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  1. Book: Xian dai ming Zhong yi nan ke jue ji

    Chen, Wushan

    2002  

    Title translation Best practices of famous Modern Chinese traditional doctors in male diseases.
    Title variant Nan ke jue ji
    Author's details Chen Wushan bian zhu
    MeSH term(s) Genital Diseases, Male/drug therapy ; Medicine, Chinese Traditional
    Language Chinese
    Size 2, 10, 467 p. ;, 20 cm.
    Edition Di 1 ban.
    Publisher Ke xue ji shu wen xian chu ban she
    Publishing place Beijing Shi
    Document type Book
    ISBN 9787502338725 ; 7502338721
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Book: Xian dai ming Zhong yi bu yun bu yu zhen zhi jue ji

    Chen, Wushan

    (Xian dai Zhong yi lin chuang cong shu)

    2002  

    Title translation Modern famous Chinese traditional doctors' best practice in diagnosis and treatment of infertility.
    Title variant Zhong yi bu yun bu yu zhen zhi jue ji
    Author's details zhu bian Chen Wushan, Liu Ying ; bian wei Qiu Jianhua, Qi Guoyuan
    Series title Xian dai Zhong yi lin chuang cong shu
    MeSH term(s) Infertility, Female/drug therapy ; Infertility, Male/drug therapy ; Medicine, Chinese Traditional.
    Language Chinese
    Size 6, 355 p. ;, 21 cm.
    Edition Di 1 ban.
    Publisher Ke xue ji shu wen xian chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787502341503 ; 7502341501
    Database Catalogue of the US National Library of Medicine (NLM)

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  3. Article ; Online: Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice.

    Li, Jinyu / Wei, Yi / Li, Xue / Zhu, Dashuai / Nie, Bo / Zhou, Jingwei / Lou, Lixia / Dong, Bin / Wu, Aiming / Che, Yongzhe / Chen, Meng / Zhu, Lingqun / Mu, Mingwei / Chai, Limin

    BMC complementary and alternative medicine

    2017  Volume 17, Issue 1, Page(s) 12

    Abstract: Background: Xian-Fang-Huo-Ming-Yin (XFHM), a traditional herbal formula, has been used to treat ...

    Abstract Background: Xian-Fang-Huo-Ming-Yin (XFHM), a traditional herbal formula, has been used to treat sores and carbuncles for hundreds of years in Asia. Nowadays, its clinical effects in treatment of rheumatoid arthritis (RA) have been validated. In this study, we want to study its possible molecular mechanisms of regulating the differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis (CIA) mice for RA treatment.
    Methods: A high performance liquid chromatography-electrospray ionization/mass spectrometer (HPLC-ESI/MS
    Results: In our study. 21 different dominant chemical constituents were identified in XFHM. Treatment with XFHM suppressed the pathological changes in arthrosis of CIA. Additionally, XFHM down-regulated the proliferation and differentiation of CD3
    Conclusions: XFHM can regulate and maintain the immunologic balance of lymphocytic immunity and inhibit the production of pro-inflammatory cytokines, thus suppressing the pathological changes of RA. Therefore, XFHM may be used as an application of traditional medicine against RA in modern complementary and alternative therapeutics.
    MeSH term(s) Animals ; Arthritis/drug therapy ; Arthritis/genetics ; Arthritis/immunology ; Arthritis/physiopathology ; Cell Differentiation ; Collagen/adverse effects ; Cytokines/genetics ; Cytokines/immunology ; Disease Models, Animal ; Drugs, Chinese Herbal/administration & dosage ; Humans ; Janus Kinases/genetics ; Janus Kinases/immunology ; Lymphocytes/cytology ; Lymphocytes/immunology ; Male ; Mice ; Mice, Inbred DBA ; NF-kappa B/genetics ; NF-kappa B/immunology
    Chemical Substances Cytokines ; Drugs, Chinese Herbal ; NF-kappa B ; Collagen (9007-34-5) ; Janus Kinases (EC 2.7.10.2)
    Language English
    Publishing date 2017-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050429-9
    ISSN 1472-6882 ; 1472-6882
    ISSN (online) 1472-6882
    ISSN 1472-6882
    DOI 10.1186/s12906-016-1526-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice

