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  1. Article ; Online: l

    Gan, Huaquan / Huang, Yunbao / Wang, Feng / Li, Haiyan / Li, Yulong / Huang, Zexiong

    Optics letters

    2023  Volume 48, Issue 20, Page(s) 5205–5208

    Abstract: ... from one image is a challenging problem. In this Letter, a new l ...

    Abstract The one-dimensional velocity interferometer system for any reflector (VISAR) is widely used in inertial confinement fusion (ICF). Compressed ultrafast photography (CUP) is recently combined with VISAR to enable two-dimensional imaging, in which, the time-varied two-dimensional fringe images reconstruction from one image is a challenging problem. In this Letter, a new l
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.496852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: l

    Ma, Rong / Xie, Qian / Li, Hongyan / Guo, Xiaoqing / Wang, Jian / Li, Yong / Ren, Mihong / Gong, Daoyin / Gao, Tian

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 641894

    Abstract: At present, Stroke is still one of the leading causes of population death worldwide and leads to disability. Traditional Chinese medicine plays an important role in the prevention or treatment of stroke. ...

    Abstract At present, Stroke is still one of the leading causes of population death worldwide and leads to disability. Traditional Chinese medicine plays an important role in the prevention or treatment of stroke.
    Language English
    Publishing date 2021-03-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.641894
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: L

    Dou, Mengying / Zhang, Yao / Shao, Qi / Zhu, Jiali / Li, Wang / Wang, Xueying / Zhang, Cai / Li, Yuanxiao

    Animal biotechnology

    2021  Volume 34, Issue 4, Page(s) 1005–1013

    Abstract: Heat stress (HS) has a negative impact on the health and performance of dairy cows, resulting in economic losses. Damage to the intestinal epithelium is the main cause of the adverse effects of heat stress on bovine health. This study investigated the ... ...

    Abstract Heat stress (HS) has a negative impact on the health and performance of dairy cows, resulting in economic losses. Damage to the intestinal epithelium is the main cause of the adverse effects of heat stress on bovine health. This study investigated the repair capability of
    MeSH term(s) Female ; Cattle ; Animals ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Epithelial Cells/metabolism ; Arginine/pharmacology ; Arginine/metabolism ; Heat-Shock Response ; Inflammation/metabolism ; Cattle Diseases
    Chemical Substances Antioxidants ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2021-12-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2043243-4
    ISSN 1532-2378 ; 1049-5398
    ISSN (online) 1532-2378
    ISSN 1049-5398
    DOI 10.1080/10495398.2021.2009491
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  4. Article ; Online: L

    Zhang, Heng / Guo, Hongbo / Li, Shuangchen / Liu, Yanqiu / He, Xuelei / He, Xiaowei / Hou, Yuqing

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2021  Volume 2021, Page(s) 3640–3645

    Abstract: ... distribution. In this paper, we proposed L ...

    Abstract Fluorescent Molecular Tomography (FMT) is a highly sensitive and noninvasive imaging method that provides three-dimensional distribution of biomarkers by noninvasive detection of fluorescent marker probes. However, due to the light scattering effect and ill-posedness of inverse problems, it is challenging to develop an efficient construction method that can provide the exact location and morphology of the fluorescence distribution. In this paper, we proposed L
    MeSH term(s) Algorithms ; Animals ; Computer Simulation ; Image Processing, Computer-Assisted ; Mice ; Tomography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-12-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC46164.2021.9630236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: L

    Deng, Lei / Li, Guoqi / Pei, Jing / Huang, Jiangshuai

    ISA transactions

    2018  Volume 76, Page(s) 88–96

    Abstract: Locating a pre-given number of key nodes that are connected to external control sources so as to minimize the cost of controlling a directed network ẋ(t)=Ax(t)+Bu(t), known as the minimum cost control problem, is of critical importance. Considering a ... ...

