LIVIVO - Search results -

Search results

Result 1 - 10 of total 514

Search options

Article ; Online: Balancing copy number in ribosomal DNA.

Malone, John H

Proceedings of the National Academy of Sciences of the United States of America

2015 Volume 112, Issue 9, Page(s) 2635–2636

MeSH term(s)	Animals ; DNA Copy Number Variations/genetics ; DNA, Ribosomal/genetics ; Female ; Genome/genetics ; Humans ; Male
Chemical Substances	DNA, Ribosomal
Language	English
Publishing date	2015-03-03
Publishing country	United States
Document type	Comment ; Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.1500054112
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Zs.A 1148: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: Widespread rescue of Y-linked genes by gene movement to autosomes.

Malone, John H

Genome biology

2015 Volume 16, Page(s) 121

Abstract: A new study provides evidence that gene transposition from sex chromosomes to autosomes is a conserved phenomenon across mammalian species that rescues dosage-sensitive genes. ...

Abstract	A new study provides evidence that gene transposition from sex chromosomes to autosomes is a conserved phenomenon across mammalian species that rescues dosage-sensitive genes.
MeSH term(s)	Animals ; Gene Deletion ; Humans ; Mammals/genetics ; Sex Chromosome Aberrations ; Translocation, Genetic ; Y Chromosome/genetics
Language	English
Publishing date	2015-06-09
Publishing country	England
Document type	Comment ; Journal Article
ZDB-ID	2040529-7
ISSN	1474-760X ; 1465-6914 ; 1465-6906
ISSN (online)	1474-760X ; 1465-6914
ISSN	1465-6906
DOI	10.1186/s13059-015-0686-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Widespread rescue of Y-linked genes by gene movement to autosomes

Malone, John H

Genome biology. 2015 Dec., v. 16, no. 1

2015

Abstract: A new study provides evidence that gene transposition from sex chromosomes to autosomes is a conserved phenomenon across mammalian species that rescues dosage-sensitive genes. ...

Abstract	A new study provides evidence that gene transposition from sex chromosomes to autosomes is a conserved phenomenon across mammalian species that rescues dosage-sensitive genes.
Keywords	autosomes ; genes ; mammals ; sex chromosomes ; transposition (genetics)
Language	English
Dates of publication	2015-12
Size	p. 121.
Publishing place	BioMed Central
Document type	Article
ZDB-ID	2040529-7
ISSN	1474-760X ; 1465-6906
ISSN (online)	1474-760X
ISSN	1465-6906
DOI	10.1186/s13059-015-0686-1
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Designing a Library of Lived Experience for Mental Health: integrated realist synthesis and experience-based co-design study in UK mental health services.

Marshall, Paul / Barbrook, John / Collins, Grace / Foster, Sheena / Glossop, Zoe / Inkster, Clare / Jebb, Paul / Johnston, Rose / Jones, Steven H / Khan, Hameed / Lodge, Christopher / Machin, Karen / Michalak, Erin / Powell, Sarah / Russell, Samantha / Rycroft-Malone, Jo / Slade, Mike / Whittaker, Lesley / Lobban, Fiona

BMJ open

2024 Volume 14, Issue 1, Page(s) e081188

Abstract: Objective: Living Library events involve people being trained as living 'Books', who then discuss aspects of their personal experiences in direct conversation with attendees, referred to as 'Readers'. This study sought to generate a realist programme ... ...

Abstract	Objective: Living Library events involve people being trained as living 'Books', who then discuss aspects of their personal experiences in direct conversation with attendees, referred to as 'Readers'. This study sought to generate a realist programme theory and a theory-informed implementation guide for a Library of Lived Experience for Mental Health (LoLEM). Design: Integrated realist synthesis and experience-based co-design. Setting: Ten online workshops with participants based in the North of England. Participants: Thirty-one participants with a combination of personal experience of using mental health services, caring for someone with mental health difficulties and/or working in mental health support roles. Results: Database searches identified 30 published and grey literature evidence sources which were integrated with data from 10 online co-design workshops conducted over 12 months. The analysis generated a programme theory comprising five context-mechanism-outcome (CMO) configurations. Findings highlight how establishing psychological safety is foundational to productive Living Library events (CMO 1). For Readers, direct conversations humanise others' experiences (CMO 2) and provide the opportunity to flexibly explore new ways of living (CMO 3). Through participation in a Living Library, Books may experience personal empowerment (CMO 4), while the process of self-authoring and co-editing their story (CMO 5) can contribute to personal development. This programme theory informed the co-design of an implementation guide highlighting the importance of tailoring event design and participant support to the contexts in which LoLEM events are held. Conclusions: The LoLEM has appeal across stakeholder groups and can be applied flexibly in a range of mental health-related settings. Implementation and evaluation are required to better understand the positive and negative impacts on Books and Readers. Trial registration number: PROSPERO CRD42022312789.
MeSH term(s)	Humans ; Mental Health ; Mental Health Services ; Empowerment ; England ; Qualitative Research
Language	English
Publishing date	2024-01-31
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-081188
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Activation of the Bile Acid Pathway and No Observed Antimicrobial Peptide Sequences in the Skin of a Poison Frog.

