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  1. AU=Oltean Mihai
  2. AU="Relph, Katharine A"
  3. AU=Li Jifen AU=Li Jifen
  4. AU="Diamant, Eran"
  5. AU="Kyoung, Henry" AU="Kyoung, Henry"
  6. AU=al-Gazali L I
  7. AU="Maillet, Jean-Michel"
  8. AU="Enlong Liu"
  9. AU="Afria, Dikshant"
  10. AU="Duggal, M. S."
  11. AU="Narcisa G. Pricope"
  12. AU="Kunisada, Toshiyuki"
  13. AU="Barvkar, Vitthal"

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Treffer 1 - 10 von insgesamt 131

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  1. Artikel ; Online: Transplant Immunobiology: Many Answers Raising Even More Questions.

    Oltean, Mihai

    International journal of molecular sciences

    2023  Band 24, Heft 16

    Abstract: Immunologic complications following organ, cell, or tissue transplantation still raise significant challenges related to their diagnosis and treatment [ ... ]. ...

    Abstract Immunologic complications following organ, cell, or tissue transplantation still raise significant challenges related to their diagnosis and treatment [...].
    Mesh-Begriff(e) Transplants
    Sprache Englisch
    Erscheinungsdatum 2023-08-11
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241612674
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Ischemic Preconditioning in Liver Transplantation: Lost in Translation?

    Oltean, Mihai

    Journal of investigative surgery : the official journal of the Academy of Surgical Research

    2021  Band 35, Heft 4, Seite(n) 910–911

    Mesh-Begriff(e) Humans ; Ischemic Preconditioning ; Liver Transplantation/adverse effects ; Reperfusion Injury/etiology ; Reperfusion Injury/prevention & control
    Sprache Englisch
    Erscheinungsdatum 2021-07-02
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 639444-9
    ISSN 1521-0553 ; 0894-1939
    ISSN (online) 1521-0553
    ISSN 0894-1939
    DOI 10.1080/08941939.2021.1943574
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 2364: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Artikel ; Online: Intestinal transplantation: an overview of the recent experimental studies.

    Oltean, Mihai

    Current opinion in organ transplantation

    2021  Band 26, Heft 2, Seite(n) 240–244

    Abstract: Purpose of review: Experimental intestinal transplantation (ITx ) has generated invaluable knowledge that has ultimately benefited the clinical activity. Herein, we appraise the recent publications pertaining to experimental ITx and highlight the main ... ...

    Abstract Purpose of review: Experimental intestinal transplantation (ITx ) has generated invaluable knowledge that has ultimately benefited the clinical activity. Herein, we appraise the recent publications pertaining to experimental ITx and highlight the main current research topics.
    Recent findings: During the recent years, ischemia-reperfusion injury (IRI) and Graft-versus-host disease (GVHD) have gradually replaced acute rejection as the main research topic. New additives to established preservation solutions and relatively novel approaches such as luminal interventions during cold storage may prolong the storage time and alleviate IRI. High donor age does not seem to worsen preservation injury. The ischemic susceptibility seems to differ between species, which may impact the translatability of the experimental findings. A new experimental model of modified multivisceral transplantation including the donor spleen may offer a new tool with which to study GVHD, besides the classical Lewis-Brown Norway rat combination. Flushing the graft with fludarabine may mitigate GVHD in rats. T-cell activation inhibitor-mitochondrial was downregulated in the peripheral blood leukocytes before other signs of acute and severe chronic rejection could be observed.
    Summary: Experimental research in ITx has largely shifted focus from acute rejection to IRI and GVHD. Several lines of research have matured toward clinical translation, yet no breakthrough is imminent.
    Mesh-Begriff(e) Animals ; Graft vs Host Disease/prevention & control ; Humans ; Intestines ; Rats ; Rats, Inbred Lew ; Reperfusion Injury/etiology ; Reperfusion Injury/prevention & control ; Transplantation, Homologous
    Sprache Englisch
    Erscheinungsdatum 2021-01-04
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1390429-2
    ISSN 1531-7013 ; 1087-2418
    ISSN (online) 1531-7013
    ISSN 1087-2418
    DOI 10.1097/MOT.0000000000000845
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5609: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

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  4. Artikel ; Online: B-Cell Dysfunction in Septic Shock: Still Flying Below the Radar.

    Oltean, Mihai

    Critical care medicine

    2020  Band 48, Heft 6, Seite(n) 923–924

    Mesh-Begriff(e) B-Lymphocytes ; Humans ; Radar ; Shock, Septic
    Sprache Englisch
    Erscheinungsdatum 2020-05-20
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004325
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1261: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: Intestinal Transplant Immunology and Intestinal Graft Rejection: From Basic Mechanisms to Potential Biomarkers.

    Rumbo, Martin / Oltean, Mihai

    International journal of molecular sciences

    2023  Band 24, Heft 5

    Abstract: Intestinal transplantation (ITx) remains a lifesaving option for patients suffering from irreversible intestinal failure and complications from total parenteral nutrition. Since its inception, it became obvious that intestinal grafts are highly ... ...

