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  1. Article ; Online: A Rare Manifestation of Airway Invasion from Pulmonary Artery Liposarcoma.

    Miao, Jinrui / Tong, Run / Zhang, Yongming / Deng, Mingming / Bian, Yiding / Li, Ruixia / Hou, Gang

    American journal of respiratory and critical care medicine

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202308-1377IM
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detection and prediction of pathogenic microorganisms in aquaculture (Zhejiang Province, China).

    Zhao, Tong / Shen, Zhencai / Zhong, Ping / Zou, Hui / Han, Mingming

    Environmental science and pollution research international

    2024  Volume 31, Issue 5, Page(s) 8210–8222

    Abstract: The detection and prediction of pathogenic microorganisms play a crucial role in the sustainable development of the aquaculture industry. Currently, researchers mainly focus on the prediction of water quality parameters such as dissolved oxygen for early ...

    Abstract The detection and prediction of pathogenic microorganisms play a crucial role in the sustainable development of the aquaculture industry. Currently, researchers mainly focus on the prediction of water quality parameters such as dissolved oxygen for early warning. To provide early warning directly from the pathogenic source, this study proposes an innovative approach for the detection and prediction of pathogenic microorganisms based on yellow croaker aquaculture. Specifically, a method based on quantitative polymerase chain reaction (qPCR) is designed to detect the Cryptocaryon irritans (Cri) pathogenic microorganisms. Furthermore, we design a predictive combination model for small samples and high noise data to achieve early warning. After performing wavelet analysis to denoise the data, two data augmentation strategies are used to expand the dataset and then combined with the BP neural network (BPNN) to build the fusion prediction model. To ensure the stability of the detection method, we conduct repeatability and sensitivity tests on the designed qPCR detection technique. To verify the validity of the model, we compare the combined BPNN to long short-term memory (LSTM). The experimental results show that the qPCR method provides accurate quantitative measurement of Cri pathogenic microorganisms, and the combined model achieves a good level. The prediction model demonstrates higher accuracy in predicting Cri pathogenic microorganisms compared to the LSTM method, with evaluation indicators including mean absolute error (MAE), recall rate, and accuracy rate. Especially, the accuracy of early warning is increased by 54.02%.
    MeSH term(s) Animals ; Neural Networks, Computer ; Water Quality ; Aquaculture ; China ; Perciformes
    Language English
    Publishing date 2024-01-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-31612-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multipart Build Effects on Temperature and Residual Stress by Laser Beam Powder Bed Fusion Additive Manufacturing.

    Zhang, Wenyou / Tong, Mingming / Harrison, Noel M

    3D printing and additive manufacturing

    2023  Volume 10, Issue 4, Page(s) 749–761

    Abstract: Laser beam powder bed fusion (PBF-LB) is a leading technique among metal additive manufacturing (AM), and it has a wide range of applications in aerospace and medical devices. Most of the existing PBF-LB process modeling is mainly based on the ... ...

    Abstract Laser beam powder bed fusion (PBF-LB) is a leading technique among metal additive manufacturing (AM), and it has a wide range of applications in aerospace and medical devices. Most of the existing PBF-LB process modeling is mainly based on the fabrication of a single part on a large build plate, which is not reflective of the practical multipart PBF-LB manufacturing. The effects of batch size on the thermal and mechanical behavior of additively manufactured parts have not been investigated. In this work, the multipart PBF-LB thermomechanical modeling framework was proposed for the first time. The effects of sample numbers (1, 2, and 4) on temperature and residual stress (RS) of part-scale components were computationally investigated. It is found that RS within the parts decreased with increasing number of components per build. Parts located at the central areas of the build plate had larger RS than at the border. These findings can be beneficial for informing AM designers and operators of the optimum printing setup to minimize RS of metal parts in PBF-LB.
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Journal Article
    ISSN 2329-7670
    ISSN (online) 2329-7670
    DOI 10.1089/3dp.2021.0143
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  4. Article ; Online: Astaxanthin attenuates cigarette smoking-induced oxidative stress and inflammation in a sirtuin 1-dependent manner.

    Deng, Mingming / Tong, Run / Bian, Yiding / Hou, Gang

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2023  Volume 159, Page(s) 114230

    Abstract: Oxidative stress and chronic inflammation play key roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). Astaxanthin (AXT) is a keto-carotenoid with a variety of biological functions, including antioxidant and anti-inflammatory ... ...

    Abstract Oxidative stress and chronic inflammation play key roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). Astaxanthin (AXT) is a keto-carotenoid with a variety of biological functions, including antioxidant and anti-inflammatory effects This study aimed to explore the protective role and underlying mechanism of AXT in the pathogenesis of COPD. In this study, we found AXT alleviated pulmonary emphysema in a CS-exposed mouse model and regulated the expression of MMP-9/TIMP-1. And, AXT attenuates CSE-induced small airway fibrosis. Meanwhile, AXT inhibited Nrf2-modulated oxidative stress and the p65 NF-κB-regulated inflammatory pathway in both the mouse model and CSE-treated HBE cells. Mechanistically, AXT could directly bind to SIRT1 (the binding energy of the complex was -8.8 kcal/mol) and regulate the deacetylation activity of SIRT1. Finally, by activating SIRT1 deacetylation, AXT deacetylated Nrf2 and contributed to its action of reducing oxidative stress by generating antioxidant enzymes, and inhibiting p65 NF-κB transcriptional activity to suppress the inflammatory response. Our results show that treatment with AXT significantly reverses the oxidative stress and inflammation induced by cigarette smoke both in vivo and in vitro in a sirtuin 1-dependent manner.
    MeSH term(s) Mice ; Animals ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Sirtuin 1/metabolism ; Cigarette Smoking ; NF-kappa B/metabolism ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Inflammation/metabolism ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/metabolism ; Nicotiana ; Disease Models, Animal
    Chemical Substances Antioxidants ; Sirtuin 1 (EC 3.5.1.-) ; NF-kappa B ; astaxanthine (8XPW32PR7I) ; NF-E2-Related Factor 2
    Language English
    Publishing date 2023-01-23
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2023.114230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Corrigendum: Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.