Civitello, Megan L / Denton, Robert / Zasloff, Michael A / Malone, John H

G3 (Bethesda, Md.)

2019 Volume 9, Issue 2, Page(s) 581–589

Abstract: The skin secretions of many frogs have genetically-encoded, endogenous antimicrobial peptides (AMPs). Other species, especially aposematic poison frogs, secrete exogenously derived alkaloids that serve as potent defense molecules. The origins of these ... ...

Abstract	The skin secretions of many frogs have genetically-encoded, endogenous antimicrobial peptides (AMPs). Other species, especially aposematic poison frogs, secrete exogenously derived alkaloids that serve as potent defense molecules. The origins of these defense systems are not clear, but a novel bile-acid derived metabolite, tauromantellic acid, was recently discovered and shown to be endogenous in poison frogs (
MeSH term(s)	Amphibian Proteins/genetics ; Amphibian Proteins/metabolism ; Animals ; Antimicrobial Cationic Peptides/genetics ; Antimicrobial Cationic Peptides/metabolism ; Anura/classification ; Anura/genetics ; Anura/metabolism ; Bile Acids and Salts/biosynthesis ; Bile Acids and Salts/genetics ; Phylogeny ; Skin/metabolism ; Transcriptome
Chemical Substances	Amphibian Proteins ; Antimicrobial Cationic Peptides ; Bile Acids and Salts
Language	English
Publishing date	2019-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2629978-1
ISSN	2160-1836 ; 2160-1836
ISSN (online)	2160-1836
ISSN	2160-1836
DOI	10.1534/g3.118.200880
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: COVID-19 Rapid Antigen Testing Implementation in California K-12 Schools.

Malone, John D / Thihalolipavan, Sayone / Bakhtar, Omid / Salamanca, Donnie / Polanco, Sherri Lynn / Taras, Howard

The Journal of school health

2022 Volume 92, Issue 12, Page(s) 1123–1127

MeSH term(s)	Humans ; COVID-19/diagnosis ; Schools ; California
Language	English
Publishing date	2022-08-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	952835-0
ISSN	1746-1561 ; 0022-4391
ISSN (online)	1746-1561
ISSN	0022-4391
DOI	10.1111/josh.13219
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Un I Zs.552: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Nonsurgical Facial Rejuvenation Procedures in Patients Under 50 Prior to Undergoing Facelift: Habits, Costs, and Results.

Jacono, Andrew A / Malone, Melanie H / Lavin, Thomas John

Aesthetic surgery journal

2017 Volume 37, Issue 4, Page(s) 448–453

Abstract: Background: Facial rejuvenation in patients younger than 50 years of age has experienced an unprecedented growth with multimodality nonsurgical and less invasive rhytidectomy techniques.: Objectives: To analyze the nonsurgical treatment habits of ... ...

