LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 478

Search options

  1. Article ; Online: SG-APSIC1062

    Chau Chain Yan / Giselle Li / Lim Min Wei

    Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3, Pp s7-s

    The role of active surveillance in the primary-care setting during a pandemic in Singapore

    2023  Volume 7

    Abstract: Objectives: In response to the COVID-19 pandemic, primary care swiftly transformed and re-established patient flow in clinics to red, orange, and green zones based on a set of screening criteria. To further manage the influx of suspected COVID-19 ... ...

    Abstract Objectives: In response to the COVID-19 pandemic, primary care swiftly transformed and re-established patient flow in clinics to red, orange, and green zones based on a set of screening criteria. To further manage the influx of suspected COVID-19 patients and their needs safely, a list of surveillance audit criteria was developed to ensure good infection control standards. Methods: The infection control team prepared the surveillance audit criteria based on recommended CDC/WHO guidelines for pandemic preparedness. These criteria were contextualized to the primary-care polyclinic setting. The surveillance audit criteria were grouped according to their category: screening, triage, early recognition and source control, inventory management of personal protective equipment (PPE), infection control measures in the red zone, precautionary measures during collection of nasopharyngeal swabs and environmental cleaning and disinfection for premises in the red, orange, and green zones, respectively. The infection control liaison nurses in each polyclinic were trained to use the checklist to ensure consistency in interpretation of the criteria. Results: Surveillance audits were conducted biweekly in the first 3 months then monthly once the compliance rate was steady at 90%–100% for all categories. The overall average compliance rate since commencing in March 2020 for all polyclinics was sustained at 90%–100%. Common findings included inappropriate use of PPE (eg, self-contamination during removal of gown or wrong sequence of doffing), inadequate ventilation, and inadequate cleaning processes. All findings were corrected immediately, and staff education was provided. Conclusions: Primary care plays an important role during a pandemic. It is essential that both patients and healthcare workers in the primary care setting are protected from infection risk during a pandemic. Having a good surveillance audit process helps ensure that primary care services can continue for the general population. Surveillance is an essential ...
    Keywords Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Non-Faradaic Promotion of Ethylene Hydrogenation under Oscillating Potentials.

    Lim, Chia Wei / Hülsey, Max J / Yan, Ning

    JACS Au

    2021  Volume 1, Issue 5, Page(s) 536–542

    Abstract: The acceleration of Faradaic reactions by oscillating electric potentials has emerged as a viable tool to enhance electrocatalysis, but the non-Faradaic dynamic promotion of thermal catalytic processes remains to be proven. Here, we present experimental ... ...

    Abstract The acceleration of Faradaic reactions by oscillating electric potentials has emerged as a viable tool to enhance electrocatalysis, but the non-Faradaic dynamic promotion of thermal catalytic processes remains to be proven. Here, we present experimental evidence showing that oscillating potentials are capable of enhancing the rate of ethylene hydrogenation despite no promotion effect being observed under static potentials. The non-Faradaic dynamic enhancement reaches up to 553% on a Pd/C electrode when cycling between -0.25 and 0.55 V
    Language English
    Publishing date 2021-04-14
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3704
    ISSN (online) 2691-3704
    DOI 10.1021/jacsau.1c00044
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Non-Faradaic Promotion of Ethylene Hydrogenation under Oscillating Potentials

    Chia Wei Lim / Max J. Hülsey / Ning Yan

    JACS Au, Vol 1, Iss 5, Pp 536-

    2021  Volume 542

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Novel drug candidates against antibiotic-resistant microorganisms: A review.

    Lim, Jing-Sheng / Chai, Yoke-Yen / Ser, Wei-Xin / Haeren, Aniqah Van / Lim, Yan-Hong / Raja, Tarshiiny / Foo, Jhi-Biau / Hamzah, Sharina / Sellappans, Renukha / Yow, Hui Yin

    Iranian journal of basic medical sciences

    2024  Volume 27, Issue 2, Page(s) 134–150

    Abstract: Antibiotic resistance is fast spreading globally, leading to treatment failures and adverse clinical outcomes. This review focuses on the resistance mechanisms of the top five threatening pathogens identified by the World Health Organization's global ... ...

    Abstract Antibiotic resistance is fast spreading globally, leading to treatment failures and adverse clinical outcomes. This review focuses on the resistance mechanisms of the top five threatening pathogens identified by the World Health Organization's global priority pathogens list: carbapenem-resistant
    Language English
    Publishing date 2024-01-04
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    DOI 10.22038/IJBMS.2023.71672.15593
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Is pre-stroke frailty as determined by the Clinical Frailty Scale version 2.0 associated with stroke outcomes?

