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  1. Book ; Thesis: Der Einfluss von UVA-Strahlung auf die Expression des vaskulären Permeabilitätsfaktors (VEGF/VPF) durch HaCaT Keratinozyten

    Asbe-Vollkopf, Aida

    2003  

    Author's details vorgelegt von Aida Asbe-Vollkopf
    Language German
    Size 45 S. : Ill.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2004
    HBZ-ID HT014028582
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: CD4

    Freiwald, Tilo / Büttner, Stefan / Cheru, Nardos T / Avaniadi, Despina / Martin, Simon S / Stephan, Christoph / Pliquett, Rainer U / Asbe-Vollkopf, Aida / Schüttfort, Gundolf / Jacobi, Volkmar / Herrmann, Eva / Geiger, Helmut / Hauser, Ingeborg A

    Clinical transplantation

    2020  Volume 34, Issue 9, Page(s) e13877

    Abstract: Background: Pneumocystis jirovecii pneumonia (PcP) remains a life-threatening opportunistic infection after solid organ transplantation, even in the era of Pneumocystis prophylaxis. The association between risk of developing PcP and low CD4: Methods: ...

    Abstract Background: Pneumocystis jirovecii pneumonia (PcP) remains a life-threatening opportunistic infection after solid organ transplantation, even in the era of Pneumocystis prophylaxis. The association between risk of developing PcP and low CD4
    Methods: We carried out a retrospective analysis of a cohort of kidney transplant patients with PcP (n = 49) to determine the risk factors for mortality associated with PcP. We correlated clinical and demographic data with the outcome of the disease. For CD4
    Results: In univariate analyses, high CRP, high neutrophils, CD4
    Conclusions: Low CD4
    MeSH term(s) CD4-Positive T-Lymphocytes ; Humans ; Kidney Transplantation/adverse effects ; Lymphopenia/etiology ; Pneumocystis carinii ; Pneumonia, Pneumocystis/etiology ; Retrospective Studies
    Language English
    Publishing date 2020-04-30
    Publishing country Denmark
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.13877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Untersuchungen zum Oxidationsverhalten von Silizium

    Vollkopf, Alexander

    Einfluß auf die Aperturgeometrie von SiO2-Hohlspitzen

    2001  

    Author's details von Alexander Vollkopf
    Language German
    Size IV, 81 S, Ill., graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ.-Gesamthochsch., Diss.--Kassel, 2001
    Database Former special subject collection: coastal and deep sea fishing

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  4. Book ; Thesis: Untersuchungen zum Oxidationsverhalten von Silizium

    Vollkopf, Alexander

    Einfluß auf die Aperturgeometrie von SiO2-Hohlspitzen

    2001  

    Author's details von Alexander Vollkopf
    Language German
    Size IV, 81 S, Ill., graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ.-Gesamthochsch., Diss.--Kassel, 2001
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Article ; Online: How to Prevent Renal Cachexia? A Clinical Randomized Pilot Study Testing Oral Supplemental Nutrition in Hemodialysis Patients With and Without Human Immunodeficiency Virus Infection.

    Zilles, Michael / Betz, Christoph / Jung, Oliver / Gauer, Stefan / Hammerstingl, Renate / Wächtershäuser, Astrid / Vogl, Thomas J / Geiger, Helmut / Asbe-Vollkopf, Aida / Pliquett, Rainer U

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

    2017  Volume 28, Issue 1, Page(s) 37–44

    Abstract: Objective: End-stage renal disease associates with catabolism and sarcopenia. Hypothetically, peroral supplemental nutrition over 6 months prevents catabolism in hemodialysis patients.: Design: Prospective randomized pilot study (ClinicalTrials.gov ... ...