    Abstract Locating a pre-given number of key nodes that are connected to external control sources so as to minimize the cost of controlling a directed network ẋ(t)=Ax(t)+Bu(t), known as the minimum cost control problem, is of critical importance. Considering a network consisting of N nodes with M external control sources, the state of art techniques employ iterative searching to determine the input matrix B that characterizes how nodes are connected to external control sources, in a matrix space R
    Language English
    Publishing date 2018-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2018.03.009
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  6. Article ; Online: (L)

    Li, Zhongshu / Chen, Xiaodan / Andrada, Diego M / Frenking, Gernot / Benkö, Zoltán / Li, Yaqi / Harmer, Jeffrey R / Su, Cheng-Yong / Grützmacher, Hansjörg

    Angewandte Chemie (International ed. in English)

    2017  Volume 56, Issue 21, Page(s) 5744–5749

    Abstract: Carbon phosphides, ... ...

    Abstract Carbon phosphides, C
    Language English
    Publishing date 2017-04-24
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201612247
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  7. Article ; Online: L

    Li, Zhongshu / Hou, Yuanfeng / Li, Yaqi / Hinz, Alexander / Harmer, Jeffrey R / Su, Cheng-Yong / Bertrand, Guy / Grützmacher, Hansjörg

    Angewandte Chemie (International ed. in English)

    2017  Volume 57, Issue 1, Page(s) 198–202

    Abstract: Alkynes usually oligomerize to give rings with a conjugated π-electron system. In contrast, phosphaalkynes, R-C≡P, frequently give compounds with polycyclic structures, which are thermodynamically more stable than the corresponding π-conjugated isomers. ... ...

    Abstract Alkynes usually oligomerize to give rings with a conjugated π-electron system. In contrast, phosphaalkynes, R-C≡P, frequently give compounds with polycyclic structures, which are thermodynamically more stable than the corresponding π-conjugated isomers. The syntheses of the first C
    Language English
    Publishing date 2017-12-05
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201710099
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  8. Article ; Online: An L

    Li, Xiong / Lin, Yangkai / Meng, Xu / Qiu, Yangping / Hu, Bo

    IEEE journal of biomedical and health informatics

    2021  Volume 25, Issue 9, Page(s) 3677–3684

    Abstract: Although the neuroimaging measures build a bridge between genetic variants and disease phenotypes, an assessment of single nucleotide variants changes in brain structure and their clinically influence on the progression of Alzheimer's disease remain ... ...

    Abstract Although the neuroimaging measures build a bridge between genetic variants and disease phenotypes, an assessment of single nucleotide variants changes in brain structure and their clinically influence on the progression of Alzheimer's disease remain largely preliminary. Note that each variant has very weak correlation signal to neuroimaging measures or Alzheimer's disease phenotypes. Therefore, traditional sparse regression-based image genetics approaches confront with unresolvable features, relative high regression error or inapplicability of high-dimensional data. Adopting an [Formula: see text] regularization method, we significantly elevate the regression accuracy of imaging genetics compared with group-sparse multitask regression method. With further analysis on the simulation results, we conclude that multiple regression tasks model may be unsuitable for image genetics. In addition, we carried out a whole genome association analysis between genetic variants (about 388 million loci) and phenotypes (cognition normal, mild cognitive impairment and Alzheimer's disease) with using the [Formula: see text] regularization method. After annotating the effect of all variants by Ensembl Variant Effect Predictor (VEP), our method locates 33 missense variants which can explain 40% phenotype variance. Then, we mapped each missense variant to the nearest gene and carried out pathway enrichment analysis. The Notch signaling pathway and Apoptosis pathway have been reported to be related to the formation of Alzheimer's disease.
    MeSH term(s) Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/genetics ; Brain/diagnostic imaging ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/genetics ; Genome-Wide Association Study ; Humans ; Magnetic Resonance Imaging ; Neuroimaging ; Polymorphism, Single Nucleotide/genetics
    Language English
    Publishing date 2021-09-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2021.3093027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5483: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Enhancing l-Malic Acid Production in

    Yang, Dongdong / Xu, Yingyan / Mo, Li / Shi, Man / Wu, Na / Lu, Ling / Xue, Feng / Xu, Qing / Zhang, Chi

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 9, Page(s) 4869–4879

    Abstract: The efficient production of l-malic acid using ...