    Ng, Chai Chen / Lim, Wan Chieh / Tan, Kit Mun / Wong, Kah Yan / Kanagarajah, Rajwin Raja / Singh, Harsukhpreet Singh A/L Kishore / Tan, Wei Guang

    Singapore medical journal

    2023  

    Language English
    Publishing date 2023-03-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 604319-7
    ISSN 2737-5935 ; 0037-5675
    ISSN (online) 2737-5935
    ISSN 0037-5675
    DOI 10.4103/singaporemedj.SMJ-2021-187
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 589: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Promoting heterogeneous catalysis beyond catalyst design.

    Hülsey, Max J / Lim, Chia Wei / Yan, Ning

    Chemical science

    2020  Volume 11, Issue 6, Page(s) 1456–1468

    Abstract: Despite the indisputable success of conventional approaches to manipulate the performance of heterogeneous catalysts by tuning the composition and structure of active sites, future research on catalysis engineering will likely go beyond the catalyst ... ...

    Abstract Despite the indisputable success of conventional approaches to manipulate the performance of heterogeneous catalysts by tuning the composition and structure of active sites, future research on catalysis engineering will likely go beyond the catalyst itself. Recently, several auxiliary promotion methods, either promoting the activity of reagents or enabling optimized adsorbate-catalyst interactions, have been proven as viable strategies to enhance catalytic reactions. Those auxiliary promotion methods range from electric/magnetic fields and electric potentials to mechanic stress, significantly altering the properties of reagent molecules and/or the surface characteristics of nanostructured catalysts. Apart from static enhancement effects, they in principle also allow for spatially and temporally variable modifications of catalyst surfaces. While some of those methods have been demonstrated, some are only theoretically predicted, opening exciting avenues for future experimental advances. Besides fundamental descriptions and comparisons of each activation method, in this perspective we plan to provide examples for the applications of those techniques for a variety of catalytic reactions as diverse as N
    Language English
    Publishing date 2020-01-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/c9sc05947d
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Subcutaneous fast-acting insulin analogues, alone or in combination with long-acting insulin, versus intravenous regular insulin infusion in patients with diabetic ketoacidosis: protocol for an updated systematic review and meta-analysis of randomised trials.

    Lim, Beng Leong / Lee, Wei Feng / Lee, Berlin / Chung, Yan Ee Lynette / Loo, Kee Vooi

    BMJ open

    2023  Volume 13, Issue 2, Page(s) e070131

    Abstract: Introduction: Diabetic ketoacidosis (DKA) is traditionally managed using intravenous regular insulin infusion (RII) in intensive care unit (ICU)/high dependency unit (HDU). Subcutaneous fast-acting insulin analogues (FAIAs) may help to manage DKA ... ...

    Abstract Introduction: Diabetic ketoacidosis (DKA) is traditionally managed using intravenous regular insulin infusion (RII) in intensive care unit (ICU)/high dependency unit (HDU). Subcutaneous fast-acting insulin analogues (FAIAs) may help to manage DKA outside ICU/HDU. Furthermore, combining subcutaneous long-acting insulin (LAI) with subcutaneous FAIAs may accelerate ketoacidosis resolution. The latest (2016) Cochrane review was inconclusive regarding subcutaneous FAIAs versus intravenous RII in DKA. It was limited by small sample sizes, unclear risk of bias (RoB) in primary trials and did not examine subcutaneous FAIAs with subcutaneous LAI versus intravenous RII in DKA. We report the protocol for an updated meta-analysis on the safety and benefits of subcutaneous FAIAs with/without subcutaneous LAI versus intravenous RII in DKA.
    Methods and analysis: We will search Medline, Embase, CINAHL and Cochrane Library, from inception until December 2022, without language restrictions, for randomised trials on subcutaneous FAIAs with/without subcutaneous LAI versus intravenous RII in DKA. We also search ClinicalTrials.gov, ClinicalTrialsRegister.eu and reference lists of included trials. Primary outcomes include all-cause in-hospital mortality, time to DKA resolution, in-hospital DKA recurrence and hospital readmission for DKA post-discharge. Secondary outcomes include resource utilisation and patient satisfaction. Safety outcomes include important complications of DKA and insulin. Reviewers will extract data, assess overall RoB and quality of evidence using Grading of Recommendations, Assessment, Development and Evaluation. We will assess statistical heterogeneity by visually inspecting forest plots and the I
    Ethics and dissemination: Ethics board approval is not required. Results will be disseminated through publication in a peer-reviewed journal.
    Prospero registration number: CRD42022369518.
    MeSH term(s) Humans ; Young Adult ; Adult ; Insulin/therapeutic use ; Insulin, Long-Acting/therapeutic use ; Hypoglycemic Agents/therapeutic use ; Diabetic Ketoacidosis/drug therapy ; Aftercare ; Injections, Subcutaneous ; Patient Discharge ; Diabetes Mellitus ; Meta-Analysis as Topic ; Systematic Reviews as Topic ; Randomized Controlled Trials as Topic
    Chemical Substances Insulin ; Insulin, Long-Acting ; Hypoglycemic Agents
    Language English
    Publishing date 2023-02-10
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-070131
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Multiplex Profiling of Biomarker and Drug Uptake in Single Cells Using Microfluidic Flow Cytometry and Mass Spectrometry.

