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  1. Article ; Online: Perceptions of preparedness, timing of cancer diagnosis, and objective emergency preparedness among gynecological cancer patients in Puerto Rico before and after Hurricane Maria.

    Johnson, Meghan / Parada, Humberto / Ferran, Karen / Perez, Ramona / Calo, William / Sant'Ana, Istoni da Luz / Ocasio, Liz Martínez / Mendez-Lazaro, Pablo A / Garcia, Sandra I / Tortolero-Luna, Guillermo / Umpierre, Sharee A / Ortiz, Ana Patricia

    Journal of cancer policy

    2023  Volume 36, Page(s) 100415

    Abstract: ... cancers before or after the 2017 Hurricanes Irma and Maria in Puerto Rico.: Methods: This study ...

    Abstract Objectives: This study investigated the impact of cancer diagnosis status, individual feelings of preparedness, and other covariates on objective emergency preparedness among women diagnosed with gynecological cancers before or after the 2017 Hurricanes Irma and Maria in Puerto Rico.
    Methods: This study included 240 women who were interviewed by telephone from 9/2019-11/2020. Objective emergency preparedness was assessed using a list of six items. Subjective emergency preparedness was assessed by asking the women how prepared they felt (well, somewhat, or not at all) to face an emergency. Crude and multivariable logistic regression analyses were conducted to assess the associations (odds ratios [ORs] and 95% confidence intervals [CIs]) between variables of interest and objective preparedness.
    Results: Before and after the hurricanes, 60% and 66% of women, respectively, were objectively prepared. Before the hurricanes, women reporting feeling well-prepared (vs. not prepared) (OR=9.31, 95%CI:3.96-21.91) and those who were diagnosed before (vs. after) the hurricanes (OR=1.71, 95%CI:0.95-3.09) were more likely to be objectively prepared. After the hurricanes, self-perceived well-preparedness (OR=2.46, 95% CI: 1.10-5.51) was positively associated with emergency preparedness when compared to feeling unprepared.
    Conclusions: Perceptions of emergency preparedness and having a cancer diagnosis increased the likelihood of being objectively prepared for an emergency.
    Policy summary: This study demonstrates the need for state, territorial, and federal governments to include emergency preparedness plans for cancer patients in the Comprehensive Cancer Control plans. The study also indicates a need for cancer specific emergency preparedness information to be readily available for patients.
    MeSH term(s) Humans ; Female ; Puerto Rico/epidemiology ; Cyclonic Storms ; Civil Defense ; Emotions ; Neoplasms
    Language English
    Publishing date 2023-02-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2213-5383
    ISSN (online) 2213-5383
    DOI 10.1016/j.jcpo.2023.100415
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  2. Article ; Online: Interaction Between Caffeine and Creatine When Used as Concurrent Ergogenic Supplements: A Systematic Review.

    Elosegui, Sara / López-Seoane, Jaime / Martínez-Ferrán, María / Pareja-Galeano, Helios

    International journal of sport nutrition and exercise metabolism

    2022  Volume 32, Issue 4, Page(s) 285–295

    Abstract: There is some controversy regarding the interactions between creatine (CRE) and caffeine (CAF) supplements. The aim of this systematic review was to study whether such ergogenic interaction occurs and to analyze the protocol to optimize their synchronous ...

    Abstract There is some controversy regarding the interactions between creatine (CRE) and caffeine (CAF) supplements. The aim of this systematic review was to study whether such ergogenic interaction occurs and to analyze the protocol to optimize their synchronous use. The PubMed, Web of Science, MEDLINE, CINAHL, and SPORTDiscus databases were searched until November 2021 following the PRISMA guidelines. Ten studies were included. Three studies observed that CRE loading before an acute dose of CAF before exercise did not interfere in the beneficial effect of CAF, whereas one study reported that only an acute supplementation (SUP) of CAF was beneficial but not the acute SUP of both. When chronic SUP with CRE + CAF was used, two studies reported that CAF interfered in the beneficial effect of CRE, whereas three studies did not report interaction between concurrent SUP, and one study reported synergy. Possible mechanisms of interaction are opposite effects on relaxation time and gastrointestinal distress derived from concurrent SUP. CRE loading does not seem to interfere in the acute effect of CAF. However, chronic SUP of CAF during CRE loading could interfere in the beneficial effect of CRE.
    MeSH term(s) Athletic Performance ; Caffeine/pharmacology ; Creatine/pharmacology ; Dietary Supplements ; Humans ; Performance-Enhancing Substances
    Chemical Substances Performance-Enhancing Substances ; Caffeine (3G6A5W338E) ; Creatine (MU72812GK0)
    Language English
    Publishing date 2022-01-11
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1101115-4
    ISSN 1543-2742 ; 1050-1606 ; 1526-484X
    ISSN (online) 1543-2742
    ISSN 1050-1606 ; 1526-484X
    DOI 10.1123/ijsnem.2021-0262
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  3. Article ; Online: Rhodiola rosea supplementation on sports performance: A systematic review of randomized controlled trials.

