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Article ; Online: Estimation of energy flow and environmental impacts of quinoa cultivation through life cycle assessment methodology.

Lotfalian Dehkordi, Amin / Forootan, Marziye

Environmental science and pollution research international

2020 Volume 27, Issue 17, Page(s) 21836–21846

Abstract: Quinoa is an adaptable plant that is rich in terms of nutritional properties. Currently, the promotion and cultivation of quinoa are expanding in Iran. The present study aimed to investigate the energy consumption of quinoa grain production and its ... ...

Abstract	Quinoa is an adaptable plant that is rich in terms of nutritional properties. Currently, the promotion and cultivation of quinoa are expanding in Iran. The present study aimed to investigate the energy consumption of quinoa grain production and its environmental impacts through life cycle assessment. In this regard, in order to evaluate the environmental and energy indices, required data were collected from quinoa farmers in Isfahan. The high energy ratio (ER > 1) and positive net energy show that quinoa cultivation is efficient. Based on the results, irrigation water and nitrate fertilizer were identified as the major contributors to energy consumption. Based on the normalization method, the highest and lowest environmental impacts during the production process were related to the indices of marine aquatic ecotoxicity and ozone layer depletion, respectively. Results showed that in the global warming potential impact, 354 kg CO
MeSH term(s)	Agriculture ; Chenopodium quinoa ; Fertilizers ; Global Warming ; Iran
Chemical Substances	Fertilizers
Language	English
Publishing date	2020-04-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-020-08576-9
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Article ; Online: Relationship of Bacteria Isolated from Antral Gastric Biopsy with the Incidence of Dyspepsia in Patients Referred to Mehrad and Labbafinejad Hospitals, Tehran, Iran, in 2018

Mahnaz Mohammadi / Amin Talebi Bezmin Abadi / Farid Rahimi / Mojgan Forootan

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, Vol 30, Iss 1, Pp 85-

2022 Volume 94

Abstract: Introduction: This descriptive cross-sectional study examined the association between the presence of four non-Helicobacter-pylori bacterial species (e.g., Staphylococcus aureus, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Streptococcus ... ...

Abstract	Introduction: This descriptive cross-sectional study examined the association between the presence of four non-Helicobacter-pylori bacterial species (e.g., Staphylococcus aureus, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Streptococcus sanguis) and dyspepsia. Material & Methods: This study included a total of 100 antral biopsy samples isolated from dyspeptic (n=50) or non-dyspeptic (healthy control) (n=50) patients referred to Mehrad and Labafinejad Hospitals, Tehran, Iran, in 2018. Following that, the presence of Staphylococcus aureus, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Streptococcus sanguis was investigated by PCR and using their respective primers, including nuc, PA431CF, iga, and 16s rRNA. Ethics Code (IR.MODARES.REC.1397.241) . Findings: In this study, a total of 50 antral biopsies were isolated from patients with dyspepsia, and 50 antral biopsy specimens were isolated from individuals without dyspepsia during endoscopy. The mean age of the subjects was 48 years (age range: 16-80 years); moreover, the highest age group belonged to the group of 26-46 (24%) years, and the lowest age belonged to the group of 16-26 years (0.06%). The age ranges used in this study had a relatively good population distribution. According to the results of the PCR test, the prevalence rates of Staphylococcus aureus, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Streptococcus sanguis in dyspeptic patients (n=50) were 23 (46%), 3 (6%), 42 (84%), and 0 (0 %), respectively. Moreover, the corresponding prevalence values were 19 (38%), 10 (20%), 45 (90%), and 2 (4%) among the non-dyspeptic control individuals. The presence of these bacteria showed no statistically significant association with the incidence of dyspepsia (P˃0.05). Discussion & Conclusion: Bacterial species living in this area can be highly diverse, and therefore, in addition to other epigenetic involved factors, the studying of other factors, such as environment, nutrition, lifestyle, and the host's genetic, will increase ...
Keywords	colonization ; dyspepsia ; gastric microbiota ; pseudomonas aeruginosa ; staphylococcus aureus ; Medicine ; R ; Medicine (General) ; R5-920
Language	Persian
Publishing date	2022-03-01T00:00:00Z
Publisher	Ilam University of Medical Sciences
Document type	Article ; Online
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Article ; Online: Identification of Streptococcus gallolyticus in tumor samples of Iranian patients diagnosed with colorectal cancer.

