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  1. Article ; Online: The Growing Challenge of Diabetes Management in an Aging Society.

    Lee, Seung-Hwan

    Diabetes & metabolism journal

    2023  Volume 47, Issue 5, Page(s) 630–631

    MeSH term(s) Humans ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/therapy ; Aging
    Language English
    Publishing date 2023-09-26
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2602402-0
    ISSN 2233-6087 ; 2233-6087
    ISSN (online) 2233-6087
    ISSN 2233-6087
    DOI 10.4093/dmj.2023.0279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cardiovascular Risk Reduction in Type 2 Diabetes: Further Insights into the Power of Weight Loss and Exercise.

    Lee, Seung-Hwan

    Endocrinology and metabolism (Seoul, Korea)

    2023  Volume 38, Issue 3, Page(s) 302–304

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2 ; Risk Factors ; Cardiovascular Diseases/prevention & control ; Weight Loss ; Heart Disease Risk Factors
    Language English
    Publishing date 2023-06-28
    Publishing country Korea (South)
    Document type Editorial ; Comment
    ZDB-ID 2802452-7
    ISSN 2093-5978 ; 2093-5978
    ISSN (online) 2093-5978
    ISSN 2093-5978
    DOI 10.3803/EnM.2023.1751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply: Distal Radial Artery Access.

    Lee, Jun-Won / Lee, Seung-Hwan

    JACC. Cardiovascular interventions

    2024  Volume 17, Issue 8, Page(s) 1067–1068

    MeSH term(s) Radial Artery/diagnostic imaging ; Humans ; Catheterization, Peripheral/adverse effects ; Treatment Outcome ; Risk Factors ; Punctures ; Percutaneous Coronary Intervention/instrumentation
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Letter
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2024.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Tiny CRISPR molecular switch tool opens a new world.

    Oh, Yeounsun / Lee, Seung Hwan

    Molecular therapy : the journal of the American Society of Gene Therapy

    2024  Volume 32, Issue 4, Page(s) 870–872

    MeSH term(s) Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; CRISPR-Cas Systems ; Gene Editing
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2010592-7
    ISSN 1525-0024 ; 1525-0016
    ISSN (online) 1525-0024
    ISSN 1525-0016
    DOI 10.1016/j.ymthe.2024.03.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5640: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Online: Flexible and Stretchable Electronics

    Lee, Daeho / Ko, Seung Hwan / Wu, Zhigang

    2017  

    Abstract: Flexible and stretchable electronics are receiving tremendous attention as future electronics due to their flexibility and light weight, especially as applications in wearable electronics. Flexible electronics are usually fabricated on heat sensitive ... ...

    Abstract Flexible and stretchable electronics are receiving tremendous attention as future electronics due to their flexibility and light weight, especially as applications in wearable electronics. Flexible electronics are usually fabricated on heat sensitive flexible substrates such as plastic, fabric or even paper, while stretchable electronics are usually fabricated from an elastomeric substrate to survive large deformation in their practical application. Therefore, successful fabrication of flexible electronics needs low temperature processable novel materials and a particular processing development because traditional materials and processes are not compatible with flexible/stretchable electronics. Huge technical challenges and opportunities surround these dramatic changes from the perspective of new material design and processing, new fabrication techniques, large deformation mechanics, new application development and so on. Here, we invited talented researchers to join us in this new vital field that holds the potential to reshape our future life, by contributing their words of wisdom from their particular perspective
    Keywords Technology (General)
    Size 1 electronic resource (VIII, 172 p.)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020094607
    ISBN 9783038424369 ; 9783038424376 ; 3038424366 ; 3038424374
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article: Effects of Oxidized Metal Powders on Pore Defects in Powder-Fed Direct Energy Deposition.

    Son, Jong-Youn / Lee, Ki-Yong / Lee, Seung Hwan / Choi, Chang-Hwan

    Micromachines

    2024  Volume 15, Issue 2

    Abstract: Laser-based additive manufacturing processes, particularly direct energy deposition (DED), have gained prominence for fabricating complex, functionally graded, or customized parts. DED employs a high-powered heat source to melt metallic powder or wire, ... ...

    Abstract Laser-based additive manufacturing processes, particularly direct energy deposition (DED), have gained prominence for fabricating complex, functionally graded, or customized parts. DED employs a high-powered heat source to melt metallic powder or wire, enabling precise control of grain structures and the production of high-strength objects. However, common defects, such as a lack of fusion and pores between layers or beads, can compromise the mechanical properties of the printed components. This study focuses on investigating the recurrent causes of pore defects in the powder-fed DED process, with a specific emphasis on the influence of oxidized metal powders. This research explores the impact of intentionally oxidizing metal powders of hot work tool steel H13 by exposing them to regulated humidity and temperature conditions. Scanning electron microscopy images and energy-dispersive X-ray spectroscopy results demonstrate the clumping of powders and the deposition of iron oxides in the oxidized powders at elevated temperatures (70 °C for 72 h). Multi-layered depositions of the oxidized H13 powders on STD61 substrate do not show significant differences in cross sections among specimens, suggesting that oxidation does not visibly form large pores. However, fine pores, detected through CT scanning, are observed in depositions of oxidized powders at higher temperatures. These fine pores, typically less than 250 µm in diameter, are irregularly distributed throughout the deposition, indicating a potential degradation in mechanical properties. The findings highlight the need for careful consideration of oxidation effects in optimizing process parameters for enhanced additive manufacturing quality.
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15020243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Expanding the therapeutic landscape

    Jeongmin Lee / Seung-Hwan Lee

    The Korean Journal of Internal Medicine, Vol 38, Iss 6, Pp 797-

    ezetimibe as non-statin therapy for dyslipidemia

    2023  Volume 809

    Abstract: Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve ... ...

