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  1. Book ; Online: Evidence-Based Research in Pediatric Nutrition

    Szajewska, H.

    (World Review of Nutrition and Dietetics ; Vol.108)

    2013  

    Series title World Review of Nutrition and Dietetics ; Vol.108
    Keywords Nutrition ; Pediatrics ; Clinical Nutrition ; Neonatology
    Language English
    Size 1 Online-Ressource (X + 112 S.)
    Publisher S. Karger
    Publishing place Basel
    Document type Book ; Online
    Note A summary of current knowledge and unresolved issues
    HBZ-ID HT019543303
    ISBN 978-3-318-02457-9 ; 3-318-02457-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Selected Human Milk Oligosaccharides Added to Infant Formulas for Term Infants.

    Szajewska, Hania

    Nestle Nutrition Institute workshop series

    2022  Volume 96, Page(s) 149–159

    Abstract: The benefits of breastfeeding, such as reduced risk of gastrointestinal and respiratory tract infections, depend largely on the presence of bioactive compounds in breast milk, including human milk oligosaccharides (HMOs). The presence of HMOs represents ... ...

    Abstract The benefits of breastfeeding, such as reduced risk of gastrointestinal and respiratory tract infections, depend largely on the presence of bioactive compounds in breast milk, including human milk oligosaccharides (HMOs). The presence of HMOs represents one of the largest differences in composition between breast milk and infant formula. Currently, progress in biotechnology allows the production of selected HMOs such as 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT), which are increasingly being added to infant formulas to narrow the difference between breast milk and formula. It is important to differentiate HMOs naturally occurring in human breast milk from those biotechnologically produced, which, while identical to HMOs in breast milk, do not originate from breast milk. This chapter summarizes basic facts about HMOs, findings from observational studies assessing the relationship between specific HMOs and clinical effects, and evidence from randomized controlled trials with structures identical to HMOs in breast milk added to infant formulas. Overall, the findings from some recently published trials provide reassurance that infant formulas supplemented with selected structures identical to HMOs, specifically 2'-FL with/out LNnT, are safe and well tolerated, and may have favorable effects on some health outcomes and medication usage. Further studies are needed.
    MeSH term(s) Breast Feeding ; Female ; Humans ; Infant ; Infant Formula/chemistry ; Milk, Human/chemistry ; Oligosaccharides/analysis
    Chemical Substances Oligosaccharides
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1664-2155
    ISSN (online) 1664-2155
    DOI 10.1159/000519388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Gut Microbiota: No Longer the Forgotten Organ.

    Szajewska, Hania

    Annals of nutrition & metabolism

    2021  , Page(s) 1–2

    Language English
    Publishing date 2021-09-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 392341-1
    ISSN 1421-9697 ; 0250-6807 ; 1018-9688
    ISSN (online) 1421-9697
    ISSN 0250-6807 ; 1018-9688
    DOI 10.1159/000519223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.260: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Book: Evidence based research in pediatric nutrition

    Szajewska, Hania / Shamir, Raanan

    and 8 tables

    (World Review of Nutrition and Dietetics ; 108)

    2013  

    Title variant Evidence-based research in pediatric nutrition
    Author's details Vol. ed. Hania Szajewska ; Raanan Shamir
    Series title World Review of Nutrition and Dietetics ; 108
    World review of nutrition and dietetics
    Collection World review of nutrition and dietetics
    Keywords Child Nutritional Physiological Phenomena ; Diet Therapy ; Food ; Evidence-Based Medicine ; Kind ; Ernährung
    Subject Nutrition ; Ernährungsstatus ; Ernährungszustand ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language English
    Size X, 111 S. : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT017781466
    ISBN 978-3-318-02456-2 ; 3-318-02456-2 ; 9783318024579 ; 3318024570
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 2675 available for loan (reading room) Lesesaal EG

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  5. Article ; Online: Gut microbiota is a hot and fast-moving topic, and paediatricians need to monitor the latest developments.

