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Article ; Online: Prevalence of "Ghost Infarct Core" after Endovascular Thrombectomy.

Ospel, Johanna M / Rex, Nathaniel / Rinkel, Leon / Kashani, Nima / Buck, Brian / Rempel, Jeremy / Sahlas, Demetrios / Kelly, Michael E / Budzik, Ron / Tymianski, Michael / Hill, Michael D / Goyal, Mayank

AJNR. American journal of neuroradiology

2024 Volume 45, Issue 3, Page(s) 291–295

Abstract: Background and purpose: Baseline CTP sometimes overestimates the size of the infarct core ("ghost core" phenomenon). We investigated how often CTP overestimates infarct core compared with 24-hour imaging, and aimed to characterize the patient subgroup ... ...

Abstract	Background and purpose: Baseline CTP sometimes overestimates the size of the infarct core ("ghost core" phenomenon). We investigated how often CTP overestimates infarct core compared with 24-hour imaging, and aimed to characterize the patient subgroup in whom a ghost core is most likely to occur. Materials and methods: Data are from the randomized controlled ESCAPE-NA1 trial, in which patients with acute ischemic stroke undergoing endovascular treatment were randomized to intravenous nerinetide or placebo. Patients with available baseline CTP and 24-hour follow-up imaging were included in the analysis. Ghost infarct core was defined as CTP core volume minus 24-hour infarct volume > 10 mL). Clinical characteristics of patients with versus without ghost core were compared. Associations of ghost core and clinical characteristics were assessed by using multivariable logistic regression. Results: A total of 421 of 1105 patients (38.1%) were included in the analysis. Forty-seven (11.2%) had a ghost core > 10 mL, with a median ghost infarct volume of 13.4 mL (interquartile range 7.6-26.8). Young patient age, complete recanalization, short last known well to CT times, and possibly male sex were associated with ghost infarct core. Conclusions: CTP ghost core occurred in ∼1 of 10 patients, indicating that CTP frequently overestimates the infarct core size at baseline, particularly in young patients with complete recanalization and short ischemia duration.
MeSH term(s)	Humans ; Male ; Brain Ischemia/therapy ; Cerebral Infarction ; Ischemic Stroke ; Prevalence ; Stroke/therapy ; Thrombectomy/methods ; Tomography, X-Ray Computed/methods ; Treatment Outcome ; Female ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2024-03-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	603808-6
ISSN	1936-959X ; 0195-6108
ISSN (online)	1936-959X
ISSN	0195-6108
DOI	10.3174/ajnr.A8113
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Article ; Online: Implantable vs Prolonged External Electrocardiographic Monitoring for Atrial Fibrillation Detection in Patients With Ischemic Stroke-Reply.

Buck, Brian H / Hill, Michael D / Exner, Derek V

JAMA

2021 Volume 326, Issue 14, Page(s) 1439–1440

MeSH term(s)	Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Brain Ischemia/diagnosis ; Humans ; Ischemic Attack, Transient ; Ischemic Stroke ; Stroke
Language	English
Publishing date	2021-09-06
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2958-0
ISSN	1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
ISSN (online)	1538-3598
ISSN	0254-9077 ; 0002-9955 ; 0098-7484
DOI	10.1001/jama.2021.13490
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Article ; Online: The effects of non‐crop habitat on spotted wing drosophila (Drosophila suzukii) abundance in fruit systems: A meta‐analysis

Buck, Nicolas / Fountain, Michelle / Potts, Simon G. / Bishop, Jacob / Garratt, Michael P. D.

Agricultural and Forest Entomology. 2023 Feb., v. 25, no. 1 p.66-76

2023

Abstract: Drosophila suzukii (SWD) poses a threat to soft and stone fruit globally. SWD inhabits non‐crop areas adjacent to farms from where it moves into crops to cause damage. Effective IPM control strategies, considering both the crop and non‐crop area, are ... ...

Abstract	Drosophila suzukii (SWD) poses a threat to soft and stone fruit globally. SWD inhabits non‐crop areas adjacent to farms from where it moves into crops to cause damage. Effective IPM control strategies, considering both the crop and non‐crop area, are needed to control this economically important pest. We conducted a meta‐analysis to quantify the impacts of different non‐crop habitats around fruit farms on SWD populations, comparing abundance of SWD trapped in crop and non‐crop habitats. Overall, SWD abundance was greater in non‐crop habitats than in cropped areas and this difference was greatest in farms adjacent to woodland, or field margins containing known SWD host plants. The difference in SWD abundance between crop and non‐crop habitats was not affected by crop type but was greatest in the winter months and in conventional compared to organic farms, indicating conventional approaches can reduce relative SWD abundance. Drosophila suzukii overwinter in non‐crop habitats which provide refuge outside the cropping season. However, certain habitats support greater relative abundance of SWD than others and this is also affected by farm management. We discuss what these findings mean for effective control of SWD.
Keywords	Drosophila suzukii ; entomology ; farm management ; forests ; fruits ; habitats ; meta-analysis ; pests ; stone fruits ; woodlands
Language	English
Dates of publication	2023-02
Size	p. 66-76.
Publishing place	Blackwell Publishing Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	1444210-3
ISSN	1461-9563 ; 1461-9555
ISSN (online)	1461-9563
ISSN	1461-9555
DOI	10.1111/afe.12531
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Quantifying abnormal emotion processing: A novel computational assessment method and application in schizophrenia.

