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  1. Article ; Online: An atypical case of phosphoglycerate kinase deficiency with a novel PGK1 variant.

    Zhou, Xizhong / Liu, Qiuli / Huang, Mingwei

    Seizure

    2024  Volume 117, Page(s) 161–163

    MeSH term(s) Humans ; Phosphoglycerate Kinase/genetics ; Phosphoglycerate Kinase/deficiency ; Male ; Joint Instability/genetics ; Female ; Spinal Diseases/genetics ; Metabolism, Inborn Errors ; Genetic Diseases, X-Linked
    Chemical Substances Phosphoglycerate Kinase (EC 2.7.2.3) ; PGK1 protein, human (EC 2.7.2.3)
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Case Reports ; Letter ; Journal Article
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2024.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3573: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Self-Adaptive Rapid Thermal Conductive Fabrics Based on Hygroscopic Shrinkage Response for Personal Cooling and Drying.

    Liu, Hongkun / Xiao, Yanan / Shen, Yang / Liu, Qiuli / Hou, Jiazi

    ACS applied materials & interfaces

    2024  Volume 16, Issue 6, Page(s) 7917–7926

    Abstract: Advanced fabrics with thermal wet management capability as low energy consumption media contribute to personal cooling and drying. Nevertheless, it remains a great challenge to obtain intelligent fabrics with adjustable thermal conductivity (TC) capable ... ...

    Abstract Advanced fabrics with thermal wet management capability as low energy consumption media contribute to personal cooling and drying. Nevertheless, it remains a great challenge to obtain intelligent fabrics with adjustable thermal conductivity (TC) capable of bridging the supply and demand between human body temperature and self-adaptive thermal conduction. Herein, we report hygroscopic-shrinkage nanofiber-based fabrics with excellent moisture sensitivity and significant volume shrinkage, which benefits the construction of high-density thermal conductive pathways by absorbing sweat, with a maximum sweat absorption rate reaching up to 1781%. The TC of the shrunken fabric is significantly increased from the initial 0.102 to 0.731 W·m
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c18476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Causal Association Between Diabetes, Body Mass Index and Lichen Sclerosus: A Bidirectional Two-Sample Mendelian Randomization Analysis.

    Liu, Lin / Zhang, Qiuli / Chang, Jianmin / Yang, Kun

    Clinical, cosmetic and investigational dermatology

    2024  Volume 17, Page(s) 931–940

    Abstract: Background: Previous observational studies have found that lichen sclerosus (LS) is associated with metabolic statuses, such as diabetes mellitus (DM) and body mass index (BMI). However, there are also some studies showing that LS is not related to DM ... ...

    Abstract Background: Previous observational studies have found that lichen sclerosus (LS) is associated with metabolic statuses, such as diabetes mellitus (DM) and body mass index (BMI). However, there are also some studies showing that LS is not related to DM and BMI. The mechanism behind observational results is still unclear. Therefore, the causality of this relationship remains unknown. In this study, a bidirectional two-sample Mendelian randomization (MR) was conducted to investigate the correlation between DM, BMI, and LS.
    Methods: The instrumental variables related to DM (including type 1 and type 2 diabetes), and BMI were identified from genome-wide association studies (GWAS) and a GWAS meta-analysis. The GWAS data for LS was from obtained the eighth edition of the FinnGen biological database released in 2022. Inverse variance weighted (IVW), weighted median, and MR-Egger methods were used to conduct a bidirectional two-sample MR analysis. Thereafter, the heterogeneity and horizontal pleiotropy were examined to determine whether the results were affected by a single-nucleotide polymorphism (SNP).
    Results: We found a lack of evidence for the causal association of DM, and BMI on LS in inverse variance weighted (type 1 diabetes, OR=0.97, 95% CI=0.91-1.04, p=0.429; type 2 diabetes, OR=0.91, 95% CI=0.82-1.00, p=0.0511; BMI, OR=0.92, 95% CI=0.73-1.15, p=0.4554). In the other direction, the results also showed that LS had no significant causal effect on DM and BMI.
    Conclusion: This MR analysis demonstrated no significant causal relationship between DM and BMI with LS in both directions, which contradicts previous observational studies reporting a positive association. Potential confounding factors may contribute to previously observed associations, and further research is necessary.
    Language English
    Publishing date 2024-04-26
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S450399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Study on the regulation mechanism of effective glass transition temperature on the crystallization of crystalline solid dispersion.

