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  1. Article: Characterization of Nonaflatoxigenic

    Jun, Sang-Cheol / Kim, Yu-Kyung / Han, Kap-Hoon

    Mycobiology

    2022  Volume 50, Issue 6, Page(s) 408–419

    Abstract: Filamentous fungi that could be classified ... ...

    Abstract Filamentous fungi that could be classified into
    Language English
    Publishing date 2022-12-29
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2631580-4
    ISSN 2092-9323 ; 1229-8093
    ISSN (online) 2092-9323
    ISSN 1229-8093
    DOI 10.1080/12298093.2022.2156139
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  2. Article ; Online: Correction: Emergence and genomic characterization of Proteus mirabilis harboring bla

    Kyung, Su Min / Lee, Jun Ho / Lee, Eun-Seo / Xiang, Xi-Rui / Yoo, Han Sang

    Veterinary research

    2024  Volume 55, Issue 1, Page(s) 55

    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Published Erratum
    ZDB-ID 1146298-x
    ISSN 1297-9716 ; 0928-4249
    ISSN (online) 1297-9716
    ISSN 0928-4249
    DOI 10.1186/s13567-024-01317-7
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  3. Article ; Online: Insufficient nutrient intake in individuals with disabling hearing loss and the restoration of nutritional sufficiency in hearing aid users.

    Han, Sang-Yoon / Lee, Sang-Yeon / Suh, Myung-Whan / Lee, Jun Ho / Park, Moo Kyun

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7509

    Abstract: Hearing loss affects some nutrient intake. Disabling hearing loss may exacerbate these issues. We aimed to evaluate nutrient intake and assess deficiencies based on functional hearing status. The study included 6907 participants with information on ... ...

    Abstract Hearing loss affects some nutrient intake. Disabling hearing loss may exacerbate these issues. We aimed to evaluate nutrient intake and assess deficiencies based on functional hearing status. The study included 6907 participants with information on demographic factors, nutrient intake, weight, height, disease status, and hearing level in the eighth Korea National Health and Nutrition Examination Survey, conducted from 2019 to 2021. We categorized the participants into 3 groups based on their functional hearing status: bilateral hearing, unilateral hearing, and disabling hearing loss. The disabling hearing loss group showed lower intake of most major nutrients (P < 0.05), dietary fiber (P < 0.001), and most minerals and vitamins (P < 0.05), with some insufficiencies. The unilateral hearing group showed lower intake only for potassium (P = 0.036) compared to the bilateral hearing group and significantly higher intake of hydration (P = 0.039), dietary fiber (P = 0.039), and calcium (P = 0.009) than the disabling hearing loss group. Nutrient insufficiency in the disabling hearing loss group was more prominent in women, and was partially resolved by using hearing aids. Clinicians and nutritionists should consider undernourishment in these patients, and appropriate interventions for nutrition and hearing aids should be recommended.
    MeSH term(s) Humans ; Female ; Nutrition Surveys ; Hearing Aids ; Hearing Loss ; Eating ; Deafness ; Dietary Fiber ; Diet
    Chemical Substances Dietary Fiber
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57927-w
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  4. Article ; Online: Wearable functional near-infrared spectroscopy for measuring dissociable activation dynamics of prefrontal cortex subregions during working memory.

    Shin, Jung Han / Kang, Min Jun / Lee, Sang Ah

    Human brain mapping

    2024  Volume 45, Issue 2, Page(s) e26619

    Abstract: The prefrontal cortex (PFC) has been extensively studied in relation to various cognitive abilities, including executive function, attention, and memory. Nevertheless, there is a gap in our scientific knowledge regarding the functionally dissociable ... ...