Abstract	Background: Facial rejuvenation in patients younger than 50 years of age has experienced an unprecedented growth with multimodality nonsurgical and less invasive rhytidectomy techniques. Objectives: To analyze the nonsurgical treatment habits of patients prior to undergoing rhytidectomy at <50 years of age. Methods: Retrospective study to enlist patients who underwent primary rhytidectomy at age <50 years between January 1, 2003 and December 31, 2013 by the senior author (AAJ) to complete a survey. Results: One hundred and fifty-seven patients were surveyed. Patients had nonsurgical rejuvenation starting at an average age of 37 years and rhytidectomy at an average age of 44 years. Thirty-two percent of responders had injectable treatments prior to their facelift, reporting a mean of 7 rounds of injectable treatments prior to pursuing rhytidectomy. Sixteen percent of responders had laser skin resurfacing undergoing 4 separate treatments prior to rhytidectomy, and 10% had energy-based facial tightening treatments one time prior to their rhytidectomy. Average expenditure on nonsurgical treatments prior to rhytidectomy was $7000 cumulatively. Fifty-nine percent of patients who went on to rhytidectomy did not report regret over this cost expenditure. Patients reported that they appeared 4 years younger after nonsurgical intervention, and 8 years younger after their facelift, a statistically significant difference (P = .048). Conclusions: Patients undergoing rhytidectomy <50 years old begin less invasive facial rejuvenation treatments at an even earlier age. The majority of these patients did not regret the costs associated with noninvasive treatments, even though they saw that rhytidectomy provided a greater rejuvenation effect. Rhytidectomy surgeons should incorporate nonsurgical techniques into their practice to best serve the needs of the modern aging face patient.
MeSH term(s)	Adult ; Botulinum Toxins, Type A/administration & dosage ; Botulinum Toxins, Type A/economics ; Dermal Fillers/administration & dosage ; Dermal Fillers/economics ; Face/physiology ; Female ; Follow-Up Studies ; Habits ; Health Services Needs and Demand ; Humans ; Injections, Subcutaneous ; Laser Therapy/economics ; Laser Therapy/psychology ; Middle Aged ; Motivation ; Patient Satisfaction ; Rejuvenation/psychology ; Retrospective Studies ; Rhytidoplasty/methods ; Rhytidoplasty/psychology ; Skin Aging ; Surveys and Questionnaires ; Treatment Outcome
Chemical Substances	Dermal Fillers ; Botulinum Toxins, Type A (EC 3.4.24.69)
Language	English
Publishing date	2017--01
Publishing country	England
Document type	Journal Article
ZDB-ID	2087022-X
ISSN	1527-330X ; 1090-820X ; 1084-0761
ISSN (online)	1527-330X
ISSN	1090-820X ; 1084-0761
DOI	10.1093/asj/sjw217
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5721: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 570: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Room Temperature Ion Beam Synthesis of Ultra-Fine Molybdenum Carbide Nanoparticles: Toward a Scalable Fabrication Route for Earth-Abundant Electrodes.

Fiedler, Holger / Malone, Niall / Mitchell, David R G / Nancarrow, Mitchell / Jovic, Vedran / Waterhouse, Geoffrey I N / Kennedy, John / Gupta, Prasanth

Small (Weinheim an der Bergstrasse, Germany)

2023 , Page(s) e2304118

Abstract: Molybdenum carbides are promising low-cost electrocatalysts for electrolyzers, fuel cells, and batteries. However, synthesis of ultrafine, phase-pure carbide nanoparticles (diameter < 5 nm) with large surface areas remains challenging due to ... ...

Abstract	Molybdenum carbides are promising low-cost electrocatalysts for electrolyzers, fuel cells, and batteries. However, synthesis of ultrafine, phase-pure carbide nanoparticles (diameter < 5 nm) with large surface areas remains challenging due to uncontrollable agglomeration that occurs during traditional high temperature syntheses. This work presents a scalable, physical approach to synthesize molybdenum carbide nanoparticles at room temperature by ion implantation. By tuning the implantation conditions, various molybdenum carbide phases, stoichiometries, and nanoparticle sizes can be accessed. For instance, molybdenum ion implantation into glassy carbon at 30 keV energy and to a fluence of 9 × 10
Language	English
Publishing date	2023-07-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202304118
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The use of a new high-speed shielded curved drill is associated with improved intraoperative and clinical outcomes after cervical corpectomy and fusion procedures: a retrospective case series.

Peloza, John / Malone, Hani / Jacobian, Erel / Kolsky, Daniel E / Harel, Ran / Guyer, Richard D / Millgram, Michael A / Ashkenazi, Ely

Journal of orthopaedic surgery and research

2023 Volume 18, Issue 1, Page(s) 364

Abstract: Background: Anterior cervical corpectomy and fusion (ACCF) is an effective technique to address multi-level degenerative cervical myelopathy. However, as the number of surgical levels increases, the outcomes worsen with respect to complication rates, ... ...

