LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 195922

Search options

  1. Article ; Online: Lin

    Xu, Haoyu / Tan, Shaojing / Zhao, Yu / Zhang, Lin / Cao, Weiyun / Li, Xing / Tian, Jiayi / Wang, Xiaojing / Li, Xiaoyan / Wang, Fengchao / Cao, Jiani / Zhao, Tongbiao

    Cell proliferation

    2023  Volume 56, Issue 11, Page(s) e13490

    Abstract: ... myeloid repopulating activity are specifically enriched in a Lin ...

    Abstract Despite extensive characterization of the state and function of haematopoietic stem cells (HSCs), the use of transcription factors to define the HSC population is still limited. We show here that the HSC population in mouse bone marrow can be defined by the distinct expression levels of Spi1 and Gata1. By using a double fluorescence knock-in mouse model, PGdKI, in which the expression levels of PU.1 and GATA-1 are indicated by the expression of GFP and mCherry, respectively, we uncover that the HSCs with lymphoid and myeloid repopulating activity are specifically enriched in a Lin
    MeSH term(s) Mice ; Animals ; Cell Lineage ; Hematopoietic Stem Cells/metabolism ; Receptor Protein-Tyrosine Kinases ; Proto-Oncogene Proteins c-kit/metabolism ; Bone Marrow Cells/metabolism ; Mice, Inbred C57BL
    Chemical Substances Receptor Protein-Tyrosine Kinases (EC 2.7.10.1) ; Proto-Oncogene Proteins c-kit (EC 2.7.10.1)
    Language English
    Publishing date 2023-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1064202-x
    ISSN 1365-2184 ; 0008-8730 ; 0960-7722
    ISSN (online) 1365-2184
    ISSN 0008-8730 ; 0960-7722
    DOI 10.1111/cpr.13490
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 532: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Correction: Zhang, N.; Lin, C. The Image Definition Assessment of Optoelectronic Tracking Equipment Based on the BRISQUE Algorithm with Gaussian Weights.

    Zhang, Ning / Lin, Cui

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 14

    Abstract: There was an error in the original publication [ ... ]. ...

    Abstract There was an error in the original publication [...].
    Language English
    Publishing date 2023-07-12
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23146323
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Correction for Lin et al., "Clinical Diagnostic Performance of Droplet Digital PCR for Suspected Bloodstream Infections".

    Lin, Ke / Zhao, Yuanhan / Xu, Bin / Yu, Shenglei / Fu, Zhangfan / Zhang, Yi / Wang, Hongyu / Song, Jieyu / Fan, Mingxiang / Zhou, Yang / Ai, Jingwen / Qiu, Chao / Zhang, Haocheng / Zhang, Wenhong

    Microbiology spectrum

    2023  Volume 12, Issue 1, Page(s) e0153423

    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01534-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Lin et al. Respond.

    Lin, Wen-Chieh / Clark, Robin E / Zhang, Jianying / O'Connell, Elizabeth / Bharel, Monica

    American journal of public health

    2016  Volume 106, Issue 3, Page(s) 571–572

    MeSH term(s) Emergency Service, Hospital/statistics & numerical data ; Female ; Homeless Persons/statistics & numerical data ; Hospitalization/statistics & numerical data ; Humans ; Male ; Medicaid/statistics & numerical data
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2015.303055
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.279: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: [Optimization of isolation and culture of Lin

    Li, Duan-Duan / Shi, Shan-Hui / Zhou, Mi / Ma, Xiu-Xia / Gao, Jian-Zhong / Zhang, Ya-Qiong / Yang, Li-Wen / Zuo, Lin

    Sheng li xue bao : [Acta physiologica Sinica

    2017  Volume 69, Issue 4, Page(s) 477–484

    Abstract: ... on the isolation of Lin ...

    Abstract Cardiac stem cells (CSCs) transplantation has been recognized to be effective on the treatment of myocardial infarction (MI), but some techniques still need to be developed in the isolation and culture of CSCs, which is the key problem restricting the clinical application of CSCs. This study was focused on the isolation of Lin
    MeSH term(s) Animals ; Animals, Newborn ; Flow Cytometry ; Mice ; Mice, Inbred C57BL ; Myocardium/cytology ; Primary Cell Culture ; Stem Cells/cytology
    Language Chinese
    Publishing date 2017-08-17
    Publishing country China
    Document type Journal Article
    ZDB-ID 604308-2
    ISSN 0371-0874
    ISSN 0371-0874
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 386: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: The Joe-Lin Operative Classification System for Pediatric Lumbosacral Spondylolysis and Spondylolisthesis.

