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  1. Book ; Online ; E-Book: The therapist's guide to psychopharmacology

    Patterson, JoEllen / Griffith, James L. / Edwards, Todd M.

    working with patients, families and physicians to optimize care

    2021  

    Author's details JoEllen Patterson, James L. Griffith, Todd M. Edwards
    Keywords Mental Disorders / drug therapy ; Psychopharmacology / methods ; Psychotropic Drugs / therapeutic use ; Referral and Consultation | ; Psychopharmacology ; Psychotropic drugs ; Psychotherapy
    Subject code 615.78
    Language English
    Size 1 Online-Ressource (xx, 308 Seiten), 23 cm
    Edition Third edition
    Publisher Guilford Press
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021042676
    ISBN 9781462547968 ; 9781462547678 ; 9781462547661 ; 1462547966 ; 1462547672 ; 1462547664
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Inactivation of SARS-CoV-2 on surfaces and in solution with Virusend (TX-10), a novel disinfectant.

    Anderson, Enyia R / Hughes, Grant L / Patterson, Edward I

    Access microbiology

    2021  Volume 3, Issue 4, Page(s) 228

    Abstract: Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means ... ...

    Abstract Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means indirect contact transmission can occur and there is an opportunity to reduce transmission using effective disinfectants in public and communal spaces. Virusend (TX-10), a novel disinfectant, has been developed as a highly effective disinfectant against a range of microbial agents. Here we investigate the ability of Virusend to inactivate SARS-CoV-2. Using surface and solution inactivation assays, we show that Virusend is able to reduce SARS-CoV-2 viral titre by 4 log
    Language English
    Publishing date 2021-04-26
    Publishing country England
    Document type Journal Article
    ISSN 2516-8290
    ISSN (online) 2516-8290
    DOI 10.1099/acmi.0.000228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Knockdown resistance allele L1014F introduced by CRISPR/Cas9 is not associated with altered vector competence of Anopheles gambiae for o'nyong nyong virus.

    Kay, Grant A / Patterson, Edward I / Hughes, Grant L / Lord, Jennifer S / Reimer, Lisa J

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0288994

    Abstract: Knockdown resistance (kdr) alleles conferring resistance to pyrethroid insecticides are widespread amongst vector populations. Previous research has suggested that these alleles are associated with changes in the vector competence of mosquitoes for ... ...

    Abstract Knockdown resistance (kdr) alleles conferring resistance to pyrethroid insecticides are widespread amongst vector populations. Previous research has suggested that these alleles are associated with changes in the vector competence of mosquitoes for arboviruses and Plasmodium, however non-target genetic differences between mosquito strains may have had a confounding effect. Here, to minimise genetic differences, the laboratory Anopheles gambiae Kisumu strain was compared to a CRISPR/Cas9 homozygous kdr L1014F mutant Kisumu-kdr line in order to examine associations with vector competence for o'nyong nyong virus (ONNV). Mosquitoes were infected using either blood feeds or intrathoracic microinjections. There were no significant differences in the prevalence of virus in mosquito body parts between kdr mutant and wildtype lines from either oral or intrathoracic injection routes. The ONNV titre was significantly higher in the legs of the wildtype strain at 7dpi following intrathoracic microinjection, but no other significant differences in viral titre were detected. ONNV was not detected in the saliva of mosquitoes from either strain. Our findings from per os infections suggest that the kdr L1014F allele is not associated with altered infection prevalence for ONNV, a key component of vector competence.
    MeSH term(s) Animals ; O'nyong-nyong Virus ; Anopheles/genetics ; Alleles ; CRISPR-Cas Systems/genetics ; Mosquito Vectors/genetics ; Insecticide Resistance/genetics ; Insecticides
    Chemical Substances Insecticides
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0288994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Methods of SARS-CoV-2 Inactivation.

    Anderson, Enyia R / Prince, Tessa / Turtle, Lance / Hughes, Grant L / Patterson, Edward I

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2452, Page(s) 465–473

    Abstract: Inactivation methods allow for hazard group 3 (HG3) pathogens to be disposed of and used safely in downstream experiments and assays to be carried out at lower containment levels. Commonly used viral inactivation methods include heat inactivation, ... ...

    Abstract Inactivation methods allow for hazard group 3 (HG3) pathogens to be disposed of and used safely in downstream experiments and assays to be carried out at lower containment levels. Commonly used viral inactivation methods include heat inactivation, fixation methods, ultraviolet (UV) light and detergent inactivation. Here we describe known methods used to inactivate SARS-CoV-2 for safe downstream biological assays.
    MeSH term(s) Animals ; COVID-19 ; Chlorocebus aethiops ; SARS-CoV-2 ; Ultraviolet Rays ; Vero Cells ; Virus Inactivation
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2111-0_25
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Inactivation of SARS-CoV-2 on surfaces and in solution with Virusend (TX-10), a novel disinfectant.

