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  1. Book ; Online: Tecnologías de información y teletrabajo; su estado en Colombia

    Valdés Castro, Edgar / Castillo Tabares, Rubén / Duran Peralta, Julián / García González, Carlos Alberto / Astudillo Villegas, Ricardo

    2018  

    Keywords Development economics & emerging economies ; Investigación ; Gestión Empresarial ; Gestión Ambiental ; Competitividad
    Language 0|s
    Size 1 electronic resource (73-97 pages)
    Publisher Universidad Santiago de Cali
    Publishing place Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021610419
    ISBN 978-958-5522-70-1 ; 958-5522-70-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Omics approaches to investigate the neuroprotective capacity of a Citrus sinensis (sweet orange) extract in a Caenorhabditis elegans Alzheimer's model.

    Sánchez-Martínez, José David / Cifuentes, Alejandro / Valdés, Alberto

    Food research international (Ottawa, Ont.)

    2023  Volume 172, Page(s) 113128

    Abstract: Citrus sinensis by-products are a promising source of neuroprotective molecules. In this study, a pressurized liquid extract of Citrus by-products (PLE100) has been extensively characterized, and its neuroprotective capacity tested in the Caenorhabditis ... ...

    Abstract Citrus sinensis by-products are a promising source of neuroprotective molecules. In this study, a pressurized liquid extract of Citrus by-products (PLE100) has been extensively characterized, and its neuroprotective capacity tested in the Caenorhabditis elegans strain CL4176, a validated in vivo model of Alzheimer's disease (AD). More than 450 compounds have been annotated in the extract, being triacylglycerols (TGs), stigmastanes, fatty acids (FAs) and carbohydrates the most abundant. The results demonstrate that worms PLE100-treated are significantly protected in a dose-dependent manner against the Aβ-peptide paralysis toxicity. The RNA-Seq data showed an alteration of 294 genes mainly related to the stress response defense along with genes involved in the lipid transport and metabolism. Moreover, the comprehensive metabolomics study allowed the identification of 818 intracellular metabolites, of which 54 were significantly altered (mainly lipids). The integration of these and previous results provides with new evidences of the protection mechanisms of this promising extract.
    MeSH term(s) Animals ; Citrus sinensis ; Alzheimer Disease/drug therapy ; Caenorhabditis elegans ; Citrus ; Plant Extracts/pharmacology
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2023-06-12
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.113128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2972: Show issues

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  3. Article ; Online: Restorative Parental Discipline and Types of Defending Bystander Intervention in Cyberbullying: The Mediate Role of Justice Sensitivity.

    García-Vázquez, Fernanda Inéz / Valdés-Cuervo, Angel Alberto / León-Parada, María Dolores / Parra-Pérez, Lizeth Guadalupe

    Cyberpsychology, behavior and social networking

    2024  

    Abstract: Parental socialization strategies are critical in explaining adolescents' online behavior. This study examined the relationships between parental restorative discipline, observed justice sensitivity, and cyber-bystander defender intervention ( ... ...

    Abstract Parental socialization strategies are critical in explaining adolescents' online behavior. This study examined the relationships between parental restorative discipline, observed justice sensitivity, and cyber-bystander defender intervention (constructive and aggressive) in cyberbullying. The sample comprised 900 Mexican adolescents (40.2% male and 58.8% female), of which 450 were from secondary school (
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2545735-4
    ISSN 2152-2723 ; 2152-2715
    ISSN (online) 2152-2723
    ISSN 2152-2715
    DOI 10.1089/cyber.2023.0445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: In vivo neuroprotective capacity of a Dunaliella salina extract - comprehensive transcriptomics and metabolomics study.

    Valdés, Alberto / Sánchez-Martínez, José David / Gallego, Rocío / Ibáñez, Elena / Herrero, Miguel / Cifuentes, Alejandro

    NPJ science of food

    2024  Volume 8, Issue 1, Page(s) 4

    Abstract: In this study, an exhaustive chemical characterization of a Dunaliella salina (DS) microalga extract obtained using supercritical fluids has been performed, and its neuroprotective capacity has been evaluated in vivo using an Alzheimer's disease (AD) ... ...

