LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 32

Search options

  1. Article ; Online: Improvement of Malicious Software Detection Accuracy through Genetic Programming Symbolic Classifier with Application of Dataset Oversampling Techniques

    Nikola Anđelić / Sandi Baressi Šegota / Zlatan Car

    Computers, Vol 12, Iss 12, p

    2023  Volume 242

    Abstract: Malware detection using hybrid features, combining binary and hexadecimal analysis with DLL calls, is crucial for leveraging the strengths of both static and dynamic analysis methods. Artificial intelligence (AI) enhances this process by enabling ... ...

    Abstract Malware detection using hybrid features, combining binary and hexadecimal analysis with DLL calls, is crucial for leveraging the strengths of both static and dynamic analysis methods. Artificial intelligence (AI) enhances this process by enabling automated pattern recognition, anomaly detection, and continuous learning, allowing security systems to adapt to evolving threats and identify complex, polymorphic malware that may exhibit varied behaviors. This synergy of hybrid features with AI empowers malware detection systems to efficiently and proactively identify and respond to sophisticated cyber threats in real time. In this paper, the genetic programming symbolic classifier (GPSC) algorithm was applied to the publicly available dataset to obtain symbolic expressions (SEs) that could detect the malware software with high classification performance. The initial problem with the dataset was a high imbalance between class samples, so various oversampling techniques were utilized to obtain balanced dataset variations on which GPSC was applied. To find the optimal combination of GPSC hyperparameter values, the random hyperparameter value search method (RHVS) was developed and applied to obtain SEs with high classification accuracy. The GPSC was trained with five-fold cross-validation (5FCV) to obtain a robust set of SEs on each dataset variation. To choose the best SEs, several evaluation metrics were used, i.e., the length and depth of SEs, accuracy score (ACC), area under receiver operating characteristic curve (AUC), precision, recall, f1-score, and confusion matrix. The best-obtained SEs are applied on the original imbalanced dataset to see if the classification performance is the same as it was on balanced dataset variations. The results of the investigation showed that the proposed method generated SEs with high classification accuracy (0.9962) in malware software detection.
    Keywords genetic programming symbolic classifier ; 5-fold cross-validation ; malware software detection ; oversampling techniques ; random hyperparameter value search method ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article: On Approximating the

    Baressi Šegota, Sandi / Lorencin, Ivan / Kovač, Zoran / Car, Zlatan

    Biomedicines

    2023  Volume 11, Issue 2

    Abstract: In the case of pandemics such as COVID-19, the rapid development of medicines addressing the symptoms is necessary to alleviate the pressure on the medical system. One of the key steps in medicine evaluation is the determination of pIC50 factor, which is ...

    Abstract In the case of pandemics such as COVID-19, the rapid development of medicines addressing the symptoms is necessary to alleviate the pressure on the medical system. One of the key steps in medicine evaluation is the determination of pIC50 factor, which is a negative logarithmic expression of the half maximal inhibitory concentration (IC50). Determining this value can be a lengthy and complicated process. A tool allowing for a quick approximation of pIC50 based on the molecular makeup of medicine could be valuable. In this paper, the creation of the artificial intelligence (AI)-based model is performed using a publicly available dataset of molecules and their pIC50 values. The modeling algorithms used are artificial and convolutional neural networks (ANN and CNN). Three approaches are tested-modeling using just molecular properties (MP), encoded SMILES representation of the molecule, and the combination of both input types. Models are evaluated using the coefficient of determination (R2) and mean absolute percentage error (MAPE) in a five-fold cross-validation scheme to assure the validity of the results. The obtained models show that the highest quality regression (R2¯=0.99, σR2¯=0.001; MAPE¯=0.009%, σMAPE¯=0.009), by a large margin, is obtained when using a hybrid neural network trained with both MP and SMILES.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11020284
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Localization and Classification of Venusian Volcanoes Using Image Detection Algorithms.

    Đuranović, Daniel / Baressi Šegota, Sandi / Lorencin, Ivan / Car, Zlatan

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: Imaging is one of the main tools of modern astronomy-many images are collected each day, and they must be processed. Processing such a large amount of images can be complex, time-consuming, and may require advanced tools. One of the techniques that may ... ...