Kamali, Negin / Talebi Bezmin Abadi, Amin / Abadi, Bezmin / Rahimi, Farid / Forootan, Mojgan

BMC research notes

2022 Volume 15, Issue 1, Page(s) 316

Abstract: Objective: Clinical outcomes of infection by S. gallolyticus have not been investigated extensively. We aimed to determine the prevalence of S. gallolyticus in tumor specimens obtained from Iranian patients diagnosed with colorectal cancer. Polymerase ... ...

Abstract	Objective: Clinical outcomes of infection by S. gallolyticus have not been investigated extensively. We aimed to determine the prevalence of S. gallolyticus in tumor specimens obtained from Iranian patients diagnosed with colorectal cancer. Polymerase chain reaction was used to confirm the presence of S. gallolyticus in patients' tissue samples. Results: Of 176 patients, 65 were diagnosed with colorectal cancer whereas 111 did not have any colon disease. No correlation was found between age, colonization with S. gallolyticus, gender, or risk factors. Overall, 72 (40%) patients carried S. gallolyticus; only 29% of the patients without colorectal cancer were positive for S. gallolyticus. Diagnosis of colorectal cancer and presence of S. gallolyticus significantly correlated (P = 0.006; odds ratio = 1.46; 95% CI = 1.21-3.87). Among the patients with colorectal cancer, 39 (60%) were positive with S. gallolyticus (P = 0.006) whereas 33 of 111 (29.7%) control subjects were positive for S. gallolyticus (P > 0.05); thus, 70.3% of the control subjects were not infected with S. gallolyticus. We found a high prevalence of S. gallolyticus among an Iranian cohort of patients with colorectal cancer. Despite previous reports, we report a positive correlation between colorectal cancer and S. gallolyticus colonization.
MeSH term(s)	Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/epidemiology ; Humans ; Iran/epidemiology ; Odds Ratio ; Streptococcal Infections/diagnosis ; Streptococcal Infections/epidemiology ; Streptococcus gallolyticus
Language	English
Publishing date	2022-10-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2413336-X
ISSN	1756-0500 ; 1756-0500
ISSN (online)	1756-0500
ISSN	1756-0500
DOI	10.1186/s13104-022-06207-9
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Article ; Online: Comparison of the efficacy of diltiazem versus fluoxetine in the treatment of distal esophageal spasm: A randomized-controlled-trial.

Forootan, Mojgan / Rajabnia, Mohsen / Ghorbanpoor Rassekh, Ahmad / Abdi, Saeed / Fathi, Mobin / Pourhoseingholi, Mohamad Amin / Ketabi Moghadam, Pardis

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

2023

Abstract: Background and study aim: Distal esophageal spasm is an uncommon esophageal motility disorder presenting with non-cardiac chest pain and dysphagia. The main goal of therapy is symptom relief with pharmacologic, endoscopic, and surgical therapies. ... ...

Abstract	Background and study aim: Distal esophageal spasm is an uncommon esophageal motility disorder presenting with non-cardiac chest pain and dysphagia. The main goal of therapy is symptom relief with pharmacologic, endoscopic, and surgical therapies. Pharmacologic treatment is less invasive and is the preferred method of choice. The purpose of this study was to compare the effectiveness of diltiazem versus fluoxetine in the treatment of distal esophageal spasm. Patients and methods: A total of 125 patients with distal esophageal spasm diagnosed using endoscopy, barium esophagogram, and manometry were evaluated. Patients were divided into diltiazem and fluoxetine groups and received a 2-month trial of diltiazem + omeprazole or fluoxetine + omeprazole, respectively. Of 125 patients, 55 were lost to follow up and 70 were eligible for final analysis. Clinical signs and symptoms were assessed before and after therapy using four validated questionnaires: Eckardt score, short form-36, heartburn score, and the hospital anxiety and depression scale. Results: Both regimens significantly relieved symptoms (a decrease in mean Eckardt score of 2.57 and 3.18 for diltiazem and fluoxetine groups, respectively; and a decrease in mean heartburn score by 0.89 and 1.03 for diltiazem and fluoxetine groups, respectively). Patients' quality of life improved based on short form-36 (an increase in mean score of 2.37 and 3.95 for fluoxetine and diltiazem groups, respectively). There was no relationship between patients' improvement and severity of symptoms. Psychological findings based on the hospital anxiety and depression scale were inconsistent (a decrease in mean of 0.143 and 0.57 for fluoxetine and diltiazem groups, respectively; p > 0.05). Conclusion: Fluoxetine and diltiazem were effective for clinical symptom relief in patients with distal esophageal spasm, but were not promising for improving psychological symptoms. Neither regimen was superior in terms of efficacy. Consequently, it is key to consider side effects and comorbidities when choosing a therapy.
Language	English
Publishing date	2023-09-15
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2502114-X
ISSN	2090-2387 ; 1687-1979
ISSN (online)	2090-2387
ISSN	1687-1979
DOI	10.1016/j.ajg.2023.07.002
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Article: Colonization by

