Article ; Online: Mesenchymal Stem Cell-Derived Extracellular Vesicles: Promising Treatment for COVID-19 Pandemic.
2021
Abstract: The pandemic of severe acute respiratory syndrome coronavirus-2 infection has prompted the urgent need for novel therapeutic approaches, especially for patients in critically severe conditions. To date, the pathogenesis of COVID-19 is not completely ... ...
Abstract | The pandemic of severe acute respiratory syndrome coronavirus-2 infection has prompted the urgent need for novel therapeutic approaches, especially for patients in critically severe conditions. To date, the pathogenesis of COVID-19 is not completely understood, and finding an effective new drug is still inconclusive. Mesenchymal stromal cell-derived extracellular vesicles contain large amounts of proteins, messenger RNA, and microRNAs that act as vehicles that transfer the cargo between cells. These nanotherapeutic materials exert anti-inflammatory effects on the immune system, which are necessary for subsidence of acute inflammation and promotion of tissue repair and regeneration. Therefore, the consideration of mesenchymal stromal cell-derived extracellular vesicles as a new, safe, and effective therapeutic approach in the treatment of COVID-19 pneumonia is suggested. |
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Language | English | |||||
Publishing date | 2021-02-23 | |||||
Publishing country | Turkey | |||||
Document type | Journal Article ; Review | |||||
ZDB-ID | 2396778-X | |||||
ISSN | 2146-8427 ; 1304-0855 | |||||
ISSN (online) | 2146-8427 | |||||
ISSN | 1304-0855 | |||||
DOI | 10.6002/ect.2020.0296 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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