Abstract	Background: Anterior cervical corpectomy and fusion (ACCF) is an effective technique to address multi-level degenerative cervical myelopathy. However, as the number of surgical levels increases, the outcomes worsen with respect to complication rates, range of motion and length of surgery. This study aimed to determine the clinical outcome of ACCF procedures performed using a new distally curved and shielded drilling device. Methods: A retrospective study was conducted on 43 ACCF procedures in which the device was used for osteophyte removal. Patient files were reviewed to assess the early clinical results and complications following ACCF. Clinical outcomes were evaluated using patient neck and arm pain scores and SF-36 questionnaires. Hospitalization characteristics were compared with historical controls. Results: All procedures were uneventful and without major complications or neurological deterioration. Single-level ACCF procedures required an average of 71 min and followed by an average hospitalization of 3.3 days. Osteophyte removal, verified by intraoperative imaging, was satisfactory. Average neck pain score was improved by 0.9 points (p = 0.24). Average arm pain score was improved by 1.8 points (p = 0.06). SF-36 scores were improved in all domains. Conclusions: The new curved device enabled safe and efficient removal of osteophytes sparing adjacent vertebral removal in ACCF procedures, thus improving the clinical outcome.
MeSH term(s)	Humans ; Retrospective Studies ; Treatment Outcome ; Osteophyte ; Spondylosis/diagnostic imaging ; Spondylosis/surgery ; Spondylosis/complications ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Diskectomy/adverse effects ; Diskectomy/methods ; Neck Pain/etiology ; Neck Pain/surgery ; Spinal Fusion/methods
Language	English
Publishing date	2023-05-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2252548-8
ISSN	1749-799X ; 1749-799X
ISSN (online)	1749-799X
ISSN	1749-799X
DOI	10.1186/s13018-023-03769-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Designing a library of lived experience for mental health (LoLEM): protocol for integrating a realist synthesis and experience based codesign approach.

Lobban, Fiona / Marshall, Paul / Barbrook, John / Collins, Grace / Foster, Sheena / Glossop, Zoe / Inkster, Clare / Jebb, Paul / Johnston, Rose / Khan, Hameed / Lodge, Christopher / Machin, Karen / Michalak, Erin / Powell, Sarah / Rycroft-Malone, Jo / Slade, Mike / Whittaker, Lesley / Jones, Steven H

BMJ open

2023 Volume 13, Issue 3, Page(s) e068548

Abstract: Introduction: People with lived expertise in managing mental health challenges can be an important source of knowledge and support for other people facing similar challenges, and for carers to learn how best to help. However, opportunities for sharing ... ...

Abstract	Introduction: People with lived expertise in managing mental health challenges can be an important source of knowledge and support for other people facing similar challenges, and for carers to learn how best to help. However, opportunities for sharing lived expertise are limited. Living libraries support people with lived expertise to be 'living books', sharing their experiences in dialogue with 'readers' who can ask questions. Living libraries have been piloted worldwide in health-related contexts but without a clear model of how they work or rigorous evaluation of their impacts. We aim to develop a programme theory about how a living library could be used to improve mental health outcomes, using this theory to codesign an implementation guide that can be evaluated across different contexts. Methods and analysis: We will use a novel integration of realist synthesis and experience-based codesign (EBCD) to produce a programme theory about how living libraries work and a theory and experience informed guide to establishing a library of lived experience for mental health (LoLEM). Two workstreams will run concurrently: (1) a realist synthesis of literature on living libraries, combined with stakeholder interviews, will produce several programme theories; theories will be developed collaboratively with an expert advisory group of stakeholders who have hosted or taken part in a living library and will form our initial analysis framework; a systematic search will identify literature about living libraries; data will be coded into our analysis framework, and we will use retroductive reasoning to explain living libraries' impacts across multiple contexts. Individual stakeholder interviews will help refine and test theories; (2) data from workstream 1 will inform 10 EBCD workshops with people with experience of managing mental health difficulties and health professionals to produce a LoLEM implementation guide; data from this process will also inform the theory in workstream 1. Ethics and dissemination: Ethical approval was granted by Coventry and Warwick National Health Service Research Ethics Committee on 29 December 2021 (reference number 305975). The programme theory and implementation guide will be published as open access and shared widely through a knowledge exchange event, a study website, mental health provider and peer support networks, peer reviewed journals and a funders report. Prospero registration details: CRD42022312789.
MeSH term(s)	Humans ; Mental Health ; State Medicine ; Problem Solving ; Learning
Language	English
Publishing date	2023-03-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-068548
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito