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  1. Article: Temporally probing the thermal phonon and charge transfer induced out-of-plane acoustical displacement of monolayer and bi-layer MoS

    Wang, Peng-Jui / Chang, Che-Jia / Lin, Shih-Yen / Sheu, Jinn-Kong / Sun, Chi-Kuang

    Photoacoustics

    2023  Volume 30, Page(s) 100477

    Abstract: Acoustical behavior of semiconducting transition metal dichalcogenides determines the heat transfer pathway, and thus plays a crucial role in the electronics and optoelectronics design. In this research, van der Waals heterojunctions (vdWHs) consisting ... ...

    Abstract Acoustical behavior of semiconducting transition metal dichalcogenides determines the heat transfer pathway, and thus plays a crucial role in the electronics and optoelectronics design. In this research, van der Waals heterojunctions (vdWHs) consisting of transferred monolayer and bi-layer MoS
    Language English
    Publishing date 2023-03-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2716706-9
    ISSN 2213-5979
    ISSN 2213-5979
    DOI 10.1016/j.pacs.2023.100477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Revealing the interlayer van der Waals coupling of bi-layer and tri-layer MoS

    Wang, Peng-Jui / Tsai, Po-Cheng / Yang, Zih-Sian / Lin, Shih-Yen / Sun, Chi-Kuang

    Photoacoustics

    2022  Volume 28, Page(s) 100412

    Abstract: In this research, we applied THz coherent phonon spectroscopy to optically probe the vibrational modes of the epitaxially-grown bi-layer and tri-layer ... ...

    Abstract In this research, we applied THz coherent phonon spectroscopy to optically probe the vibrational modes of the epitaxially-grown bi-layer and tri-layer MoS
    Language English
    Publishing date 2022-10-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2716706-9
    ISSN 2213-5979
    ISSN 2213-5979
    DOI 10.1016/j.pacs.2022.100412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Exploring the effects of sudden institutional coercive pressure on digital transformation in colleges from teachers' perspective.

    Lu, Hsi-Peng / Wang, Jui-Chi

    Education and information technologies

    2023  , Page(s) 1–25

    Abstract: While past technology acceptance studies focus on organization readiness, little is known about the acceptance behavior under sudden institutional coercive pressure. Against COVID-19 and distance teaching, this study explores the relationship between ... ...

    Abstract While past technology acceptance studies focus on organization readiness, little is known about the acceptance behavior under sudden institutional coercive pressure. Against COVID-19 and distance teaching, this study explores the relationship between digital transformation readiness, adoption intention, digital transformation success, and sudden institutional coercive pressure based on the readiness research model and institutional theory. Surveying 233 college teachers who participated in distance teaching under COVID-19 in Taiwan for model and hypothesis validation using the partial least square structural equation modeling (PLS-SEM) approach. This result shows that (1) Teacher, social/public, and content readiness are crucial to distance teaching. Individuals, organizational resources, and external stakeholders influence distance teaching success and adoption; and (2) Sudden institutional coercive pressure has a negative moderated effect on teachers' readiness and adoption intention. When teachers are unprepared to implement distance teaching, this unanticipated epidemic and sudden institutional coercive pressure will accelerate and enhance their intention. The study provides government, educational policymakers, and teachers with a better understanding of distance teaching during the COVID-19 pandemic.
    Language English
    Publishing date 2023-05-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2001930-0
    ISSN 1573-7608 ; 1360-2357
    ISSN (online) 1573-7608
    ISSN 1360-2357
    DOI 10.1007/s10639-023-11781-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Microwave resonant absorption of SARS-CoV-2 viruses.

    Wang, Peng-Jui / Pang, Yu-Hao / Huang, Sheng-Yu / Fang, Jun-Tung / Chang, Sui-Yuan / Shih, Shin-Ru / Huang, Tian-Wei / Chen, Yi-Jan / Sun, Chi-Kuang

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 12596

    Abstract: Low power microwave can effectively deactivate influenza type A virus through the nonthermal structure-resonant energy transfer effect, at a frequency matching the confined-acoustic dipolar mode frequency of the virus. Currently, aerosol is considered ... ...

    Abstract Low power microwave can effectively deactivate influenza type A virus through the nonthermal structure-resonant energy transfer effect, at a frequency matching the confined-acoustic dipolar mode frequency of the virus. Currently, aerosol is considered the major route for SARS-CoV-2 transmission. For the potential microwave-based sterilization, the microwave-resonant frequency of SARS-CoV-2 must be unraveled. Here we report a microwave absorption spectroscopy study of the SARS-CoV-2 and HCoV-229E viruses through devising a coplanar-waveguide-based sensor. Noticeable microwave absorption can be observed, while we identified the resonant frequencies of the 1st and 2nd dipolar modes of SARS-CoV-2 virus as 4 and 7.5 GHz respectively. We further found that the resonant frequencies are invariant to the virus titer, and we also studied the microwave absorption of HCoV-229E in weak acidity medium to simulate the common pH value in fluid secretion. Our results suggest the possible radiation frequency for the recently proposed microwave sterilization devices to inactivate SARS-CoV-2 virus through a nonthermal mechanism so as to control the disease transmission in the post-pandemic era.
    MeSH term(s) COVID-19 ; Coronavirus 229E, Human ; Humans ; Microwaves ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2022-07-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-16845-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Orally Ingested Self-Powered Stimulators for Targeted Gut-Brain Axis Electrostimulation to Treat Obesity and Metabolic Disorders.

