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  1. Article ; Online: Ultra-short-term forecasting model of power load based on fusion of power spectral density and Morlet wavelet.

    Liang, Lihe / Cui, Jinying / Zhao, Juanjuan / Qiang, Yan / Zhao, Juanjuan

    Mathematical biosciences and engineering : MBE

    2024  Volume 21, Issue 2, Page(s) 3391–3421

    Abstract: An accurate ultra-short-term time series prediction of a power load is an important guarantee for power dispatching and the safe operation of power systems. Problems of the current ultra-short-term time series prediction algorithms include low prediction ...

    Abstract An accurate ultra-short-term time series prediction of a power load is an important guarantee for power dispatching and the safe operation of power systems. Problems of the current ultra-short-term time series prediction algorithms include low prediction accuracy, difficulty capturing the local mutation features, poor stability, and others. From the perspective of series decomposition, a multi-scale sequence decomposition model (TFDNet) based on power spectral density and the Morlet wavelet transform is proposed that combines the multidimensional correlation feature fusion strategy in the time and frequency domains. By introducing the time-frequency energy selection module, the "prior knowledge" guidance module, and the sequence denoising decomposition module, the model not only effectively delineates the global trend and local seasonal features, completes the in-depth information mining of the smooth trend and fluctuating seasonal features, but more importantly, realizes the accurate capture of the local mutation seasonal features. Finally, on the premise of improving the forecasting accuracy, single-point load forecasting and quantile probabilistic load forecasting for ultra-short-term load forecasting are realized. Through the experiments conducted on three public datasets and one private dataset, the TFDNet model reduces the mean square error (MSE) and mean absolute error (MAE) by 19.80 and 11.20% on average, respectively, as compared with the benchmark method. These results indicate the potential applications of the TFDNet model.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2024150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Engineered g-C

    Liu, Juanjuan / Wang, Shuaijun / Zhao, Chaocheng / Zheng, Jingtang

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 3

    Abstract: Photocatalysis plays a vital role in sustainable energy conversion and environmental remediation because of its economic, eco-friendly, and effective characteristics. Nitrogen-rich graphitic carbon nitride (g- ... ...

    Abstract Photocatalysis plays a vital role in sustainable energy conversion and environmental remediation because of its economic, eco-friendly, and effective characteristics. Nitrogen-rich graphitic carbon nitride (g-C
    Language English
    Publishing date 2023-01-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13030499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Two Novel

    Qiao, Guanghang / Zhao, Juan / Liu, Juanjuan / Tan, Xiaoqian / Qin, Wentao

    Biology

    2022  Volume 11, Issue 10

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11101459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Molecular mechanism of miRNA mediated biosynthesis of secondary metabolites in medicinal plants.

    Li, Hongwei / Guo, Ziyi / Xu, Mengwei / Zhao, Juanjuan / Xu, Delin

    Plant physiology and biochemistry : PPB

    2024  Volume 208, Page(s) 108524

    Abstract: Plant secondary metabolites are important raw materials for the pharmaceutical industry, and their biosynthetic processes are subject to diverse and precise regulation by miRNA. The identification of miRNA molecules in medicinal plants and exploration of ...

    Abstract Plant secondary metabolites are important raw materials for the pharmaceutical industry, and their biosynthetic processes are subject to diverse and precise regulation by miRNA. The identification of miRNA molecules in medicinal plants and exploration of their mechanisms not only contribute to a deeper understanding of the molecular genetic mechanisms of plant growth, development and resistance to stress, but also provide a theoretical basis for elucidating the pharmacological effects of authentic medicinal materials and constructing bioreactors for the synthesis of medicinal secondary metabolite components. This paper summarizes the research reports on the discovery of miRNA in medicinal plants and their regulatory mechanisms on the synthesis of secondary metabolites by searching the relevant literature in public databases. It summarizes the currently discovered miRNA and their functions in medicinal plants, and summarizes the molecular mechanisms regulating the synthesis and degradation of secondary metabolites. Furthermore, it provides a prospect for the research and development of medicinal plant miRNA. The compiled information contributes to a comprehensive understanding of the research progress on miRNA in medicinal plants and provides a reference for the industrial development of related secondary metabolite biosynthesis.
    MeSH term(s) Plants, Medicinal/genetics ; Plants, Medicinal/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Secondary Metabolism/genetics
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2024-03-15
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 742978-2
    ISSN 1873-2690 ; 0981-9428
    ISSN (online) 1873-2690
    ISSN 0981-9428
    DOI 10.1016/j.plaphy.2024.108524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Long-circulating nanoparticles as passive targeting nanocarriers for the treatment of thrombosis.

