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  1. Article ; Online: Aging trends in skin cancer: A long-term observational study in Japan.

    Nakamura, Anna / Kataoka, Kazuya / Takatsuka, Sumiko / Takenouchi, Tatsuya

    JAAD international

    2023  Volume 13, Page(s) 32–34

    Language English
    Publishing date 2023-07-22
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2023.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of total charge on the electronic structure of thiolate-protected X@Ag

    Nakamura, Katsunosuke / Ito, Shun / Koyasu, Kiichirou / Tsukuda, Tatsuya

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 8, Page(s) 5955–5959

    Abstract: Electronic structures of chemically synthesized silver-based clusters [ ... ...

    Abstract Electronic structures of chemically synthesized silver-based clusters [XAg
    Language English
    Publishing date 2023-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d2cp05079j
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  3. Article: The Effects of Boron Neutron Capture Therapy on the Lungs in Recurrent Breast Cancer Treatment.

    Kurosaki, Hiromasa / Okazaki, Keita / Takemori, Mihiro / Tate, Etsuko / Nakamura, Tatsuya

    Cureus

    2024  Volume 16, Issue 4, Page(s) e57417

    Abstract: Boron neutron capture therapy (BNCT) has predominantly been performed for brain tumors or head and neck cancers. Although BNCT is known to be applicable to breast cancer, it has only been performed in a few cases involving thoracic region irradiation ... ...

    Abstract Boron neutron capture therapy (BNCT) has predominantly been performed for brain tumors or head and neck cancers. Although BNCT is known to be applicable to breast cancer, it has only been performed in a few cases involving thoracic region irradiation with reactor-based BNCT systems. Thus, there are very few reports on the effects of BNCT on the thoracic region and no reports of BNCT for breast cancer with accelerator-based BNCT systems. This paper introduces the world's first clinical study employing an accelerator-based BNCT system targeting recurrent breast cancer after radiation therapy. We aim to assess the efficacy and safety of BNCT, focusing on the dose response in the thoracic region, especially concerning the potential for radiation pneumonitis. Preliminary findings from the first three cases indicate no evidence of radiation pneumonitis within three months post treatment. This study not only establishes a foundation for novel breast cancer treatment options but also contributes significantly to the field of BNCT in the thoracic region.
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.57417
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  4. Article ; Online: Propagation graph estimation from individuals' time series of observed states.

    Hayashi, Tatsuya / Nakamura, Atsuyoshi

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 6078

    Abstract: Various things propagate through the medium of individuals. Some individuals follow the others and take the states similar to their states a small number of time steps later. In this paper, we study the problem of estimating the state propagation order ... ...

    Abstract Various things propagate through the medium of individuals. Some individuals follow the others and take the states similar to their states a small number of time steps later. In this paper, we study the problem of estimating the state propagation order of individuals from the real-valued state sequences of all the individuals.We propose a method of constructing a state propagation graph from individuals' time series of observed states. The propagation order estimated by our proposed method is demonstrated to be significantly more accurate than that by a baseline method (optimal constant delay model) for our synthetic datasets, and also to be consistent with visually recognizable propagation orders for the dataset of Japanese stock price time series and biological cell firing state sequences.
    MeSH term(s) Algorithms ; Humans ; Time Factors
    Language English
    Publishing date 2022-04-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-10031-3
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  5. Article ; Online: Propagation graph estimation from individuals’ time series of observed states

    Tatsuya Hayashi / Atsuyoshi Nakamura

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 13

    Abstract: Abstract Various things propagate through the medium of individuals. Some individuals follow the others and take the states similar to their states a small number of time steps later. In this paper, we study the problem of estimating the state ... ...

    Abstract Abstract Various things propagate through the medium of individuals. Some individuals follow the others and take the states similar to their states a small number of time steps later. In this paper, we study the problem of estimating the state propagation order of individuals from the real-valued state sequences of all the individuals.We propose a method of constructing a state propagation graph from individuals’ time series of observed states. The propagation order estimated by our proposed method is demonstrated to be significantly more accurate than that by a baseline method (optimal constant delay model) for our synthetic datasets, and also to be consistent with visually recognizable propagation orders for the dataset of Japanese stock price time series and biological cell firing state sequences.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Efficient alignment-based average delay time estimation in fluctuating delayed propagation

    Atsuyoshi Nakamura / Tatsuya Hayashi

    Array, Vol 15, Iss , Pp 100240- (2022)

    2022  

    Abstract: We propose an alignment-based average delay time estimation algorithm between two time series in the propagation of time-varying delay. Though the number of the minimum cost alignments may be exponential in the length of the time series, the proposed ... ...

    Abstract We propose an alignment-based average delay time estimation algorithm between two time series in the propagation of time-varying delay. Though the number of the minimum cost alignments may be exponential in the length of the time series, the proposed algorithm takes account of all such alignments, and as a post-alignment process, it runs in time linear in the number of the nodes in the minimum cost alignment graph, which is at most the length squared. The efficiency of our algorithm is confirmed through numerical experiments compared to the naive enumeration algorithm using recursive calls to traverse the graph.
    Keywords Alignment ; Time delay estimation ; Dynamic time warping ; Dynamic programming ; Computer engineering. Computer hardware ; TK7885-7895 ; Electronic computers. Computer science ; QA75.5-76.95
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Positive association between the proinsulin-to-C-peptide ratio and prolonged hyperglycemic time in type 2 diabetes.

