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  1. Article: A Narrative Review of Current and Emerging Trends in the Treatment of Alcohol Use Disorder.

    Celik, Muhammet / Gold, Mark S / Fuehrlein, Brian

    Brain sciences

    2024  Volume 14, Issue 3

    Abstract: ... undertreated, marked by a scarcity of approved medications. This paper explores the current treatment landscape ...

    Abstract Alcohol use disorder (AUD) is a significant contributor to morbidity and mortality in the United States. It contributes to over 140,000 annual deaths, to over 200 related diseases and health conditions globally, and accounts for 5.1% of the global disease burden. Despite its substantial impact, AUD remains undertreated, marked by a scarcity of approved medications. This paper explores the current treatment landscape and novel strategies for both alcohol withdrawal syndrome and AUD. Promising results, including the use of psychedelics alongside psychotherapy, noninvasive neural-circuit-based interventions, phosphodiesterase-4 inhibitors, and GLP-1 receptor agonists, have emerged from recent studies. While these advancements show potential, further research is crucial for a comprehensive understanding of their effectiveness. The clear shortage of approved medications and other treatment modalities underscores the pressing need for ongoing research.
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14030294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Food and addiction

    Brownell, Kelly D. / Gold, Mark S.

    a comprehensive handbook

    2012  

    Author's details ed. by Kelly D. Brownell ; Mark S. Gold
    Keywords Essstörung
    Subject Essgewohnheit ; Essstörungen
    Language English
    Size XXIII, 462 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017414201
    ISBN 978-0-19-973816-8 ; 0-19-973816-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 4053 order for loan Magazin

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  3. Article: The Role of Alcohol, Drugs, and Deaths of Despair in the U.S.'s Falling Life Expectancy.

    Gold, Mark S

    Missouri medicine

    2020  Volume 117, Issue 2, Page(s) 99–101

    MeSH term(s) Adult ; Cause of Death ; Drug Overdose/mortality ; Female ; Humans ; Life Expectancy/trends ; Liver Diseases, Alcoholic/mortality ; Male ; Middle Aged ; Sex Factors ; United States
    Language English
    Publishing date 2020-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 427362-x
    ISSN 0026-6620
    ISSN 0026-6620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Chronic Methylphenidate Effects on Brain Gene Expression: An Exploratory Review.

    Klein, Shannon Rae / Blum, Kenneth / Gold, Mark S / Thanos, Panayotis K

    Psychology research and behavior management

    2024  Volume 17, Page(s) 577–592

    Abstract: Methylphenidate (MP) is a psychostimulant commonly prescribed for individuals with attention deficit hyperactivity disorder (ADHD) but it is also taken with and without a prescription for performance enhancement. Prior research has characterized the ... ...

    Abstract Methylphenidate (MP) is a psychostimulant commonly prescribed for individuals with attention deficit hyperactivity disorder (ADHD) but it is also taken with and without a prescription for performance enhancement. Prior research has characterized the effects of MP on behavior, cognition, and neurochemistry. This exploratory review covers the uses of MP and examined the effects of MP on gene expression in the brain following exposure. Overall, MP causes a wide-spread potentiation of genes, in a region-specific manner; consequently, inducing neuronal alterations, such as synaptic plasticity and transmission, resulting in observed behaviors and affects. Monoamine neurotransmitters and post-synaptic density protein genes generally had a potentiating effect in gene expression after exposure to MP.
    Language English
    Publishing date 2024-02-15
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2495093-2
    ISSN 1179-1578
    ISSN 1179-1578
    DOI 10.2147/PRBM.S445719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Addictive disorders in medical populations

    Miller, Norman S. / Gold, Mark S.

    2010  

    Author's details ed. Norman S. Miller ; Mark S. Gold
    Keywords Substance-Related Disorders / diagnosis ; Substance-Related Disorders / therapy
    Language English
    Size XII, 629 S. : Ill., graph. Darst., 25 cm
    Publisher Wiley-Blackwell
    Publishing place Chichester u.a.
    Publishing country Great Britain
    Document type Book
    Note Formerly CIP Uk. - Includes bibliographical references and index
    HBZ-ID HT016571916
    ISBN 978-0-470-74033-0 ; 0-470-74033-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 5502 order for loan Magazin

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  7. Book: Eating disorders, overeating, and pathological attachment to food

    Gold, Mark S.

    independent or addictive disorders?