    Lin, Tao / Zhang, Zheng / Jiang, Qingjun / Yin, Jia / Ma, Xiao / Wang, Ce / Zhou, Xuhui

    World neurosurgery

    2020  Volume 142, Page(s) e18–e31

    Abstract: Objective: To propose and validate a novel and comprehensive classification of lumbosacral spondylolysis and spondylolisthesis in the pediatric population according to surgical managements.: Methods: Cases of pediatric lumbosacral (L5/S1 level) ... ...

    Abstract Objective: To propose and validate a novel and comprehensive classification of lumbosacral spondylolysis and spondylolisthesis in the pediatric population according to surgical managements.
    Methods: Cases of pediatric lumbosacral (L5/S1 level) spondylolysis and spondylolisthesis were reviewed. Lumbar Japanese Orthopedics Association score, health-related quality of life, spondylolisthesis, lumbosacral disc degeneration, and dysplastic features were included for evaluation of outcomes after surgery. We also conducted a reliability study to assess the classification.
    Results: A classification containing 4 types and a tentative treatment algorithm were proposed: type 1, direct pars repair without segmented fusion, for which the pedicle screw-U rod system is suitable; type 2, simple L5-S1 fusion; type 3, simple L4-S1 fusion; and type 4, simple L5-S2 fusion. All types of spondylolisthesis were suggested to achieve complete reduction and decompression. A total of 162 patients were included and we also reviewed the outcomes of patients in each type. All patients achieved satisfied outcomes. The reliability study showed that the average interobserver agreement was 89.5% (range, 85.2%-92.6%), with κ value of 0.862 (range, 0.802-0.901). Intraobserver agreement ranged from 88.9% to 92.6%, with an average κ value of 0.868 (range, 0.835-0.901).
    Conclusions: In our study, we proposed and validated a novel comprehensive classification of pediatric lumbosacral spondylolysis and spondylolisthesis. The pedicle screw-U rod system provided more benefits in the treatment of simple lumbosacral spondylolysis, and fusion from L5 to S2 combined with S2 screw would also benefit patients with high-degree spondylolisthesis.
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Intervertebral Disc Degeneration/classification ; Intervertebral Disc Degeneration/diagnostic imaging ; Intervertebral Disc Degeneration/surgery ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Male ; Pedicle Screws ; Quality of Life ; Reproducibility of Results ; Sacrum/diagnostic imaging ; Sacrum/surgery ; Spinal Fusion/methods ; Spondylolisthesis/classification ; Spondylolisthesis/diagnostic imaging ; Spondylolisthesis/surgery ; Spondylolysis/classification ; Spondylolysis/diagnostic imaging ; Spondylolysis/surgery ; Treatment Outcome
    Language English
    Publishing date 2020-05-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.05.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Benzylic Aroylation of Toluenes Mediated by a LiN(SiMe

    Gu, Yuanyun / Zhang, Zhen / Wang, Yan-En / Dai, Ziteng / Yuan, Yaqi / Xiong, Dan / Li, Jie / Walsh, Patrick J / Mao, Jianyou

    The Journal of organic chemistry

    2021  Volume 87, Issue 1, Page(s) 406–418

    Abstract: Chemoselective deprotonative functionalization of benzylic C-H bonds is challenging, because the arene ring contains multiple aromatic C( ... ...

    Abstract Chemoselective deprotonative functionalization of benzylic C-H bonds is challenging, because the arene ring contains multiple aromatic C(sp
    Language English
    Publishing date 2021-12-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.1c02446
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Correction: Lin et al. Effect of Physical Structures of Food Matrices on Heat Resistance of

    Lin, Biying / Zhu, Yufei / Zhang, Lihui / Xu, Ruzhen / Guan, Xiangyu / Kou, Xiaoxi / Wang, Shaojin

    Foods (Basel, Switzerland)

    2021  Volume 10, Issue 8

    Abstract: The authors make the following corrections to their published paper [1] [ ... ]. ...

    Abstract The authors make the following corrections to their published paper [1] [...].
    Language English
    Publishing date 2021-07-29
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods10081751
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Caenorhabditis elegans LIN-24, a homolog of bacterial pore-forming toxin, protects the host from microbial infection.