Kachuei, Vida / Talebi Bezmin Abadi, Amin / Rahimi, Farid / Forootan, Mojgan

Infection and drug resistance

2020 Volume 13, Page(s) 1411–1417

Abstract: Purpose: Roles and incidence of some microorganisms that transiently or permanently colonize the human stomach are still unknown despite advances in gastroenterology. We aimed to examine the incidence of four microorganisms, : Patients and methods: ... ...

Abstract	Purpose: Roles and incidence of some microorganisms that transiently or permanently colonize the human stomach are still unknown despite advances in gastroenterology. We aimed to examine the incidence of four microorganisms, Patients and methods: Patients (67 females, 33 males; mean age = 49.5 years) were initially examined and diagnosed by a gastroenterologist at the Mehrad Hospital, Tehran, Iran. We enrolled those who underwent the upper gastrointestinal endoscopy because of gastroduodenal conditions. Two antral biopsy samples were taken by endoscopy; the first sample was used for the "rapid urease test" to confirm Results: Based on pathology and endoscopy findings, we divided the patients into three groups: 62 presented with gastritis, 18 with duodenal ulcer, and 20 gastric ulcer. The number of patients with Conclusion: The number of patients without
Language	English
Publishing date	2020-05-13
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2494856-1
ISSN	1178-6973
ISSN	1178-6973
DOI	10.2147/IDR.S254967
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Article ; Online: Helicobacter heilmannii Colonization Is Associated with High Risk for Gastritis.

Mohammadi, Mahnaz / Talebi Bezmin Abadi, Amin / Rahimi, Farid / Forootan, Mojgan

Archives of medical research

2019 Volume 50, Issue 7, Page(s) 423–427

Abstract: Introduction: We aimed to study potential associations between colonization by four common non-pylori Helicobacter species and gastroduodenal diseases by comparing samples from patients infected with H. pylori with samples from non-infected subjects.: ...

Abstract	Introduction: We aimed to study potential associations between colonization by four common non-pylori Helicobacter species and gastroduodenal diseases by comparing samples from patients infected with H. pylori with samples from non-infected subjects. Materials and methods: Patients (n = 190) who were subjected to upper gastrointestinal endoscopy because of gastroduodenal conditions were enrolled in this cross-sectional study. Antral biopsy samples were taken from patients in two major hospitals (Mehrad and Imam-Hossein) in Tehran, Iran, during 2017-2018. DNA was isolated from the biopsy specimens, and PCR amplification was used to identify the Helicobacter species by using their corresponding specific primer sets. Results: Out of 120 cases positive for H. pylori, 46 (38%) were patients with gastritis, 23 (19%) with duodenal ulcer, 11 (9%) with gastric cancer, and 40 (33.3%) with gastric ulcer. Overall, 70 (36%) patients were negative for H. pylori. H. pylori cases were uninfected by any of the other tested Helicobacter species. Among the 70 patients without H. pylori, 34 had gastritis-31 (94%) of these were positive also for H. heilmannii (p = 0.001, Odds Ratio: 51.6; 95% Confidence Intervals: 11.8-225.6). We did not find any patient carrying mixed Helicobacter infections with any non-pylori Helicobacter species in this cohort. Conclusions: Given our evidence about the possibility of involvement of H. heilmannii in patients suffering from gastritis and nonexistence of mixed non-pylori Helicobacter infections, bacteriological testing of subjects negative for H. pylori becomes clinically relevant and important.
MeSH term(s)	Adult ; Aged ; Cross-Sectional Studies ; Female ; Gastritis/pathology ; Helicobacter Infections/etiology ; Helicobacter Infections/pathology ; Helicobacter heilmannii/pathogenicity ; Humans ; Male ; Middle Aged ; Risk Factors ; Young Adult
Language	English
Publishing date	2019-11-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1156844-6
ISSN	1873-5487 ; 0188-4409 ; 0188-0128
ISSN (online)	1873-5487
ISSN	0188-4409 ; 0188-0128
DOI	10.1016/j.arcmed.2019.11.001
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Article: Techno-financial evaluation of a hybrid renewable solution for supplying the predicted power outages by machine learning methods in rural areas