    Abstract Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve optimal LDL-C goals with statin monotherapy. Ezetimibe, a cholesterol absorption inhibitor, offers a potential non-statin therapy to optimize LDL-C management. Key clinical trials, such as IMPROVE-IT and RACING, have demonstrated that the addition of ezetimibe to statin therapy leads to further decreases in LDL-C or significant decreases in major adverse cardiovascular events (MACEs), particularly in patients with high ASCVD risk. Subsequent meta-analyses and clinical trials have further supported the beneficial effect of ezetimibe, suggesting additive decreases in LDL-C and MACEs, as well as pleiotropic effects. This review provides a comprehensive analysis of the clinical implications of ezetimibe for managing dyslipidemia; it also evaluates the available evidence that supports the role of ezetimibe as an adjunct non-statin therapy for long-term use. However, the long-term pleiotropic effects of ezetimibe remain controversial because of limited clinical data. Therefore, additional research is needed to clarify its potential benefits beyond LDL-C reduction. Nonetheless, an understanding of the role of ezetimibe in dyslipidemia management will help clinicians to develop effective treatment strategies.
    Keywords atherosclerosis ; cardiovascular disease ; dyslipidemias ; ezetimibe ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher The Korean Association of Internal Medicine
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Article ; Online: A rare case of pelvic concurrent schwannoma(neurilemmoma) and neurofibroma.

    Lee, Seung Hwan / Lee, Sung Jong / Lee, Chul Seung

    Asian journal of surgery

    2022  Volume 45, Issue 4, Page(s) 1084–1085

    MeSH term(s) Humans ; Neurilemmoma/complications ; Neurilemmoma/diagnostic imaging ; Neurilemmoma/surgery ; Neurofibroma/diagnostic imaging ; Neurofibroma/surgery ; Pelvis
    Language English
    Publishing date 2022-02-17
    Publishing country China
    Document type Case Reports ; Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2022.01.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Innovative stacked liquid crystal panel for automotive display: driver-oriented privacy and passenger accessibility.

    Lee, Jae-Hwan / Oh, Seung-Won

    Optics letters

    2023  Volume 48, Issue 22, Page(s) 6023–6026

    Abstract: We propose a switchable privacy display with liquid crystals for co-driver displays (CDDs) in vehicles. The display minimizes driver distraction while allowing the co-driver to enjoy infotainment content. By combining electrically controllable ... ...

    Abstract We propose a switchable privacy display with liquid crystals for co-driver displays (CDDs) in vehicles. The display minimizes driver distraction while allowing the co-driver to enjoy infotainment content. By combining electrically controllable birefringence (ECB) and hybrid-aligned nematic (HAN) cells, we control the viewing angle of the display. Our device achieves an operating angle of 30°, effectively blocking the driver's view while providing a wide viewing angle for the co-driver. It maintains excellent transmittance properties in privacy and public modes, with symmetric luminance characteristics. The versatility of the proposed display extends to various technologies like LCDs, OLEDs, and micro-LEDs. This switchable privacy display has the potential to enhance driver safety and infotainment experiences in vehicles.
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.507083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Expanding the therapeutic landscape: ezetimibe as non-statin therapy for dyslipidemia.

    Lee, Jeongmin / Lee, Seung-Hwan

    The Korean journal of internal medicine

    2023  Volume 38, Issue 6, Page(s) 797–809

    Abstract: Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve ... ...

    Abstract Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve optimal LDL-C goals with statin monotherapy. Ezetimibe, a cholesterol absorption inhibitor, offers a potential non-statin therapy to optimize LDL-C management. Key clinical trials, such as IMPROVE-IT and RACING, have demonstrated that the addition of ezetimibe to statin therapy leads to further decreases in LDL-C or significant decreases in major adverse cardiovascular events (MACEs), particularly in patients with high ASCVD risk. Subsequent meta-analyses and clinical trials have further supported the beneficial effect of ezetimibe, suggesting additive decreases in LDL-C and MACEs, as well as pleiotropic effects. This review provides a comprehensive analysis of the clinical implications of ezetimibe for managing dyslipidemia; it also evaluates the available evidence that supports the role of ezetimibe as an adjunct non-statin therapy for long-term use. However, the long-term pleiotropic effects of ezetimibe remain controversial because of limited clinical data. Therefore, additional research is needed to clarify its potential benefits beyond LDL-C reduction. Nonetheless, an understanding of the role of ezetimibe in dyslipidemia management will help clinicians to develop effective treatment strategies.
    MeSH term(s) Humans ; Ezetimibe/adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Cholesterol, LDL ; Anticholesteremic Agents/adverse effects ; Dyslipidemias/diagnosis ; Dyslipidemias/drug therapy ; Drug Therapy, Combination ; Treatment Outcome
    Chemical Substances Ezetimibe (EOR26LQQ24) ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Cholesterol, LDL ; Anticholesteremic Agents
    Language English
    Publishing date 2023-10-20
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 639023-7
    ISSN 2005-6648 ; 1226-3303
    ISSN (online) 2005-6648
    ISSN 1226-3303
    DOI 10.3904/kjim.2023.243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3028: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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