    Miya, Aika / Nakamura, Akinobu / Nomoto, Hiroshi / Kameda, Hiraku / Atsumi, Tatsuya

    Endocrine journal

    2024  Volume 71, Issue 4, Page(s) 403–408

    Abstract: The proinsulin-to-C-peptide (PI:C) ratio is an index applied during the early stage of pancreatic β-cell dysfunction. The aim of this study was to identify the characteristics associated with the PI:C ratio to discuss pancreatic β-cell dysfunction ... ...

    Abstract The proinsulin-to-C-peptide (PI:C) ratio is an index applied during the early stage of pancreatic β-cell dysfunction. The aim of this study was to identify the characteristics associated with the PI:C ratio to discuss pancreatic β-cell dysfunction progression during the natural course of type 2 diabetes and its relationship with glycemic management. This multicenter, prospective observational study included 272 outpatients with type 2 diabetes. Continuous glucose monitoring was performed and fasting blood samples were collected and analyzed. We identified the clinical factors associated with the PI:C ratio by multiple regression analysis. The mean age of the cohort was 68.0 years, mean hemoglobin A1c 7.1% (54 mmol/mol), and mean body mass index 24.9 kg/m
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Female ; Male ; Proinsulin/blood ; Aged ; C-Peptide/blood ; Middle Aged ; Hyperglycemia/blood ; Prospective Studies ; Blood Glucose/metabolism ; Blood Glucose/analysis ; Body Mass Index ; Glycated Hemoglobin/analysis ; Glycated Hemoglobin/metabolism ; Insulin-Secreting Cells/metabolism ; Blood Glucose Self-Monitoring
    Chemical Substances Proinsulin (9035-68-1) ; C-Peptide ; Blood Glucose ; Glycated Hemoglobin
    Language English
    Publishing date 2024-03-23
    Publishing country Japan
    Document type Journal Article ; Observational Study ; Multicenter Study
    ZDB-ID 1151918-6
    ISSN 1348-4540 ; 0918-8959
    ISSN (online) 1348-4540
    ISSN 0918-8959
    DOI 10.1507/endocrj.EJ23-0525
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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  8. Article ; Online: Understanding Flexdispersion: Structure-Function Relationship Studies of Organic Amphiphilic Ligands.

    Sudo, Tatsuya / Sagawa, Masahiko / Adachi, Sota / Kato, Yusuke / Nakanishi, Yuki / Nakamura, Tatsuya / Yamashita, Shohei / Kamiya, Hidehiro / Okada, Yohei

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e202304324

    Abstract: Since inorganic nanoparticles have unique properties that differ from bulk materials, their material applications have attracted attention in various fields. In order to utilize inorganic nanoparticles for functional materials, they must be dispersed ... ...

    Abstract Since inorganic nanoparticles have unique properties that differ from bulk materials, their material applications have attracted attention in various fields. In order to utilize inorganic nanoparticles for functional materials, they must be dispersed without agglomeration. Therefore, the surfaces of inorganic nanoparticles are typically modified with organic ligands to improve their dispersibility. Nevertheless, the relationship between the tail group structure in organic ligands and the dispersibility of inorganic nanoparticles in organic solvents remains poorly understood. We previously developed amphiphilic ligands that consist of ethylene glycol chains and alkyl chains to disperse inorganic nanoparticles in a variety of organic solvents. However, the structural requirements for amphiphilic ligands to "flexibly" disperse nanoparticles in less polar to polar solvents are still unclear. Here, we designed and synthesized several phosphonic acid ligands for structure‒function relationship studies of flexdispersion. Dynamic light scattering analysis and visible light transmittance measurements revealed that the ratio of alkyl/ethylene glycol chains in organic ligands alone does not determine the dispersibility of the nanoparticles in organic solvents, but the arrangement of the individual chains also has an effect. From a practical application standpoint, it is preferable to design ligands with ethylene glycol chains on the outside relative to the particle surface.
    Language English
    Publishing date 2024-04-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202304324
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  9. Article ; Online: Supervalence Bonding in Bi-icosahedral Cores of [M

    Ito, Emi / Ito, Shun / Takano, Shinjiro / Nakamura, Toshikazu / Tsukuda, Tatsuya

    JACS Au

    2022  Volume 2, Issue 11, Page(s) 2627–2634

    Abstract: ... ...

    Abstract Au
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3704
    ISSN (online) 2691-3704
    DOI 10.1021/jacsau.2c00519
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  10. Article ; Online: Atmospheric formaldehyde production on early Mars leading to a potential formation of bio-important molecules.

    Koyama, Shungo / Kamada, Arihiro / Furukawa, Yoshihiro / Terada, Naoki / Nakamura, Yuki / Yoshida, Tatsuya / Kuroda, Takeshi / Vandaele, Ann Carine

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2397

    Abstract: Formaldehyde ( ... ...

    Abstract Formaldehyde (H
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52718-9
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