    Sanz-Barrio, Patricia M / Noreen, Eric E / Gilsanz-Estebaranz, Laura / Lorenzo-Calvo, Jorge / Martínez-Ferrán, María / Pareja-Galeano, Helios

    Phytotherapy research : PTR

    2023  Volume 37, Issue 10, Page(s) 4414–4428

    Abstract: The aim of this systematic review was to determine whether the supplementation with Rhodiola rosea (RR), an herb that has been used for centuries for its various properties, can have an effect on muscle damage and physical performance. The databases ... ...

    Abstract The aim of this systematic review was to determine whether the supplementation with Rhodiola rosea (RR), an herb that has been used for centuries for its various properties, can have an effect on muscle damage and physical performance. The databases PubMed, Web of Science, and Cochrane Library were used to find studies published until March 2023. Randomized controlled trials, healthy participants, and no use of other supplements. The search strategy was conducted by two independent reviewers, and specific information was extracted from the selected studies. Thirteen studies were included with 263 participants (198 men and 65 women between 18 and 65 years old). Two studies followed acute supplementation, 5 chronic, and 6 combined both. The results were heterogenous, having 11 studies with some positive effects, while 2 studies show no effect in variables such as rating of perceive exertion, heart rate, antioxidant capacity, blood lactate, creatine kinase, or C-reactive protein. Two limitations were found, firstly, the difference between supplementation and exercise protocols, and secondly, the existence of unclear or high risk of bias in most of the studies included. Acute supplementation with RR has a positive effect on endurance performance and rating of perceived exertion (RPE). Chronic supplementation has a positive effect on anaerobic exercise performance, but not endurance exercise performance. Chronic supplementation may positively impact muscle damage during exercise. However, more high-quality studies are needed to firmly establish the clinical efficacy of RR.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Antioxidants ; Dietary Supplements ; Exercise/physiology ; Randomized Controlled Trials as Topic ; Rhodiola
    Chemical Substances Antioxidants
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.7950
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  4. Article ; Online: Estimating fat-free mass in recreationally resistance-trained young men: Longitudinal and cross-sectional validation of different methods.

    Martínez-Ferrán, María / Berlanga, Luis A / Barcelo-Guido, Olga / Matos-Duarte, Michelle / Vicente-Campos, Davinia / Jorge, Sandra Sánchez / Romero-Morales, Carlos / Casla-Barrio, Soraya / Munguía-Izquierdo, Diego / Pareja-Galeano, Helios

    Nutrition research (New York, N.Y.)

    2023  Volume 117, Page(s) 38–47

    Abstract: Several techniques exist to measure fat-free mass (FFM). Accordingly, this study is based on data from our recent trial comparing the sensitivity of the main field methods available with that of dual-energy X-ray absorptiometry (DXA) as reference and ... ...