    Mac, Cam-Hoa / Tai, Hsien-Meng / Huang, Sheng-Min / Peng, Hsu-Hsia / Sharma, Amit Kumar / Nguyen, Giang Le Thi / Chang, Pei-Ju / Wang, Jui-To / Chang, Yen / Lin, Yu-Jung / Sung, Hsing-Wen

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2310351

    Abstract: Obesity is a significant health concern that often leads to metabolic dysfunction and chronic diseases. This study introduces a novel approach to combat obesity using orally ingested self-powered electrostimulators. These electrostimulators consist of ... ...

    Abstract Obesity is a significant health concern that often leads to metabolic dysfunction and chronic diseases. This study introduces a novel approach to combat obesity using orally ingested self-powered electrostimulators. These electrostimulators consist of piezoelectric BaTiO
    Language English
    Publishing date 2024-04-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202310351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Adjuvant Sorafenib for Postoperative Patients with Hepatocellular Carcinoma and Macrovascular Invasion.

    Chang, Che-Jui / Hsu, Wei-Fan / Jeng, Long-Bin / Lai, Hsueh-Chou / Hsu, Shih-Chao / Chen, Te-Hung / Wang, Hung-Wei / Peng, Cheng-Yuan

    Current oncology (Toronto, Ont.)

    2023  Volume 30, Issue 12, Page(s) 10134–10141

    Abstract: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality in Taiwan. Some patients with HCC are diagnosed with macrovascular invasion (MVI), which is associated with a poorer prognosis. In Taiwan, sorafenib is the first-line therapy ... ...

    Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality in Taiwan. Some patients with HCC are diagnosed with macrovascular invasion (MVI), which is associated with a poorer prognosis. In Taiwan, sorafenib is the first-line therapy for patients with advanced HCC. However, the efficacy of adjuvant sorafenib therapy remains unclear for the subset of patients with HCC and MVI who are eligible for surgery. Therefore, we investigated the potential benefit of adjuvant sorafenib therapy for patients with HCC and MVI after surgery. Our study showed that the lack of improved PFS or OS of adjuvant sorafenib challenged the therapeutic benefit of postoperative sorafenib. Alcohol consumption and an α-fetoprotein level of ≥400 ng/mL were independent predictors of overall survival (OS); however, adjuvant sorafenib therapy was not a predictor of progression-free survival (PFS) or OS. In conclusion, our study indicated that adjuvant sorafenib therapy did not provide PFS or OS benefits in patients with HCC and MVI.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/surgery ; Sorafenib/therapeutic use ; Liver Neoplasms/drug therapy ; Liver Neoplasms/surgery ; Antineoplastic Agents/therapeutic use ; Combined Modality Therapy
    Chemical Substances Sorafenib (9ZOQ3TZI87) ; Antineoplastic Agents
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol30120737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: New classification for bone type at dental implant sites: a dental computed tomography study.

    Wang, Shiuan-Hui / Hsu, Jui-Ting / Fuh, Lih-Jyh / Peng, Shin-Lei / Huang, Heng-Li / Tsai, Ming-Tzu

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 324

    Abstract: Objective: This study proposed a new classification method of bone quantity and quality at the dental implant site using cone-beam computed tomography (CBCT) image analysis, classifying cortical and cancellous bones separately and using CBCT for ... ...

    Abstract Objective: This study proposed a new classification method of bone quantity and quality at the dental implant site using cone-beam computed tomography (CBCT) image analysis, classifying cortical and cancellous bones separately and using CBCT for quantitative analysis.
    Methods: Preoperative CBCT images were obtained from 128 implant patients (315 sites). First, measure the crestal cortical bone thickness (in mm) and the cancellous bone density [in grayscale values (GV) and bone mineral density (g/cm
    Results: The results of the nine bone type proportions based on the new jawbone classification were as follows: A1 (8.57%,27/315), A2 (13.02%), A3 (4.13%), B1 (17.78%), B2 (20.63%), B3 (8.57%) C1 (4.44%), C2 (14.29%), and C3 (8.57%).
    Conclusions: The proposed classification can complement the parts overlooked in previous bone classification methods (bone types A3 and C1).
    Trial registration: The retrospective registration of this study was approved by the Institutional Review Board of China Medical University Hospital, No. CMUH 108-REC2-181.
    MeSH term(s) Humans ; Dental Implants ; Retrospective Studies ; Tomography, X-Ray Computed ; Jaw ; Cone-Beam Computed Tomography ; Bone Density
    Chemical Substances Dental Implants
    Language English
    Publishing date 2023-05-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03039-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optimal Heart Rate Control Improves Long-Term Prognosis of Decompensated Heart Failure with Reduced Ejection Fraction.

