Article ; Online: What Should I Eat? Dietary Recommendations for Patients with Inflammatory Bowel Disease.
2023 Volume 15, Issue 4
Abstract: Inflammatory bowel disease (IBD) is a chronic disorder thought to be caused by enteric inflammation in a genetically susceptible host. Although the pathogenesis of IBD is largely unknown, it is widely accepted that dietary components play an important ... ...
| Abstract | Inflammatory bowel disease (IBD) is a chronic disorder thought to be caused by enteric inflammation in a genetically susceptible host. Although the pathogenesis of IBD is largely unknown, it is widely accepted that dietary components play an important role. Human and animal-based studies have explored the role of various dietary components such as meat, artificial sweeteners and food additives in causing enteric inflammation. Several diets have also been studied in patients with IBD, specifically their role in the induction or maintenance of remission. The most well-studied of these include exclusive enteral nutrition and specific carbohydrate diet. A diet low in FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides and polyols), typically prescribed for patients with irritable bowel syndrome, has also been studied in a specific subgroup of patients with IBD. In this review, we describe the current evidence on how various dietary components can induce enteric and colonic inflammation, and the clinical-epidemiological evidence exploring their role in predisposing to or protecting against the development of IBD. We also discuss several special diets and how they affect clinical outcomes in IBD patients. Based on the available evidence, we provide guidance for patients and clinicians managing IBD regarding the best practice in dietary modifications. |
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| MeSH term(s) | Animals ; Humans ; Inflammatory Bowel Diseases/chemically induced ; Diet/adverse effects ; Oligosaccharides/adverse effects ; Disaccharides/adverse effects ; Inflammation/chemically induced ; Monosaccharides/adverse effects |
| Chemical Substances | Oligosaccharides ; Disaccharides ; Monosaccharides |
| Language | English |
| Publishing date | 2023-02-10 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Review |
| ZDB-ID | 2518386-2 |
| ISSN | 2072-6643 ; 2072-6643 |
| ISSN (online) | 2072-6643 |
| ISSN | 2072-6643 |
| DOI | 10.3390/nu15040896 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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