    Szajewska, Hania

    Acta paediatrica (Oslo, Norway : 1992)

    2019  Volume 108, Issue 11, Page(s) 1934–1935

    MeSH term(s) Child ; Gastrointestinal Microbiome ; Gastrointestinal Tract ; Humans ; Microbiota ; Monitoring, Physiologic ; Pediatricians
    Language English
    Publishing date 2019-09-06
    Publishing country Norway
    Document type Editorial ; Comment
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.14960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.95: Show issues Location:
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  6. Article ; Online: Evidence-Based Medicine and Clinical Research: Both Are Needed, Neither Is Perfect.

    Szajewska, Hania

    Annals of nutrition & metabolism

    2018  Volume 72 Suppl 3, Page(s) 13–23

    Abstract: Currently, it is impossible to think of modern healthcare that ignores evidence-based medicine (EBM), a concept which relies on 3 pillars: individual clinical expertise, the values and desires of the patient, and the best available research. However, EBM ...

    Abstract Currently, it is impossible to think of modern healthcare that ignores evidence-based medicine (EBM), a concept which relies on 3 pillars: individual clinical expertise, the values and desires of the patient, and the best available research. However, EBM is not perfect. Clinical research is also far from being perfect. This article provides an overview of the basic principles, opportunities, and controversies offered by EBM. It also summarizes current discussions on clinical research. Potential solutions to the problems of EBM and clinical research are discussed as well. If there were specific issues related to pediatric nutrition, an attempt was made to discuss the basic principles and limitations in this context. However, the conclusions are applicable to EBM and clinical research in general. In the future, considering that new ways of obtaining health data will continue to emerge, the world of EBM and clinical research is likely to change. The ultimate goal, however, will remain the same: improving health outcomes for patients.
    MeSH term(s) Biomedical Research/standards ; Child Nutrition Sciences ; Conflict of Interest ; Delivery of Health Care/methods ; Evidence-Based Medicine/standards ; Humans ; Research Design/standards ; Research Support as Topic
    Language English
    Publishing date 2018-04-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392341-1
    ISSN 1421-9697 ; 0250-6807 ; 1018-9688
    ISSN (online) 1421-9697
    ISSN 0250-6807 ; 1018-9688
    DOI 10.1159/000487375
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.260: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Evidence on postbiotics in infants and children.

    Szajewska, Hania / Salminen, Seppo

    Current opinion in clinical nutrition and metabolic care

    2022  Volume 26, Issue 3, Page(s) 253–258

    Abstract: Purpose of review: The aim is to provide updated information on the concept of postbiotics and recent data on the efficacy of postbiotics for the prevention and treatment of childhood diseases.: Recent findings: In line with a recently proposed ... ...

    Abstract Purpose of review: The aim is to provide updated information on the concept of postbiotics and recent data on the efficacy of postbiotics for the prevention and treatment of childhood diseases.
    Recent findings: In line with a recently proposed consensus definition, a postbiotic is 'a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host'. Although inanimate, postbiotics may exert health benefits. There are only limited data on infant formulas containing postbiotics, but they are well tolerated, support adequate growth and demonstrate no potential identifiable risks, although clinical benefits remain limited. Currently, there is only limited support for postbiotic use for treating diarrhoea and preventing common paediatric infectious diseases in young children. Given the limited evidence, sometimes with a high risk of bias, caution is justified. No data in older children and adolescents are available.
    Summary: The consensus definition of postbiotics facilitates further research. As not all postbiotics are the same, the type of disease and specific postbiotic studied should be considered when choosing postbiotics for the prevention or treatment of childhood diseases. Additional studies are needed to assess disease conditions responsive to postbiotics. Mechanisms of action of postbiotics need to be evaluated and characterized.
    MeSH term(s) Adolescent ; Infant ; Humans ; Child ; Child, Preschool ; Infant Formula ; Diarrhea
    Language English
    Publishing date 2022-12-30
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1460178-3
    ISSN 1473-6519 ; 1363-1950
    ISSN (online) 1473-6519
    ISSN 1363-1950
    DOI 10.1097/MCO.0000000000000909
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5586: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Evaluating the impact of lactase supplementation on infant colic: Study protocol for a systematic review of randomized controlled trials.