Tamjid Shabestari, Sara / Kasaeian, Alibakhsh / Vaziri Rad, Mohammad Amin / Forootan Fard, Habib / Yan, Wei-Mon / Pourfayaz, Fathollah

Renewable energy. 2022 July, v. 194

2022

Abstract: From a worldwide perspective, increasing grid reliability by applying renewable energies is one of the most affordable and environmentally-friendly options available for governments. In this study, the possible numbers of future rural power outages in ... ...

Abstract	From a worldwide perspective, increasing grid reliability by applying renewable energies is one of the most affordable and environmentally-friendly options available for governments. In this study, the possible numbers of future rural power outages in Iran were predicted using machine learning methods based on nine different prediction models such as PLS Regression, Basian Ridge, and LARS Lasso. Then, the predicted blackouts were imported into the grid tool of HOMER software to analyze a common grid-connected HRES that includes PV, biodiesel generator, and battery bank under three power outage scenarios, including peak-time outages, planned outages, and random outages. The analyzed results until 2040 showed that using renewable sources to electrify possible annual blackouts under a day-hours planned power outage scheme can be an affordable solution with energy costs ranging from 0.066 to 0.070 $/kWh. With less than a 5% increase over the national energy tariff, more than 15% of the supplied electricity was renewable and without any blackouts. Furthermore, the sensitivity analysis showed that the government must keep the power outage's mean repair time to less than 2 h to ensure the effective use of renewables and solve the increasing rural blackouts problem in the hot months of the year.
Keywords	batteries ; biodiesel ; computer software ; electricity ; energy ; prediction ; tariffs ; Iran
Language	English
Dates of publication	2022-07
Size	p. 1303-1325.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2001449-1
ISSN	1879-0682 ; 0960-1481
ISSN (online)	1879-0682
ISSN	0960-1481
DOI	10.1016/j.renene.2022.05.160
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Article ; Online: Carrying a 112 bp-segment in Helicobacter pylori dupA may associate with increased risk of duodenal ulcer.

Fatahi, Golzar / Talebi Bezmin Abadi, Amin / Peerayeh, Shahin Najar / Forootan, Mojgan

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

2019 Volume 73, Page(s) 21–25

Abstract: The discovery of Helicobacter pylori in 1983 challenged researchers around the world to identify this pathogen's major virulence factors. The main rationale for this kind of research was to identify a biomarker associated with specific diseases following ...

Abstract	The discovery of Helicobacter pylori in 1983 challenged researchers around the world to identify this pathogen's major virulence factors. The main rationale for this kind of research was to identify a biomarker associated with specific diseases following H. pylori colonization. Among different investigated virulence factors, duodenal ulcer promoting gene A (dupA) has been found to be associated with duodenal ulcer (DU), but its effect was different in various geographical regions. To determine the prevalence of dupA, we applied both classic primer pairs and our newly developed primers producing a highly conserved segment in PCR method. In our survey, 143 (47%) H. pylori isolates were obtained from 304H. pylori-colonized individuals [age range of 19-92; 113 (37%) males with the mean age of 50 and 191 (63%) females with the mean age of 49]. The presence of the dupA gene was investigated by using the different specific primers. The prevalence of the 112 bp segment isolated from H. pylori strains recovered from DU, GU and atrophy groups were significantly higher (81%, p value = .002, 64%, p = .065, 68% and p = .047 38%, respectively) than our control group, where the prevalence of the 112 bp segment was only 38%. Interestingly, a significant relationship was observed between the occurrence of DU and the presence of the 112 bp segment [p = .002; OR: 6.98; (95% CI: 1.94-25.00)]. Taken as a whole, we believe the 112 bp region of H. pylori dupA may serve as the first detected biomarker for the early detection of DU in patients admitted to hospitals.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Disease Susceptibility ; Duodenal Ulcer/epidemiology ; Duodenal Ulcer/etiology ; Female ; Helicobacter Infections/complications ; Helicobacter Infections/microbiology ; Helicobacter pylori/genetics ; Humans ; Male ; Middle Aged ; Prevalence ; Risk Assessment ; Risk Factors ; Virulence Factors/genetics
Chemical Substances	DupA protein, Helicobacter pylori ; Virulence Factors
Language	English
Publishing date	2019-04-11
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2037068-4
ISSN	1567-7257 ; 1567-1348
ISSN (online)	1567-7257
ISSN	1567-1348
DOI	10.1016/j.meegid.2019.04.009
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Article: Methods to determine limit of detection and limit of quantification in quantitative real-time PCR (qPCR).