    Anderson, Enyia R / Hughes, Grant L / Patterson, Edward I

    bioRxiv : the preprint server for biology

    2020  

    Abstract: Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means ... ...

    Abstract Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means indirect contact transmission can occur and so there is an opportunity to reduce transmission using effective disinfectants in public and communal spaces. Virusend (TX-10), a novel disinfectant, has been developed as a highly effective disinfectant against a range of microbial agents. Here we investigate the ability of Virusend (TX-10) to inactivation SARS-CoV-2. Using surface and solution inactivation assays, we show that Virusend (TX-10) is able to reduce SARS-CoV-2 viral titre by 4log
    Language English
    Publishing date 2020-11-27
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2020.11.25.394288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum: A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons.

    Ma, Qicheng / Srivastav, Satyam P / Gamez, Stephanie / Dayama, Gargi / Feitosa-Suntheimer, Fabiana / Patterson, Edward I / Johnson, Rebecca M / Matson, Erik M / Gold, Alexander S / Brackney, Douglas E / Connor, John H / Colpitts, Tonya M / Hughes, Grant L / Rasgon, Jason L / Nolan, Tony / Akbari, Omar S / Lau, Nelson C

    Genome research

    2024  Volume 34, Issue 1, Page(s) 160

    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 1284872-4
    ISSN 1549-5469 ; 1088-9051 ; 1054-9803
    ISSN (online) 1549-5469
    ISSN 1088-9051 ; 1054-9803
    DOI 10.1101/gr.278898.123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: SARS-CoV-2 Infections in Animals: Reservoirs for Reverse Zoonosis and Models for Study.

    Prince, Tessa / Smith, Shirley L / Radford, Alan D / Solomon, Tom / Hughes, Grant L / Patterson, Edward I

    Viruses

    2021  Volume 13, Issue 3

    Abstract: The recent SARS-CoV-2 pandemic has brought many questions over the origin of the virus, the threat it poses to animals both in the wild and captivity, and the risks of a permanent viral reservoir developing in animals. Animal experiments have shown that ... ...

    Abstract The recent SARS-CoV-2 pandemic has brought many questions over the origin of the virus, the threat it poses to animals both in the wild and captivity, and the risks of a permanent viral reservoir developing in animals. Animal experiments have shown that a variety of animals can become infected with the virus. While coronaviruses have been known to infect animals for decades, the true intermediate host of the virus has not been identified, with no cases of SARS-CoV-2 in wild animals. The screening of wild, farmed, and domesticated animals is necessary to help us understand the virus and its origins and prevent future outbreaks of both COVID-19 and other diseases. There is intriguing evidence that farmed mink infections (acquired from humans) have led to infection of other farm workers in turn, with a recent outbreak of a mink variant in humans in Denmark. A thorough examination of the current knowledge and evidence of the ability of SARS-CoV-2 to infect different animal species is therefore vital to evaluate the threat of animal to human transmission and reverse zoonosis.
    MeSH term(s) Animals ; Animals, Wild/virology ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/veterinary ; COVID-19/virology ; Disease Reservoirs/virology ; Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology ; Zoonoses/epidemiology ; Zoonoses/transmission ; Zoonoses/virology
    Language English
    Publishing date 2021-03-17
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13030494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Considerations and clinical management of infections in sarcoidosis.

    Chen, Edward S / Patterson, Karen C

    Current opinion in pulmonary medicine

    2023  Volume 29, Issue 5, Page(s) 525–531

    Abstract: Purpose of review: To summarize data from recent reports about risks and outcomes of the infections most often reported in patients with sarcoidosis.: Recent findings: Rates of fungal infections and other severe infections are higher in patients with ...