    Abstract Several techniques exist to measure fat-free mass (FFM). Accordingly, this study is based on data from our recent trial comparing the sensitivity of the main field methods available with that of dual-energy X-ray absorptiometry (DXA) as reference and analyzing the cross-sectional accuracy of these field methods in recreationally resistance-trained males. We hypothesized that the use of these techniques would lead to varying estimates of FFM compared with DXA. Participants (N = 23; 21.4 ± 3.3 years) completed a 10-week resistance training plus diet intervention designed to optimize hypertrophy. FFM was determined by bioelectrical impedance analysis (BIA), 23 anthropometric equations, and DXA. After the intervention, FFM increased significantly according to BIA and most anthropometric estimates, but this increase was not detected by 2 anthropometric equations or by DXA. Only 1 of these 2 equations showed significant correlation with DXA and no standardized or significant differences to this reference method, although it did display significant heteroscedasticity. In our cross-sectional analysis, only 1 anthropometric equation gave rise to good accuracy as confirmed by DXA. Our findings indicate that the use of different techniques to assess FFM gains in response to a hypertrophic intervention yields different results. BIA with general embedded equations should not be used to monitor a young male adult's body composition. To monitor FFM over time, we would recommend the Dunne et al. equation (2) as the most sensitive field method, and to assess FFM cross-sectionally, equation (1) of these authors is the most accurate field method.
    MeSH term(s) Adult ; Humans ; Male ; Cross-Sectional Studies ; Electric Impedance ; Reproducibility of Results ; Body Composition/physiology ; Anthropometry/methods ; Absorptiometry, Photon/methods ; Body Mass Index
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2023.05.005
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  5. Article ; Online: Estimating fat-free mass in recreationally resistance-trained young men: Longitudinal and cross-sectional validation of different methods

    Martínez-Ferrán, María / Berlanga, Luis A. / Barcelo-Guido, Olga / Matos-Duarte, Michelle / Vicente Campos, Davinia / Jorge, Sandra Sánchez / Romero-Morales, Carlos / Casla-Barrio, Soraya / Munguía Izquierdo, Diego / Pareja-Galeano, Helios

    Nutrition Research. 2023 Sept., v. 117 p.38-47

    2023  

    Abstract: Several techniques exist to measure fat-free mass (FFM). Accordingly, this study is based on data from our recent trial comparing the sensitivity of the main field methods available with that of dual-energy X-ray absorptiometry (DXA) as reference and ... ...

    Abstract Several techniques exist to measure fat-free mass (FFM). Accordingly, this study is based on data from our recent trial comparing the sensitivity of the main field methods available with that of dual-energy X-ray absorptiometry (DXA) as reference and analyzing the cross-sectional accuracy of these field methods in recreationally resistance-trained males. We hypothesized that the use of these techniques would lead to varying estimates of FFM compared with DXA. Participants (N = 23; 21.4 ± 3.3 years) completed a 10-week resistance training plus diet intervention designed to optimize hypertrophy. FFM was determined by bioelectrical impedance analysis (BIA), 23 anthropometric equations, and DXA. After the intervention, FFM increased significantly according to BIA and most anthropometric estimates, but this increase was not detected by 2 anthropometric equations or by DXA. Only 1 of these 2 equations showed significant correlation with DXA and no standardized or significant differences to this reference method, although it did display significant heteroscedasticity. In our cross-sectional analysis, only 1 anthropometric equation gave rise to good accuracy as confirmed by DXA. Our findings indicate that the use of different techniques to assess FFM gains in response to a hypertrophic intervention yields different results. BIA with general embedded equations should not be used to monitor a young male adult's body composition. To monitor FFM over time, we would recommend the Dunne et al. equation (2) as the most sensitive field method, and to assess FFM cross-sectionally, equation (1) of these authors is the most accurate field method.
    Keywords adults ; bioelectrical impedance ; cross-sectional studies ; dual-energy X-ray absorptiometry ; equations ; field methods ; heteroskedasticity ; hypertrophy ; lean body mass ; males ; nutrition research ; nutritional intervention ; Lean mass ; Strength training ; Anthropometry ; Dual X-ray absorptiometry ; %BF ; BIA ; BM ; BMI ; DXA ; FFM ; ISAK ; SKF
    Language English
    Dates of publication 2023-09
    Size p. 38-47.
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2023.05.005
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  6. Article ; Online: Physical Condition and Risk of Hospitalization and Polypharmacy in Older Adults.

    Fernández-Araque, Ana / García-de-Diego, Laura / Martínez-Ferrán, María / Diez-Vega, Ignacio / Yvert, Thomas / Mingo-Gómez, Maria Teresa / Santiago, Catalina / Pareja-Galeano, Helios / Verde, Zoraida

    Rejuvenation research

    2022  Volume 25, Issue 4, Page(s) 200–206

    Abstract: Hospitalization in older population leads to a decline in physical function, physical condition, and independency. However, a scarce number of studies has addressed the effect of being in good physical condition on the risk of hospitalization and ... ...