    Zhang, Xuan / Wei, Xing / Wu, Cheng-Xin / Men, Xue / Wang, Jiao / Bai, Jun-Jie / Sun, Xiao-Yan / Wang, Yu / Yang, Ting / Lim, Chwee Teck / Chen, Ming-Li / Wang, Jian-Hua

    ACS nano

    2024  Volume 18, Issue 8, Page(s) 6612–6622

    Abstract: To perform multiplex profiling of single cells and eliminate the risk of potential sample loss caused by centrifugation, we developed a microfluidic flow cytometry and mass spectrometry system (μCytoMS) to evaluate the drug uptake and induced protein ... ...

    Abstract To perform multiplex profiling of single cells and eliminate the risk of potential sample loss caused by centrifugation, we developed a microfluidic flow cytometry and mass spectrometry system (μCytoMS) to evaluate the drug uptake and induced protein expression at the single cell level. It involves a microfluidic chip for the alignment and purification of single cells followed by detection with laser-induced fluorescence (LIF) and inductively coupled plasma mass spectrometry (ICP-MS). Biofunctionalized nanoprobes (BioNPs), conjugating ∼3000 6-FAM-Sgc8 aptamers on a single gold nanoparticle (AuNP) (
    MeSH term(s) Humans ; Microfluidics ; Flow Cytometry ; Gold ; Metal Nanoparticles ; Biomarkers ; Mass Spectrometry/methods ; Cell Adhesion Molecules ; Receptor Protein-Tyrosine Kinases
    Chemical Substances Gold (7440-57-5) ; Biomarkers ; PTK7 protein, human (EC 2.7.10.1) ; Cell Adhesion Molecules ; Receptor Protein-Tyrosine Kinases (EC 2.7.10.1)
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.3c12803
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: M-commerce adoption among youths in Malaysia: Dataset article.

    Lim, WeiLee / Sham, Rohana / Loi, Alexa Min-Wei / Shion, Enami / Wong, Bernard Yan-Bin

    Data in brief

    2022  Volume 42, Page(s) 108238

    Abstract: The covid-19 pandemic which took the world by storm changed our behaviour towards m-commerce with enforced movement restrictions across the world. This dataset documents the factors of consideration among Malaysian youths (age 15 to 24 years old) in ... ...

    Abstract The covid-19 pandemic which took the world by storm changed our behaviour towards m-commerce with enforced movement restrictions across the world. This dataset documents the factors of consideration among Malaysian youths (age 15 to 24 years old) in their intention to adopt m-commerce. Collected from October to November 2020, a total of 396 useable responses were finalized. The questionnaire consists of individual demographic variables and factors which influence the intention of youths to adopt m-commerce in Malaysia. The dataset of demographics and m-commerce related variables can be used to further explore the correlations and description of variables. The dataset is valuable for m-commerce service providers and future works of literature in understanding the behaviour of youths and hence increase the adoption rate of m-commerce among youths.
    Language English
    Publishing date 2022-05-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2022.108238
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Machine Learning Identifies a Signature of Nine Exosomal RNAs That Predicts Hepatocellular Carcinoma.

    Yap, Josephine Yu Yan / Goh, Laura Shih Hui / Lim, Ashley Jun Wei / Chong, Samuel S / Lim, Lee Jin / Lee, Caroline G

    Cancers

    2023  Volume 15, Issue 14

    Abstract: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Although alpha fetoprotein (AFP) remains a commonly used serological marker of HCC, the sensitivity and specificity of AFP in detecting HCC is often limited. ... ...

    Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Although alpha fetoprotein (AFP) remains a commonly used serological marker of HCC, the sensitivity and specificity of AFP in detecting HCC is often limited. Exosomal RNA has emerged as a promising diagnostic tool for various cancers, but its use in HCC detection has yet to be fully explored. Here, we employed Machine Learning on 114,602 exosomal RNAs to identify a signature that can predict HCC. The exosomal expression data of 118 HCC patients and 112 healthy individuals were stratified split into Training, Validation and Unseen Test datasets. Feature selection was then performed on the initial training dataset using permutation importance, and the predictive performance of the selected features were tested on the validation dataset using Support Vector Machine (SVM) Classifier. A minimum of nine features were identified to be predictive of HCC and these nine features were then evaluated across six different models in an unseen test set. These features, mainly in the immune, platelet/neutrophil and cytoskeletal pathways, exhibited good predictive performance with ROC-AUC from 0.79-0.88 in the unseen test set. Hence, these nine exosomal RNAs have potential to be clinically useful minimally invasive biomarkers for HCC.
    Language English
    Publishing date 2023-07-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15143749
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top