    Tsai, Ming-Lung / Lin, Shu-I / Kao, Yu-Cheng / Lin, Hsuan-Ching / Lin, Ming-Shyan / Peng, Jian-Rong / Wang, Chao-Yung / Wu, Victor Chien-Chia / Cheng, Chi-Wen / Lee, Ying-Hsiang / Hung, Ming-Jui / Chen, Tien-Hsing

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 2

    Abstract: Background and Objectives: ...

    Abstract Background and Objectives:
    MeSH term(s) Humans ; Stroke Volume/physiology ; Ventricular Function, Left/physiology ; Heart Failure ; Heart Rate ; Ventricular Dysfunction, Left ; Prognosis ; Hospitalization
    Language English
    Publishing date 2023-02-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59020348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Role of the stress-responsive two-component system CpxAR in regulating fimbriae expression in Klebsiella pneumoniae CG43.

    Kuo, Chih-Hao / Lin, Wei-Feng / Liu, Chia-Jui / Wang, Zhe-Chong / Liu, Ting-Yi / Peng, Hwei-Ling

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2023  Volume 56, Issue 3, Page(s) 464–476

    Abstract: Background: CpxAR is a two-component system that allows bacteria to reorganize envelope structures in response to extracellular stimuli. CpxAR negatively affects type 1 fimbriae expression in Klebsiella pneumoniae CG43, a hypervirulent strain. The ... ...

    Abstract Background: CpxAR is a two-component system that allows bacteria to reorganize envelope structures in response to extracellular stimuli. CpxAR negatively affects type 1 fimbriae expression in Klebsiella pneumoniae CG43, a hypervirulent strain. The involvement of CpxAR in the regulation of type 3 fimbriae expression was investigated.
    Methods: cpxAR, cpxA, and cpxR gene-specific deletion mutants were generated. The deletion effects on the expression of type 1 and type 3 fimbriae were analyzed via measuring the promoter activity, mannose sensitive yeast agglutination activity, biofilm formation, and the production of the major pilins FimA and MrkA respectively. RNA sequencing analysis of CG43S3, ΔcpxAR, ΔcpxR and Δfur was employed to study the regulatory mechanism influencing the expression of type 3 fimbriae.
    Results: Deletion of cpxAR increased type 1 and type 3 fimbrial expression. Comparative transcriptomic analysis showed that the expression of oxidative stress-responsive enzymes, type 1 and type 3 fimbriae, and iron acquisition and homeostasis control systems were differentially affected by cpxAR or cpxR deletion. Subsequent analysis revealed that the small RNA RyhB negatively affects the expression of type 3 fimbriae, while CpxAR positively controls ryhB expression. Finally, the site-directed mutation of the predicted interacting sequences of RyhB with the mRNA of MrkA attenuated the RyhB repression of type 3 fimbriae.
    Conclusion: CpxAR negatively regulates the expression of type 3 fimbriae by modulating cellular iron levels thereafter activating the expression of RyhB. The activated RyhB represses the expression of type 3 fimbriae by base-pairing binding to the 5'region of mrkA mRNA.
    MeSH term(s) Humans ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Klebsiella pneumoniae ; Fimbriae, Bacterial/genetics ; Fimbriae, Bacterial/metabolism ; Fimbriae Proteins/genetics ; Fimbriae Proteins/metabolism ; RNA, Messenger ; Iron/metabolism
    Chemical Substances Bacterial Proteins ; Fimbriae Proteins (147680-16-8) ; RNA, Messenger ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-02-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2023.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Probing Anti-Leukemic Metabolites from Marine-Derived

    Chen, You-Ying / Chen, Lo-Yun / Chen, Po-Jen / El-Shazly, Mohamed / Peng, Bo-Rong / Chen, Yu-Cheng / Su, Chun-Han / Su, Jui-Hsin / Sung, Ping-Jyun / Yen, Pei-Tzu / Wang, Lung-Shuo / Lai, Kuei-Hung

    Metabolites

    2022  Volume 12, Issue 4

    Abstract: The unmet need for specific anti-leukemic agents for the treatment of acute lymphoblastic leukemia led us to screen a variety of marine-derived bacteria. The fermentation broth extract ... ...

    Abstract The unmet need for specific anti-leukemic agents for the treatment of acute lymphoblastic leukemia led us to screen a variety of marine-derived bacteria. The fermentation broth extract of
    Language English
    Publishing date 2022-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo12040320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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