    Abstract In this study, an exhaustive chemical characterization of a Dunaliella salina (DS) microalga extract obtained using supercritical fluids has been performed, and its neuroprotective capacity has been evaluated in vivo using an Alzheimer's disease (AD) transgenic model of Caenorhabditis elegans (strain CL4176). More than 350 compounds were annotated in the studied DS extract, with triacylglycerols, free fatty acids (FAs), carotenoids, apocarotenoids and glycerol being the most abundant. DS extract significantly protects C. elegans in a dose-dependent manner against Aβ-peptide paralysis toxicity, after 32 h, 53% of treated worms at 50 µg/mL were not paralyzed. This concentration was selected to further evaluate the transcriptomics and metabolomics changes after 26 h by using advanced analytical methodologies. The RNA-Seq data showed an alteration of 150 genes, mainly related to the stress and detoxification responses, and the retinol and lipid metabolism. The comprehensive metabolomics and lipidomics analyses allowed the identification of 793 intracellular metabolites, of which 69 were significantly altered compared to non-treated control animals. Among them, different unsaturated FAs, lysophosphatidylethanolamines, nucleosides, dipeptides and modified amino acids that have been previously reported as beneficial during AD progression, were assigned. These compounds could explain the neuroprotective capacity observed, thus, providing with new evidences of the protection mechanisms of this promising extract.
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ISSN 2396-8370
    ISSN (online) 2396-8370
    DOI 10.1038/s41538-023-00246-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Clavipectoral fascia plane block in midshaft clavicle fractures: A cadaveric study.

    Labandeyra, Hipólito / Heredia, Cristina / Váldes-Vilches, Luis Fernando / Prats-Galino, Alberto / Sala-Blanch, Xavier

    Journal of clinical anesthesia

    2024  Volume 96, Page(s) 111469

    Abstract: Study objective: The objective of this anatomical study was to investigate the distribution of a solution administered using the Clavipectoral Fascia Plane Block (CPB) technique in a series of cadaveric models with midshaft clavicular fractures. The ... ...

    Abstract Study objective: The objective of this anatomical study was to investigate the distribution of a solution administered using the Clavipectoral Fascia Plane Block (CPB) technique in a series of cadaveric models with midshaft clavicular fractures. The study aimed to address the knowledge gap regarding the impact of clavicular fractures on the distribution pattern of the CPB-administered solution.
    Design: Observational cadaveric study.
    Setting: The research was conducted in the laboratory setting of the University of Barcelona, adhering to the institution's ethical guidelines and standards.
    Patients: Five unembalmed human cadavers were used, generating ten clavicle samples.
    Interventions: A postmortem fracture was induced in the middle third of the clavicle using a blunt-edged hammer, simulating a midshaft clavicular fracture.
    Measurements: Anatomical dissection was performed in three layers: the superficial muscle plane, deep muscle plane, and clavicular periosteum plane. Dye staining with methylene blue was utilized to assess the distribution pattern.
    Main results: In the superficial muscular plane, methylene blue was observed in the deltoid (100%), pectoralis major (100%), sternocleidomastoid (SCM) (70%), and trapezius muscles (100%). Conversely, the deep muscular plane, including the subclavius muscle, pectoralis minor, and Clavipectoral Fascia (CPF), exhibited no staining. At the clavicular periosteum plane, methylene blue distributed predominantly to the antero-superior region (57.3%), with a minimal impact on the postero-inferior area (6.5%).
    Conclusions: The study reveals that the presence of a midshaft clavicular fracture does not significantly alter the diffusion pattern of the CPB-administered solution, maintaining a consistent distribution in both intact and fractured clavicle models.
    Language English
    Publishing date 2024-04-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2024.111469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2622: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: A Comprehensive Study on the Chemical Characterization and Neuroprotective Evaluation of Pracaxi Nuts Extracts Obtained by a Sustainable Approach.

    Mohammadnezhad, Pouya / Valdés, Alberto / Barrientos, Ruth E / Ibáñez, Elena / Block, Jane Mara / Cifuentes, Alejandro

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 20

    Abstract: ... The ... ...

    Abstract The Amazonian
    Language English
    Publishing date 2023-10-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12203879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Patrones de alimentación y crecimiento de los niños prematuros a los 3-4 años de vida.

    Valdés-Bécares, Ana / Lana Pérez, Alberto / Fernández Feito, Ana

    Nutricion hospitalaria

    2023  Volume 40, Issue 3, Page(s) 494–502

    Abstract: Introduction: Aim: to describe the feeding and growth patterns of preterm-born children at preschool age, considering feeding problems based on behaviours and skills, diet quality and parental feeding practices. Methods: a cross-sectional study was ... ...

    Title translation Feeding and growth patterns in preterm children at 3-4 years of age.
    Abstract Introduction: Aim: to describe the feeding and growth patterns of preterm-born children at preschool age, considering feeding problems based on behaviours and skills, diet quality and parental feeding practices. Methods: a cross-sectional study was performed on preterm children born in Asturias (Spain) in 2016 (n = 94). When preterm-born children reached 3-4 years of age their families were asked to complete the Behavioral Pediatrics Feeding Assessment Scale and a food frequency questionnaire to identify possible feeding problems and assess diet quality (KIDMED index), respectively. Self-reported anthropometric data were also collected to assess weight growth. Electronic health records were reviewed to gather gestational and neonatal clinical data. Results: feeding problems were found in 7.4 % of children and 20.2 % of parents. According to the KIDMED index, 25.5 % of children had a high-quality diet. Feeding problems were higher in children born before 32 weeks of gestation, and decreased in frequency as the gestational age increased (p = 0.030). No differences were found in parental feeding practices (p = 0.455) or diet quality according to gestational age (p = 0.399), but body weight at 3-4 years was lower in preterm-born children (p = 0.015). Conclusions: feeding patterns of preterm-born children were suitable at the age of 3-4 years, but diet quality was moderate to poor in the majority of children. Follow-up of very preterm children beyond 3-4 years of age becomes necessary as they displayed more feeding problems and lower body weight.
    MeSH term(s) Infant, Newborn ; Humans ; Child ; Child, Preschool ; Infant, Premature ; Cross-Sectional Studies ; Gestational Age ; Feeding Behavior ; Body Weight
    Language Spanish
    Publishing date 2023-06-21
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.04244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5078: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Tetraselmis chuii

