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Article ; Online: Commentary: Three-dimensional P3 tethering angle at the heart of future surgical decision making in ischemic mitral regurgitation.

Bouma, Wobbe / Gorman, Robert C

The Journal of thoracic and cardiovascular surgery

2018 Volume 157, Issue 5, Page(s) 1806–1807

MeSH term(s)	Coronary Artery Bypass ; Decision Making ; Humans ; Mitral Valve ; Mitral Valve Annuloplasty ; Mitral Valve Insufficiency
Language	English
Publishing date	2018-10-22
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2018.10.048
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Article: The worst MitraClip Scenario: acute mitral regurgitation due to papillary muscle rupture.

Carino, Davide / Denti, Paolo / Sala, Alessandra / Bouma, Wobbe / Castiglioni, Alessandro / Alfieri, Ottavio / Maisano, Francesco / De Bonis, Michele

Annals of cardiothoracic surgery

2022 Volume 11, Issue 3, Page(s) 340–342

Language	English
Publishing date	2022-06-13
Publishing country	China
Document type	Editorial
ZDB-ID	2713627-9
ISSN	2304-1021 ; 2225-319X
ISSN (online)	2304-1021
ISSN	2225-319X
DOI	10.21037/acs-2021-ami-11
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Article ; Online: Staged single-port thoracoscopic R2 sympathicotomy as a reproducible, safe and effective treatment option for debilitating severe facial blushing.

van der Weijde, Emma / Kuijpers, Michiel / Bouma, Wobbe / Mariani, Massimo A / Klinkenberg, Theo J

Interactive cardiovascular and thoracic surgery

2022 Volume 35, Issue 5

Abstract: Objectives: Our goal was to investigate the safety, feasibility, success rate, complication rate and side effects of staged single-port thoracoscopic R2 sympathicotomy in the treatment of severe facial blushing. Facial blushing is considered a benign ... ...

Abstract	Objectives: Our goal was to investigate the safety, feasibility, success rate, complication rate and side effects of staged single-port thoracoscopic R2 sympathicotomy in the treatment of severe facial blushing. Facial blushing is considered a benign condition; however, severe facial blushing can have a major impact on quality of life. When nonsurgical options such as medication and psychological treatments offer no or insufficient relief, surgical treatment with thoracoscopic sympathicotomy should be considered. Methods: All patients who underwent a staged thoracoscopic sympathicotomy at level R2 for severe facial blushing between January 2016 and September 2021 were included. Clinical and surgical data were prospectively collected and analysed. Results: A total of 16 patients with low operative risk (American Society of Anesthesiologists class 1) were treated. No major perioperative complications were encountered. One patient experienced postoperative unilateral Horner's syndrome that resolved completely after 1 week. Two patients experienced compensatory hyperhidrosis. The success rate was 100%. One patient experienced a slight recurrence of blushing symptoms after 3 years that did not interfere with their quality of life. All patients were satisfied with the results and had no regrets of having undergone the procedure. Conclusions: Staged single-port thoracoscopic R2 sympathicotomy is a reproducible, safe and highly effective surgical treatment option with low compensatory hyperhidrosis rates and the potential to significantly improve quality of life in carefully selected patients suffering from severe facial blushing. We would like to increase awareness among healthcare professionals for debilitating facial blushing and suggest timely referral for surgical treatment.
MeSH term(s)	Humans ; Blushing ; Hyperhidrosis/surgery ; Quality of Life ; Sympathectomy/adverse effects ; Sympathectomy/methods ; Treatment Outcome
Language	English
Publishing date	2022-10-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivac257
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Article ; Online: Reply.

Gorman, Robert C / Bouma, Wobbe / Gorman, Joseph H

The Annals of thoracic surgery

2016 Volume 102, Issue 4, Page(s) 1414–1415

Language	English
Publishing date	2016
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2016.04.084
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Article: Minimally Invasive Sympathicotomy for Palmar Hyperhidrosis and Facial Blushing: Current Status and the Hyperhidrosis Expert Center Approach.