    Li, Junyao / Lu, Keqiang / Sun, Shaokai / Peng, Juanjuan / Zhao, Lingzhi

    Nanoscale

    2024  Volume 16, Issue 12, Page(s) 6132–6141

    Abstract: Thrombosis is the major cause of cardiovascular diseases. Only a small subset of patients could benefit from thrombolytic therapy due to the high bleeding risk brought about by the repeated administration of thrombolytic drugs. Nanoparticles with ... ...

    Abstract Thrombosis is the major cause of cardiovascular diseases. Only a small subset of patients could benefit from thrombolytic therapy due to the high bleeding risk brought about by the repeated administration of thrombolytic drugs. Nanoparticles with targeting ligands have been developed as nanocarriers of thrombolytic drugs to deliver the drug to the thrombus through active targeting. However, the passive targeting effect of nanoparticles on the thrombus is yet to be investigated. Herein, we prepared silica cross-linked micelles (SCLMs) with a long blood circulation half-life as drug carriers to target the thrombus through passive targeting. Compared with SCLMs modified with an active targeting ligand cRGD, the SCLMs exhibited similar targeting behavior to the thrombus
    MeSH term(s) Mice ; Animals ; Humans ; Fibrinolytic Agents/pharmacology ; Fibrinolytic Agents/therapeutic use ; Drug Carriers/therapeutic use ; Thrombosis/drug therapy ; Drug Delivery Systems ; Nanoparticles ; Micelles
    Chemical Substances Fibrinolytic Agents ; Drug Carriers ; Micelles
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d4nr00252k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: TNFSF15 inhibits progression of diabetic retinopathy by blocking pyroptosis via interacting with GSDME.

    Zhao, Hongkun / Dai, Yating / Li, Yunqin / Li, Juanjuan / Li, Hua

    Cell death & disease

    2024  Volume 15, Issue 2, Page(s) 118

    Abstract: Diabetic retinopathy is a common microvascular complication of diabetes and a leading cause of blindness. Pyroptosis has emerged as a mechanism of cell death involved in diabetic retinopathy pathology. This study explored the role of GSDME-mediated ... ...

    Abstract Diabetic retinopathy is a common microvascular complication of diabetes and a leading cause of blindness. Pyroptosis has emerged as a mechanism of cell death involved in diabetic retinopathy pathology. This study explored the role of GSDME-mediated pyroptosis and its regulation by TNFSF15 in diabetic retinopathy. We found GSDME was upregulated in the progression of diabetic retinopathy. High glucose promoted GSDME-induced pyroptosis in retinal endothelial cells and retinal pigment epithelial cells, attributed to the activation of caspase-3 which cleaves GSDME to generate the pyroptosis-executing N-terminal fragment. TNFSF15 was identified as a binding partner and inhibitor of GSDME-mediated pyroptosis. TNFSF15 expression was increased by high glucose but suppressed by the caspase-3 activator Raptinal. Moreover, TNFSF15 protein inhibited high glucose- and Raptinal-induced pyroptosis by interacting with GSDME in retinal cells. Collectively, our results demonstrate TNFSF15 inhibits diabetic retinopathy progression by blocking GSDME-dependent pyroptosis of retinal cells, suggesting the TNFSF15-GSDME interaction as a promising therapeutic target for diabetic retinopathy.
    MeSH term(s) Humans ; Pyroptosis/physiology ; Diabetic Retinopathy/genetics ; Diabetic Retinopathy/metabolism ; Caspase 3/metabolism ; Endothelial Cells/metabolism ; Glucose/metabolism ; Diabetes Mellitus/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 15/genetics ; Tumor Necrosis Factor Ligand Superfamily Member 15/metabolism ; Cyclopentanes ; Fluorenes
    Chemical Substances raptinal ; Caspase 3 (EC 3.4.22.-) ; Glucose (IY9XDZ35W2) ; TNFSF15 protein, human ; Tumor Necrosis Factor Ligand Superfamily Member 15 ; Cyclopentanes ; Fluorenes
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-024-06499-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ratio of hemoglobin to red cell distribution width: an inflammatory predictor of survival in AIDS-related DLBCL.

    Chen, Juanjuan / Wu, Yihua / Zhao, Han / Ruan, Guangjing / Qin, Shanfang

    Frontiers in immunology

    2024  Volume 15, Page(s) 1354325

    Abstract: Background: Despite the introduction of combined antiretroviral therapy, AIDS-related diffuse large B-cell lymphoma (AR-DLBCL) remains a prominent cancer among individuals living with HIV with a suboptimal prognosis. Identifying independent prognostic ... ...