    Zhang, Yong / Yan, Qiuli / Liu, Yao / Hu, Chunhui

    Drug delivery and translational research

    2023  Volume 13, Issue 10, Page(s) 2677–2689

    Abstract: The focus of this investigation was to determine the mechanism of effective glass transition temperature ( ... ...

    Abstract The focus of this investigation was to determine the mechanism of effective glass transition temperature (T
    MeSH term(s) Crystallization ; Transition Temperature ; Temperature ; Kinetics ; Poloxamer/chemistry ; Solubility
    Chemical Substances Poloxamer (106392-12-5)
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2590155-2
    ISSN 2190-3948 ; 2190-393X
    ISSN (online) 2190-3948
    ISSN 2190-393X
    DOI 10.1007/s13346-023-01348-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Comparison of remimazolam and propofol combined with low dose esketamine for pediatric same-day painless bidirectional endoscopy: a randomized, controlled clinical trial.

    Chu, Tiantian / Zhou, Siqi / Wan, Yingfeng / Liu, Qiuli / Xin, Yueyang / Tian, Zhang / Yan, Tianqing / Xu, Aijun

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1298409

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1298409
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  6. Article ; Online: Polychlorinated biphenyls exposure and type 2 diabetes: Molecular mechanism that causes insulin resistance and islet damage.

    Shan, Qiuli / Liu, Jingyu / Qu, Fan / Chen, Anhui / He, Wenxing

    Environmental toxicology

    2024  Volume 39, Issue 4, Page(s) 2466–2476

    Abstract: Polychlorinated biphenyls (PCBs) are typical persistent organic pollutants that have been associated with type 2 diabetes (T2DM) in cohort studies. This review aims to comprehensively assess the molecular mechanisms of PCBs-induced T2DM. Recent progress ... ...

    Abstract Polychlorinated biphenyls (PCBs) are typical persistent organic pollutants that have been associated with type 2 diabetes (T2DM) in cohort studies. This review aims to comprehensively assess the molecular mechanisms of PCBs-induced T2DM. Recent progress has been made in the research of PCBs in liver tissue, adipose tissue, and other tissues. By influencing the function of nuclear receptors, such as the aryl hydrocarbon receptor (AhR), pregnancy X receptor (PXR), and peroxisome proliferator activated receptor γ (PPARγ), as well as the inflammatory response, PCBs disrupt the balance of hepatic glucose and lipid metabolism. This is associated with insulin resistance (IR) in the target organ of insulin. Through androgen receptor (AR), estrogen receptor α/β (ERα/β), and pancreato-duodenal-homeobox gene-1 (PDX-1), PCBs affect the secretion of insulin and increase blood glucose. Thus, this review is a discussion on the relationship between PCBs exposure and the pathogenesis of T2DM. It is hoped to provide basic concepts for diabetes research and disease treatment.
    MeSH term(s) Humans ; Polychlorinated Biphenyls/toxicity ; Insulin Resistance ; Diabetes Mellitus, Type 2/chemically induced ; Diabetes Mellitus, Type 2/pathology ; Liver/metabolism ; Insulins ; Receptors, Aryl Hydrocarbon
    Chemical Substances Polychlorinated Biphenyls (DFC2HB4I0K) ; Insulins ; Receptors, Aryl Hydrocarbon
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1463449-1
    ISSN 1522-7278 ; 1520-4081
    ISSN (online) 1522-7278
    ISSN 1520-4081
    DOI 10.1002/tox.24094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2676: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Emerging role of the RNA-editing enzyme ADAR1 in stem cell fate and function.

    Lu, Di / Lu, Jianxi / Liu, Qiuli / Zhang, Qi

    Biomarker research

    2023  Volume 11, Issue 1, Page(s) 61

    Abstract: Stem cells are critical for organism development and the maintenance of tissue homeostasis. Recent studies focusing on RNA editing have indicated how this mark controls stem cell fate and function in both normal and malignant states. RNA editing is ... ...

