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Article ; Online: Adherence to Asthma Treatments: An Audit of a Warehouse of Data.

Sulaiman, Imran / Costello, Richard W

2021 Volume 159, Issue 3, Page(s) 891–892

MeSH term(s)	Asthma/drug therapy ; Guideline Adherence ; Humans
Language	English
Publishing date	2021-03-07
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1016/j.chest.2020.12.023
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Ui III Zs.45: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 349: Show issues

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Article ; Online: The role of the respiratory microbiome in asthma.

Campbell, Christina D / Gleeson, Margaret / Sulaiman, Imran

Frontiers in allergy

2023 Volume 4, Page(s) 1120999

Abstract: Asthma is a common airways disease and the human microbiome plays an increasingly recognised role in asthma pathogenesis. Furthermore, the respiratory microbiome varies with asthma phenotype, endotype and disease severity. Consequently, asthma therapies ... ...

Abstract	Asthma is a common airways disease and the human microbiome plays an increasingly recognised role in asthma pathogenesis. Furthermore, the respiratory microbiome varies with asthma phenotype, endotype and disease severity. Consequently, asthma therapies have a direct effect on the respiratory microbiome. Newer biological therapies have led to a significant paradigm shift in how we treat refractory Type 2 high asthma. While airway inflammation is the generally accepted mechanism of action of all asthma therapies, including both inhaled and systemic therapies, there is evidence to suggest that they may also alter the microbiome to create a more functionally balanced airway microenvironment while also influencing airway inflammation directly. This downregulated inflammatory cascade seen biochemically, and reflected in improved clinical outcomes, supports the hypothesis that biological therapies may in fact affect the microbiome-host immune system dynamic and thus represent a therapeutic target for exacerbations and disease control.
Language	English
Publishing date	2023-05-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ISSN	2673-6101
ISSN (online)	2673-6101
DOI	10.3389/falgy.2023.1120999
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Article: A clinicians' review of the respiratory microbiome.

Campbell, Christina D / Barnett, Clea / Sulaiman, Imran

Breathe (Sheffield, England)

2022 Volume 18, Issue 1, Page(s) 210161

Abstract: The respiratory microbiome and its impact in health and disease is now well characterised. With the development of next-generation sequencing and the use of other techniques such as metabolomics, the functional impact of microorganisms in different host ... ...

Abstract	The respiratory microbiome and its impact in health and disease is now well characterised. With the development of next-generation sequencing and the use of other techniques such as metabolomics, the functional impact of microorganisms in different host environments can be elucidated. It is now clear that the respiratory microbiome plays an important role in respiratory disease. In some diseases, such as bronchiectasis, examination of the microbiome can even be used to identify patients at higher risk of poor outcomes. Furthermore, the microbiome can aid in phenotyping. Finally, development of multi-omic analysis has revealed interactions between the host and microbiome in some conditions. This review, although not exhaustive, aims to outline how the microbiome is investigated, the healthy respiratory microbiome and its role in respiratory disease. Educational aims: To define the respiratory microbiome and describe its analysis.To outline the respiratory microbiome in health and disease.To describe future directions for microbiome research.
Language	English
Publishing date	2022-04-05
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2562899-9
ISSN	2073-4735 ; 1810-6838
ISSN (online)	2073-4735
ISSN	1810-6838
DOI	10.1183/20734735.0161-2021
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Article ; Online: Zinc Vanadate (Zn

Alharthi, Fahad A / Ababtain, Alanood Sulaiman / Alanazi, Hamdah S / Alshayiqi, Alanoud Abdullah / Hasan, Imran

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 3

Abstract: Z-scheme photocatalytic reaction is considered an effective strategy to promote the photogenerated electron-hole separation for significantly improving the efficiency of photocatalytic hydrogen precipitation from splitting water. In this study, a ... ...

Abstract	Z-scheme photocatalytic reaction is considered an effective strategy to promote the photogenerated electron-hole separation for significantly improving the efficiency of photocatalytic hydrogen precipitation from splitting water. In this study, a heterojunction nanocomposite material based on Zn
Language	English
Publishing date	2023-01-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28031362
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Article ; Online: Analysis of dataset on reduction of high temperature stress by green net shade alleviate oxidative stress and augments the growth and vase life of gladiolus cut flower.

