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  1. Article: Protective effect of coenzyme Q10 against doxorubicin-induced cardiotoxicity: Scoping review article.

    Qahtani Abdullah, Al / Balawi Hamed, Al / Jowesim Fahad, Al

    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

    2023  Volume 32, Issue 2, Page(s) 101882

    Abstract: Introduction: Doxorubicin (dox) is classified as an antineoplastic antibiotic which is known as adriamycin from the anthracycline group. Due to the release of free radicals and lipid peroxidation which can cause acute cardiotoxicity. Coenzyme Q10 is ... ...

    Abstract Introduction: Doxorubicin (dox) is classified as an antineoplastic antibiotic which is known as adriamycin from the anthracycline group. Due to the release of free radicals and lipid peroxidation which can cause acute cardiotoxicity. Coenzyme Q10 is found in many cells of the body, it is an antioxidant that reduces oxidative stress and lipid peroxidation.
    Aim: This scoping review aims to evaluate the cardioprotective effect of coenzyme Q10 in doxorubicin-induced cardiotoxicity in animals.
    Methods: This review was done based on Arksey and O'Malley's methodology, reviewing published articles from October 1978 and September 2023.
    Results: 14 out of 11,303 articles were included from the initial search, (10 out of 14 articles found that coenzyme Q10 protect has a protection effect against doxorubicin-induced cardiotoxicity).
    Conclusion: The results of this review found coenzyme Q10 protects against doxorubicin cardiotoxicity. It is a promising supplement that could be used to prevent cardiotoxicity induced by doxorubicin in cancer patients.
    Language English
    Publishing date 2023-11-21
    Publishing country Saudi Arabia
    Document type Journal Article ; Review
    ZDB-ID 1378024-4
    ISSN 1319-0164
    ISSN 1319-0164
    DOI 10.1016/j.jsps.2023.101882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4758: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Microdroplets are more infectious of COVID-19 spread in a closed door.

    Al Qahtani, Fahad / Al Qahtani, Modi Fahd / Al Qahtani, Ahad Fahd / Bhat, Nagesh

    Journal of family medicine and primary care

    2020  Volume 9, Issue 7, Page(s) 3776–3777

    Keywords covid19
    Language English
    Publishing date 2020-07-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_526_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Robust FOSMC of quadrotor in the presence of slung load.

    Ferik, Sami El / Al-Qahtani, Fahad M / Saif, Abdul-Wahid A / Al-Dhaifallah, Mujahed

    ISA transactions

    2023  Volume 139, Page(s) 106–121

    Abstract: This study aims to develop a robust control for the quadrotor slung-load system that efficiently follows a reference trajectory. A fractional-order robust sliding mode control has been chosen to control the quadrotor's altitude, position, and attitude. ... ...

    Abstract This study aims to develop a robust control for the quadrotor slung-load system that efficiently follows a reference trajectory. A fractional-order robust sliding mode control has been chosen to control the quadrotor's altitude, position, and attitude. An anti-swing controller was also installed to limit the swing angle of the suspended load. It was created via delayed feedback, in which the quadrotor's position reference trajectory is changed by the difference of the load angles within a specific delayed value. Designing an adaptive FOSMC would control the system when the system uncertainties do not know the bounds. Moreover, the control parameters and the anti-swing controller for the FOSMC can be obtained using some optimization techniques to increase the controllers' accuracy.
    Language English
    Publishing date 2023-04-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2023.04.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Microdroplets are more infectious of COVID-19 spread in a closed door

    Fahad Al Qahtani / Modi Fahd Al Qahtani / Ahad Fahd Al Qahtani / Nagesh Bhat

    Journal of Family Medicine and Primary Care, Vol 9, Iss 7, Pp 3776-

    2020  Volume 3777

    Keywords Medicine ; R ; covid19
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells.

    Al-Qahtani, Salwa D / Bin-Melaih, Hawazen H / Atiya, Eman M / Fahmy, Usama A / Binmahfouz, Lenah S / Neamatallah, Thikryat / Al-Abbasi, Fahad A / Abdel-Naim, Ashraf B

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 6

    Abstract: In the original publication [ ... ]. ...