    Abstract Background: Despite the introduction of combined antiretroviral therapy, AIDS-related diffuse large B-cell lymphoma (AR-DLBCL) remains a prominent cancer among individuals living with HIV with a suboptimal prognosis. Identifying independent prognostic markers could improve risk stratification.
    Methods: In this multicenter retrospective cohort study spanning years 2011 to 2019, 153 eligible patients with AR-DLBCL were examined. Overall survival (OS) factors were analyzed using Kaplan-Meier curves, and univariate and multivariate Cox proportional hazards models. The discriminatory ability of the risk score was evaluated by examining the area under the receiver operating characteristic curve.
    Results: The study included 153 patients with a median age of 47 years (interquartile range [IQR] 39-58), 83.7% of whom were men. The median follow-up was 12.0 months (95% confidence interval [CI], 8.5-15.5), with an OS rate of 35.9%. Among the potential inflammatory markers examined, only the ratio of hemoglobin (g/dL) to red cell distribution width (%) (Hb/RDW) emerged as an independent prognostic parameter for OS in the training (hazard ratios [HR] = 2.645, 95% CI = 1.267-5.522,
    Conclusion: We identified a cost-effective and readily available inflammatory biomarker, the Hb/RDW ratio, as an independent predictor of outcomes in patients with AR-DLBCL. Its integration into the IPI score partially improves prognostic accuracy.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Acquired Immunodeficiency Syndrome ; Erythrocyte Indices ; Hemoglobins ; Lymphoma, Large B-Cell, Diffuse/pathology ; Prognosis ; Retrospective Studies ; Adult
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1354325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: CD20 × CD3 bispecific antibodies for lymphoma therapy: latest updates from ASCO 2023 annual meeting.

    Liu, Xinyuan / Zhao, Juanjuan / Guo, Xiangqian / Song, Yongping

    Journal of hematology & oncology

    2023  Volume 16, Issue 1, Page(s) 90

    Abstract: Multiple bispecific antibodies (bsAbs) have been approved for cancer immunotherapy. Several CD20 × CD3 bsAbs have demonstrated significant anti-B-cell non-Hodgkin lymphoma (NHL) activity by engaging T cells to target ... ...

    Abstract Multiple bispecific antibodies (bsAbs) have been approved for cancer immunotherapy. Several CD20 × CD3 bsAbs have demonstrated significant anti-B-cell non-Hodgkin lymphoma (NHL) activity by engaging T cells to target CD20
    MeSH term(s) Humans ; Antibodies, Bispecific/therapeutic use ; Antibodies, Monoclonal/therapeutic use ; Antigens, CD20 ; Lymphoma/drug therapy ; Lymphoma, B-Cell ; Antineoplastic Agents/therapeutic use
    Chemical Substances glofitamab (06P3KLK2J8) ; Antibodies, Bispecific ; Antibodies, Monoclonal ; Antigens, CD20 ; Antineoplastic Agents
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429631-4
    ISSN 1756-8722 ; 1756-8722
    ISSN (online) 1756-8722
    ISSN 1756-8722
    DOI 10.1186/s13045-023-01488-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Attaining inhibition of sneak current and versatile logic operations in a singular halide perovskite memristive device by introducing appropriate interface barriers.

    He, Song / Yu, Xingyu / Wang, Juanjuan / Zhong, WenKang / Cheng, Baochang / Zhao, Jie

    Nanoscale

    2024  Volume 16, Issue 3, Page(s) 1102–1114

    Abstract: Emerging resistive switching devices hold the potential to realize densely packed passive nanocrossbar arrays, suitable for deployment as random access memory devices (ReRAMs) in both embedded and high-capacity storage applications. In this study, we ... ...

    Abstract Emerging resistive switching devices hold the potential to realize densely packed passive nanocrossbar arrays, suitable for deployment as random access memory devices (ReRAMs) in both embedded and high-capacity storage applications. In this study, we have engineered ReRAMs comprising ITO/(UVO-treated) amorphous ZnO (a-ZnO)/MAPbI
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr04633h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Isolation and characterization of mpox virus from the first mpox case in Shenzhen, China.

    Cheng, Lin / Yang, Liuqing / Wang, Miao / Peng, Yabo / Wang, Haiyan / Yang, Xiaoxiang / Zhao, Juanjuan / Zhang, Mingxia / Wang, Fuxiang / Zhang, Zheng

    Virologica Sinica

    2024  

    Language English
    Publishing date 2024-01-20
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1011219-4
    ISSN 1995-820X ; 1000-3223 ; 1003-5125
    ISSN (online) 1995-820X
    ISSN 1000-3223 ; 1003-5125
    DOI 10.1016/j.virs.2024.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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