    Abstract Objective: End-stage renal disease associates with catabolism and sarcopenia. Hypothetically, peroral supplemental nutrition over 6 months prevents catabolism in hemodialysis patients.
    Design: Prospective randomized pilot study (ClinicalTrials.gov Identifier: NCT00687050).
    Subjects: Twenty-three hemodialysis patients (15 males and 7 females) with or without human immunodeficiency virus (HIV) infection of 2 ambulatory hemodialysis centers.
    Intervention: HIV-positive hemodialysis patients (n = 7, Group 1) were started on supplemental nutrition drinks (250 kcal/day), HIV-negative hemodialysis patients (n = 16, Group 2) were randomized to supplemental nutrition drinks (250 kcal/day) or received none.
    Main outcome measures: Body impedance analysis, anthropometric measures, magnetic resonance imaging results for mid-iliopsoas muscle cross-sectional area and laboratory parameters including albumin, cytokines at baseline, and at 6 months follow-up.
    Results: Seven patients in Group 1 (mean age: 50.6 ± 9.6 years) and 16 patients in Group 2 (mean age: 54.0 ± 13.3 years) were recruited. Serum creatinine (Group 1: 6.4 ± 3.0 mg/dL; Group 2: 10.7 ± 2.5 mg/dL; P < .01), Body impedance analysis-derived phase angle alpha (Group 1: 5.1 ± 1.2; Group 2: 6.9 ± 1.6; P < .01), mid-arm circumference (Group 1: 26.1 ± 1.3 cm; Group 2: 29.6 ± 2.4 cm; P < .01) were less in Group 1 versus Group 2 patients at baseline suggesting that HIV-positive hemodialysis patients had a poorer nutritional status at baseline. At 6-month follow-up, mortality was higher in Group 1 patients (29%) than in Group 2 patients (6%). There was no significant treatment effect on nutritional status in survivors of Group 1 or in the supplemental nutrition arm of Group 2 when compared with baseline or to untreated controls.
    Conclusions: A new oral supplemental nutrition over 6 months had no treatment effect in surviving HIV-positive hemodialysis patients or in maintenance hemodialysis patients without HIV infection. The limitations of this study were small study size and unexpected high mortality among HIV-positive hemodialysis patients.
    MeSH term(s) Adolescent ; Adult ; Aged ; Body Composition ; C-Reactive Protein/metabolism ; Cachexia/complications ; Cachexia/prevention & control ; Electric Impedance ; Female ; Follow-Up Studies ; HIV Infections/complications ; HIV Infections/therapy ; Humans ; Interleukin-1beta/blood ; Interleukin-6/blood ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Muscle, Skeletal/metabolism ; Nutrition Assessment ; Nutritional Status ; Nutritional Support ; Pilot Projects ; Prospective Studies ; Renal Dialysis/adverse effects ; Sarcopenia/complications ; Sarcopenia/prevention & control ; Serum Albumin/metabolism ; Tumor Necrosis Factor-alpha/blood ; Young Adult
    Chemical Substances IL1B protein, human ; IL6 protein, human ; Interleukin-1beta ; Interleukin-6 ; Serum Albumin ; Tumor Necrosis Factor-alpha ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2017-11-14
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1080003-7
    ISSN 1532-8503 ; 1051-2276
    ISSN (online) 1532-8503
    ISSN 1051-2276
    DOI 10.1053/j.jrn.2017.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Posttransplant Kaposi sarcoma and risk for deep venous thrombosis: a case-control study.

    Pliquett, Rainer U / Schöfer, Helmut / Asbe-Vollkopf, Aida / Hauser, Ingeborg A / Scheuermann, Ernst H / Kachel, Heinz-Georg

    Transplantation

    2011  Volume 91, Issue 4, Page(s) e21–2

    MeSH term(s) Adult ; Calcineurin Inhibitors ; Case-Control Studies ; Female ; Graft Survival/drug effects ; Humans ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation/adverse effects ; Middle Aged ; Mycophenolic Acid/analogs & derivatives ; Mycophenolic Acid/therapeutic use ; Prednisone/therapeutic use ; Risk ; Sarcoma, Kaposi/complications ; Sarcoma, Kaposi/diagnosis ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Treatment Outcome ; Venous Thrombosis/etiology
    Chemical Substances Calcineurin Inhibitors ; Immunosuppressive Agents ; MTOR protein, human (EC 2.7.1.1) ; TOR Serine-Threonine Kinases (EC 2.7.1.1) ; Mycophenolic Acid (HU9DX48N0T) ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2011-02-27
    Publishing country United States
    Document type Letter
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0b013e318205b3e5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pretransplant human leukocyte antigen antibodies detected by single-antigen bead assay are a risk factor for long-term kidney graft loss even in the absence of donor-specific antibodies.

    Richter, Rudolf / Süsal, Caner / Köhler, Stefanie / Qidan, Sara / Schödel, Alicia / Holschuh, Lisa / Brzoska, Martin / Asbe-Vollkopf, Aida / Büttner, Stefan / Betz, Christoph / Herrmann, Eva / Gauer, Stefan / Seifried, Erhard / Geiger, Helmut / Seidl, Christian / Hauser, Ingeborg A

    Transplant international : official journal of the European Society for Organ Transplantation

    2016  Volume 29, Issue 9, Page(s) 988–998

    Abstract: Clinical relevance of ELISA- and single-antigen bead assay (SAB)-detected pretransplant HLA antibodies (SAB-HLA-Ab) for kidney graft survival was evaluated retrospectively in 197 patients transplanted between 2002 and 2009 at the University Clinic ... ...

