LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 198

Search options

  1. Book: Risk, chance, and causation

    Bracken, Michael B.

    investigating the origins and treatment of disease

    2013  

    Abstract: ... noted epidemiologist Michael Bracken clearly communicates how clinical epidemiology works. Using ... everyday terms, Bracken describes how professional scientists approach questions of disease causation and ...

    Author's details Michael B. Bracken
    Abstract "The press and other media constantly report news stories about dangerous chemicals in the environment, miracle cures, the safety of therapeutic treatments, and potential cancer-causing agents. But what exactly is actually meant by "increased risk" should we worry if we are told that we are at twice the risk of developing an illness? And how do we interpret "reduced risk" to properly assess the benefits of noisily touted dietary supplements? Demonstrating the difficulty of separating the hype from the hypothesis, noted epidemiologist Michael Bracken clearly communicates how clinical epidemiology works. Using everyday terms, Bracken describes how professional scientists approach questions of disease causation and therapeutic efficacy to provide readers with the tools to help them understand whether warnings of environmental risk are truly warranted, or if claims of therapeutic benefit are justified."--Provided by publisher
    Keywords Disease / etiology ; Risk Factors ; Therapeutics
    Language English
    Size XIII, 330 S. : Ill.
    Publisher Yale Univ. Press
    Publishing place New Haven u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017537747
    ISBN 978-0-300-18884-4 ; 0-300-18884-6
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 1939 available for loan (reading room) Lesesaal EG

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Random-Effects Assumption in Meta-analyses.

    Bracken, Michael B

    JAMA

    2019  Volume 322, Issue 1, Page(s) 81

    MeSH term(s) Computer Simulation ; Models, Statistical
    Language English
    Publishing date 2019-07-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2019.5443
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.88: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: SSRIs and autism: interpreting an umbrella review.

    Bracken, Michael B

    The lancet. Psychiatry

    2019  Volume 6, Issue 11, Page(s) 893

    MeSH term(s) Autistic Disorder ; Humans ; Serotonin Uptake Inhibitors
    Chemical Substances Serotonin Uptake Inhibitors
    Language English
    Publishing date 2019-10-21
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(19)30392-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Disseminated Histoplasmosis Causing Temporally and Spatially Discrete Gastrointestinal Perforations in an HIV-Negative Patient.

    Zaskey, Michael / Burns, Bracken

    The American surgeon

    2024  , Page(s) 31348241227189

    Abstract: Histoplasma ... ...

    Abstract Histoplasma capsulatum
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348241227189
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.106: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Meta-analysis requires independent observations and freedom from bias.

    Bracken, Michael B

    British journal of clinical pharmacology

    2016  Volume 81, Issue 6, Page(s) 1191–1193

    MeSH term(s) Bias ; Freedom ; Humans ; Meta-Analysis as Topic ; Publication Bias
    Language English
    Publishing date 2016-03-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 188974-6
    ISSN 1365-2125 ; 0306-5251 ; 0264-3774
    ISSN (online) 1365-2125
    ISSN 0306-5251 ; 0264-3774
    DOI 10.1111/bcp.12898
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1118: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Potential confounding still clouds the possible association of maternal caffeine intake and low birth weight.

    Bracken, Michael B

    Evidence-based medicine

    2015  Volume 20, Issue 1, Page(s) 37

    MeSH term(s) Birth Weight/drug effects ; Caffeine/adverse effects ; Female ; Humans ; Infant, Low Birth Weight ; Male ; Pregnancy ; Prenatal Exposure Delayed Effects
    Chemical Substances Caffeine (3G6A5W338E)
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1324346-9
    ISSN 1473-6810 ; 1356-5524
    ISSN (online) 1473-6810
    ISSN 1356-5524
    DOI 10.1136/ebmed-2014-110116
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4793: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Case-control studies require appropriate population controls: an example of error in the SSRI birth defect literature.

    Bracken, Michael B

    European journal of epidemiology

    2015  Volume 30, Issue 11, Page(s) 1217–1218

    MeSH term(s) Abnormalities, Drug-Induced/epidemiology ; Depression/drug therapy ; Female ; Humans ; Pregnancy ; Pregnancy Complications/chemically induced ; Prenatal Exposure Delayed Effects/epidemiology ; Serotonin Uptake Inhibitors/adverse effects ; Serotonin Uptake Inhibitors/therapeutic use
    Chemical Substances Serotonin Uptake Inhibitors
    Language English
    Publishing date 2015-11
    Publishing country Netherlands
    Document type Comment ; Letter
    ZDB-ID 632614-6
    ISSN 1573-7284 ; 0393-2990
    ISSN (online) 1573-7284
    ISSN 0393-2990
    DOI 10.1007/s10654-015-0097-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2090: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Epidemiology as a liberal art: from graduate school to middle school, an unfulfilled agenda.

    Bracken, Michael B

    Annals of epidemiology

    2014  Volume 24, Issue 3, Page(s) 171–173

    Abstract: Calls by Lilienfeld, Fraser, and others some three decades ago to introduce epidemiology into undergraduate college education remain largely unfulfilled. Consideration of epidemiology as a "liberal art" has also led to exploring possibilities for ... ...

