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  1. Article: Moving Away From Randomized Controlled Trials to Hybrid Implementation Studies for Complex Interventions in the PICU.

    Ista, Erwin / van Dijk, Monique

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2024  Volume 25, Issue 2, Page(s) 177–180

    MeSH term(s) Child ; Humans ; Intensive Care Units, Pediatric ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000003400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Moving toward the Development and Effective Implementation of High-Quality Guidelines in Pediatric Surgery: A Review of the Literature.

    Irvine, Willemijn F E / Spivack, Olivia K C / Ista, Erwin

    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie

    2024  Volume 34, Issue 2, Page(s) 115–127

    Abstract: Applying evidence-based guidelines can enhance the quality of patient care. While robust guideline development methodology ensures credibility and validity, methodological variations can impact guideline quality. Besides methodological rigor, effective ... ...

    Abstract Applying evidence-based guidelines can enhance the quality of patient care. While robust guideline development methodology ensures credibility and validity, methodological variations can impact guideline quality. Besides methodological rigor, effective implementation is crucial for achieving improved health outcomes. This review provides an overview of recent literature pertaining to the development and implementation of guidelines in pediatric surgery. Literature was reviewed to provide an overview of sound guideline development methodologies and approaches to promote effective guideline implementation. Challenges specific to pediatric surgery were highlighted. A search was performed to identify published guidelines relevant to pediatric surgery from 2018 to June 2023, and their quality was collectively appraised using the AGREE II instrument. High-quality guideline development can be promoted by using methodologically sound tools such as the Guidelines 2.0 checklist, the GRADE system, and the AGREE II instrument. While implementation can be promoted during guideline development and post-publication, its effectiveness may be influenced by various factors. Challenges pertinent to pediatric surgery, such as limited evidence and difficulties with outcome selection and heterogeneity, may impact guideline quality and effective implementation. Fifteen guidelines were identified and collectively appraised as suboptimal, with a mean overall AGREE II score of 58%, with applicability being the lowest scoring domain. There are identified challenges and barriers to the development and effective implementation of high-quality guidelines in pediatric surgery. It is valuable to prioritize the identification of adapted, innovative methodological strategies and the use of implementation science to understand and achieve effective guideline implementation.
    MeSH term(s) Humans ; Pediatrics ; Practice Guidelines as Topic ; General Surgery/standards
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1065043-x
    ISSN 1439-359X ; 0939-7248 ; 0939-6764 ; 0930-7249
    ISSN (online) 1439-359X
    ISSN 0939-7248 ; 0939-6764 ; 0930-7249
    DOI 10.1055/s-0043-1778020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Mobility level and factors affecting mobility status in hospitalized patients admitted in single-occupancy patient rooms.

    Schafthuizen, Laura / van Dijk, Monique / van Rosmalen, Joost / Ista, Erwin

    BMC nursing

    2024  Volume 23, Issue 1, Page(s) 11

    Abstract: Background: Although stimulating patients' mobility is considered a component of fundamental nursing care, approximately 35% of hospitalized patients experience functional decline during or after hospital admission. The aim of this study is to assess ... ...

    Abstract Background: Although stimulating patients' mobility is considered a component of fundamental nursing care, approximately 35% of hospitalized patients experience functional decline during or after hospital admission. The aim of this study is to assess mobility level and to identify factors affecting mobility status in hospitalized patients admitted in single-occupancy patient rooms (SPRs) on general wards.
    Methods: Mobility level was quantified with the Johns Hopkins Highest Level of Mobility Scale (JH-HLM) and EQ-5D-3L. GENEActiv accelerometer data over 24 h were collected in a subset of patients. Data were analyzed using generalized ordinal logistic regression analysis. The STROBE reporting checklist was applied.
    Results: Wearing pajamas during daytime, having pain, admission in an isolation room, and wearing three or more medical equipment were negatively associated with mobilization level. More than half of patients (58.9%) who were able to mobilize according to the EQ-5D-3L did not achieve the highest possible level of mobility according to the JH-HLM. The subset of patients that wore an accelerometer spent most of the day in sedentary behavior (median 88.1%, IQR 85.9-93.6). The median total daily step count was 1326 (range 22-5362).
    Conclusion: We found that the majority of participating hospitalized patients staying in single-occupancy patient rooms were able to mobilize. It appeared, however, that most of the patients who are physically capable of walking, do not reach the highest possible level of mobility according to the JH-HLM scale. Nurses should take their responsibility to ensure that patients achieve the highest possible level of mobility.
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091496-9
    ISSN 1472-6955
    ISSN 1472-6955
    DOI 10.1186/s12912-023-01648-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Four-in-One: A Comprehensive Checklist for the Assessment of Pain, Undersedation, Iatrogenic Withdrawal and Delirium in the PICU: A Delphi Study.

    van Dijk, Monique / Ista, Erwin

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 887689

    Abstract: Objectives: Children's pain, undersedation, iatrogenic withdrawal syndrome and delirium often have overlapping symptoms, which makes it difficult to decide why a child in the PICU is not comfortable. Validated assessment tools for these conditions are ... ...