    Abstract In the original publication [...].
    Language English
    Publishing date 2023-06-08
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13061343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Microdroplets are more infectious of COVID-19 spread in a closed door

    Bhat, Nagesh / Al Qahtani, Fahad / Al Qahtani, ModiFahd / Al Qahtani, AhadFahd

    Journal of Family Medicine and Primary Care

    2020  Volume 9, Issue 7, Page(s) 3776

    Keywords covid19
    Language English
    Publisher Medknow
    Publishing country in
    Document type Article ; Online
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_526_20
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article: Transcatheter Mitral Valve Repair with MitraClip

    Al-Asmi, Shabib Abdulah / Kaddoura, Rasha / Abdelghani, Mohammed Salah / Ahmed, Ashraf / Maaly, Cheik Abdoul / Alzaeem, Hakam / Mohammed, Nazar / Shehadeh, Mohanad / Al-Kindi, Fahad Abdullah / Al-Qahtani, Awad / Al-Hijji, Mohammed

    Heart views : the official journal of the Gulf Heart Association

    2023  Volume 24, Issue 4, Page(s) 179–187

    Abstract: Background: Transcatheter mitral valve repair (TMVr), using MitraClip: Conclusion: The TMVr procedure using the ... ...

    Abstract Background: Transcatheter mitral valve repair (TMVr), using MitraClip
    Conclusion: The TMVr procedure using the MitraClip
    Language English
    Publishing date 2023-11-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 2575257-1
    ISSN 0976-5123 ; 1995-705X
    ISSN (online) 0976-5123
    ISSN 1995-705X
    DOI 10.4103/heartviews.heartviews_90_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Assessment of Parental Knowledge, Awareness, and Perception About Autism Spectrum Disorders in Aseer Region, Southwestern Saudi Arabia.

    AlAlmaei Asiri, Waddah M / Shati, Ayed A / Al-Qahtani, Saleh M / Al-Qahtani, Youssef A / Aldarami, Mohammed S / Alamri, Fahad D / Alshahrani, Huda S / Esam Mahmood, Syed

    International journal of general medicine

    2023  Volume 16, Page(s) 557–564

    Abstract: Background: Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects young children in social relatedness and communication besides other characteristics. A community's awareness and early intervention services in diagnosing and ... ...

    Abstract Background: Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects young children in social relatedness and communication besides other characteristics. A community's awareness and early intervention services in diagnosing and treating autistic children are essential for preventing the expected complications, eg language delay, social interaction, and intellectual ability.
    Aim: To assess the parent's knowledge and perceptions regarding autism and its associated clinical features and effects.
    Methodology: A cross-sectional study was conducted targeting all available parents aged 18 years or more living in Aseer region. Data were collected using a self-reported questionnaire from randomly selected parents who attended outpatient clinics at Abha Maternity and Children Hospital and Aseer Central Hospital. Parents' knowledge regarding autism was assessed covering general knowledge, clinical features, social effects, consequences, and curability.
    Results: A total of 477 parents participated. Parents' ages ranged from 18 to 85 years. 261 (54.7%) parents were male and 216 (45.3%) were females. Nearly 65.6% of parents were university graduates and 28.3% had a secondary level of education. About 50.9% of the parents know that genetics play a major role in causing autism, 69.6% think that most children with autism have special talents or abilities, 64.2% know that delayed language development is one of the main symptoms of autism, 61.2% also know that repetitive movements of the hands and head are a common symptom of autism. About 36.9% of parents think that diagnosing a child with autism will lead to discrimination against the child, 33.3% of parents think that autism is a rare condition in this country compared to the West.
    Conclusion: The study showed that parents had poor knowledge levels regarding autism and its related clinical features, especially male parents with low levels of education. On the other hand, their perception of the disease and its frequency in the study area was satisfactory.
    Language English
    Publishing date 2023-02-16
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S377521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Promoting Dental Health Through Teledentistry: Assessing Awareness and Attitudes in Saudi Arabia.

    Alhur, Anas / Al Shahrani, Faisal / Alasiri, Khlood / Almutairi, Nourah / Almadi, Sarrah / Alfazae, Sami / Alqahtani, Mohammed / Aljehani, Mashael / Alqarni, Mohammed / Al Qahtani, Abdullah / Alzahrani, Fahad / Almaymuni, Bandar / Al Qobti, Rahaif

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55805

    Abstract: Introduction Teledentistry has emerged as a promising solution to enhance dental healthcare accessibility and quality. Understanding public awareness and attitudes toward teledentistry is crucial for its successful implementation, especially in regions ... ...