    Zhang, Huijie / Zeng, Weirong / Zhao, Ming-Ming / Wang, Jiali / Wang, Qiquan / Chen, Ting / Zhang, Yuyan / Lee, Wenhui / Chen, Shenghan / Zhang, Yun / Lan, Xinqiang / Xiang, Yang

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    2023  Volume 37, Issue 10, Page(s) e23162

    Abstract: ... bacteria species, it remains unclear whether their anti-bacterial function is conserved. LIN-24 is an af ... that LIN-24 knockdown reduced the maximum lifespan of worms. RNA-seq analysis identified 323 differentially ... expressed genes (DEGs) post-LIN-24 knockdown that were enriched in "immune response" and "lysosome pathway ...

    Abstract Aerolysin-like pore-forming protein (af-PFP) superfamily members are double-edge swords that assist the bacterial infection but shied bacteria from the host by various mechanisms in some species including the toad Bombina maxima and zebrafish. While members of this family are widely expressed in all kingdoms, especially non-bacteria species, it remains unclear whether their anti-bacterial function is conserved. LIN-24 is an af-PFP that is constitutively expressed throughout the Caenorhabditis elegans lifespan. Here, we observed that LIN-24 knockdown reduced the maximum lifespan of worms. RNA-seq analysis identified 323 differentially expressed genes (DEGs) post-LIN-24 knockdown that were enriched in "immune response" and "lysosome pathway," suggesting a possible role for LIN-24 in resisting microbial infection. In line with this, we found that Pseudomonas aeruginosa 14 (PA14) infection induced LIN-24 expression, and that survival after PA14 infection was significantly reduced by LIN-24 knockdown. In contrast, LIN-24 overexpression (LIN-24-OE) conferred protection against PA14 infection, with worms showing longer survival time and reduced bacterial load. Weighted gene co-expression network analysis of LIN-24-OE worms showed that the highest correlation module was enriched in factors related to immunity and the defense response. Finally, by predicting transcription factors from RNA-seq data and knocking down candidate transcription factors in LIN-24-OE worms, we revealed that LIN-24 may protect worms against bacterial infection by stimulating DAF-16-mediated immune responses. These findings agree with our previous studies showing an anti-microbial role for the amphibian-derived af-PFP complex βγ-CAT, suggesting that af-PFPs may play a conserved role in combatting microbial infections. Further research is needed to determine the roles this protein family plays in other physio-pathological processes, such as metabolism, longevity, and aging.
    MeSH term(s) Animals ; Aging ; Caenorhabditis elegans/genetics ; Longevity ; Caenorhabditis elegans Proteins/genetics
    Chemical Substances perflutren (CK0N3WH0SR) ; Caenorhabditis elegans Proteins
    Language English
    Publishing date 2023-09-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639186-2
    ISSN 1530-6860 ; 0892-6638
    ISSN (online) 1530-6860
    ISSN 0892-6638
    DOI 10.1096/fj.202300063R
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2266: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 296: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Lin_F9: A Linear Empirical Scoring Function for Protein-Ligand Docking.

    Yang, Chao / Zhang, Yingkai

    Journal of chemical information and modeling

    2021  Volume 61, Issue 9, Page(s) 4630–4644

    Abstract: ... we introduce a new scoring function Lin_F9, which is a linear combination of nine empirical terms, including ... a unified metal bond term to specifically describe metal-ligand interactions. Parameters in Lin_F9 are ... benchmark test set, Lin_F9 achieves the top scoring power among all 34 classical scoring functions ...

    Abstract Molecular docking is one of the most widely used computational tools in structure-based drug design and is critically dependent on accuracy and robustness of the scoring function. In this work, we introduce a new scoring function Lin_F9, which is a linear combination of nine empirical terms, including a unified metal bond term to specifically describe metal-ligand interactions. Parameters in Lin_F9 are obtained with a multistage fitting protocol using explicit water-included structures. For the CASF-2016 benchmark test set, Lin_F9 achieves the top scoring power among all 34 classical scoring functions for both original crystal poses and locally optimized poses with Pearson correlation coefficients (
    MeSH term(s) Drug Design ; Ligands ; Molecular Docking Simulation ; Proteins ; Water
    Chemical Substances Ligands ; Proteins ; Water (059QF0KO0R)
    Language English
    Publishing date 2021-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 190019-5
    ISSN 1549-960X ; 0095-2338
    ISSN (online) 1549-960X
    ISSN 0095-2338
    DOI 10.1021/acs.jcim.1c00737
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1230: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top