    Abstract Objectives: Children's pain, undersedation, iatrogenic withdrawal syndrome and delirium often have overlapping symptoms, which makes it difficult to decide why a child in the PICU is not comfortable. Validated assessment tools for these conditions are available, but regular assessment with multiple instruments may be too time-consuming. Therefore, we aimed to develop a new holistic instrument-the mosaIC checklist-that incorporates the assessment of the four conditions.
    Materials and methods: We conducted a two-rounds international Delphi study among experts working in PICUs worldwide to find cues that in combination or separately are relevant for the four conditions.
    Results: In the first Delphi round, 38 of the 48 enrolled participants (79%) completed a questionnaire; in the second round 32 of 48 (67%). Eventually, 46 cues in eight categories (e.g., facial, vocal/verbal, body movements, sleep /behavioral state, posture/muscle tone, agitation, physiological and contextual) were found relevant. Thirty-three (72%) were considered relevant for pain, 24 for undersedation (52%), 35 for iatrogenic withdrawal syndrome (76%) and 28 (61%) for pediatric delirium. Thirteen cues (28%) were considered relevant for all four conditions; 11's (24%) for only one condition.
    Conclusion: This Delphi study is the first step in developing a 4-in-1 comprehensive checklist to assess pain, undersedation, iatrogenic withdrawal syndrome and delirium in a holistic manner. Further validation is needed before the checklist can be applied in practice. Application of the mosaIC checklist could help determine what condition is most likely to cause a child's discomfort-and at the same time help reduce the PICU staff's registration burden.
    Language English
    Publishing date 2022-06-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.887689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Delirium in adult and paediatric ICU patients: what is the way forward?

    Ista, Erwin / Nydahl, Peter

    Nursing in critical care

    2021  Volume 26, Issue 3, Page(s) 147–149

    MeSH term(s) Adult ; Child ; Delirium/epidemiology ; Humans ; Intensive Care Units ; Intensive Care Units, Pediatric
    Language English
    Publishing date 2021-05-19
    Publishing country England
    Document type Editorial
    ZDB-ID 2011956-2
    ISSN 1478-5153 ; 1362-1017
    ISSN (online) 1478-5153
    ISSN 1362-1017
    DOI 10.1111/nicc.12629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Moving toward the Development and Effective Implementation of High-Quality Guidelines in Pediatric Surgery: A Review of the Literature

    Irvine, Willemijn F.E. / Spivack, Olivia K.C. / Ista, Erwin

    European Journal of Pediatric Surgery

    2024  Volume 34, Issue 02, Page(s) 115–127

    Abstract: Applying evidence-based guidelines can enhance the quality of patient care. While robust guideline development methodology ensures credibility and validity, methodological variations can impact guideline quality. Besides methodological rigor, effective ... ...

    Abstract Applying evidence-based guidelines can enhance the quality of patient care. While robust guideline development methodology ensures credibility and validity, methodological variations can impact guideline quality. Besides methodological rigor, effective implementation is crucial for achieving improved health outcomes. This review provides an overview of recent literature pertaining to the development and implementation of guidelines in pediatric surgery. Literature was reviewed to provide an overview of sound guideline development methodologies and approaches to promote effective guideline implementation. Challenges specific to pediatric surgery were highlighted. A search was performed to identify published guidelines relevant to pediatric surgery from 2018 to June 2023, and their quality was collectively appraised using the AGREE II instrument. High-quality guideline development can be promoted by using methodologically sound tools such as the Guidelines 2.0 checklist, the GRADE system, and the AGREE II instrument. While implementation can be promoted during guideline development and post-publication, its effectiveness may be influenced by various factors. Challenges pertinent to pediatric surgery, such as limited evidence and difficulties with outcome selection and heterogeneity, may impact guideline quality and effective implementation. Fifteen guidelines were identified and collectively appraised as suboptimal, with a mean overall AGREE II score of 58%, with applicability being the lowest scoring domain. There are identified challenges and barriers to the development and effective implementation of high-quality guidelines in pediatric surgery. It is valuable to prioritize the identification of adapted, innovative methodological strategies and the use of implementation science to understand and achieve effective guideline implementation.
    Keywords guideline ; methodology ; quality ; implementation ; pediatric surgery
    Language English
    Publishing date 2024-01-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1065043-x
    ISSN 1439-359X ; 0939-7248 ; 0939-6764 ; 0930-7249
    ISSN (online) 1439-359X
    ISSN 0939-7248 ; 0939-6764 ; 0930-7249
    DOI 10.1055/s-0043-1778020
    Database Thieme publisher's database

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  7. Article: The authors reply.