    Abstract Imaging is one of the main tools of modern astronomy-many images are collected each day, and they must be processed. Processing such a large amount of images can be complex, time-consuming, and may require advanced tools. One of the techniques that may be employed is artificial intelligence (AI)-based image detection and classification. In this paper, the research is focused on developing such a system for the problem of the Magellan dataset, which contains 134 satellite images of Venus's surface with individual volcanoes marked with circular labels. Volcanoes are classified into four classes depending on their features. In this paper, the authors apply the You-Only-Look-Once (YOLO) algorithm, which is based on a convolutional neural network (CNN). To apply this technique, the original labels are first converted into a suitable YOLO format. Then, due to the relatively small number of images in the dataset, deterministic augmentation techniques are applied. Hyperparameters of the YOLO network are tuned to achieve the best results, which are evaluated as mean average precision (mAP@0.5) for localization accuracy and F1 score for classification accuracy. The experimental results using cross-vallidation indicate that the proposed method achieved 0.835 mAP@0.5 and 0.826 F1 scores, respectively.
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031224
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Automated Detection and Classification of Returnable Packaging Based on YOLOV4 Algorithm

    Matko Glučina / Sandi Baressi Šegota / Nikola Anđelić / Zlatan Car

    Applied Sciences, Vol 12, Iss 11131, p

    2022  Volume 11131

    Abstract: This article describes the implementation of the You Only Look Once (YOLO) detection algorithm for the detection of returnable packaging. The method of creating an original dataset and creating an augmented dataset is shown. The model was evaluated using ...

    Abstract This article describes the implementation of the You Only Look Once (YOLO) detection algorithm for the detection of returnable packaging. The method of creating an original dataset and creating an augmented dataset is shown. The model was evaluated using mean Average Precision (mAP), F1 <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mi>score</mi></msub></semantics></math> , Precision, Recall, Average Intersection over Union (Average IoU) score, and Average Loss. The training was conducted in four cycles, i.e., 6000, 8000, 10,000, and 20,000 max batches with three different activation functions Mish, ReLU, and Linear (used in 6000 and 8000 max batches). The influence train/test dataset ratio was also investigated. The conducted investigation showed that variation of hyperparameters (activation function and max batch sizes) have a significant influence on detection and classification accuracy with the best results obtained in the case of YOLO version 4 (YOLOV4) with the Mish activation function and max batch size of 20,000 that achieved the highest mAP of 99.96% and lowest average error of 0.3643.
    Keywords artificial intelligence algorithms ; automated system ; convolutional neural network ; computer vision ; YOLOV4 ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 006
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: The Development of Symbolic Expressions for the Detection of Hepatitis C Patients and the Disease Progression from Blood Parameters Using Genetic Programming-Symbolic Classification Algorithm

    Nikola Anđelić / Ivan Lorencin / Sandi Baressi Šegota / Zlatan Car

    Applied Sciences, Vol 13, Iss 1, p

    2022  Volume 574

    Abstract: Hepatitis C is an infectious disease which is caused by the Hepatitis C virus (HCV) and the virus primarily affects the liver. Based on the publicly available dataset used in this paper the idea is to develop a mathematical equation that could be used to ...

    Abstract Hepatitis C is an infectious disease which is caused by the Hepatitis C virus (HCV) and the virus primarily affects the liver. Based on the publicly available dataset used in this paper the idea is to develop a mathematical equation that could be used to detect HCV patients with high accuracy based on the enzymes, proteins, and biomarker values contained in a patient’s blood sample using genetic programming symbolic classification (GPSC) algorithm. Not only that, but the idea was also to obtain a mathematical equation that could detect the progress of the disease i.e., Hepatitis C, Fibrosis, and Cirrhosis using the GPSC algorithm. Since the original dataset was imbalanced (a large number of healthy patients versus a small number of Hepatitis C/Fibrosis/Cirrhosis patients) the dataset was balanced using random oversampling, SMOTE, ADSYN, and Borderline SMOTE methods. The symbolic expressions (mathematical equations) were obtained using the GPSC algorithm using a rigorous process of 5-fold cross-validation with a random hyperparameter search method which had to be developed for this problem. To evaluate each symbolic expression generated with GPSC the mean and standard deviation values of accuracy (ACC), the area under the receiver operating characteristic curve ( <semantics> A U C </semantics> ), precision, recall, and F1-score were obtained. In a simple binary case (healthy vs. Hepatitis C patients) the best case was achieved with a dataset balanced with the Borderline SMOTE method. The results are <semantics> A C C ¯ ± S D ( A C C ) </semantics> , <semantics> A U C ¯ ± S D ( A U C ) </semantics> , <semantics> P r e c i s i o n ¯ ± S D ( P r e c i s i o n ) </semantics> , <semantics> R e c a l l ¯ ± S D ( R e c a l l ) </semantics> , and <semantics> F 1 − s c o r e ¯ ± S D ( F 1 − s c o r e ) </semantics> equal to <semantics> 0.99 ± 5.8 × 10 − 3 </semantics> , <semantics> 0.99 ± 5.4 × 10 − 3 </semantics> , ...
    Keywords ADASYN ; borderline SMOTE ; genetic programming-symbolic classifier ; Hepatitis C ; fibrosis ; cirrhosis ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 511
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Book ; Conference proceedings: International Conference on Innovative Technologies