Bradley, Ellen R / Portanova, Jake / Woolley, Josh D / Buck, Benjamin / Painter, Ian S / Hankin, Michael / Xu, Weizhe / Cohen, Trevor

Psychiatry research

2024 Volume 336, Page(s) 115893

Abstract: Abnormal emotion processing is a core feature of schizophrenia spectrum disorders (SSDs) that encompasses multiple operations. While deficits in some areas have been well-characterized, we understand less about abnormalities in the emotion processing ... ...

Abstract	Abnormal emotion processing is a core feature of schizophrenia spectrum disorders (SSDs) that encompasses multiple operations. While deficits in some areas have been well-characterized, we understand less about abnormalities in the emotion processing that happens through language, which is highly relevant for social life. Here, we introduce a novel method using deep learning to estimate emotion processing rapidly from spoken language, testing this approach in male-identified patients with SSDs (n = 37) and healthy controls (n = 51). Using free responses to evocative stimuli, we derived a measure of appropriateness, or "emotional alignment" (EA). We examined psychometric characteristics of EA and its sensitivity to a single-dose challenge of oxytocin, a neuropeptide shown to enhance the salience of socioemotional information in SSDs. Patients showed impaired EA relative to controls, and impairment correlated with poorer social cognitive skill and more severe motivation and pleasure deficits. Adding EA to a logistic regression model with language-based measures of formal thought disorder (FTD) improved classification of patients versus controls. Lastly, oxytocin administration improved EA but not FTD among patients. While additional validation work is needed, these initial results suggest that an automated assay using spoken language may be a promising approach to assess emotion processing in SSDs.
Language	English
Publishing date	2024-04-04
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2024.115893
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Article ; Online: Older Adults' Preferences Regarding Firearm Locking Device Use: Results of a National Survey.

Villarreal, Ricardo I / Stanley, Ian H / Anestis, Michael D / Buck-Atkinson, Jessica / Betz, Marian E

Clinical gerontologist

2023 , Page(s) 1–11

Abstract: Objectives: Use of firearm locking devices may reduce the risk of suicide and injury among older adults. This study describes older adults' preferences when choosing a firearm locking device.: Methods: We conducted a secondary analysis of a ... ...

Abstract	Objectives: Use of firearm locking devices may reduce the risk of suicide and injury among older adults. This study describes older adults' preferences when choosing a firearm locking device. Methods: We conducted a secondary analysis of a nationally representative survey of US adult firearm owners ( Results: The top three factors cited as impacting firearm locking device selection included speed (53.6%) and ease of firearm access from device (52.4%), and cost of the device (28.7%). These top factors were comparable for all adults across genders. A larger proportion of older vs younger males reported that a primary preference was whether the device allows the firearm to remain loaded with ammunition; smaller proportions of older vs younger males reported strength of device (device durability) and costs. Conclusions: Preference among older adults, particularly older males, for locking devices that maintain the firearms easy to access - especially, loaded with ammunition - might impact firearm injury prevention efforts for this high-risk group. Clinical implications: For harm reduction, use of any firearm locking device may reduce the risk of firearm injury or death. Clinicians are encouraged to explore reasons for locking device selection within motivational interviewing frameworks.
Language	English
Publishing date	2023-11-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	226146-7
ISSN	1545-2301 ; 0731-7115
ISSN (online)	1545-2301
ISSN	0731-7115
DOI	10.1080/07317115.2023.2285994
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Article: Corrigendum: How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis.

Chaisinanunkul, Napasri / Khurshid, Shaan / Buck, Brian H / Rabinstein, Alejandro A / Anderson, Christopher D / Hill, Michael D / Fugate, Jennifer E / Saver, Jeffrey L

Frontiers in neurology

2023 Volume 14, Page(s) 1206563

Abstract: This corrects the article DOI: 10.3389/fneur.2023.1103664.]. ...

Abstract	[This corrects the article DOI: 10.3389/fneur.2023.1103664.].
Language	English
Publishing date	2023-05-10
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2023.1206563
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Article ; Online: Expanding the Transuranic Metal-Organic Framework Portfolio: The Optical Properties of Americium(III) MOF-76.

Arteaga, Ana / Nicholas, Aaron D / Sinnwell, Michael A / McNamara, Bruce K / Buck, Edgar C / Surbella, Robert G

Inorganic chemistry

2023 Volume 62, Issue 51, Page(s) 21036–21043

Abstract: Reported is the synthesis, crystal structure, and solid-state characterization of a new americium containing metal-organic framework (MOF), [Am( ... ...

Abstract	Reported is the synthesis, crystal structure, and solid-state characterization of a new americium containing metal-organic framework (MOF), [Am(C
Language	English
Publishing date	2023-12-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1484438-2
ISSN	1520-510X ; 0020-1669
ISSN (online)	1520-510X
ISSN	0020-1669
DOI	10.1021/acs.inorgchem.3c02742
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Article ; Online: p53, cancer and the immune response.