    Abstract Stem cells are critical for organism development and the maintenance of tissue homeostasis. Recent studies focusing on RNA editing have indicated how this mark controls stem cell fate and function in both normal and malignant states. RNA editing is mainly mediated by adenosine deaminase acting on RNA 1 (ADAR1). The RNA editing enzyme ADAR1 converts adenosine in a double-stranded RNA (dsRNA) substrate into inosine. ADAR1 is a multifunctional protein that regulate physiological processes including embryonic development, cell differentiation, and immune regulation, and even apply to the development of gene editing technologies. In this review, we summarize the structure and function of ADAR1 with a focus on how it can mediate distinct functions in stem cell self-renewal and differentiation. Targeting ADAR1 has emerged as a potential novel therapeutic strategy in both normal and dysregulated stem cell contexts.
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2699926-2
    ISSN 2050-7771
    ISSN 2050-7771
    DOI 10.1186/s40364-023-00503-7
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  8. Article ; Online: Progress of residual neuromuscular blockade after general anesthesia in elderly patients

    LIU Qiuli / JIANG Lai / WENG Xiaojian

    Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 1, Pp 108-

    2023  Volume 113

    Abstract: Muscle relaxation induced by muscle relaxants is one of the important conditions for endotracheal intubation and fixation, but sometimes muscle functions recover incompletely after operations, which is called postoperative residual neuromuscular block ( ... ...

    Abstract Muscle relaxation induced by muscle relaxants is one of the important conditions for endotracheal intubation and fixation, but sometimes muscle functions recover incompletely after operations, which is called postoperative residual neuromuscular block (PRNB). It can cause a series of serious postoperative complications and even death. Hence, it is essential to prevent and treat PRNB in the early stage during anesthesia implementation. With the rapid development of surgical technology and the gradual extension of the life span of the population, the number of operations for elderly patients is gradually increasing. Meanwhile, due to the physiological and pathological changes of the elderly and the combined underlying diseases, the elderly are more likely to suffer from PRNB in different degrees after surgery, which seriously damages the prognosis of elderly patients and increases the loss of medical resources. In these years, the successful application of short-acting muscle relaxants, new antagonists (such as sugammadex), and multi-mode neuromuscular monitoring devices in clinical practice have greatly reduced the incidence of PRNB in elderly patients. Furthermore, the basic researches which mainly based on the neuromuscular junction structure and the pharmacokinetic and pharmacodynamic studies of the elderly provide a new theoretical basis for reducing the harm of PRNB to elderly patients. This paper reviews the research progress of the mechanism, adverse events and clinical interventions of PRNB in elderly patients after general anesthesia surgeries to provide reference for muscle relaxation management and postoperative antagonism in these people.
    Keywords the elderly ; postoperative residual neuromuscular block (prnb) ; neuromuscular blocking agent ; muscle relaxant antagonism ; Medicine ; R
    Subject code 796
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Transcriptome Analysis to Identify Responsive Genes under Sublethal Concentration of Bifenazate in the Diamondback Moth,

    Hou, Qiuli / Zhang, Hanqiao / Zhu, Jiani / Liu, Fang

    International journal of molecular sciences

    2022  Volume 23, Issue 21

    Abstract: Bifenazate is a novel acaricide that has been widely used to control spider mites. Interestingly, we found bifenazate had a biological activity against the diamondback moth ( ...

    Abstract Bifenazate is a novel acaricide that has been widely used to control spider mites. Interestingly, we found bifenazate had a biological activity against the diamondback moth (
    MeSH term(s) Animals ; Moths/genetics ; Moths/metabolism ; Gene Expression Profiling ; Carbamates ; Hydrazines/metabolism ; Transcriptome ; Larva/genetics
    Chemical Substances bifenazate (24Z9QW0505) ; Carbamates ; Hydrazines
    Language English
    Publishing date 2022-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232113173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Inhibitory Mechanisms of

    Ouyang, Qiuli / Shi, Shiwei / Liu, Yangmei / Yang, Yanqin / Zhang, Yonghua / Yuan, Xingxing / Tao, Nengguo / Li, Lu

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 9

    Abstract: Geotrichum ... ...

    Abstract Geotrichum citri
    Language English
    Publishing date 2023-09-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9090930
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