    Car, Zlatan

    IN-TECH 2012, Rijeka, [26. - 28.09.2012] ; proceedings

    2012  

    Title variant $3260 ; Proceedings of International Conference on Innovative Technologies IN-TECH
    Institution International Conference on Innovative Technologies
    Event/congress IN-TECH (2012.09.26-28, Rijeka) ; International Conference on Innovative Technologies (2012.09.26-28, Rijeka)
    Author's details [ed.: Zlatan Car ...]
    Language English
    Size 594 S., Ill., graph. Darst.
    Publisher Faculty of Engineering
    Publishing place Rijeka
    Document type Book ; Conference proceedings
    Note Literaturangaben
    ISBN 9789536326778 ; 9536326779
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  7. Article ; Online: Estimation of COVID-19 epidemic curves using genetic programming algorithm.

    Anđelić, Nikola / Baressi Šegota, Sandi / Lorencin, Ivan / Mrzljak, Vedran / Car, Zlatan

    Health informatics journal

    2021  Volume 27, Issue 1, Page(s) 1460458220976728

    Abstract: This paper investigates the possibility of the implementation of Genetic Programming (GP) algorithm on a publicly available COVID-19 data set, in order to obtain mathematical models which could be used for estimation of confirmed, deceased, and recovered ...

    Abstract This paper investigates the possibility of the implementation of Genetic Programming (GP) algorithm on a publicly available COVID-19 data set, in order to obtain mathematical models which could be used for estimation of confirmed, deceased, and recovered cases and the estimation of epidemiology curve for specific countries, with a high number of cases, such as China, Italy, Spain, and USA and as well as on the global scale. The conducted investigation shows that the best mathematical models produced for estimating confirmed and deceased cases achieved
    MeSH term(s) Algorithms ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/mortality ; Epidemics ; Epidemiologic Methods ; Humans ; Machine Learning ; Models, Theoretical ; SARS-CoV-2
    Language English
    Publishing date 2021-02-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2213115-2
    ISSN 1741-2811 ; 1460-4582
    ISSN (online) 1741-2811
    ISSN 1460-4582
    DOI 10.1177/1460458220976728
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Using multi-layer perceptron with Laplacian edge detector for bladder cancer diagnosis.

    Lorencin, Ivan / Anđelić, Nikola / Španjol, Josip / Car, Zlatan

    Artificial intelligence in medicine

    2019  Volume 102, Page(s) 101746

    Abstract: In this paper, the urinary bladder cancer diagnostic method which is based on Multi-Layer Perceptron and Laplacian edge detector is presented. The aim of this paper is to investigate the implementation possibility of a simpler method (Multi-Layer ... ...

