Article ; Online: Viral evolution and epidemiology.
Current opinion in infectious diseases
2015 Volume 10, Issue 5, Page(s) 367–371
Abstract: This review highlights recent research on viral evolution and its use towards understanding disease pathogenesis and epidemiology. The development of techniques such as enzymatic amplification of viral genomes and automated sequencing has led to a ... ...
Abstract | This review highlights recent research on viral evolution and its use towards understanding disease pathogenesis and epidemiology. The development of techniques such as enzymatic amplification of viral genomes and automated sequencing has led to a dramatic increase in the amount of sequence information from clinical samples. These sequences (RNA or DNA, or the amino acids they encode) have been compared by complex computer algorithms to generate evolutionary trees or phylogenies of natural virus variants, which can sometimes be used to correlate viral genotype with phenotype. Understanding the rates and types of evolution that occur during the transmission of viruses has considerable impact on the design of methods for the control of virus diseases. |
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Language | English |
Publishing date | 2015-08-09 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 645085-4 |
ISSN | 1473-6527 ; 1535-3877 ; 0951-7375 ; 1355-834X |
ISSN (online) | 1473-6527 ; 1535-3877 |
ISSN | 0951-7375 ; 1355-834X |
DOI | 10.1097/00001432-199710000-00008 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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