    Abstract Intestinal transplantation (ITx) remains a lifesaving option for patients suffering from irreversible intestinal failure and complications from total parenteral nutrition. Since its inception, it became obvious that intestinal grafts are highly immunogenic, due to their high lymphoid load, the abundance in epithelial cells and constant exposure to external antigens and microbiota. This combination of factors and several redundant effector pathways makes ITx immunobiology unique. To this complex immunologic situation, which leads to the highest rate of rejection among solid organs (>40%), there is added the lack of reliable non-invasive biomarkers, which would allow for frequent, convenient and reliable rejection surveillance. Numerous assays, of which several were previously used in inflammatory bowel disease, have been tested after ITx, but none have shown sufficient sensibility and/or specificity to be used alone for diagnosing acute rejection. Herein, we review and integrate the mechanistic aspects of graft rejection with the current knowledge of ITx immunobiology and summarize the quest for a noninvasive biomarker of rejection.
    Mesh-Begriff(e) Humans ; Graft Rejection/etiology ; Intestines ; Liver Transplantation ; Inflammatory Bowel Diseases ; Parenteral Nutrition, Total
    Sprache Englisch
    Erscheinungsdatum 2023-02-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24054541
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Buch ; Online: Improving the Search by Encoding Multiple Solutions in a Chromosome

    Oltean, Mihai

    2021  

    Abstract: We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the chromosome ... ...

    Abstract We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the chromosome decoding process must have the same complexity as in the case of a single solution in a chromosome. Three Genetic Programming techniques are analyzed for this purpose: Multi Expression Programming, Linear Genetic Programming, and Infix Form Genetic Programming. Numerical experiments show that encoding multiple solutions in a chromosome greatly improves the search process.

    Comment: 7 figures
    Schlagwörter Computer Science - Neural and Evolutionary Computing ; Computer Science - Artificial Intelligence
    Erscheinungsdatum 2021-10-13
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  7. Buch ; Online: Evolving Evolutionary Algorithms with Patterns

    Oltean, Mihai

    2021  

    Abstract: A new model for evolving Evolutionary Algorithms (EAs) is proposed in this paper. The model is based on the Multi Expression Programming (MEP) technique. Each MEP chromosome encodes an evolutionary pattern that is repeatedly used for generating the ... ...

    Abstract A new model for evolving Evolutionary Algorithms (EAs) is proposed in this paper. The model is based on the Multi Expression Programming (MEP) technique. Each MEP chromosome encodes an evolutionary pattern that is repeatedly used for generating the individuals of a new generation. The evolved pattern is embedded into a standard evolutionary scheme that is used for solving a particular problem. Several evolutionary algorithms for function optimization are evolved by using the considered model. The evolved evolutionary algorithms are compared with a human-designed Genetic Algorithm. Numerical experiments show that the evolved evolutionary algorithms can compete with standard approaches for several well-known benchmarking problems.

    Comment: arXiv admin note: substantial text overlap with arXiv:2109.13110
    Schlagwörter Computer Science - Neural and Evolutionary Computing ; Computer Science - Artificial Intelligence
    Erscheinungsdatum 2021-10-10
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  8. Buch ; Online: Solving even-parity problems using traceless genetic programming

    Oltean, Mihai

    2021  

    Abstract: A genetic programming (GP) variant called traceless genetic programming (TGP) is proposed in this paper. TGP is a hybrid method combining a technique for building individuals and a technique for representing individuals. The main difference between TGP ... ...

    Abstract A genetic programming (GP) variant called traceless genetic programming (TGP) is proposed in this paper. TGP is a hybrid method combining a technique for building individuals and a technique for representing individuals. The main difference between TGP and other GP techniques is that TGP does not explicitly store the evolved computer programs. Two genetic operators are used in conjunction with TGP: crossover and insertion. TGP is applied for evolving digital circuits for the even-parity problem. Numerical experiments show that TGP outperforms standard GP with several orders of magnitude.

    Comment: 7 Figures, 3 Tables
    Schlagwörter Computer Science - Neural and Evolutionary Computing ; Computer Science - Artificial Intelligence
    Erscheinungsdatum 2021-10-04
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Buch ; Online: Evolving winning strategies for Nim-like games

    Oltean, Mihai

    2021  

    Abstract: An evolutionary approach for computing the winning strategy for Nim-like games is proposed in this paper. The winning strategy is computed by using the Multi Expression Programming (MEP) technique - a fast and efficient variant of the Genetic Programming ...

    Abstract An evolutionary approach for computing the winning strategy for Nim-like games is proposed in this paper. The winning strategy is computed by using the Multi Expression Programming (MEP) technique - a fast and efficient variant of the Genetic Programming (GP). Each play strategy is represented by a mathematical expression that contains mathematical operators (such as +, -, *, mod, div, and , or, xor, not) and operands (encoding the current game state). Several numerical experiments for computing the winning strategy for the Nim game are performed. The computational effort needed for evolving a winning strategy is reported. The results show that the proposed evolutionary approach is very suitable for computing the winning strategy for Nim-like games.

    Comment: 9 pages
    Schlagwörter Computer Science - Neural and Evolutionary Computing ; Computer Science - Artificial Intelligence
    Erscheinungsdatum 2021-08-21
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  10. Buch ; Online: Evolving Evolutionary Algorithms using Linear Genetic Programming

    Oltean, Mihai

    2021  

    Abstract: A new model for evolving Evolutionary Algorithms is proposed in this paper. The model is based on the Linear Genetic Programming (LGP) technique. Every LGP chromosome encodes an EA which is used for solving a particular problem. Several Evolutionary ... ...

    Abstract A new model for evolving Evolutionary Algorithms is proposed in this paper. The model is based on the Linear Genetic Programming (LGP) technique. Every LGP chromosome encodes an EA which is used for solving a particular problem. Several Evolutionary Algorithms for function optimization, the Traveling Salesman Problem, and the Quadratic Assignment Problem are evolved by using the considered model. Numerical experiments show that the evolved Evolutionary Algorithms perform similarly and sometimes even better than standard approaches for several well-known benchmarking problems.

    Comment: 23 pages, 3 figures
    Schlagwörter Computer Science - Neural and Evolutionary Computing ; Computer Science - Artificial Intelligence
    Erscheinungsdatum 2021-08-21
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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