Kuijpers, Michiel / van Zanden, Judith E / Harms, Petra W / Mungroop, Hubert E / Mariani, Massimo A / Klinkenberg, Theo J / Bouma, Wobbe

Journal of clinical medicine

2022 Volume 11, Issue 3

Abstract: Hyperhidrosis, the medical term for excessive sweating beyond physiological need, is a condition with serious emotional and social consequences for affected patients. Symptoms usually appear in focal areas such as the feet, hands, axillae and face. Non- ... ...

Abstract	Hyperhidrosis, the medical term for excessive sweating beyond physiological need, is a condition with serious emotional and social consequences for affected patients. Symptoms usually appear in focal areas such as the feet, hands, axillae and face. Non-surgical treatment options such as topical antiperspirants or systemic medications are usually offered as a first step of treatment, although these therapies are often ineffective, especially in severe and intolerable cases of hyperhidrosis. In the treatment algorithm for patients suffering from hyperhidrosis, surgical thoracoscopic sympathicotomy offers a permanent solution, which is particularly effective in the treatment of palmar hyperhidrosis and facial blushing. In this review, we describe the current status of thoracoscopic sympathicotomy for palmar hyperhidrosis and facial blushing. In addition, we share the specific treatment approach, technique and results of our Hyperhidrosis Expert Center. Last, we share recommendations to ensure an effective, reproducible and safe application of single-port thoracoscopic sympathicotomy for palmar hyperhidrosis and facial blushing, based on our extensive experience.
Language	English
Publishing date	2022-01-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11030786
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Article ; Online: Minimally Invasive Sympathicotomy for Palmar Hyperhidrosis and Facial Blushing

Michiel Kuijpers / Judith E. van Zanden / Petra W. Harms / Hubert E. Mungroop / Massimo A. Mariani / Theo J. Klinkenberg / Wobbe Bouma

Journal of Clinical Medicine, Vol 11, Iss 786, p

Current Status and the Hyperhidrosis Expert Center Approach

2022 Volume 786

Abstract	Hyperhidrosis, the medical term for excessive sweating beyond physiological need, is a condition with serious emotional and social consequences for affected patients. Symptoms usually appear in focal areas such as the feet, hands, axillae and face. Non-surgical treatment options such as topical antiperspirants or systemic medications are usually offered as a first step of treatment, although these therapies are often ineffective, especially in severe and intolerable cases of hyperhidrosis. In the treatment algorithm for patients suffering from hyperhidrosis, surgical thoracoscopic sympathicotomy offers a permanent solution, which is particularly effective in the treatment of palmar hyperhidrosis and facial blushing. In this review, we describe the current status of thoracoscopic sympathicotomy for palmar hyperhidrosis and facial blushing. In addition, we share the specific treatment approach, technique and results of our Hyperhidrosis Expert Center. Last, we share recommendations to ensure an effective, reproducible and safe application of single-port thoracoscopic sympathicotomy for palmar hyperhidrosis and facial blushing, based on our extensive experience.
Keywords	facial blushing ; palmar hyperhidrosis ; sympathectomy ; sympathicotomy ; endoscopic thoracic sympathectomy (ETS) ; single port video-assisted thoracoscopic surgery (VATS) ; Medicine ; R
Subject code	616
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Reply.

Bouma, Wobbe / Wijdh-den Hamer, Inez J / Gorman, Joseph H / Gorman, Robert C

The Annals of thoracic surgery

2018 Volume 106, Issue 1, Page(s) 313

MeSH term(s)	Humans ; Mitral Valve Annuloplasty ; Mitral Valve Insufficiency
Language	English
Publishing date	2018-02-09
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2018.01.029
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Article ; Online: Bilateral one-stage single-port sympathicotomy in primary focal hyperhidrosis, a prospective cohort study: treat earlier?

Kuijpers, Michiel / Peeters, Gwen / Harms, Petra W / Bouma, Wobbe / DeJongste, Mike J / Mariani, Massimo A / Klinkenberg, Theo J

Journal of cardiothoracic surgery

2021 Volume 16, Issue 1, Page(s) 50

Abstract: Background: Primary Focal Hyperhidrosis (PFH) has a detrimental effect on Quality of Life. Repetitive, non-curative symptomatic strategies dominate current treatment of PFH, in spite of the availability of an effective and permanent curative treatment ... ...