Forootan, Amin / Sjöback, Robert / Björkman, Jens / Sjögreen, Björn / Linz, Lucas / Kubista, Mikael

Biomolecular detection and quantification

2017 Volume 12, Page(s) 1–6

Abstract: Quantitative Real-Time Polymerase Chain Reaction, better known as qPCR, is the most sensitive and specific technique we have for the detection of nucleic acids. Even though it has been around for more than 30 years and is preferred in research ... ...

Abstract	Quantitative Real-Time Polymerase Chain Reaction, better known as qPCR, is the most sensitive and specific technique we have for the detection of nucleic acids. Even though it has been around for more than 30 years and is preferred in research applications, it has yet to win broad acceptance in routine practice. This requires a means to unambiguously assess the performance of specific qPCR analyses. Here we present methods to determine the limit of detection (LoD) and the limit of quantification (LoQ) as applicable to qPCR. These are based on standard statistical methods as recommended by regulatory bodies adapted to qPCR and complemented with a novel approach to estimate the precision of LoD.
Language	English
Publishing date	2017-04-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2821770-6
ISSN	2214-7535
ISSN	2214-7535
DOI	10.1016/j.bdq.2017.04.001
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Article: Carrying a 112 bp-segment in Helicobacter pylori dupA may associate with increased risk of duodenal ulcer

Fatahi, Golzar / Forootan, Mojgan / Peerayeh, Shahin Najar / Talebi Bezmin Abadi, Amin

Infection, genetics, and evolution. 2019 Sept., v. 73

2019

Abstract	The discovery of Helicobacter pylori in 1983 challenged researchers around the world to identify this pathogen's major virulence factors. The main rationale for this kind of research was to identify a biomarker associated with specific diseases following H. pylori colonization. Among different investigated virulence factors, duodenal ulcer promoting gene A (dupA) has been found to be associated with duodenal ulcer (DU), but its effect was different in various geographical regions. To determine the prevalence of dupA, we applied both classic primer pairs and our newly developed primers producing a highly conserved segment in PCR method. In our survey, 143 (47%) H. pylori isolates were obtained from 304H. pylori-colonized individuals [age range of 19–92; 113 (37%) males with the mean age of 50 and 191 (63%) females with the mean age of 49]. The presence of the dupA gene was investigated by using the different specific primers. The prevalence of the 112 bp segment isolated from H. pylori strains recovered from DU, GU and atrophy groups were significantly higher (81%, p value = .002, 64%, p = .065, 68% and p = .047 38%, respectively) than our control group, where the prevalence of the 112 bp segment was only 38%. Interestingly, a significant relationship was observed between the occurrence of DU and the presence of the 112 bp segment [p = .002; OR: 6.98; (95% CI: 1.94–25.00)]. Taken as a whole, we believe the 112 bp region of H. pylori dupA may serve as the first detected biomarker for the early detection of DU in patients admitted to hospitals.
Keywords	atrophy ; biomarkers ; duodenal ulcers ; females ; genes ; Helicobacter pylori ; hospitals ; males ; oligodeoxyribonucleotides ; pathogens ; patients ; polymerase chain reaction ; risk ; surveys ; virulence
Language	English
Dates of publication	2019-09
Size	p. 21-25.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2037068-4
ISSN	1567-1348
ISSN	1567-1348
DOI	10.1016/j.meegid.2019.04.009
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