    Kozłowska-Jalowska, Anna / Stróżyk, Agata / Horvath, Andrea / Szajewska, Hania

    JPGN reports

    2024  Volume 5, Issue 1, Page(s) 5–9

    Abstract: Infant colic is a common functional gastrointestinal disorder that affects infants during their first months of life. The etiology of this condition remains unclear. However, some studies suggest lactase deficiency may be a contributing factor. Currently, ...

    Abstract Infant colic is a common functional gastrointestinal disorder that affects infants during their first months of life. The etiology of this condition remains unclear. However, some studies suggest lactase deficiency may be a contributing factor. Currently, the evidence on dietary treatment and lactase supplementation for management of infant colic is limited. We aim to systematically review evidence on the efficacy and safety of using a lactase supplementation for managing infant colic. The Cochrane Central Register of Controlled Trials (CENTRAL, the Cochrane Library), MEDLINE, and EMBASE will be searched to identify randomized controlled trials comparing oral lactase supplementation with placebo or no intervention in infants aged less than 6-month-old with infant colic using any recognized definition. The risk of bias will be assessed using the second version of the Cochrane Collaboration's risk-of-bias tool. The main outcome will be the number of responders in each group after treatment, defined as infants who experienced a decrease in daily crying as reported by the study authors. Additional outcomes will include the duration and frequency of crying episodes, infant sleep duration, parental satisfaction, discomfort of infants, number of hospital admissions, family quality of life, and adverse events during the intervention. The study findings will be published in a peer-reviewed journal and will be submitted to relevant conferences.
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2691-171X
    ISSN (online) 2691-171X
    DOI 10.1002/jpr3.12024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of lactase supplementation on infant colic: Systematic review of randomized controlled trials.

    Kozłowska-Jalowska, Anna / Stróżyk, Agata / Horvath, Andrea / Szajewska, Hania

    Journal of pediatric gastroenterology and nutrition

    2024  Volume 78, Issue 5, Page(s) 1009–1016

    Abstract: To systematically review evidence on the efficacy and safety of using a lactase supplementation for managing infant colic. The MEDLINE, EMBASE, and Cochrane Library databases were searched (up to September 2023) for randomized controlled trials (RCTs) ... ...

    Abstract To systematically review evidence on the efficacy and safety of using a lactase supplementation for managing infant colic. The MEDLINE, EMBASE, and Cochrane Library databases were searched (up to September 2023) for randomized controlled trials (RCTs) comparing oral lactase supplementation with placebo or no intervention in infants younger than 6 months old with infant colic. The risk of bias was assessed using the revised version of the Cochrane risk-of-bias tool. Outcomes measured were selected according to a standardized core outcome set. Five RCTs involving a total of 391 infants were identified. Three RCTs reported reduced crying duration, but one showed effect only in a compliant group (40.4%, p = 0.0052). A meta-analysis of two RCTs found no difference in crying duration and fussing time during 1 week of lactase treatment compared with placebo (mean difference [MD] -17.66 min/day, 95% confidence interval [CI], -60.8 to 25.5; I
    MeSH term(s) Humans ; Colic ; Lactase ; Infant ; Randomized Controlled Trials as Topic ; Dietary Supplements ; Infant, Newborn ; Crying ; Treatment Outcome
    Chemical Substances Lactase (EC 3.2.1.108)
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't ; Meta-Analysis ; Review
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1002/jpn3.12144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1728: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Reply to Mazela et al. Comment on "Jankiewicz et al. The Effect of Goat-Milk-Based Infant Formulas on Growth and Safety Parameters: A Systematic Review and Meta-Analysis.

    Jankiewicz, Mateusz / van der Zee, Lucie / Szajewska, Hania

    Nutrients

    2023  Volume 15, Issue 21

    Abstract: Thank you for carefully reading and commenting [ ... ]. ...

    Abstract Thank you for carefully reading and commenting [...].
    Language English
    Publishing date 2023-10-27
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15214559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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