    2004  

    Author's details Mark S. Gold, ed
    Keywords Eating Disorders / etiology ; Behavior, Addictive ; Essstörung ; Essgewohnheit ; Sucht
    Subject Suchtkrankheit ; Suchterkrankung ; Essverhalten ; Speisegewohnheit ; Essgewohnheit ; Essstörungen
    Language English
    Size 122 S. : Ill., graph. Darst.
    Publisher Haworth Medical Press
    Publishing place Binghamton, NY
    Publishing country United States
    Document type Book
    Note Aus: Journal of addictive diseases ; 23,3
    HBZ-ID HT014122902
    ISBN 0-7890-2600-7 ; 0-7890-2593-0 ; 978-0-7890-2600-2 ; 978-0-7890-2593-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 4506 order for loan Magazin

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  8. Article: Treatments for Cannabis Use Disorder across the Lifespan: A Systematic Review.

    Ghafouri, Mohammad / Correa da Costa, Sabrina / Zare Dehnavi, Ali / Gold, Mark S / Rummans, Teresa A

    Brain sciences

    2024  Volume 14, Issue 3

    Abstract: Cannabis use disorder (CUD) is a growing public health concern, with rising prevalence and significant impact on individuals across age groups. This systematic review examines 24 studies investigating pharmacological and non-pharmacological interventions ...

    Abstract Cannabis use disorder (CUD) is a growing public health concern, with rising prevalence and significant impact on individuals across age groups. This systematic review examines 24 studies investigating pharmacological and non-pharmacological interventions for CUD among adolescents (up to 17), young adults (18-24), and older adults (25-65). Database searches were conducted for randomized controlled trials of CUD interventions reporting outcomes such as cannabis use, abstinence, withdrawal symptoms, and treatment retention. For adolescents, interventions such as contingent rewards and family engagement have shown promise, while young adults benefit from technology-based platforms and peer support. In older adults, pharmacological adjuncts combined with counseling have shown promise in enhancing treatment outcomes. However, optimal treatment combinations remain uncertain, highlighting the need for further research. Addressing CUD requires tailored interventions that acknowledge developmental stages and challenges across the lifespan. Although promising interventions exist, further comparative effectiveness research is needed to delineate the most efficacious approaches.
    Language English
    Publishing date 2024-02-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14030227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Opioid use disorder: current trends and potential treatments.

    Lee, Yu Kyung / Gold, Mark S / Blum, Kenneth / Thanos, Panayotis K / Hanna, Colin / Fuehrlein, Brian S

    Frontiers in public health

    2024  Volume 11, Page(s) 1274719

    Abstract: Opioid use disorder (OUD) is a major public health threat, contributing to morbidity and mortality from addiction, overdose, and related medical conditions. Despite our increasing knowledge about the pathophysiology and existing medical treatments of OUD, ...

    Abstract Opioid use disorder (OUD) is a major public health threat, contributing to morbidity and mortality from addiction, overdose, and related medical conditions. Despite our increasing knowledge about the pathophysiology and existing medical treatments of OUD, it has remained a relapsing and remitting disorder for decades, with rising deaths from overdoses, rather than declining. The COVID-19 pandemic has accelerated the increase in overall substance use and interrupted access to treatment. If increased naloxone access, more buprenorphine prescribers, greater access to treatment, enhanced reimbursement, less stigma and various harm reduction strategies were effective for OUD, overdose deaths would not be at an all-time high. Different prevention and treatment approaches are needed to reverse the concerning trend in OUD. This article will review the recent trends and limitations on existing medications for OUD and briefly review novel approaches to treatment that have the potential to be more durable and effective than existing medications. The focus will be on promising interventional treatments, psychedelics, neuroimmune, neutraceutical, and electromagnetic therapies. At different phases of investigation and FDA approval, these novel approaches have the potential to not just reduce overdoses and deaths, but attenuate OUD, as well as address existing comorbid disorders.
    MeSH term(s) Humans ; Pandemics ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Buprenorphine/therapeutic use ; Naloxone/therapeutic use ; Drug Overdose/drug therapy ; Drug Overdose/prevention & control
    Chemical Substances Buprenorphine (40D3SCR4GZ) ; Naloxone (36B82AMQ7N)
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1274719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Efficacy and Safety of LetibotulinumtoxinA in the Treatment of Moderate and Severe Glabellar Lines in Females 35 to 50 Years of Age: Post Hoc Analyses of the Phase 3 Clinical Study Data.

    Gold, Michael / Taylor, Susan / Mueller, Daniel S / Adelglass, Jeffrey / Kaufman-Janette, Joely / Cox, Sue E / Cecerle, Michael / Frank, Konstantin / Nestor, Mark

    Aesthetic surgery journal. Open forum

    2024  Volume 6, Page(s) ojae010

    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ISSN 2631-4797
    ISSN (online) 2631-4797
    DOI 10.1093/asjof/ojae010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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