Abstract	Background: Primary Focal Hyperhidrosis (PFH) has a detrimental effect on Quality of Life. Repetitive, non-curative symptomatic strategies dominate current treatment of PFH, in spite of the availability of an effective and permanent curative treatment like Endoscopic Thoracic Sympathectomy (ETS). Current surgical optimization may allow for a re-established position of sympathetic modulation in this treatment algorithm. We sought to evaluate the safety, effectiveness, and long-term results of a Bilateral One-stage Single-port Sympathicotomy (BOSS) procedure in PFH patients and to identify subgroups benefitting most. Methods: Prospective analysis of 163 patients, 35 (21.5%) underwent Rib-3 (R3) BOSS for palmar PFH, 58 (35.6%) R3-R5 BOSS for axillary PFH and 70 (42.9%) R3-R5 BOSS for combined palmar/axillary PFH. Effectiveness was measured using Skindex-29 and the Hyperhidrosis Disease Severity Scale (HDSS). Results: Overall Skindex-29-rating (46.5 ± 14.8 preoperatively vs 20.1 ± 20.6 postoperatively, p < 0.001), and HDSS score (3.71 ± 0.45 preoperatively vs 1.82 ± 0.86 postoperatively, p < 0.001) indicated a significant improvement in health-related quality of life after BOSS. R3 BOSS was superior to R3-R5 BOSS in terms of HDSS score (1.49 vs 1.91 respectively, p = 0.004) and in terms of severe compensatory hyperhidrosis, a frequently reported side-effect (17.1% vs 32.8% respectively, p < 0.001). No major complications occurred. Conclusions: BOSS is safe, effective, and offers a long-term curative solution in the treatment of PFH. Especially in the palmar PFH subgroup, R3 BOSS treatment results compare favorably to the treatment results of non-curative alternatives published in the current literature. Therefore, R3 BOSS should be offered to all patients with severe PFH, reporting insufficient benefit of treatment options such as oral and/or local agents.
MeSH term(s)	Adolescent ; Adult ; Algorithms ; Axilla/surgery ; Endoscopy ; Female ; Humans ; Hyperhidrosis/psychology ; Hyperhidrosis/surgery ; Male ; Middle Aged ; Patient Safety ; Patient Satisfaction ; Postoperative Period ; Prospective Studies ; Quality of Life ; Surveys and Questionnaires ; Sympathectomy/methods ; Treatment Outcome
Language	English
Publishing date	2021-03-25
Publishing country	England
Document type	Journal Article
ISSN	1749-8090
ISSN (online)	1749-8090
DOI	10.1186/s13019-021-01430-0
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Article ; Online: Treatment of resistant Raynaud's phenomenon with single-port thoracoscopic sympathicotomy: One-year follow-up.

Kuijpers, Michiel / van de Zande, Saskia C / van Roon, Anniek M / van Roon, Arie M / Stel, Alja J / Smit, Andries J / Bouma, Wobbe / DeJongste, Mike J L / Mariani, Massimo A / Klinkenberg, Theo J / Mulder, Douwe J

Seminars in arthritis and rheumatism

2022 Volume 56, Page(s) 152065

Abstract: Objective: Follow-up of patients with treatment-resistant Raynaud's phenomenon (RP) one-year after single-port thoracoscopic sympathicotomy (SPTS).: Methods: Eight patients (six males, two females, median age of 45 years) with treatment-resistant RP ... ...