    Abstract Hospitalization in older population leads to a decline in physical function, physical condition, and independency. However, a scarce number of studies has addressed the effect of being in good physical condition on the risk of hospitalization and polypharmacy in older people. Therefore, this study aims to examine the relationship between physical condition and other health factors, and the incidence of hospitalization and polypharmacy in Spanish older persons. For this cross-sectional study we recruited 102 institutionalized persons aged 80 years or older, who were being treated at three primary care centers. The data collected were number of hospitalizations and medications, dietary habits, nutrition status, quality of life, independence in activities of daily life, physical performance, and associated genotype data. Scoring higher in the tests Chair stand and 8-Foot Up-and-go was found associated with reduced risks of hospitalization (odds ratio [OR] = 0.45 [95% CI = 0.2-0.99]; OR 0.32 [95% CI = 0.12-0.86]) and polypharmacy (OR = 0.36 [95% CI = 0.16-0.8]; OR = 0.28 [95% CI = 0.1-0.78]). The number of medications was also lower in individuals with a greater aerobic capacity and activities of daily life independence (OR = 0.28 [95% CI = 0.1-0.78]; OR = 0.37 [95% CI = 0.16-0.82]). No associations were found with the remaining physical performance tests or other factors assessed. Our findings point to benefits of greater strength, balance, and aerobic capacity in terms of reducing the risk of hospitalization and polypharmacy.
    MeSH term(s) Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Hospitalization ; Humans ; Odds Ratio ; Polypharmacy ; Quality of Life
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2150779-X
    ISSN 1557-8577 ; 1549-1684
    ISSN (online) 1557-8577
    ISSN 1549-1684
    DOI 10.1089/rej.2021.0030
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  7. Article ; Online: Antioxidant vitamin supplementation on muscle adaptations to resistance training: A double-blind, randomized controlled trial.

    Martínez-Ferrán, María / Berlanga, Luis A / Barcelo-Guido, Olga / Matos-Duarte, Michelle / Vicente-Campos, Davinia / Sánchez-Jorge, Sandra / Romero-Morales, Carlos / Munguía-Izquierdo, Diego / Pareja-Galeano, Helios

    Nutrition (Burbank, Los Angeles County, Calif.)

    2022  Volume 105, Page(s) 111848

    Abstract: Objectives: The aim of this study was to examine whether antioxidant vitamin supplementation with vitamin C (VitC) and vitamin E (VitE) affects the hypertrophic and functional adaptations to resistance training in trained men.: Methods: This was a ... ...

    Abstract Objectives: The aim of this study was to examine whether antioxidant vitamin supplementation with vitamin C (VitC) and vitamin E (VitE) affects the hypertrophic and functional adaptations to resistance training in trained men.
    Methods: This was a double-blind, randomized controlled trial in which participants were supplemented daily with VitC and VitE ( n = 12) or placebo ( n = 11) while completing a 10-wk resistance training program accompanied by a dietary intervention (300 kcal surplus and adequate protein intake) designed to optimize hypertrophy. Body composition (dual-energy x-ray absorptiometry), handgrip strength, and one-repetition maximum (1-RM), maximal force (F0), velocity (V0), and power (Pmax) were measured in bench press (BP) and squat (SQ) tests conducted before and after the intervention. To detect between-group differences, multiple-mixed analysis of variance, standardized differences, and qualitative differences were estimated. Relative changes within each group were assessed using a paired Student's t test.
    Results: In both groups, similar improvements were produced in BP 1-RM , SQ 1-RM SQ, and BP F0 (P < 0.05) after the resistance training program. A small effect size was observed for BP 1-RM (d = 0.53), BP F0 (d = 0.48), and SQ 1-RM (d = -0.39), but not for SQ F0 (d = 0.03). Dominant handgrip strength was significantly increased only in the placebo group (P < 0.05). According to body composition data, a significant increase was produced in upper body fat-free mass soft tissue (FFMST; P < 0.05) in the placebo group, whereas neither total nor segmental FFMST was increased in the vitamin group. Small intervention effect sizes were observed for upper body FFSMT (d = 0.32), non-dominant and dominant leg FFMST (d = -0.39; d = -0.42). Although a significant increase in total body fat was observed in both groups (P < 0.05) only the placebo group showed an increase in visceral adipose tissue (P < 0.05), showing a substantial intervention effect (d = 0.85).
    Conclusions: The data indicated that, although VitC/VitE supplementation seemed to blunt upper body strength and hypertrophy adaptations to resistance training, it could also mitigate gains in visceral adipose tissue elicited by an energy surplus.
    MeSH term(s) Male ; Humans ; Resistance Training ; Antioxidants/pharmacology ; Muscle Strength/physiology ; Hand Strength ; Muscle, Skeletal ; Body Composition/physiology ; Dietary Supplements ; Double-Blind Method ; Vitamin E/pharmacology ; Ascorbic Acid/pharmacology ; Vitamins/pharmacology ; Hypertrophy
    Chemical Substances Antioxidants ; Vitamin E (1406-18-4) ; Ascorbic Acid (PQ6CK8PD0R) ; Vitamins
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2022.111848
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  8. Article ; Online: Effects of Acute Vitamin C plus Vitamin E Supplementation on Exercise-Induced Muscle Damage in Runners: A Double-Blind Randomized Controlled Trial.