Blagih, Julianna / Buck, Michael D / Vousden, Karen H

Journal of cell science

2020 Volume 133, Issue 5

Abstract: The importance of cancer-cell-autonomous functions of the tumour suppressor p53 (encoded ... ...

Abstract	The importance of cancer-cell-autonomous functions of the tumour suppressor p53 (encoded by
MeSH term(s)	Humans ; Immunity ; Mutation ; Neoplasms/genetics ; Tumor Suppressor Protein p53/genetics
Chemical Substances	Tumor Suppressor Protein p53
Language	English
Publishing date	2020-03-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2993-2
ISSN	1477-9137 ; 0021-9533
ISSN (online)	1477-9137
ISSN	0021-9533
DOI	10.1242/jcs.237453
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Zs.A 1200: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 14: Show issues

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Article: How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis.

Chaisinanunkul, Napasri / Khurshid, Shaan / Buck, Brian H / Rabinstein, Alejandro A / Anderson, Christopher D / Hill, Michael D / Fugate, Jennifer E / Saver, Jeffrey L

Frontiers in neurology

2023 Volume 14, Page(s) 1103664

Abstract: Introduction: Long-term cardiac monitoring studies have unveiled low-burden, occult atrial fibrillation (AF) in some patients with otherwise cryptogenic stroke (CS), but occult AF is also found in some individuals without a stroke history and in ... ...

Abstract	Introduction: Long-term cardiac monitoring studies have unveiled low-burden, occult atrial fibrillation (AF) in some patients with otherwise cryptogenic stroke (CS), but occult AF is also found in some individuals without a stroke history and in patients with stroke of a known cause (KS). Clinical management would be aided by estimates of how often occult AF in a patient with CS is causal vs. incidental. Methods: Through a systematic search, we identified all case-control and cohort studies applying identical long-term monitoring techniques to both patients with CS and KS. We performed a random-effects meta-analysis across these studies to determine the best estimate of the differential frequency of occult AF in CS and KS among all patients and across age subgroups. We then applied Bayes' theorem to determine the probability that occult AF is causal or incidental. Results: The systematic search identified three case-control and cohort studies enrolling 560 patients (315 CS, 245 KS). Methods of long-term monitoring were implantable loop recorder in 31.0%, extended external monitoring in 67.9%, and both in 1.2%. Crude cumulative rates of AF detection were CS 47/315 (14.9%) vs. KS 23/246 (9.3%). In the formal meta-analysis, the summary odds ratio for occult AF in CS vs. KS in all patients was 1.80 (95% CI, 1.05-3.07), Conclusion: Current evidence is preliminary, but it indicates that in cryptogenic stroke when occult AF is found, it is causal in about 38.2% of patients. These findings suggest that anticoagulation therapy may be beneficial to prevent recurrent stroke in a substantial proportion of patients with CS found to have occult AF.
Language	English
Publishing date	2023-03-14
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2023.1103664
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Military community engagement to prevent firearm-related violence: adaptation of project safe guard for service members.

Kennedy, S Rachel / Buck-Atkinson, Jessica / Moceri-Brooks, Jayna / Johnson, Megan L / Anestis, Michael D / Carrington, Makala / Baker, Justin C / Fisher, Mary E / Nease, Donald E / Bryan, AnnaBelle O / Bryan, Craig J / Betz, Marian E

Injury epidemiology

2024 Volume 11, Issue 1, Page(s) 7

Abstract: Background: Suicide, especially by firearm, remains a leading cause of death in military populations in the USA. Reducing access to firearms, especially during high risk times, may help prevent suicide and other forms of violence. The purpose of this ... ...

Abstract	Background: Suicide, especially by firearm, remains a leading cause of death in military populations in the USA. Reducing access to firearms, especially during high risk times, may help prevent suicide and other forms of violence. The purpose of this study was to adapt a promising existing lethal means safety intervention (Project Safe Guard, PSG) for cross-cutting violence prevention and peer support in active-duty service communities using community engagement methods. Methods: A two-pronged community-engaged research approach was employed, including the Community Translation (CT) process that engaged 15 Service Members from one installation to help adapt PSG successfully. In addition, qualitative data was collected from 40 active-duty service members and military violence prevention specialists through in-depth interviews and focus group discussions. Results: Qualitative data and CT feedback led to site-specific PSG adaptations. Participants emphasized the importance of peer-to-peer discussions and highlighted resource allocation, leadership support, and stigma on firearm ownership as potential implementation challenges. Conclusions: Findings demonstrate the feasibility of community-engaged research to adapt lethal means safety interventions within military populations. PSG implementation should consider resource allocation, leadership support, and addressing stigma. This study has implications for future policies and standards for performing research on sensitive topics, particularly among military populations.
Language	English
Publishing date	2024-02-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2764253-7
ISSN	2197-1714
ISSN	2197-1714
DOI	10.1186/s40621-024-00490-9
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