    Li, Jinyu / Wei, Yi / Li, Xue / Zhu, Dashuai / Nie, Bo / Zhou, Jingwei / Lou, Lixia / Dong, Bin / Wu, Aiming / Che, Yongzhe / Chen, Meng / Zhu, Lingqun / Mu, Mingwei / Chai, Limin

    BMC Complement Altern Med. 2017 Dec., v. 17, no. 1 p.12-12

    2017  

    Abstract: BACKGROUND: Xian-Fang-Huo-Ming-Yin (XFHM), a traditional herbal formula, has been used to treat ...

    Abstract BACKGROUND: Xian-Fang-Huo-Ming-Yin (XFHM), a traditional herbal formula, has been used to treat sores and carbuncles for hundreds of years in Asia. Nowadays, its clinical effects in treatment of rheumatoid arthritis (RA) have been validated. In this study, we want to study its possible molecular mechanisms of regulating the differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis (CIA) mice for RA treatment. METHODS: A high performance liquid chromatography-electrospray ionization/mass spectrometer (HPLC-ESI/MSⁿ) system was used to analyze the constituents of XFHM granules. An arthritics mouse model was induced by collagen and leflunomide (LEF) was used as a positive control medicine. Pathological changes at the metatarsophalangeal joint were studied through Safranin O and immunohistochemical staining. The differentiation of T, B and NK cells was examined by flow cytometry and pro-inflammatory cytokines were assayed using an Inflammation Antibody Array assay. The expression of key molecules of the nuclear factor κB (NF-κB) and Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathways in spleen were studied by western-blot analysis. RESULTS: In our study. 21 different dominant chemical constituents were identified in XFHM. Treatment with XFHM suppressed the pathological changes in arthrosis of CIA. Additionally, XFHM down-regulated the proliferation and differentiation of CD3⁺ T cells and CD3⁻CD19⁺ B cells significantly. However, XFHM had no significant effect on CD3⁻NK1.1⁺ NK cells. Further study showed that the production of pro-inflammatory cytokines had been suppressed by inhibiting the activation of NF-κB and JAK/STAT signaling. CONCLUSIONS: XFHM can regulate and maintain the immunologic balance of lymphocytic immunity and inhibit the production of pro-inflammatory cytokines, thus suppressing the pathological changes of RA. Therefore, XFHM may be used as an application of traditional medicine against RA in modern complementary and alternative therapeutics.
    Keywords antibodies ; collagen ; complement ; cytokines ; electrospray ionization mass spectrometry ; flow cytometry ; immunity ; immunohistochemistry ; inflammation ; mice ; models ; non-specific protein-tyrosine kinase ; rheumatoid arthritis ; spectrometers ; spleen ; therapeutics ; traditional medicine ; Asia
    Language English
    Dates of publication 2017-12
    Size p. 12.
    Publishing place BioMed Central
    Document type Article ; Online
    Note Resource is Open Access
    ZDB-ID 2050429-9
    ISSN 1472-6882
    ISSN 1472-6882
    DOI 10.1186/s12906-016-1526-x
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: The Complexity of Interferon Signaling in Host Defense against Protozoan Parasite Infection.

    Deng, Silu / Graham, Marion L / Chen, Xian-Ming

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 2

    Abstract: Protozoan parasites, such ... ...

    Abstract Protozoan parasites, such as
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12020319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Zhong guo jin xian dai ren wu ming hao da ci dian

    Chen, Yutang

    1993  

    Title variant Zhong-guo jin-xian-dai ren-wu ming-hao da ci-dian
    Author's details Chen yu tang bian zhu
    Language Chinese
    Size Getr. Zählung
    Edition Di 1 ban
    Publisher Zhe jiang gu ji chu ban she
    Publishing place Hang zhou
    Document type Book
    ISBN 7805180253 ; 9787805180250
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article ; Online: An Optimized Schwarz Method for the Optical Response Model Discretized by HDG Method.