    Martínez-Ferrán, María / Cuadrado-Peñafiel, Víctor / Sánchez-Andreo, Juan Manuel / Villar-Lucas, Marta / Castellanos-Montealegre, Mónica / Rubio-Martín, Agustín / Romero-Morales, Carlos / Casla-Barrio, Soraya / Pareja-Galeano, Helios

    Nutrients

    2022  Volume 14, Issue 21

    Abstract: Considering the existing controversy over the possible role of acute antioxidant vitamins in reducing exercise-induced muscle damage (EIMD), this doubled-blind, randomized and controlled trial aimed to determine whether supplementation with vitamins C ... ...

    Abstract Considering the existing controversy over the possible role of acute antioxidant vitamins in reducing exercise-induced muscle damage (EIMD), this doubled-blind, randomized and controlled trial aimed to determine whether supplementation with vitamins C and E could mitigate the EIMD in endurance-trained runners (n = 18). The exercise protocol involved a warm-up followed by 6 to 8 bouts of 1 km running at 75% maximum heart rate (HRmax). Two hours before the exercise protocol, participants took the supplementation with vitamins or placebo, and immediately afterwards, blood lactate, rate of perceived exertion and performance were assessed. At 24 h post-exercise, CK, delayed onset muscle soreness and performance were determined (countermovement jump, squat jump and stiffness test). The elastic index and vertical stiffness were calculated using a stiffness test. Immediately after the exercise protocol, all participants showed improved maximum countermovement jump, which only persisted after 24 h in the vitamin group (p < 0.05). In both groups, squat jump height was significantly greater (p < 0.05) immediately after exercise and returned to baseline values after 24 h. The elastic index increased in the vitamin group (p < 0.05), but not in the placebo group. In both groups, lactate levels increased from pre- to immediately post-exercise (p < 0.05), and CK increased from pre- to 24 h post-exercise (p < 0.05). No significant differences between groups were observed in any of the variables (p > 0.05). Vitamin C and E supplementation does not seem to help with EIMD in endurance-trained individuals.
    MeSH term(s) Humans ; Muscle, Skeletal ; Myalgia/etiology ; Myalgia/prevention & control ; Ascorbic Acid/pharmacology ; Vitamins/pharmacology ; Double-Blind Method ; Vitamin E/pharmacology ; Dietary Supplements ; Lactates/pharmacology
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Vitamins ; Vitamin E (1406-18-4) ; Lactates
    Language English
    Publishing date 2022-11-03
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14214635
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  9. Article: Antioxidant vitamins supplementation on muscle adaptations to resistance training: A double-blind randomized controlled trial

    Martínez-Ferrán, María / Berlanga, Luis A / Barcelo-Guido, Olga / Matos-Duarte, Michelle / Vicente-Campos, Davinia / Sánchez Jorge, Sandra / Romero-Morales, Carlos / Munguía-Izquierdo, Diego / Pareja-Galeano, Helios

    Nutrition. 2022 Sept. 05,

    2022  

    Abstract: This double-blind randomized controlled trial examines whether antioxidant vitamin supplementation with vitamin C (VitC) and vitamin E (VitE) affects the hypertrophic and functional adaptations to resistance training in trained men. : Participants were ...

