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  1. Article ; Online: Rationing of Medical Supplies, Including Ventilators, for Patients With Kidney Disease.

    Jain, Gaurav

    Mayo Clinic proceedings

    2020  Volume 95, Issue 7, Page(s) 1550–1551

    MeSH term(s) COVID-19 ; Health Care Rationing/ethics ; Humans ; Kidney Failure, Chronic/therapy ; Renal Dialysis/methods ; SARS-CoV-2 ; Ventilators, Mechanical/supply & distribution
    Keywords covid19
    Language English
    Publishing date 2020-04-30
    Publishing country England
    Document type Letter
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2020.04.029
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    Ua VI Zs.183: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Experience with the largest custom-made 48 mm fenestrated atrial septal occluder device and its 4-year follow-up.

    Sivakumar, Kothandam / Jain, Gaurav

    Annals of pediatric cardiology

    2023  Volume 16, Issue 1, Page(s) 52–55

    Abstract: Atrial septal defects (ASDs) measuring <38 mm are referred for transcatheter closure. Availability of larger devices up to 46 mm extended the inclusion criteria. An elderly hypertensive male with a 44 mm secundum ASD and coexistent sick sinus syndrome ... ...

    Abstract Atrial septal defects (ASDs) measuring <38 mm are referred for transcatheter closure. Availability of larger devices up to 46 mm extended the inclusion criteria. An elderly hypertensive male with a 44 mm secundum ASD and coexistent sick sinus syndrome and atrioventricular (AV) nodal block presented with syncope. Balloon interrogation unmasked restrictive left ventricular (LV) physiology. After AV synchronous pacing, balloon-assisted deployment of a custom fenestrated 48 mm Figulla septal occluder (Occlutech Inc., Schaffhausen, Switzerland) prevented a rise of LV end-diastolic pressures beyond 12 mmHg. Echocardiogram and computed tomography after 4 years confirmed a patent fenestration and favorable remodeling. This report of the clinical use of the largest ASD device demonstrated the feasibility of closure of extremely large defects despite a restrictive LV.
    Language English
    Publishing date 2023-04-04
    Publishing country India
    Document type Case Reports
    ZDB-ID 2430956-4
    ISSN 0974-5149 ; 0974-2069
    ISSN (online) 0974-5149
    ISSN 0974-2069
    DOI 10.4103/apc.apc_126_22
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  3. Article ; Online: Experience with the largest custom-made 48 mm fenestrated atrial septal occluder device and its 4-year follow-up

    Kothandam Sivakumar / Gaurav Jain

    Annals of Pediatric Cardiology, Vol 16, Iss 1, Pp 52-

    2023  Volume 55

    Abstract: Atrial septal defects (ASDs) measuring <38 mm are referred for transcatheter closure. Availability of larger devices up to 46 mm extended the inclusion criteria. An elderly hypertensive male with a 44 mm secundum ASD and coexistent sick sinus syndrome ... ...

    Abstract Atrial septal defects (ASDs) measuring <38 mm are referred for transcatheter closure. Availability of larger devices up to 46 mm extended the inclusion criteria. An elderly hypertensive male with a 44 mm secundum ASD and coexistent sick sinus syndrome and atrioventricular (AV) nodal block presented with syncope. Balloon interrogation unmasked restrictive left ventricular (LV) physiology. After AV synchronous pacing, balloon-assisted deployment of a custom fenestrated 48 mm Figulla septal occluder (Occlutech Inc., Schaffhausen, Switzerland) prevented a rise of LV end-diastolic pressures beyond 12 mmHg. Echocardiogram and computed tomography after 4 years confirmed a patent fenestration and favorable remodeling. This report of the clinical use of the largest ASD device demonstrated the feasibility of closure of extremely large defects despite a restrictive LV.
    Keywords fenestrated device ; largest atrial septal occluder device ; nitinol septal occluder ; restrictive left ventricular physiology ; Medicine ; R ; Pediatrics ; RJ1-570 ; Diseases of the circulatory (Cardiovascular) system ; RC666-701
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Is There a Role for Alcohol Septal Ablation in Young Patients with Medically Refractory Hypertrophic Obstructive Cardiomyopathy?

    Sivakumar, Kothandam / Jain, Gaurav

    Pediatric cardiology

    2023  Volume 45, Issue 3, Page(s) 648–659

    Abstract: Surgical myectomy is recommended for symptomatic hypertrophic obstructive cardiomyopathy (HOCM) after optimal pharmacological therapy. Percutaneous transluminal septal myocardial ablation (PTSMA) is reserved for high-risk adults. Symptomatic patients ... ...