    Abstract The efficient production of l-malic acid using
    MeSH term(s) Aspergillus niger/genetics ; Aspergillus niger/metabolism ; Malates/metabolism ; Fermentation ; Escherichia coli/genetics ; Escherichia coli/metabolism ; NAD/metabolism ; Gene Expression ; Aspergillus
    Chemical Substances malic acid (817L1N4CKP) ; Malates ; NAD (0U46U6E8UK)
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c09321
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Glycyl-l-histidyl-l-lysine-Cu

    Deng, Mingming / Zhang, Qin / Yan, Liming / Bian, Yiding / Li, Ruixia / Gao, Jinghan / Wang, Yingxi / Miao, Jinrui / Li, Jiaye / Zhou, Xiaoming / Hou, Gang

    Journal of cachexia, sarcopenia and muscle

    2023  Volume 14, Issue 3, Page(s) 1365–1380

    Abstract: ... sectional area elevated (1055 ± 552.4 μm: Conclusions: Plasma glycyl-l-histidyl-l-lysine level ... associated with skeletal muscle mass. Exogenous administration of glycyl-l-histidyl-l-lysine-Cu ...

    Abstract Background: Skeletal muscle dysfunction is an important co-morbidity in patients with chronic obstructive pulmonary disease (COPD) and is significantly associated with increased mortality. Oxidative stress has been demonstrated an important trigger for COPD-related skeletal muscle dysfunction. Glycine-histidine-lysine (GHK) is an active tripeptide, which is a normal component of human plasma, saliva, and urine; promotes tissue regeneration; and acts as an anti-inflammatory and antioxidant properties. The purpose of this study was to determine whether GHK is involved in COPD-related skeletal muscle dysfunction.
    Methods: The plasma GHK level in patients with COPD (n = 9) and age-paired healthy subjects (n = 11) were detected using reversed-phase high-performance liquid chromatography. The complex GHK with Cu (GHK-Cu) was used in in vitro (C2C12 myotubes) and in vivo experiments (cigarette smoking [CS]-exposure mouse model) to explore the involvement of GHK in CS-induced skeletal muscle dysfunction.
    Results: Compared with healthy control, plasma GHK levels were decreased in patients with COPD (70.27 ± 38.87 ng/mL vs. 133.0 ± 54.54 ng/mL, P = 0.009). And plasma GHK levels in patients with COPD were associated with pectoralis muscle area (R = 0.684, P = 0.042), inflammatory factor TNF-α (R = -0.696, P = 0.037), and antioxidative stress factor SOD2 (R = 0.721, P = 0.029). GHK-Cu was found to rescue CSE-induced skeletal muscle dysfunction in C2C12 myotubes, as evidenced by increased expression of myosin heavy chain, reduced expression of MuRF1 and atrogin-1, elevated mitochondrial content, and enhanced resistance to oxidative stress. In CS-induced muscle dysfunction C57BL/6 mice, GHK-Cu treatment (0.2 and 2 mg/kg) reduces CS-induced muscle mass loss (skeletal muscle weight (1.19 ± 0.09% vs. 1.29 ± 0.06%, 1.40 ± 0.05%; P < 0.05) and muscle cross-sectional area elevated (1055 ± 552.4 μm
    Conclusions: Plasma glycyl-l-histidyl-l-lysine level in patients with chronic obstructive pulmonary disease was significantly decreased and was significantly associated with skeletal muscle mass. Exogenous administration of glycyl-l-histidyl-l-lysine-Cu
    MeSH term(s) Humans ; Mice ; Animals ; Lysine/metabolism ; Sirtuin 1/metabolism ; Cigarette Smoking ; Mice, Inbred C57BL ; Muscle, Skeletal/metabolism ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Antioxidants/metabolism ; Pulmonary Disease, Chronic Obstructive/metabolism
    Chemical Substances Lysine (K3Z4F929H6) ; Sirtuin 1 (EC 3.5.1.-) ; Antioxidants
    Language English
    Publishing date 2023-03-10
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2586864-0
    ISSN 2190-6009 ; 2190-5991
    ISSN (online) 2190-6009
    ISSN 2190-5991
    DOI 10.1002/jcsm.13213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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