    Tong, Fang / Xu, Lifa / Xu, Sheng / Zhang, Mingming

    Frontiers in genetics

    2022  Volume 13, Page(s) 1050296

    Abstract: This corrects the article DOI: 10.3389/fgene.2022.834935.]. ...

    Abstract [This corrects the article DOI: 10.3389/fgene.2022.834935.].
    Language English
    Publishing date 2022-10-25
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.1050296
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  6. Article: Computational modelling of dynamic recrystallisation of Ni-based superalloy during linear friction welding.

    Okeke, Saviour I / Harrison, Noel M / Tong, Mingming

    The International journal, advanced manufacturing technology

    2022  Volume 119, Issue 7-8, Page(s) 4461–4484

    Abstract: Linear friction welding (LFW) is an advanced joining technology used for manufacturing and repairing complex assemblies like blade integrated disks (blisks) of aeroengines. This paper presents an integrated multiphysics computational modelling for ... ...

    Abstract Linear friction welding (LFW) is an advanced joining technology used for manufacturing and repairing complex assemblies like blade integrated disks (blisks) of aeroengines. This paper presents an integrated multiphysics computational modelling for predicting the thermomechanical-microstructural processes of IN718 alloy (at the component-scale) during LFW. Johnson-Mehl-Avrami-Kolmogorov (JMAK) model was implemented for predicting the dynamic recrystallisation of
    Language English
    Publishing date 2022-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476510-X
    ISSN 1433-3015 ; 0268-3768
    ISSN (online) 1433-3015
    ISSN 0268-3768
    DOI 10.1007/s00170-021-08559-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Electron deficient Bi

    Su, Xiaojiang / Zhang, Xinyi / Gao, Mingming / Li, Xiao / Chang, Jin / Hu, Liangqing / Geng, Di / Ren, Yueming / Wei, Tong / Feng, Jing

    Journal of colloid and interface science

    2024  Volume 663, Page(s) 61–72

    Abstract: Efficient carriers separation and multiple nitrogen ( ... ...

    Abstract Efficient carriers separation and multiple nitrogen (N
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.02.130
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  8. Article: Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.

    Tong, Fang / Xu, Lifa / Xu, Sheng / Zhang, Mingming

    Frontiers in genetics

    2022  Volume 13, Page(s) 834935

    Abstract: ... Objective: ... To develop an autophagy-related lncRNA-based risk signature and corresponding nomogram to predict overall survival (OS) for LUAD patients and investigate the possible meaning of screened factors. ... Methods: ... Differentially expressed ...

    Abstract Objective: To develop an autophagy-related lncRNA-based risk signature and corresponding nomogram to predict overall survival (OS) for LUAD patients and investigate the possible meaning of screened factors. Methods: Differentially expressed lncRNAs and autophagy genes were screened between normal and LUAD tumor samples from the TCGA LUAD dataset. Univariate and multivariate Cox regression analyses were performed to construct the lncRNA-based risk signature and nomogram incorporating clinical information. Then, the accuracy and sensitivity were confirmed by the AUC of ROC curves in both training and validation cohorts. qPCR, immunoblot, shRNA, and ectopic expression were used to verify the positive regulation of NFYC-AS1 on BIRC6. CCK-8, immunofluorescence, and flow cytometry were used to confirm the influence of NFYC-AS1 on cell proliferation, autophagy, and apoptosis via BIRC6. Results: A 12-lncRNA risk signature and a nomogram combining related clinical information were constructed. Furthermore, the abnormal increase of NFYC-AS1 may promote LUAD progression through the autophagy-related gene BIRC6. Conclusion: 12-lncRNA signature may function as a predictive marker for LUAD patients, and NFYC-AS1 along with BIRC6 may function as carcinogenic factors in a combinatorial manner.
    Language English
    Publishing date 2022-08-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.834935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Nuclear miR-320 Controls Lipotoxicity.

    Tong, Mingming / Sadoshima, Junichi

    Circulation research

    2019  Volume 125, Issue 12, Page(s) 1121–1123

    MeSH term(s) Diabetes Mellitus ; Diabetic Cardiomyopathies ; Fatty Acids ; Heart ; Humans ; MicroRNAs
    Chemical Substances Fatty Acids ; MIRN320 microRNA, human ; MicroRNAs
    Language English
    Publishing date 2019-12-05
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.119.316199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effect Western Medicines Combined With Nao-Xue-Shu in Patients With Hypertensive Intracerebral Hemorrhage: A Network Meta-Analysis.

    Mei, Li / Fengqun, Mu / Xiaozhuo, Liu / Qing, Wang / Mingming, Fan / Zhengyao, Zuo / Dongpo, Su / Qian, Han / Tong, Chen

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 892904

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2022-06-15
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.892904
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