LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 29

Search options

  1. Book ; Conference proceedings: Sixteenth Conference on the Adrenal Cortex (Adrenal 2014)

    Schimmer, Bernard P.

    [Chicago, Illinois, June 17 - 20, 2014]

    (Molecular and cellular endocrinology ; 408,C = Special issue)

    2015  

    Event/congress Conference on the Adrenal Cortex (16., 2014, ChicagoIll.)
    Author's details guest ed: Bernard P. Schimmer
    Series title Molecular and cellular endocrinology ; 408,C = Special issue
    Collection
    Language English
    Size 248 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT018654323
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1127 -408- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Conference proceedings: Fourteenth Conference on the Adrenal Cortex (Adrenal 2010) and the Keith L. Parker Memorial Symposium

    Schimmer, Bernard P.

    San Diego, California, June 16 - 18, 2010

    (Molecular and cellular endocrinology ; 336,1/2 = Special issue)

    2011  

    Event/congress Conference on the Adrenal Cortex (14, 2010, SanDiegoCalif.) ; Keith L. Parker Memorial Symposium (2010, SanDiegoCalif.)
    Author's details guest ed: Bernard Schimmer
    Series title Molecular and cellular endocrinology ; 336,1/2 = Special issue
    Collection
    Language English
    Size S. 1 - 223 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT016757280
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1127 -336- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Conference proceedings: Thirteenth Conference on the Adrenal Cortex

    Schimmer, Bernard P.

    (Adrenal 2008) ; [Burlingame, CA from June 11 - 14, 2008]

    (Molecular and cellular endocrinology ; 300,1/2 = Special issue)

    2009  

    Event/congress Conference on the Adrenal Cortex (13, 2008, BurlingameCalif.)
    Author's details guest ed: Bernard Schimmer
    Series title Molecular and cellular endocrinology ; 300,1/2 = Special issue
    Collection
    Language English
    Size S. 1 - 204 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015864155
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1127 -300- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Book ; Conference proceedings: Adrenal, molecular steroidgenesis 2006 (AMS 2006)

    Schimmer, Bernard P.

    Boston, Massachusetts, June 20 - 23, 2006 ; [a joint meeting of The Adrenal Cortex Conference and The Molecular Steroidogenesis Workshop]

    (Molecular and cellular endocrinology ; 256/266, Feb. = Special issue)

    2007  

    Event/congress Adrenal Cortex Conference (2006, BostonMass.) ; Molecular Steroidogenesis Workshop (2006, BostonMass.)
    Author's details guest ed.: Bernard P. Schimmer
    Series title Molecular and cellular endocrinology ; 256/266, Feb. = Special issue
    Collection
    Language English
    Size S. 1 - S. 204 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015029308
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1127 -256/266- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Sixteenth conference on the adrenal cortex (Adrenal 2014), Chicago, Illinois, June 17-20, 2014.

    Schimmer, Bernard P

    Molecular and cellular endocrinology

    2015  Volume 408, Page(s) 1

    MeSH term(s) Adrenal Cortex/physiology ; Chicago ; Congresses as Topic ; Humans
    Language English
    Publishing date 2015-06-15
    Publishing country Ireland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2015.03.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online ; Conference proceedings: Preface: Fifteenth conference on the adrenal cortex (adrenal 2012) League City, Texas June 19-22, 2012.

    Schimmer, Bernard P

    Molecular and cellular endocrinology

    2013  Volume 371, Issue 1-2, Page(s) 1

    MeSH term(s) Adrenal Cortex ; Adrenal Glands ; Humans
    Language English
    Publishing date 2013-05-22
    Publishing country Ireland
    Document type Congresses ; Introductory Journal Article
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2013.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Seventeenth Conference on the Adrenal Cortex (Adrenal 2016) Boston, MA, March 28-31, 2016.

    Schimmer, Bernard P / Rodgers, Raymond J

    Molecular and cellular endocrinology

    2017  Volume 441, Page(s) 1

    Language English
    Publishing date 2017--05
    Publishing country Ireland
    Document type Editorial
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2016.12.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial.

    Beck-Schimmer, Beatrice / Schadde, Erik / Pietsch, Urs / Filipovic, Miodrag / Dübendorfer-Dalbert, Seraina / Fodor, Patricia / Hübner, Tobias / Schuepbach, Reto / Steiger, Peter / David, Sascha / Krüger, Bernard D / Neff, Thomas A / Schläpfer, Martin

    Annals of intensive care

    2024  Volume 14, Issue 1, Page(s) 41

    Abstract: ... control patients (p = 0.916) reaching the primary outcome. Five patients died within 28 days in each group ... 16% vs. 18%, p = 0.817). Of the 28-day survivors, 6 (26%) and 8 (30%) presented with POD (p = 0.781 ... in the sevoflurane arm, 7 (26%) in the control one (p = 0.028)). Length of ICU stay, hospital stay, and registered ...