    Abstract Introduction Teledentistry has emerged as a promising solution to enhance dental healthcare accessibility and quality. Understanding public awareness and attitudes toward teledentistry is crucial for its successful implementation, especially in regions like Saudi Arabia where digital health initiatives are rapidly expanding. This study aims to assess the level of awareness, attitudes, and perceptions toward teledentistry among the Saudi Arabian population, as well as examine the demographic factors influencing its acceptance. Methods A cross-sectional survey was conducted with 474 participants, employing a structured questionnaire to collect data on demographics, awareness, knowledge, perceptions, and attitudes toward teledentistry. Statistical analyses, including correlation and chi-square tests, were performed to analyze the data. Results The majority of respondents (64%) reported awareness of teledentistry, primarily through the Internet (44.5%) and healthcare providers (36.3%). The average self-assessed knowledge score was 3.04 out of 5, indicating moderate familiarity with teledentistry concepts. Attitudes toward teledentistry were generally positive, with 54% expressing belief in its effectiveness. However, a significant portion of the sample showed reluctance toward using teledentistry for routine dental check-ups, with only 45.1% showing willingness. High technological accessibility was reported, yet 55.9% of participants preferred traditional in-person consultations. Correlation analysis revealed a moderate positive relationship between knowledge and belief in effectiveness (r = 0.21), but a negligible correlation with willingness to use teledentistry (r = 0.016). A strong positive correlation was found between belief in effectiveness and willingness for routine check-ups (r = 0.673). Educational level significantly influenced teledentistry acceptance, with higher education correlating with greater receptiveness. Conclusion While there is a moderate level of awareness and a generally positive attitude toward teledentistry among the Saudi population, hesitance remains regarding its use for routine care. The findings highlight the need for educational initiatives to improve knowledge and perceptions of teledentistry, potentially enhancing its acceptance and integration into the healthcare system.
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A Selective Gas Chromatography-Tandem Mass Spectrometry Method for Quantitation of Ethylene and Diethylene Glycol in Paediatric Syrups.

    Altamimy, Monerah A / Alshehri, Yahya M / Aldawsari, Fahad S / Altalyan, Norah H / AlShmmari, Sultan K / Alzaid, Shaikah F / Al-Qahtani, Naif A / Alsagoor, Turki M / Al Shahrani, Mobarak S

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e27559

    Abstract: Ethylene Glycol (EG) and diethylene Glycol (DEG) are two contaminants known to cause various human health problems. These glycols might be present in drug syrups that are based on glycerol, sorbitol, or polyethylene glycol. In late 2022, several batches ... ...

    Abstract Ethylene Glycol (EG) and diethylene Glycol (DEG) are two contaminants known to cause various human health problems. These glycols might be present in drug syrups that are based on glycerol, sorbitol, or polyethylene glycol. In late 2022, several batches of cough, antipyretics, and antihistamine syrups were reported to contain toxic levels of EG and DEG in multiple countries; this incident concerned the World Health Organization (WHO). From an analytical perspective, several methods of glycols analysis in pharmaceuticals have been reported in the literature, with the majority being dedicated to raw material analysis. This study aims to develop a selective method capable of evaluating a wide range of paediatric syrups in order to assess the safety of commercially available paediatric syrups currently distributed in the local market. This research introduces a method for determining glycols utilizing gas chromatography-tandem mass spectrometry (GC-MS/MS), which offers significantly higher selectivity than conventional single quadrupole gas chromatography-mass spectrometry (GC-MS). The developed method meets the current International Council for Harmonisation (ICH) guidelines for validation. The absence of any interfering peaks in both the unspiked sample of promethazine syrup and the reference standard solutions proved the method's selectivity. Furthermore, 2,2,2-trichloroethanol was used as an internal standard, and a new GC-MS/MS method was developed to analyze it. The calibration curves for EG and DEG were linear within the selected concentration range of 1-10 μg/mL. The detection limit for both EG and DEG was 400 ng/mL, while the quantification limit was 1 μg/mL. Recovery values for both EG and DEG met the accuracy acceptance criterion. Thus, the developed method proved to be efficient and accurate for determining EG and DEG levels in suspected contaminated syrups.
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e27559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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