Qayyum, Muhammad Mazhar / Hassan, Imran / Khan, Shah Masaud / Subhan, Mishal / Saleem, Shahzad / Fiaz, Sajid / Alharbi, Sulaiman Ali / Ansari, Mohammad Javed

Data in brief

2024 Volume 54, Page(s) 110378

Abstract: The study was conducted to investigate the effect of green net shade during staggered planting times on growth, biochemical, antioxidant enzymes and vase life of gladiolus cut flowers. The green net shade effectively reduces the internal temperature, ... ...

Abstract	The study was conducted to investigate the effect of green net shade during staggered planting times on growth, biochemical, antioxidant enzymes and vase life of gladiolus cut flowers. The green net shade effectively reduces the internal temperature, particularly during extremely hot planting times. Under the green net shade conditions, high quality morphological and biochemical observations were observed during the months of March and April planting times. These included longer plant height, spike length, a higher number of leaves plant
Language	English
Publishing date	2024-04-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2786545-9
ISSN	2352-3409 ; 2352-3409
ISSN (online)	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2024.110378
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Article ; Online: Developing a Conceptual Framework Model for Effective Perishable Food Cold-Supply-Chain Management Based on Structured Literature Review

Hafiz Wasim Akram / Samreen Akhtar / Alam Ahmad / Imran Anwar / Mohammad Ali Bait Ali Sulaiman

Sustainability, Vol 15, Iss 4907, p

2023 Volume 4907

Abstract: This paper reviews the literature on perishable food cold-chain management (FCCM) in order to assess its current state, pinpoint its knowledge gaps, and suggest a framework for addressing the issues faced by this industry. This work examines 103 academic ...

Abstract	This paper reviews the literature on perishable food cold-chain management (FCCM) in order to assess its current state, pinpoint its knowledge gaps, and suggest a framework for addressing the issues faced by this industry. This work examines 103 academic articles on the topic of the perishable food supply chain published in various journals between 2001 and 2022. Research publications were selected from two reputed databases—Scopus and Web of Science. The study finds that the current trend in FCCM is toward sustainable FCCM, which offers financial, ecological, and social benefits. However, sustainable FCC practices are more common in wealthy nations but are still lacking in developing countries. High lead times, costs, waste, order returns, complaints, and dissatisfied consumers are the results of a fragmented market and the associated proliferation of chain intermediates. The authors have also developed a conceptual framework based on the findings that illustrates the interconnected nature of the food cold-chain facilities, collaboration among food cold-chain (FCC) stakeholders, concern among FCC stakeholders, economic enhancement, fulfilment of FCC stakeholders’ responsibilities, and overall functioning of the FCC. This study may be helpful to FCC professionals, food regulators, government authorities, and researchers because it gives a concise picture of the state of research in the field.
Keywords	food cold-chain ; cold-chain performance ; cold supply chain ; sustainable food supply chain ; perishable food supply chain ; food traders ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Zinc Vanadate (Zn 3 V 2 O 8 ) Immobilized Multiwall Carbon Nanotube (MWCNT) Heterojunction as an Efficient Photocatalyst for Visible Light Driven Hydrogen Production

Fahad A. Alharthi / Alanood Sulaiman Ababtain / Hamdah S. Alanazi / Alanoud Abdullah Alshayiqi / Imran Hasan

