores (ECIS) have been used to assess comorbidity in patients with schizophrenia, only CCIS, not ECIS, have been used to predict mortality in this population. This nationwide retrospective study investigated discriminative performance of mortality of these two scales in patients with schizophrenia. Exploiting Taiwan's National Health Insurance Research Database (NHRID), we identified patients diagnosed with schizophrenia discharged from hospitals between Jan 1, 1996 and Dec 31, 2007. They were followed up for subsequent death. Comorbidities presented one year prior to hospital admissions were identified and adapted to the CCIS and ECIS. Discriminatory ability was evaluated using the adjusted hazard ratio and Akaike information criterion (AIC) and Harrell's C-statistic. We identified 58,771 discharged patients with schizophrenic disorders and followed them for a mean of 10.4 years, 16.6% of whom had died. Both ECIS and CCIS were significantly associated with mortality, but ECIS had superior discriminatory ability by a lower AIC and higher Harrell's C-statistic (201231 vs. 201400; 0.856 vs. 0.854, respectively). ECIS had better discriminative performance in mortality risk than CCIS in patients with schizophrenic disorders. Its use may be encouraged for risk adjustment in this population.
    MeSH term(s) Adult ; Comorbidity ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Retrospective Studies ; Risk Assessment ; Schizophrenia/mortality ; Taiwan/epidemiology
    Language English
    Publishing date 2020-04-03
    Publishing country Switzerland
    Document type Journal Article
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17072450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Comparing Magnetic Resonance Fingerprinting (MRF) and the MAGiC Sequence for Simultaneous T1 and T2 Quantitative Measurements in the Female Pelvis: A Prospective Study.

    Huang, Bo-Syuan / Hsieh, Ching-Yi / Chai, Wen-Yen / Lin, Yenpo / Huang, Yen-Ling / Lu, Kuan-Ying / Chiang, Hsin-Ju / Schulte, Rolf F / Lin, Chien-Yuan Eddy / Lin, Gigin

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: The aim of this study was to explore the potential of magnetic resonance fingerprinting (MRF), an emerging quantitative MRI technique, in measuring relaxation values of female pelvic tissues compared to the conventional magnetic resonance image ... ...

    Abstract The aim of this study was to explore the potential of magnetic resonance fingerprinting (MRF), an emerging quantitative MRI technique, in measuring relaxation values of female pelvic tissues compared to the conventional magnetic resonance image compilation (MAGiC) sequence. The study included 32 female patients who underwent routine pelvic MRI exams using anterior and posterior array coils on a 3T clinical scanner. Our findings demonstrated significant correlations between MRF and MAGiC measured T1 and T2 values (
    Language English
    Publishing date 2023-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13132147
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  9. Article ; Online: Comparing Magnetic Resonance Fingerprinting (MRF) and the MAGiC Sequence for Simultaneous T1 and T2 Quantitative Measurements in the Female Pelvis

    Bo-Syuan Huang / Ching-Yi Hsieh / Wen-Yen Chai / Yenpo Lin / Yen-Ling Huang / Kuan-Ying Lu / Hsin-Ju Chiang / Rolf F. Schulte / Chien-Yuan Eddy Lin / Gigin Lin

    Diagnostics, Vol 13, Iss 2147, p

    A Prospective Study

    2023  Volume 2147

    Abstract: The aim of this study was to explore the potential of magnetic resonance fingerprinting (MRF), an emerging quantitative MRI technique, in measuring relaxation values of female pelvic tissues compared to the conventional magnetic resonance image ... ...

    Abstract The aim of this study was to explore the potential of magnetic resonance fingerprinting (MRF), an emerging quantitative MRI technique, in measuring relaxation values of female pelvic tissues compared to the conventional magnetic resonance image compilation (MAGiC) sequence. The study included 32 female patients who underwent routine pelvic MRI exams using anterior and posterior array coils on a 3T clinical scanner. Our findings demonstrated significant correlations between MRF and MAGiC measured T1 and T2 values ( p < 0.0001) for various pelvic tissues, including ilium, femoral head, gluteus, obturator, iliopsoas, erector spinae, uterus, cervix, and cutaneous fat. The tissue contrasts generated from conventional MRI and synthetic MRF also showed agreement in bone, muscle, and uterus for both T1-weighted and T2-weighted images. This study highlights the strengths of MRF in providing simultaneous T1 and T2 mapping. MRF offers distinct tissue contrast and has the potential for accurate diagnosis of female pelvic diseases, including tumors, fibroids, endometriosis, and pelvic inflammatory disease. Additionally, MRF shows promise in monitoring disease progression or treatment response. Overall, the study demonstrates the potential of MRF in the field of female pelvic organ imaging and suggests that it could be a valuable addition to the clinical practice of pelvic MRI exams. Further research is needed to establish the clinical utility of MRF and to develop standardized protocols for its implementation in clinical practice.
    Keywords computer-assisted image processing ; fingerprinting ; gynecology ; magnetic resonance imaging ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: The symptoms of autism including social communication deficits and repetitive and restricted behaviors are associated with different emotional and behavioral problems.

    Tsai, Ching-Hong / Chen, Kuan-Lin / Li, Hsing-Jung / Chen, Kuan-Hsu / Hsu, Chao-Wei / Lu, Chun-Hsiung / Hsieh, Kuan-Ying / Huang, Chien-Yu

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 20509

    Abstract: The aim of the study was to investigate the associations between symptoms of autism and emotional and behavioral problems in children with autism spectrum disorder from both caregivers' and clinicians' perspectives. Three main findings were found in our ... ...

    Abstract The aim of the study was to investigate the associations between symptoms of autism and emotional and behavioral problems in children with autism spectrum disorder from both caregivers' and clinicians' perspectives. Three main findings were found in our study. First, the association patterns were similar in the preschool and school-aged children. Second, different association patterns were found from caregivers' and professionals' perspectives. From the professionals' perspective, only repetitive behaviors were associated with behavioral problems, while from the caregivers' perspective, all symptoms of autism were associated with emotional and behavioral problems. Third, different types of symptoms of autism were associated with different types of emotional and behavioral problems. For example, from the professionals' perspective, restricted and repetitive behaviors were only associated with hyperactivity and inattention. From the caregivers' perspective, social emotion was associated with emotional symptoms, and other symptoms of autism were associated with hyperactivity and inattention, as well as with peer problems. The results of our study provided deeper understanding of the relationships between symptoms of autism and emotional and behavioral problems, and the findings could serve as a reference for intervention planning when clinicians approach children with autism spectrum disorder.
    MeSH term(s) Autism Spectrum Disorder/psychology ; Child ; Child, Preschool ; Emotions ; Female ; Humans ; Male ; Social Behavior ; Stereotyped Behavior ; Surveys and Questionnaires
    Language English
    Publishing date 2020-11-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-76292-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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