    Cokdinleyen, Melis / Alvarez-Rivera, Gerardo / Tejera, Jose Luis González / Mendiola, José A / Valdés, Alberto / Kara, Huseyin / Ibáñez, Elena / Cifuentes, Alejandro

    International journal of molecular sciences

    2024  Volume 25, Issue 7

    Abstract: Tetraselmis ... ...

    Abstract Tetraselmis chuii
    MeSH term(s) Microalgae ; Reactive Oxygen Species ; Chlorophyta ; Cholinergic Antagonists ; Dietary Supplements ; Fatty Acids, Omega-3 ; Anti-Inflammatory Agents/pharmacology ; Solvents
    Chemical Substances Reactive Oxygen Species ; Cholinergic Antagonists ; Fatty Acids, Omega-3 ; Anti-Inflammatory Agents ; Solvents
    Language English
    Publishing date 2024-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25073897
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Metabolomic Characterization of the Antiproliferative Activity of Bioactive Compounds from Fruit By-Products Against Colon Cancer Cells.

    Alvarez-Rivera, Gerardo / Valdés, Alberto / Cifuentes, Alejandro

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2571, Page(s) 45–55

    Abstract: This methodological work demonstrates the potential of metabolomic approaches based on liquid chromatography coupled to high-resolution mass spectrometry (LC-ESI(+/-)-HRMS) to investigate the antiproliferative capacity of underexplored biomasses (e.g., ... ...

    Abstract This methodological work demonstrates the potential of metabolomic approaches based on liquid chromatography coupled to high-resolution mass spectrometry (LC-ESI(+/-)-HRMS) to investigate the antiproliferative capacity of underexplored biomasses (e.g., Passiflora mollissima seeds and Physalys peruviana calyx), by evaluating the molecular changes induced at the metabolite expression levels on HT-29 human colon cancer cells. This protocol describes in detail the optimal conditions to obtain bioactive extracts by pressurized liquid extraction (PLE), the experimental procedure to grow and treat HT-29 human colon cancer cells and CCD-18Co normal human colon fibroblasts with the target extracts, the metabolites extraction from the cytosolic fraction, and subsequent metabolomic fingerprinting. After treatment for 48 and 72 h, the viability of HT-29 colon cancer cells is markedly affected, and metabolites can be extracted for investigation. Following the proposed metabolomic data analysis and interpretation workflow, altered cellular redox homeostasis, as well as inactivation or dysfunction on other metabolic pathways, constitutes valuable biological information to understand the mechanisms underlying the antiproliferative effect.
    MeSH term(s) Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Fruit/metabolism ; Humans ; Metabolomics/methods ; Plant Extracts/chemistry ; Plant Extracts/pharmacology
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2022-09-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2699-3_5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Situs Inversus Totalis in Laparoscopic Sleeve Gastrectomy: A Case Report.

    Muñoz-Leija, Milton Alberto / Álvarez-Valdés, Guillermo / Rosales-Pérez, Gabriel

    Cureus

    2023  Volume 15, Issue 10, Page(s) e46539

    Abstract: Obesity is a pathology that is increasing in incidence globally and threatens public health. Currently, one of its most effective treatments is bariatric surgery, which has shown the best long-term results. One of the most frequently performed surgical ... ...

    Abstract Obesity is a pathology that is increasing in incidence globally and threatens public health. Currently, one of its most effective treatments is bariatric surgery, which has shown the best long-term results. One of the most frequently performed surgical procedures in this area is laparoscopic sleeve gastrectomy (LSG) or vertical sleeve. It is a restrictive technique that has had positive results in weight loss. Situs inversus totalis (SIT) is a strange condition with a low incidence in which thoracic and abdominal organs are on the opposite side of the already-known anatomic site, seen on a sagittal plane. The high demand for laparoscopic bariatric surgeries predisposes surgeons to find rare congenital anomalies in patients. Low prevalence and the anatomic mirror image condition may be challenging even for expert surgeons. Medical teams need to have knowledge of these cases and adjust the technique and procedure to complete the surgery without complications. We present a SIT case successfully treated with LSG in a male patient in Mexico.
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.46539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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