Molecules, Vol 28, Iss 1362, p

2023 Volume 1362

Abstract	Z-scheme photocatalytic reaction is considered an effective strategy to promote the photogenerated electron-hole separation for significantly improving the efficiency of photocatalytic hydrogen precipitation from splitting water. In this study, a heterojunction nanocomposite material based on Zn 3 V 2 O 8 (ZV) with MWCNT was prepared by a hydrothermal process. The photocatalysts were characterized by X-ray diffraction, scanning electron microscopy (SEM), Fourier transform infrared (FTIR), UV-visible absorption spectroscopy, and transmission electron microscopy (TEM) to understand crystal structure, morphology, and optical properties. The efficiency of the samples was evaluated for the photocatalytic H 2 production under visible solar radiation using water glycerol as a sacrificial reagent. The obtained results suggest that, between ZV and ZV@MWCNT, the latter shows higher efficiency for H 2 production. The maximum H 2 production efficiency was found to be 26.87 μmol g −1 h −1 for ZV and 99.55 μmol g −1 h −1 for ZV@MWCNT. The synergistic effect of MWCNT to ZV resulted in improving the efficiency of charges and light-absorbing capacity, resulting in enhanced H 2 production in the heterojunction nanocomposite material. The nanocomposite was stable and highly efficient for H 2 production of six or more cycles. Based on the outcomes of this study, it can be observed that forming the heterojunction of individual nano systems could result in more efficient material for H 2 production under visible solar energy.
Keywords	MWCNT ; Nanocomposites ; H 2 evolution ; heterojunction ; photocatalytic process ; Organic chemistry ; QD241-441
Subject code	290
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Synthesis of Novel Zn 3 V 2 O 8 /Ag Nanocomposite for Efficient Photocatalytic Hydrogen Production

Fahad A. Alharthi / Alanood Sulaiman Ababtain / Hend Khalid Aldubeikl / Hamdah S. Alanazi / Imran Hasan

Catalysts, Vol 13, Iss 455, p

2023 Volume 455

Abstract: In this study, we fabricated Zn 3 V 2 O 8 and a Ag-modified Zn 3 V 2 O 8 composite (Zn 3 V 2 O 8 /Ag) by utilizing effective and benign approaches. Further characterization techniques such as powder X-ray diffraction (XRD) and scanning electron ... ...

Abstract	In this study, we fabricated Zn 3 V 2 O 8 and a Ag-modified Zn 3 V 2 O 8 composite (Zn 3 V 2 O 8 /Ag) by utilizing effective and benign approaches. Further characterization techniques such as powder X-ray diffraction (XRD) and scanning electron microscopy (SEM) were explored to examine the phase and structural properties, respectively, of the synthesized Zn 3 V 2 O 8 /Ag and Zn 3 V 2 O 8 /Ag composite materials. The oxidation states and elemental composition of the synthesized Zn 3 V 2 O 8 /Ag and Zn 3 V 2 O 8 /Ag were characterized by adopting X-ray photoelectron spectroscopy (XPS) and energy-dispersive X-ray spectroscopy (EDX). The optical band gaps of the synthesized Zn 3 V 2 O 8 /Ag and Zn 3 V 2 O 8 /Ag were examined by employing ultraviolet–visible (UV-vis) diffuse reflection spectroscopy. HRTEM images clearly show that ZnV@Ag NC has a hexagonal plate-like morphology. Subsequently, Zn 3 V 2 O 8 and Zn 3 V 2 O 8 /Ag were used as photocatalysts for photocatalytic hydrogen (H 2 ) production. It was observed that after Ag doping, the energy band gap of ZnV was reduced from 2.33 eV to 2.19 eV. EDX mapping images also show the presence of Ag, O, Zn, and V elements and confirm the formation of ZnV@Ag NC with good phase purity. Observations clearly showed the presence of excellent photocatalytic properties of the synthesized photocatalyst. The Zn 3 V 2 O 8 /Ag photocatalyst exhibited H 2 generation of 37.52 µmolg −1 h −1 , which is higher compared to pristine Zn 3 V 2 O 8 . The Zn 3 V 2 O 8 /Ag photocatalyst also demonstrated excellent reusability, including decent stability. The reusability experiments suggested that ZnV@Ag NC has excellent cyclic stability for up to six cycles.
Keywords	Zn 3 V 2 O 8 /Ag nanocomposite ; photocatalytic H 2 production ; water splitting ; surface plasmon resonance ; sacrificial reagents ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Overcoming chemoresistance and radio resistance in prostate cancer: The emergent role of non-coding RNAs.