    Abstract The prefrontal cortex (PFC) has been extensively studied in relation to various cognitive abilities, including executive function, attention, and memory. Nevertheless, there is a gap in our scientific knowledge regarding the functionally dissociable neural dynamics across the PFC during a cognitive task and their individual differences in performance. Here, we explored this possibility using a delayed match-to-sample (DMTS) working memory (WM) task using NIRSIT, a high-density, wireless, wearable functional near-infrared spectroscopy (fNIRS) system. First, upon presentation of the sample stimulus, we observed an immediate signal increase in the ventral (orbitofrontal) region of the anterior PFC, followed by activity in the dorsolateral PFC. After the DMTS test stimulus appeared, the orbitofrontal cortex activated once again, while the rest of the PFC showed overall disengagement. Individuals with higher accuracy showed earlier and sustained activation of the PFC across the trial. Furthermore, higher network efficiency and functional connectivity in the PFC were correlated with individual WM performance. Our study sheds new light on the dynamics of PFC subregional activity during a cognitive task and its potential applicability in explaining individual differences in experimental, educational, or clinical populations. PRACTITIONER POINTS: Wearable functional near-infrared spectroscopy (fNIRS) captured dissociable temporal dynamics across prefrontal subregions during a delayed match-to-sample task. Anterior regions of the orbitofrontal cortex (OFC) activated first during the delay period, followed by the dorsolateral prefrontal cortex (PFC). PFC disengaged overall after the delay, but the OFC reactivated to the test stimulus. Earlier and sustained activation of PFC was associated with better accuracy. Functional connectivity and network efficiency also varied with task performance.
    MeSH term(s) Humans ; Memory, Short-Term/physiology ; Spectroscopy, Near-Infrared/methods ; Cognition/physiology ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/physiology ; Wearable Electronic Devices
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26619
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  5. Article ; Online: Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis.

    Chung, Monica S / Han, Sang Jun

    Frontiers in global women's health

    2022  Volume 3, Page(s) 856316

    Abstract: Endometriosis is a known estrogen-dependent inflammatory disease affecting reproductive-aged women. Common symptoms include pelvic pain, dysmenorrhea, dyspareunia, heavy menstrual bleeding, and infertility. The exact etiology of endometriosis is largely ... ...

    Abstract Endometriosis is a known estrogen-dependent inflammatory disease affecting reproductive-aged women. Common symptoms include pelvic pain, dysmenorrhea, dyspareunia, heavy menstrual bleeding, and infertility. The exact etiology of endometriosis is largely unknown, and, thus, the diagnosis and treatment of endometriosis are challenging. A complex interplay of many molecular mechanisms is thought to aid in the progression of endometriosis, most notably angiogenesis. This mini-review examines our current knowledge of the molecular etiology of endometriosis-associated angiogenesis and discusses anti-angiogenic therapy, in the blockade of endometriosis-associated angiogenesis, as potential non-hormonal therapy for the treatment of endometriosis.
    Language English
    Publishing date 2022-04-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-5059
    ISSN (online) 2673-5059
    DOI 10.3389/fgwh.2022.856316
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  6. Article ; Online: Interferon Signaling in the Endometrium and in Endometriosis.

    Park, Yuri / Han, Sang Jun

    Biomolecules

    2022  Volume 12, Issue 11

    Abstract: Endometriosis is an estrogen-dependent inflammatory disease that develops in reproductive-aged women who experience pelvic pain and infertility. Even though endometriosis is not a new disease, its molecular etiology has not been clearly elucidated. ... ...

    Abstract Endometriosis is an estrogen-dependent inflammatory disease that develops in reproductive-aged women who experience pelvic pain and infertility. Even though endometriosis is not a new disease, its molecular etiology has not been clearly elucidated. Defects in the immune system might be one of the factors that promote endometriosis progression. For example, elevated levels of proinflammatory cytokines are associated with endometriosis. Interferon is one of the cytokines that is elevated in endometriotic tissues compared with normal endometrium. Therefore, high interferon levels play a crucial role in endometriosis progression. In addition to endometriosis, however, interferon has a critical role in endometrial function, particularly in the initiation and maintenance of pregnancy. Therefore, this review describes the double-edged sword of interferon signaling in normal endometrial function versus endometriosis progression and also discusses interferon targeting as a new nonhormonal therapy for endometriosis. This approach may increase the efficacy of endometriosis treatment and reduce the adverse effects associated with current hormonal therapy for this disease.
    MeSH term(s) Pregnancy ; Female ; Humans ; Adult ; Endometriosis ; Endometrium ; Estrogens ; Cytokines ; Interferons
    Chemical Substances Estrogens ; Cytokines ; Interferons (9008-11-1)
    Language English
    Publishing date 2022-10-25
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom12111554
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  7. Article ; Online: Synbiotic Combination between

    Zhang, Tuo / Cheng, Tiantian / Geng, Shuo / Mao, Kemin / Li, Xiyu / Gao, Jie / Han, Jun / Sang, Yaxin

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 4, Page(s) 2214–2228

    Abstract: Previously, ...