    Ista, Erwin / Traube, Chani / de Neef, Marjorie / Schieveld, Jan / Knoester, Hennie / Molag, Marja / Kudchadkar, Sapna R / Strik, Jacqueline

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2024  Volume 25, Issue 2, Page(s) e109–e110

    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000003402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Nurses' perceptions of the transition to 100% single-occupancy patient rooms in a university hospital in the Netherlands: an uncontrolled before and after study.

    Pruijsten, Ralph / Ista, Erwin / Maben, Jill / van Heel, Liesbeth / van Dijk, Monique

    BMC nursing

    2024  Volume 23, Issue 1, Page(s) 106

    Abstract: Background: To improve patients' privacy, comfort and infection control, newly built hospitals increasingly offer 100% single-occupancy patient rooms. Our study examines how nurses perceived the transition from a hospital with multi-bedded patient rooms ...

    Abstract Background: To improve patients' privacy, comfort and infection control, newly built hospitals increasingly offer 100% single-occupancy patient rooms. Our study examines how nurses perceived the transition from a hospital with multi-bedded patient rooms to one with solely single-occupancy patient rooms designed according to principles of a healing environment.
    Methods: In a single-centre, before-after survey study, nurses completed a questionnaire of 21 items in three domains: perceived patient safety and monitoring, nurses' working conditions and patient environment. Before-measurements (n = 217) were compared with two after-measurements in the new hospital, respectively after one (n = 483) and two years (n = 191).
    Results: Nurses considered the single rooms in the new hospital worse for visibility and monitoring but this had improved somewhat after two years. In either setting, the majority perceived working conditions (walking distances and designated rest area) as unfavourable. The patient environment in the new hospital was generally perceived as much better than in the former hospital.
    Conclusion: The transition to solely single-occupancy patient rooms was largely considered positive by nurses in terms of patient environment. However, monitoring of patients and working conditions remain a concern. When designing new hospitals, attention should be paid to optimal working conditions for nurses. To improve monitoring of patients, we recommend the use of remote-sensoring.
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091496-9
    ISSN 1472-6955
    ISSN 1472-6955
    DOI 10.1186/s12912-024-01758-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: High Incidence of Pediatric Delirium in PICU; Time for Action!

    Ista, Erwin / van Dijk, Monique

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2020  Volume 21, Issue 1, Page(s) 96–97

    MeSH term(s) Child ; Delirium ; Humans ; Incidence ; Intensive Care Units, Pediatric ; Risk Factors
    Language English
    Publishing date 2020-01-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000002166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The parent perspective on paediatric delirium and an associated care bundle: A qualitative study.

    Stenkjaer, Rikke Louise / Egerod, Ingrid / Moszkowicz, Mala / Collet, Marie Oxenbøll / Weis, Janne / Ista, Erwin / Greisen, Gorm / Herling, Suzanne Forsyth

    Journal of advanced nursing

    2024  

    Abstract: Aims: To explore how parents experienced their child with delirium and how parents viewed our delirium management bundle.: Design: We conducted a qualitative exploratory descriptive study using semi-structured individual or dyad interviews.: ... ...

    Abstract Aims: To explore how parents experienced their child with delirium and how parents viewed our delirium management bundle.
    Design: We conducted a qualitative exploratory descriptive study using semi-structured individual or dyad interviews.
    Methods: Twelve semi-structured interviews with 16 parents of 12 critically ill children diagnosed with delirium in a paediatric intensive care unit were conducted from October 2022 to January 2023 and analysed through a reflexive thematic analysis.
    Findings: We generated five themes: (1) knowing that something is very wrong, (2) observing manifest changes in the child, (3) experiencing fear of long-term consequences, (4) adding insight to the bundle, and (5) family engagement.
    Conclusion: The parents in our study were able to observe subtle and manifest changes in their child with delirium. This caused fear of lasting impact. The parents regarded most of the interventions in the delirium management bundle as relevant but needed individualization in the application. The parents requested more information regarding delirium and a higher level of parent engagement in the care of their child during delirium.
    Impact: This paper contributes to understanding how parents might experience delirium in their critically ill child, how our delirium management bundle was received by the parents, and their suggestions for improvement. Our study deals with critically ill children with delirium, their parents, and staff working to prevent and manage paediatric delirium (PD) in the paediatric intensive care unit.
    Reporting method: The consolidated criteria for reporting qualitative research guidelines were used to ensure the transparency of our reporting.
    Patient or public contribution: No patient or public contribution to the research design. WHAT DOES THIS PAPER CONTRIBUTE TO THE WIDER GLOBAL COMMUNITY?: - It increases awareness of the parent's perspective on PD in critically ill children. - It shows how PD might affect parents, causing negative emotions such as distress, frustration, and fear of permanent damage. - It shows that the parents in our study, in addition to the care bundle, requested more information on delirium and more involvement in the care of their delirious child.
    Language English
    Publishing date 2024-01-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.16048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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