    Abstract Purpose of review: To summarize data from recent reports about risks and outcomes of the infections most often reported in patients with sarcoidosis.
    Recent findings: Rates of fungal infections and other severe infections are higher in patients with sarcoidosis compared to controls. Immunosuppression further increases the risk for an infection requiring hospitalization. In contrast, outcomes of coronavirus disease 2019 (COVID-19) are not worse unless lung impairment or other comorbidities are present.
    Summary: Tuberculosis, fungal infections, and other severe infections requiring hospital admission are, fortunately, relatively rare in patients with sarcoidosis who live in nonendemic regions. However, ongoing vigilance is required when the course of sarcoidosis is atypical or inexplicably progressive, as costs are high when these infections are missed. In contrast, COVID-19 and other respiratory viral illnesses are common, including among patients with sarcoidosis. When organ impairment is minimal, an underlying diagnosis of sarcoidosis does not appear to increase the risk of severe COVID-19, but patients may have higher risks due to comorbidities, which are important factors to address in routine sarcoidosis care. The burden from respiratory viral events, including impacts on quality of life and life functionality including work capacity, is unknown and is important to measure.
    MeSH term(s) Humans ; COVID-19/complications ; COVID-19/epidemiology ; Quality of Life ; Sarcoidosis/epidemiology ; Sarcoidosis/diagnosis ; Comorbidity ; Mycoses
    Language English
    Publishing date 2023-07-12
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000000986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Inactivation of SARS-CoV-2 on surfaces and in solution with Virusend (TX-10), a novel disinfectant

    Anderson, Enyia R / Hughes, Grant L / Patterson, Edward I

    bioRxiv

    Abstract: Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means ... ...

    Abstract Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means indirect contact transmission can occur and so there is an opportunity to reduce transmission using effective disinfectants in public and communal spaces. Virusend (TX-10), a novel disinfectant, has been developed as a highly effective disinfectant against a range of microbial agents. Here we investigate the ability of Virusend (TX-10) to inactivation SARS-CoV-2. Using surface and solution inactivation assays, we show that Virusend (TX-10) is able to reduce SARS-CoV-2 viral titre by 4log10 PFU/mL within 1 minute of contact. Ensuring disinfectants are highly effective against SARS-CoV-2 is important in eliminating environmental sources of the virus to control the COVID-19 pandemic.
    Keywords covid19
    Language English
    Publishing date 2020-11-27
    Publisher Cold Spring Harbor Laboratory
    Document type Article ; Online
    DOI 10.1101/2020.11.25.394288
    Database COVID19

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  10. Article ; Online: Vertical and Horizontal Transmission of Cell Fusing Agent Virus in Aedes aegypti.

    Logan, Rhiannon A E / Quek, Shannon / Muthoni, Joseph N / von Eicken, Anneliese / Brettell, Laura E / Anderson, Enyia R / Villena, Marcus E N / Hegde, Shivanand / Patterson, Grace T / Heinz, Eva / Hughes, Grant L / Patterson, Edward I

    Applied and environmental microbiology

    2022  Volume 88, Issue 18, Page(s) e0106222

    Abstract: Cell fusing agent virus (CFAV) is an insect-specific flavivirus (ISF) found in Aedes aegypti mosquitoes. ISFs have demonstrated the ability to modulate the infection or transmission of arboviruses such as dengue, West Nile, and Zika viruses. It is ... ...

    Abstract Cell fusing agent virus (CFAV) is an insect-specific flavivirus (ISF) found in Aedes aegypti mosquitoes. ISFs have demonstrated the ability to modulate the infection or transmission of arboviruses such as dengue, West Nile, and Zika viruses. It is thought that vertical transmission is the main route for ISF maintenance in nature. This has been observed with CFAV, but there is evidence of horizontal and venereal transmission in other ISFs. Understanding the route of transmission can inform strategies to spread ISFs to vector populations as a method of controlling pathogenic arboviruses. We crossed individually reared male and female mosquitoes from both a naturally occurring CFAV-positive Ae. aegypti colony and its negative counterpart to provide information on maternal, paternal, and horizontal transmission. RT-PCR was used to detect CFAV in individual female pupal exuviae and was 89% sensitive, but only 42% in male pupal exuviae. This is a possible way to screen individuals for infection without destroying the adults. Female-to-male horizontal transmission was not observed during this study. However, there was a 31% transmission rate from mating pairs of CFAV-positive males to negative female mosquitoes. Maternal vertical transmission was observed with a filial infection rate of 93%. The rate of paternal transmission was 85% when the female remained negative, 61% when the female acquired CFAV horizontally, and 76% overall. Maternal and paternal transmission of CFAV could allow the introduction of this virus into wild Ae. aegypti populations through male or female mosquito releases, and thus provides a potential strategy for ISF-derived arbovirus control.
    MeSH term(s) Aedes ; Animals ; Arboviruses ; Female ; Flavivirus/genetics ; Humans ; Male ; Mosquito Vectors ; Zika Virus/genetics ; Zika Virus Infection
    Language English
    Publishing date 2022-08-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.01062-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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