    Abstract Previously,
    MeSH term(s) Animals ; Mice ; Synbiotics ; Lacticaseibacillus paracasei ; Dextran Sulfate/adverse effects ; Mannans ; Probiotics/pharmacology ; Stem Cell Niche ; Tryptophan ; Colitis/chemically induced ; Colitis/genetics ; Colitis/therapy ; Lactobacillus ; Oligosaccharides ; Anti-Bacterial Agents/adverse effects ; Disease Models, Animal ; Mice, Inbred C57BL ; Colon
    Chemical Substances Dextran Sulfate (9042-14-2) ; Mannans ; Tryptophan (8DUH1N11BX) ; Oligosaccharides ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c08473
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
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  8. Article: Baseline Correction of the Human

    Choi, Sang-Han / Ryu, Yeun-Chul / Chung, Jun-Young

    Metabolites

    2022  Volume 12, Issue 12

    Abstract: The baseline distortion caused by water and fat signals is a crucial issue in ... ...

    Abstract The baseline distortion caused by water and fat signals is a crucial issue in the
    Language English
    Publishing date 2022-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo12121257
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  9. Article: Philosophical strategies for nature of science based on worldviews: The quantum interference of single electron.

    Oh, Jun-Young / Son, Yeon-A / Han, Sang-Kil

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19331

    Abstract: This study aims to present a strategy to transform the worldviews of students, especially college science classrooms, into desirable current worldviews (Darwin, Quantum mechanics, Einstein, refer to Fig 1). Above all, the worldviews, that is metaphysical ...

    Abstract This study aims to present a strategy to transform the worldviews of students, especially college science classrooms, into desirable current worldviews (Darwin, Quantum mechanics, Einstein, refer to Fig 1). Above all, the worldviews, that is metaphysical belief, needs to be changed. This is because metaphysical belief is the basis for the whole framework of conception. Since the previous study emphasized epistemological belief only, an emphasis was placed on metaphysical belief on which epistemological belief is based. Therefore, the two beliefs should be used to elucidate in the education of Nature of Science. Metaphysical belief in the science of cosmic order, symmetry, or disorder is often important in scientific research and can lead to an epistemological view that can select or reject a certain kind of explanation. Specially, the two-slit experiment with single electrons is a radical illustration of another paradigm shift, from classical (mechanistic materialism) to quantum physics (desirable dialectical materialism). The double slit electron experiment creates sensuous images that can be grasped at once. Because quantum mechanics is inherently abstract, it is difficult to accept its meaning.
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19331
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  10. Article ; Online: Erratum: Correction of Tables in the Article "Reference Respiratory Muscle Strength Values and a Prediction Equation Using Physical Functions for Pulmonary Rehabilitation in Korea".

    Park, Tae Sung / Tak, Young Jin / Ra, Youngjin / Kim, Jinmi / Han, Sang Hun / Kim, Sang Hun / Shin, YongBeom / Shin, Myung-Jun / Kang, Jong Ho

    Journal of Korean medical science

    2024  Volume 39, Issue 6, Page(s) e78

    Abstract: This corrects the article on p. e325 in vol. 38, PMID: 37846788. ...

    Abstract This corrects the article on p. e325 in vol. 38, PMID: 37846788.
    Language English
    Publishing date 2024-02-19
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 639262-3
    ISSN 1598-6357 ; 1011-8934
    ISSN (online) 1598-6357
    ISSN 1011-8934
    DOI 10.3346/jkms.2024.39.e78
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