    Abstract : This double-blind randomized controlled trial examines whether antioxidant vitamin supplementation with vitamin C (VitC) and vitamin E (VitE) affects the hypertrophic and functional adaptations to resistance training in trained men. : Participants were daily supplemented with VitC and VitE (VIT; N=12) or placebo (PLA; N=11) while completing a 10-week resistance training programme accompanied by a dietary intervention (300 kcal surplus and adequate protein intake) designed to optimize hypertrophy. Body composition (dual-energy X-ray absorptiometry), handgrip strength, and one-repetition maximum (1-RM), maximal force (F0), velocity (V0) and power (Pmax) were measured in bench press (BP) and squat (SQ) tests conducted before and after the intervention. To detect between-group differences, multiple-mixed ANOVA, standardized differences and qualitative differences were estimated. Relative changes within each group were assessed using a paired Student's t test. : In both groups, similar improvements were produced in 1-RM (BP), 1-RM (SQ) and F0 (BP) (p<0.05) after resistance training program. A small effect size was observed for 1-RM (BP) (d=0.53), F0 (BP) (d=0.48) and 1-RM (SQ) (d=-0.39), but not for F0 (SQ) (d=0.03). Dominant hand grip strength was significantly increased only in the PLA group (p<0.05). According to body composition data, a significant increase was produced in upper body fat-free mass soft tissue (FFMST; p<0.05) in PLA, while neither total nor segmental FFMST was increased in the VIT group. Small intervention effect sizes were observed for upper body FFSMT (d=0.32), non-dominant and dominant leg FFMST (d=-0.39; d=-0.42). While a significant increase in total body fat was observed in both groups (p<0.05) only the PLA group showed an increase in visceral adipose tissue (VAT; p<0.05), showing a substantial intervention effect (d=0.85). : Our data indicate that, while VitC/VitE supplementation seems to blunt the upper body strength and hypertrophy adaptations to resistance training, it could also mitigate VAT gains elicited by an energy surplus.
    Keywords adipose tissue ; antioxidants ; ascorbic acid ; body fat ; dual-energy X-ray absorptiometry ; energy ; hand strength ; hypertrophy ; lean body mass ; muscles ; nutritional intervention ; placebos ; protein intake ; t-test ; vitamin E ; vitamin supplements
    Language English
    Dates of publication 2022-0905
    Publishing place Elsevier Inc.
    Document type Article
    Note Pre-press version
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2022.111848
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: N-3 PUFA as an ergogenic supplement modulating muscle hypertrophy and strength: a systematic review.

    López-Seoane, Jaime / Martinez-Ferran, María / Romero-Morales, Carlos / Pareja-Galeano, Helios

    Critical reviews in food science and nutrition

    2021  Volume 62, Issue 32, Page(s) 9000–9020

    Abstract: There is growing evidence that suggests that n-3 polyunsaturated fatty acids (PUFA) may improve physical performance when combined with proper training through modulation of muscle hypertrophy, muscle strength, and delayed onset muscle soreness (DOMS). ... ...

    Abstract There is growing evidence that suggests that n-3 polyunsaturated fatty acids (PUFA) may improve physical performance when combined with proper training through modulation of muscle hypertrophy, muscle strength, and delayed onset muscle soreness (DOMS). This systematic review aims to examine the effect and optimal dosage of n-3 PUFA supplementation on muscle hypertrophy, muscle strength, and DOMS when combined with physical exercise. The PubMed, Web of Science, MEDLINE Complete, CINAHL and SPORTDiscus databases were searched following the PRISMA guidelines. Randomized controlled trials performed with healthy humans were considered. Fifteen studies with a total of 461 individuals were included in this systematic review. All of them measured muscle function (short physical performance test, range of motion (ROM), electromechanical delay (EMD), muscle echo intensity or muscle quality) and DOMS. Fourteen studies evaluated muscle strength and only six assessed muscle hypertrophy. Our results demonstrated that n-3 PUFA does not improve muscle hypertrophy, muscle strength or skeletal muscle biomarkers of inflammation and muscle damage beyond the benefits obtained by the training itself. Nevertheless, n-3 PUFA improves DOMS recovery and muscle function (measured by ROM, EMD and muscle quality).
    MeSH term(s) Humans ; Fatty Acids, Omega-3/pharmacology ; Dietary Supplements ; Myalgia/drug therapy ; Myalgia/prevention & control ; Muscle, Skeletal/physiology ; Hypertrophy
    Chemical Substances Fatty Acids, Omega-3
    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2021.1939262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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