Abstract	Objective: Follow-up of patients with treatment-resistant Raynaud's phenomenon (RP) one-year after single-port thoracoscopic sympathicotomy (SPTS). Methods: Eight patients (six males, two females, median age of 45 years) with treatment-resistant RP underwent left-sided SPTS at the third rib (R3), unilaterally. Questionnaires were taken, and number and duration of RP attacks were reported over a 2-week period. Perfusion was assessed with a cooling and recovery procedure at baseline and one year after SPTS. Furthermore, laser speckle contrast analysis, pulse wave velocity, heart rate variability and nailfold capillary microscopy were performed. Results: One year after SPTS the duration of the attacks of was reduced with 1.9 h in the left hand versus 0.3 h in the right hand. Furthermore, three aspects of the questionnaire showed a significant improvement (role limitations due to physical health (p = 0.017), pain (p = 0.027) and physical functioning (p = 0.025)). The total area under the curve of the total cooling and recovery procedure of the left hand was larger one year after surgery (101 (75-140) at baseline versus 118 (95-190) one year post-operatively, p = 0.012), implying a better perfusion in the fingers. This was mainly due to the improvement during the recovery phase (21 (1-41) at baseline versus 38 (24-43) one year post-operatively, p = 0.028). Conclusion: One year after unilateral R3 SPTS the benefit with regard to the majority of outcome variables persisted, though some effects seem to attenuate. Long-term effects and long-term follow-up results will be investigated in an on-going study. Clinical trial registration number: NCT02680509.
MeSH term(s)	Capillaries ; Female ; Fingers/blood supply ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Pulse Wave Analysis ; Raynaud Disease/drug therapy ; Raynaud Disease/surgery
Language	English
Publishing date	2022-07-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	120247-9
ISSN	1532-866X ; 0049-0172
ISSN (online)	1532-866X
ISSN	0049-0172
DOI	10.1016/j.semarthrit.2022.152065
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Article ; Online: Mitral Valve Coaptation Reserve Index: A Model to Localize Individual Resistance to Mitral Regurgitation Caused by Annular Dilation.

Jainandunsing, Jayant S / Massari, Dario / Vos, Jaap Jan / Wijdh-den Hamer, Inez J / van den Heuvel, Ad Fm / Mariani, Massimo A / Mahmood, Feroze / Bouma, Wobbe / Scheeren, Thomas W L

Journal of cardiothoracic and vascular anesthesia

2022 Volume 37, Issue 5, Page(s) 690–697

Abstract: Objectives: The objective of this study was to develop a mathematical model for mitral annular dilatation simulation and determine its effects on the individualized mitral valve (MV) coaptation reserve index (CRI).: Design: A retrospective analysis ... ...

Abstract	Objectives: The objective of this study was to develop a mathematical model for mitral annular dilatation simulation and determine its effects on the individualized mitral valve (MV) coaptation reserve index (CRI). Design: A retrospective analysis of intraoperative transesophageal 3-dimensionalechocardiographic MV datasets was performed. A mathematical model was created to assess the mitral CRI for each leaflet segment (A1-P1, A2-P2, A3-P3). Mitral CRI was defined as the ratio between the coaptation reserve (measured coaptation length along the closure line) and an individualized correction factor. Indexing was chosen to correct for MV sphericity and area of largest valve opening. Mathematical models were created to simulate progressive mitral annular dilatation and to predict the effect on the individual mitral CRI. Setting: At a single-center academic hospital. Participants: Twenty-five patients with normally functioning MVs undergoing cardiac surgery. Interventions: None. Measurements and main results: Direct measurement of leaflet coaptation along the closure line showed the lowest amount of coaptation (reserve) near the commissures (A1-P1 0.21 ± 0.05 cm and A3-P3 0.22 ± 0.06 cm), and the highest amount of coaptation (reserve) at region A2 to P2 0.25 ± 0.06 cm. After indexing, the A2-to-P2 region was the area with the lowest CRI in the majority of patients, and also the area with the least resistance to mitral regurgitation (MR) occurrence after simulation of progressive annular dilation. Conclusions: Quantification and indexing of mitral coaptation reserve along the closure line are feasible. Indexing and mathematical simulation of progressive annular dilatation consistently showed that indexed coaptation reserve was lowest in the A2-to-P2 region. These results may explain why this area is prone to lose coaptation and is often affected in MR.
MeSH term(s)	Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/surgery ; Mitral Valve Insufficiency/etiology ; Dilatation ; Retrospective Studies ; Computer Simulation ; Echocardiography, Three-Dimensional/methods
Language	English
Publishing date	2022-11-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1067317-9
ISSN	1532-8422 ; 1053-0770
ISSN (online)	1532-8422
ISSN	1053-0770
DOI	10.1053/j.jvca.2022.11.009
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