    Abstract Calls by Lilienfeld, Fraser, and others some three decades ago to introduce epidemiology into undergraduate college education remain largely unfulfilled. Consideration of epidemiology as a "liberal art" has also led to exploring possibilities for introducing epidemiology into early education: to high and even middle schools. Adding epidemiology to school curricula should help educate the public to understand science-based evidence concerning the causes and treatments of disease, help inoculate them against a tsunami of biased and fraudulent media messaging, and permit advancing postgraduate education in epidemiology to even higher levels of scholarship.
    MeSH term(s) Curriculum ; Epidemiology/education ; Humans ; Public Health/education ; Schools ; Universities
    Language English
    Publishing date 2014-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074355-8
    ISSN 1873-2585 ; 1047-2797
    ISSN (online) 1873-2585
    ISSN 1047-2797
    DOI 10.1016/j.annepidem.2013.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3225: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Preregistration of epidemiology protocols: a commentary in support.

    Bracken, Michael B

    Epidemiology (Cambridge, Mass.)

    2011  Volume 22, Issue 2, Page(s) 135–137

    MeSH term(s) Epidemiologic Studies ; Registries ; Research Design
    Language English
    Publishing date 2011-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 1053263-8
    ISSN 1531-5487 ; 1044-3983
    ISSN (online) 1531-5487
    ISSN 1044-3983
    DOI 10.1097/EDE.0b013e318207fc7c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Steroids for acute spinal cord injury.

    Bracken, Michael B

    The Cochrane database of systematic reviews

    2012  Volume 1, Page(s) CD001046

    Abstract: Background: Acute spinal cord injury is a devastating condition typically affecting young people, mostly males. Steroid treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient's ...

    Abstract Background: Acute spinal cord injury is a devastating condition typically affecting young people, mostly males. Steroid treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient's life.
    Objectives: To review randomized trials of steroids for human acute spinal cord injury.
    Search methods: We searched the Cochrane Injuries Group Specialised Register (searched 02 Aug 2011), The Cochrane Central Register of Controlled Trials 2011, issue 3 (The Cochrane Library), MEDLINE (Ovid) 1948 to July Week 3 2011, EMBASE (Ovid) 1974 to 2011 week 17, ISI Web of Science: Science Citation Index Expanded (SCI-EXPANDED) 1970 to Aug 2011, ISI Web of Science: Conference Proceedings Citation Index- Science (CPCI-S) 1990 to Aug 2011 and PubMed [www.ncbi.nlm.nih.gov/sites/entrez/] (searched 04 Aug 2011) for records added to PubMed in the last 90 days). Files of the National Acute Spinal Cord Injury Study (NASCIS) were reviewed (NASCIS was founded in 1977 and has tracked trials in this area since that date). We also searched the reference lists of relevant studies and previously published reviews.
    Selection criteria: All randomized controlled trials of steroid treatment for acute spinal cord injury in any language.
    Data collection and analysis: One review author extracted data from trial reports. Japanese and French studies were found through NASCIS and additional data (e.g. SDs) were obtained from the original study authors.
    Main results: Eight trials are included in this review, seven used methylprednisolone. Methylprednisolone sodium succinate has been shown to improve neurologic outcome up to one year post-injury if administered within eight hours of injury and in a dose regimen of: bolus 30mg/kg over 15 minutes, with maintenance infusion of 5.4 mg/kg per hour infused for 23 hours. The initial North American trial results were replicated in a Japanese trial but not in the one from France. Data was obtained from the latter studies to permit appropriate meta-analysis of all three trials. This indicated significant recovery in motor function after methylprednisolone therapy, when administration commenced within eight hours of injury. A more recent trial indicates that, if methylprednisolone therapy is given for an additional 24 hours (a total of 48 hours), additional improvement in motor neurologic function and functional status are observed. This is particularly observed if treatment cannot be started until between three to eight hours after injury. The same methylprednisolone therapy has been found effective in whiplash injuries. A modified regimen was found to improve recovery after surgery for lumbar disc disease. The risk of bias was low in the largest methyprednisolne trials. Overall, there was no evidence of significantly increased complications or mortality from the 23 or 48 hour therapy.
    Authors' conclusions: High-dose methylprednisolone steroid therapy is the only pharmacologic therapy shown to have efficacy in a phase three randomized trial when administered within eight hours of injury. One trial indicates additional benefit by extending the maintenance dose from 24 to 48 hours, if start of treatment must be delayed to between three and eight hours after injury. There is an urgent need for more randomized trials of pharmacologic therapy for acute spinal cord injury.
    MeSH term(s) Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/therapeutic use ; Drug Administration Schedule ; Glucocorticoids/administration & dosage ; Glucocorticoids/therapeutic use ; Humans ; Methylprednisolone/administration & dosage ; Methylprednisolone/therapeutic use ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/therapeutic use ; Nimodipine/administration & dosage ; Nimodipine/therapeutic use ; Randomized Controlled Trials as Topic ; Spinal Cord Injuries/drug therapy
    Chemical Substances Anti-Inflammatory Agents ; Glucocorticoids ; Neuroprotective Agents ; Nimodipine (57WA9QZ5WH) ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2012-01-18
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ISSN 1469-493X
    ISSN (online) 1469-493X
    DOI 10.1002/14651858.CD001046.pub2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top