    Abstract Surgical myectomy is recommended for symptomatic hypertrophic obstructive cardiomyopathy (HOCM) after optimal pharmacological therapy. Percutaneous transluminal septal myocardial ablation (PTSMA) is reserved for high-risk adults. Symptomatic patients below 25 years underwent either surgery or PTSMA after heart-team discussion and informed consent. Echocardiography assessed gradients in surgical group. PTSMA group underwent invasive transseptal hemodynamic assessment, selective coronary angiography and super-selective cannulation of septal perforators using microcatheters. Contrast echocardiography through the microcatheter identified the myocardial target for PTSMA. Hemodynamic and electrocardiographic monitoring guided alcohol injection. Both groups were continued on beta-blockers. Symptoms, echocardiographic gradients and Brain natriuretic peptide (NTproBNP) measurements were assessed on follow-up. Twelve patients aged 5-23 years (11-98 kg) formed the study group. Indications for PTSMA in 8 patients included abnormal mitral valve anatomy warranting replacement (n = 3), Jehovah's witness (n = 2), severe neurodevelopmental and growth retardation (n = 1) and refusal of surgery (n = 2). PTSMA targeted first perforator (n = 5), second perforator (n = 2) and anomalous septal artery from left main trunk (n = 1). Outflow gradient reduced from 92.5 ± 19.7 to 33.1 ± 13.5 mmHg. At a median follow-up of 38 months (range 3-120 weeks), the peak instantaneous echocardiographic gradient was 32 ± 16.5 mmHg. Gradient reduced in four surgical patients from 86.5 ± 16.3 mmHg to 42 ± 14.7 mm Hg. All patients were in NYHA class I/II on follow-up. The mean NTproBNP in PTSMA group reduced from 6084 ± 3628 pg/ml to 3081 ± 2019 pg/ml; it was 1396 and 1795 pg/ml in surgery. PTSMA may be considered in medically refractory high-risk young patients. It relieves symptoms and reduces gradient. Though surgery is preferred in young patients, PTSMA may have a role in selected patients.
    MeSH term(s) Adult ; Humans ; Cardiac Surgical Procedures ; Cardiomyopathy, Hypertrophic/diagnostic imaging ; Cardiomyopathy, Hypertrophic/surgery ; Heart ; Vascular Surgical Procedures ; Myocardium
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800857-7
    ISSN 1432-1971 ; 0172-0643
    ISSN (online) 1432-1971
    ISSN 0172-0643
    DOI 10.1007/s00246-023-03145-6
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    Zs.A 1528: Show issues Location:
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  7. Article: Preoperative Diffusion Tensor Imaging in Supratentorial Intra-Axial Brain Tumors: Its Role in Predicting Tumor Histology and Prognosis as well in Surgical Planning and Resection.

    Singh, Ajay / Jain, Gaurav / Sharma, Vinod / Singh, Shaveta

    Asian journal of neurosurgery

    2023  Volume 18, Issue 3, Page(s) 476–483

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2023-09-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2621446-5
    ISSN 2248-9614 ; 1793-5482
    ISSN (online) 2248-9614
    ISSN 1793-5482
    DOI 10.1055/s-0043-1772758
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  8. Article ; Online: Retrospective Evaluation of Moderate Sedation Visits That Used Oral Meperidine and Hydroxyzine With Oral or Intranasal Midazolam.

    Jain, Gaurav / Curran, Ronald / Jones, Robert S

    Journal of dentistry for children (Chicago, Ill.)

    2023  Volume 90, Issue 3, Page(s) 139–146

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Humans ; Child ; Midazolam/adverse effects ; Hydroxyzine/adverse effects ; Meperidine ; Hypnotics and Sedatives ; Conscious Sedation ; Retrospective Studies ; Cross-Sectional Studies ; Drug Combinations ; Anesthesia, Dental
    Chemical Substances Midazolam (R60L0SM5BC) ; Hydroxyzine (30S50YM8OG) ; Meperidine (9E338QE28F) ; Hypnotics and Sedatives ; Drug Combinations
    Language English
    Publishing date 2023-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390120-8
    ISSN 1935-5068 ; 1551-8949 ; 0022-0353
    ISSN (online) 1935-5068
    ISSN 1551-8949 ; 0022-0353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 304: Show issues Location:
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  9. Article ; Online: Management of Post-Cholecystectomy Biliary Complications: Surgeon's Perspective.

    Gupta, Vishal / Jain, Gaurav

    The American journal of gastroenterology

    2021  Volume 116, Issue 4, Page(s) 838

    MeSH term(s) Biliary Tract ; Cholecystectomy ; Humans ; Surgeons
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000000973
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    Ui V Zs.36: Show issues Location:
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  10. Article ; Online: Emerging Role of Gallium-68 DOTANOC PET/CT Guided Radiofrequency Ablation in the Treatment of Tumor-induced Osteomalacia.

    Sharma, Jyoti / Kasliwal, Rajeev / Jain, Tarun / Sharma, Gaurav Kant

    JCEM case reports

    2024  Volume 2, Issue 5, Page(s) luae044

    Abstract: Tumor-induced osteomalacia (TIO) is a rare acquired form of hypophosphatemia that can be cured when the tumor responsible is completely removed. These tumors can be small and located in anatomically challenging areas, rendering surgery both risky and ... ...

    Abstract Tumor-induced osteomalacia (TIO) is a rare acquired form of hypophosphatemia that can be cured when the tumor responsible is completely removed. These tumors can be small and located in anatomically challenging areas, rendering surgery both risky and extensive. Radiofrequency ablation (RFA) has been explored as an effective treatment option for such tumors. We present a case of a 35-year-old man exhibiting clinical and biochemical features consistent with TIO. The culprit lesion was not detectable on the whole-body computed tomography (CT) scan. Gallium (Ga-68) DOTANOC positron emission tomography (PET)/CT showed increased uptake in the left acetabulum and magnetic resonance imaging (MRI) confirmed the location of the tumor. Given the risky anatomical location, we opted for less-invasive RFA. Following an unsuccessful attempt at CT-guided RFA of the lesion, we used real-time Ga-68 DOTANOC PET/CT guidance for precise imaging during the ablation procedure. Our patient achieved complete remission both clinically and biochemically after RFA. This response was also evident by the absence of tracer uptake in follow-up imaging. In conclusion, DOTANOC PET/CT-guided RFA can serve as a safe and effective treatment for patients with tumors causing TIO. This modality proves valuable when surgical resection is not a viable option.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Case Reports
    ISSN 2755-1520
    ISSN (online) 2755-1520
    DOI 10.1210/jcemcr/luae044
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