Sarfraz, Muhammad / Abida / Eltaib, Lina / Asdaq, Syed Mohammed Basheeruddin / Guetat, Arbi / Alzahrani, A Khuzaim / Alanazi, Shatha Sulaiman / Aaghaz, Shams / Singla, Neelam / Imran, Mohd

Pathology, research and practice

2024 Volume 255, Page(s) 155179

Abstract: Prostate cancer (PCa) continues to be a major health concern worldwide, with its resistance to chemotherapy and radiation therapy presenting major hurdles in successful treatment. While patients with localized prostate cancer generally have a good ... ...

Abstract	Prostate cancer (PCa) continues to be a major health concern worldwide, with its resistance to chemotherapy and radiation therapy presenting major hurdles in successful treatment. While patients with localized prostate cancer generally have a good survival rate, those with metastatic prostate cancer often face a grim prognosis, even with aggressive treatments using various methods. The high mortality rate in severe cases is largely due to the lack of treatment options that can offer lasting results, especially considering the significant genetic diversity found in tumors at the genomic level. This comprehensive review examines the intricate molecular mechanisms governing resistance in PCa, emphasising the pivotal contributions of non-coding RNAs (ncRNAs). We delve into the diverse roles of microRNAs, long ncRNAs, and other non-coding elements as critical regulators of key cellular processes involved in CR & RR. The review emphasizes the diagnostic potential of ncRNAs as predictive biomarkers for treatment response, offering insights into patient stratification and personalized therapeutic approaches. Additionally, we explore the therapeutic implications of targeting ncRNAs to overcome CR & RR, highlighting innovative strategies to restore treatment sensitivity. By synthesizing current knowledge, this review not only provides a comprehension of the chemical basis of resistance in PCa but also identifies gaps in knowledge, paving the way for future research directions. Ultimately, this exploration of ncRNA perspectives offers a roadmap for advancing precision medicine in PCa, potentially transforming therapeutic paradigms and improving outcomes for patients facing the challenges of treatment resistance.
MeSH term(s)	Male ; Humans ; Drug Resistance, Neoplasm/genetics ; RNA, Untranslated/genetics ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/diagnosis
Chemical Substances	RNA, Untranslated ; MicroRNAs ; RNA, Long Noncoding
Language	English
Publishing date	2024-02-01
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	391889-0
ISSN	1618-0631 ; 0344-0338
ISSN (online)	1618-0631
ISSN	0344-0338
DOI	10.1016/j.prp.2024.155179
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Article ; Online: In silico

Awan, Zuhier A / Khan, Haider Ali / Jamal, Alam / Shams, Sulaiman / Zheng, Guojun / Wadood, Abdul / Shahab, Muhammad / Khan, Mohammad Imran / Kalantan, Abdulaziz A

Journal of biomolecular structure & dynamics

2024 , Page(s) 1–11

Abstract: Inhibitors of α-glucosidase have been used to treat type-2 diabetes (T2DM) by preventing the breakdown of carbohydrates into glucose and prevent enhancing glucose conversion. Structure-based virtual screening (SBVS) was used to generate novel chemical ... ...

Abstract	Inhibitors of α-glucosidase have been used to treat type-2 diabetes (T2DM) by preventing the breakdown of carbohydrates into glucose and prevent enhancing glucose conversion. Structure-based virtual screening (SBVS) was used to generate novel chemical scaffold-ligand α-glucosidase inhibitors. The databases were screened against the receptor α-glucosidase using SBVS and molecular dynamics simulation (MDS) techniques in this study. Based on molecular docking studies, three and two compounds of α-glucosidase inhibitors were chosen from a commercial database (ZINC) and an In-house database for this study respectively. The mode of binding interactions of the selected compounds later predicted their α-glucosidase inhibitory potential. Finally, one out of three lead compound from ZINC and one out of two lead compound from In-house database were shortlisted based on interactions. Furthermore, MDS and post-MDS strategies were used to refine and validate the shortlisted leads along with the reference acarbose/α-glucosidase. The Hits' ability to inhibit α-glucosidase was predicted by SBVS, indicating that these compounds have good inhibitory activities. The lead inhibitor's structure may serve as templates for the design of novel inhibitors, and
Language	English
Publishing date	2024-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2023.2298391
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