    Abstract In this paper, the urinary bladder cancer diagnostic method which is based on Multi-Layer Perceptron and Laplacian edge detector is presented. The aim of this paper is to investigate the implementation possibility of a simpler method (Multi-Layer Perceptron) alongside commonly used methods, such as Deep Learning Convolutional Neural Networks, for the urinary bladder cancer detection. The dataset used for this research consisted of 1997 images of bladder cancer and 986 images of non-cancer tissue. The results of the conducted research showed that using Multi-Layer Perceptron trained and tested with images pre-processed with Laplacian edge detector are achieving AUC value up to 0.99. When different image sizes are compared it can be seen that the best results are achieved if 50×50 and 100×100 images were used.
    MeSH term(s) Algorithms ; Area Under Curve ; Artificial Intelligence ; Cystoscopy ; Databases, Factual ; Deep Learning ; Humans ; Image Interpretation, Computer-Assisted ; Neural Networks, Computer ; Urinary Bladder/diagnostic imaging ; Urinary Bladder Neoplasms/diagnosis ; Urinary Bladder Neoplasms/diagnostic imaging
    Language English
    Publishing date 2019-11-13
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645179-2
    ISSN 1873-2860 ; 0933-3657
    ISSN (online) 1873-2860
    ISSN 0933-3657
    DOI 10.1016/j.artmed.2019.101746
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: An Enhanced Histopathology Analysis: An AI-Based System for Multiclass Grading of Oral Squamous Cell Carcinoma and Segmenting of Epithelial and Stromal Tissue.

    Musulin, Jelena / Štifanić, Daniel / Zulijani, Ana / Ćabov, Tomislav / Dekanić, Andrea / Car, Zlatan

    Cancers

    2021  Volume 13, Issue 8

    Abstract: Oral squamous cell carcinoma is most frequent histological neoplasm of head and neck cancers, and although it is localized in a region that is accessible to see and can be detected very early, this usually does not occur. The standard procedure for the ... ...

    Abstract Oral squamous cell carcinoma is most frequent histological neoplasm of head and neck cancers, and although it is localized in a region that is accessible to see and can be detected very early, this usually does not occur. The standard procedure for the diagnosis of oral cancer is based on histopathological examination, however, the main problem in this kind of procedure is tumor heterogeneity where a subjective component of the examination could directly impact patient-specific treatment intervention. For this reason, artificial intelligence (AI) algorithms are widely used as computational aid in the diagnosis for classification and segmentation of tumors, in order to reduce inter- and intra-observer variability. In this research, a two-stage AI-based system for automatic multiclass grading (the first stage) and segmentation of the epithelial and stromal tissue (the second stage) from oral histopathological images is proposed in order to assist the clinician in oral squamous cell carcinoma diagnosis. The integration of Xception and SWT resulted in the highest classification value of 0.963 (σ = 0.042) AUCmacro and 0.966 (σ = 0.027) AUCmicro while using DeepLabv3+ along with Xception_65 as backbone and data preprocessing, semantic segmentation prediction resulted in 0.878 (σ = 0.027) mIOU and 0.955 (σ = 0.014) F1 score. Obtained results reveal that the proposed AI-based system has great potential in the diagnosis of OSCC.
    Language English
    Publishing date 2021-04-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13081784
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Utilization of multilayer perceptron for determining the inverse kinematics of an industrial robotic manipulator

    Sandi Baressi Šegota / Nikola Anđelić / Vedran Mrzljak / Ivan Lorencin / Ivan Kuric / Zlatan Car

    International Journal of Advanced Robotic Systems, Vol

    2021  Volume 18

    Abstract: Inverse kinematic equations allow the determination of the joint angles necessary for the robotic manipulator to place a tool into a predefined position. Determining this equation is vital but a complex work. In this article, an artificial neural network, ...

    Abstract Inverse kinematic equations allow the determination of the joint angles necessary for the robotic manipulator to place a tool into a predefined position. Determining this equation is vital but a complex work. In this article, an artificial neural network, more specifically, a feed-forward type, multilayer perceptron (MLP), is trained, so that it could be used to calculate the inverse kinematics for a robotic manipulator. First, direct kinematics of a robotic manipulator are determined using Denavit–Hartenberg method and a dataset of 15,000 points is generated using the calculated homogenous transformation matrices. Following that, multiple MLPs are trained with 10,240 different hyperparameter combinations to find the best. Each trained MLP is evaluated using the R 2 and mean absolute error metrics and the architectures of the MLPs that achieved the best results are presented. Results show a successful regression for the first five joints (percentage error being less than 0.1%) but a comparatively poor regression for the final joint due to the configuration of the robotic manipulator.
    Keywords Electronics ; TK7800-8360 ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 629
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top