    Abstract Background: This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung injury with invasive mechanical ventilation and sedation.
    Methods: This is a small-scale pilot multicenter randomized controlled trial from four tertiary hospitals in Switzerland, conducted between April 2020 and May 2021. 60 patients requiring mechanical ventilation due to severe COVID-19-related lung injury were included and randomized to 48-hour sedation with sevoflurane vs. continuous intravenous sedation (= control) within 24 h after intubation. The primary composite outcome was determined as mortality or persistent organ dysfunction (POD), defined as the need for mechanical ventilation, vasopressors, or renal replacement therapy at day 28. Secondary outcomes were the length of ICU and hospital stay, adverse events, routine laboratory parameters (creatinine, urea), and plasma inflammatory mediators.
    Results: 28 patients were randomized to sevoflurane, 32 to the control arm. The intention-to-treat analysis revealed no difference in the primary endpoint with 11 (39%) sevoflurane and 13 (41%) control patients (p = 0.916) reaching the primary outcome. Five patients died within 28 days in each group (16% vs. 18%, p = 0.817). Of the 28-day survivors, 6 (26%) and 8 (30%) presented with POD (p = 0.781). There was a significant difference regarding the need for vasopressors (1 (4%) patient in the sevoflurane arm, 7 (26%) in the control one (p = 0.028)). Length of ICU stay, hospital stay, and registered adverse events within 28 days were comparable, except for acute kidney injury (AKI), with 11 (39%) sevoflurane vs. 2 (6%) control patients (p = 0.001). The blood levels of IL-6 in the first few days after the onset of the lung injury were less distinctly elevated than expected.
    Conclusions: No evident benefits were observed with short sevoflurane sedation on mortality and POD. Unexpectedly low blood levels of IL-6 might indicate a moderate injury with therefore limited improvement options of sevoflurane. Acute renal issues suggest caution in using sevoflurane for sedation in COVID-19.
    Trial registration: The trial was registered on ClinicalTrials.gov (NCT04355962) on 2020/04/21.
    Language English
    Publishing date 2024-03-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-024-01276-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Corticotropin (ACTH) regulates alternative RNA splicing in Y1 mouse adrenocortical tumor cells.

    Schimmer, Bernard P / Cordova, Martha

    Molecular and cellular endocrinology

    2015  Volume 408, Page(s) 5–11

    Abstract: The stimulatory effect of ACTH on gene expression is well documented and is thought to be a major mechanism by which ACTH maintains the functional and structural integrity of the gland. Previously, we showed that ACTH regulates the accumulation of over ... ...

    Abstract The stimulatory effect of ACTH on gene expression is well documented and is thought to be a major mechanism by which ACTH maintains the functional and structural integrity of the gland. Previously, we showed that ACTH regulates the accumulation of over 1200 transcripts in Y1 adrenal cells, including a cluster with functions in alternative splicing of RNA. On this basis, we postulated that some of the effects of ACTH on the transcription landscape of Y1 cells are mediated by alternative splicing. In this study, we demonstrate that ACTH regulates the alternative splicing of four transcripts - Gnas, Cd151, Dab2 and Tia1. Inasmuch as alternative splicing potentially affects transcripts from more than two-thirds of the mouse genome, we suggest that these findings are representative of a genome-wide effect of ACTH that impacts on the mRNA and protein composition of the adrenal cortex.
    MeSH term(s) 8-Bromo Cyclic Adenosine Monophosphate/pharmacology ; Adrenal Cortex Neoplasms/genetics ; Adrenocorticotropic Hormone/pharmacology ; Alternative Splicing/drug effects ; Alternative Splicing/genetics ; Animals ; Base Sequence ; Cell Line, Tumor ; Colforsin/pharmacology ; Exons/genetics ; Humans ; Mice ; Molecular Sequence Data ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Second Messenger Systems/drug effects ; Signal Transduction/drug effects ; Tetradecanoylphorbol Acetate/pharmacology
    Chemical Substances RNA, Messenger ; Colforsin (1F7A44V6OU) ; 8-Bromo Cyclic Adenosine Monophosphate (23583-48-4) ; Adrenocorticotropic Hormone (9002-60-2) ; Tetradecanoylphorbol Acetate (NI40JAQ945)
    Language English
    Publishing date 2015-06-15
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2014.09.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Conference on the Adrenal Cortex 2008, Burlingame, CA June 11-14, 2008.

    Schimmer, Bernard P

    Molecular and cellular endocrinology

    2008  Volume 300, Issue 1-2, Page(s) 1

    MeSH term(s) Adrenal Cortex/physiology ; Congresses as Topic ; Disease ; Humans
    Language English
    Publishing date 2008-12-03
    Publishing country Ireland
    Document type Editorial
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2008.11.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top