    Chen, Jia-Fen / Gu, Xian-Ming / Li, Liang / Zhou, Ping

    Entropy (Basel, Switzerland)

    2023  Volume 25, Issue 4

    Abstract: An optimized Schwarz domain decomposition method (DDM) for solving the local optical response model (LORM) is proposed in this paper. We introduce a hybridizable discontinuous Galerkin (HDG) scheme for the discretization of such a model problem based on ... ...

    Abstract An optimized Schwarz domain decomposition method (DDM) for solving the local optical response model (LORM) is proposed in this paper. We introduce a hybridizable discontinuous Galerkin (HDG) scheme for the discretization of such a model problem based on a triangular mesh of the computational domain. The discretized linear system of the HDG method on each subdomain is solved by a sparse direct solver. The solution of the interface linear system in the domain decomposition framework is accelerated by a Krylov subspace method. We study the spectral radius of the iteration matrix of the Schwarz method for the LORM problems, and thus propose an optimized parameter for the transmission condition, which is different from that for the classical electromagnetic problems. The numerical results show that the proposed method is effective.
    Language English
    Publishing date 2023-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25040693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Publisher Correction: A sequence-based evolutionary distance method for Phylogenetic analysis of highly divergent proteins.

    Cao, Wei / Wu, Lu-Yun / Xia, Xia-Yu / Chen, Xiang / Wang, Zhi-Xin / Pan, Xian-Ming

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 23000

    Language English
    Publishing date 2023-12-28
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50520-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Phase Deflectometry for Defect Detection of High Reflection Objects.

    Cheng, Xian-Ming / Wang, Ting-Ting / Zhu, Wen-Bin / Shi, Bai-Di / Chen, Wei

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: A method for detecting the surface defects of high reflection objects using phase deflection is proposed. The abrupt change in the surface gradient at the defect leads to the change in the fringe phase. Therefore, Gray code combined with a four-step ... ...

    Abstract A method for detecting the surface defects of high reflection objects using phase deflection is proposed. The abrupt change in the surface gradient at the defect leads to the change in the fringe phase. Therefore, Gray code combined with a four-step phase-shift method was employed to obtain the surface gradients to characterize the defects. Then, through the double surface illumination model, the relationship between illumination intensity and phase was established. The causes of periodic error interference were analyzed, and the method of adjusting the fringe width to eliminate it was proposed. Finally, experimental results showed the effectiveness of the proposed method.
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A sequence-based evolutionary distance method for Phylogenetic analysis of highly divergent proteins.

    Cao, Wei / Wu, Lu-Yun / Xia, Xia-Yu / Chen, Xiang / Wang, Zhi-Xin / Pan, Xian-Ming

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 20304

    Abstract: Because of the limited effectiveness of prevailing phylogenetic methods when applied to highly divergent protein sequences, the phylogenetic analysis problem remains challenging. Here, we propose a sequence-based evolutionary distance algorithm termed ... ...

    Abstract Because of the limited effectiveness of prevailing phylogenetic methods when applied to highly divergent protein sequences, the phylogenetic analysis problem remains challenging. Here, we propose a sequence-based evolutionary distance algorithm termed sequence distance (SD), which innovatively incorporates site-to-site correlation within protein sequences into the distance estimation. In protein superfamilies, SD can effectively distinguish evolutionary relationships both within and between protein families, producing phylogenetic trees that closely align with those based on structural information, even with sequence identity less than 20%. SD is highly correlated with the similarity of the protein structure, and can calculate evolutionary distances for thousands of protein pairs within seconds using a single CPU, which is significantly faster than most protein structure prediction methods that demand high computational resources and long run times. The development of SD will significantly advance phylogenetics, providing researchers with a more accurate and reliable tool for exploring evolutionary relationships.
    MeSH term(s) Phylogeny ; Evolution, Molecular ; Sequence Alignment ; Biological Evolution ; Proteins/genetics ; Proteins/chemistry ; Algorithms
    Chemical Substances Proteins
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-47496-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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