    Abstract Clinical relevance of ELISA- and single-antigen bead assay (SAB)-detected pretransplant HLA antibodies (SAB-HLA-Ab) for kidney graft survival was evaluated retrospectively in 197 patients transplanted between 2002 and 2009 at the University Clinic Frankfurt. Having adjusted for retransplantation and delayed graft function, a significantly increased risk for death-censored graft loss was found in patients with pretransplant SAB-HLA-Ab [HR: 4.46; 95% confidence interval (CI): 1.47-13.48; P = 0.008]. The risk for increased graft loss was also significant in patients with pretransplant SAB-HLA-Ab but without SAB-detected donor-specific Ab (SAB-DSA) (HR: 4.91; 95% CI of 1.43-16.991; P = 0.012). ELISA was not sufficient to identify pretransplant immunized patients with an increased risk for graft loss. In immunized patients, graft loss was predominantly present in patients who received transplants with a mismatch on the HLA-DR locus. In conclusion, even if our study is limited due to small sample size, the results show an increased risk for long-term graft loss in patients with pretransplant SAB-HLA, even in the absence of DSA. SAB-HLA-Ab-positive patients, being negative in ELISA or CDC assay, might profit from a well-HLA-DR-matched graft and intensified immunosuppression.
    MeSH term(s) Adult ; Aged ; Antibodies/blood ; Biopsy ; Delayed Graft Function/immunology ; Enzyme-Linked Immunosorbent Assay ; Female ; Graft Survival ; HLA Antigens/immunology ; Humans ; Immunization ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation ; Male ; Middle Aged ; Proteinuria/blood ; Renal Insufficiency/immunology ; Renal Insufficiency/surgery ; Retrospective Studies ; Risk Factors ; Time Factors ; Tissue Donors
    Chemical Substances Antibodies ; HLA Antigens ; Immunosuppressive Agents
    Language English
    Publishing date 2016-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/tri.12786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Long-term therapy of acute chronic liver failure to successful transplantation with an extracorporeal liver support system.

    Jung, O / Asbe-Vollkopf, A / Betz, C / Caspary, W / Geiger, H / Faust, D

    Zeitschrift fur Gastroenterologie

    2007  Volume 45, Issue 1, Page(s) 21–24

    Abstract: We report the case of a 38-year-old Caucasian male who was admitted because of end-stage liver failure due to primary sclerosing cholangitis. Because of the rapidly progressive severe hepatic encephalopathy and development of hepatorenal syndrome type I, ...

    Abstract We report the case of a 38-year-old Caucasian male who was admitted because of end-stage liver failure due to primary sclerosing cholangitis. Because of the rapidly progressive severe hepatic encephalopathy and development of hepatorenal syndrome type I, the patient was immediately upgraded to a high priority status on the liver transplantation waiting list (T2 status according to Eurotransplant criteria). Intermittent therapy with an extracorporeal liver support system (Prometheus) was initiated in order to bridge the time period until the expected transplantation date. Under therapy with the extracorporeal liver support system, total serum bilirubin decreased significantly from 33 to 15 mg/dL after 8 sessions. Simultaneously the encephalopathy resolved gradually within 3 weeks (10 sessions) from initially grade 3 to grade 1. Extracorporeal detoxification therapy was continued for 51 days (23 sessions) until the patient underwent his successful liver transplantation in good general clinical condition. Prometheus, a new liver support system, seemed to sufficiently replace hepatic detoxification on a long-term basis in this patient with end-stage liver failure in order to bridge the time period until liver transplantation.
    MeSH term(s) Adult ; Chronic Disease ; Combined Modality Therapy ; Extracorporeal Circulation/methods ; Humans ; Liver Failure, Acute/diagnosis ; Liver Failure, Acute/therapy ; Liver Transplantation/methods ; Male ; Preoperative Care/methods ; Treatment Outcome
    Language English
    Publishing date 2007-01
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/s-2006-927385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Transcatheter aortic valve implantation improves outcome compared to open-heart surgery in kidney transplant recipients requiring aortic valve replacement.

    Fox, Henrik / Büttner, Stefan / Hemmann, Katrin / Asbe-Vollkopf, Aida / Doss, Mirko / Beiras-Fernandez, Andres / Moritz, Anton / Zeiher, Andreas M / Scheuermann, Ernst / Geiger, Helmut / Fichtlscherer, Stephan / Hauser, Ingeborg A / Lehmann, Ralf

    Journal of cardiology

    2013  Volume 61, Issue 6, Page(s) 423–427

    Abstract: Background: Cardiovascular disease is the most frequent cause of mortality for kidney transplant recipients. Open heart surgery has particularly high mortality and morbidity. As an alternative to traditional aortic valve replacement (AVR) for patients ... ...

    Abstract Background: Cardiovascular disease is the most frequent cause of mortality for kidney transplant recipients. Open heart surgery has particularly high mortality and morbidity. As an alternative to traditional aortic valve replacement (AVR) for patients with high-grade aortic stenosis, transcatheter aortic valve implantation (TAVI) was developed as an innovative therapy for patients considered at high surgical risk.
    Methods: We considered all kidney transplant recipients as high-risk patients, which are candidates for TAVI. In 2010 and 2011, eight kidney transplant recipients with severe aortic stenosis underwent TAVI (6 transfemoral; 2 transapical; group I). The outcome of these patients was compared retrospectively to 18 kidney transplant recipients with aortic stenosis, who underwent conventional AVR (group II).
    Results: Both groups had similar baseline characteristics, including estimated perioperative risk (EuroSCORE group I vs. group II: 9.5±5.9 vs. 10.4±10.5; p=0.829). All TAVI procedures were performed successfully with excellent functional results. In the TAVI group (group I), all patients were alive at the 12-month follow-up with one cardiovascular event (stroke). In contrast, the surgical group experienced a 30-day-mortality of 11.1% (n=2) and a 1-year-mortality of 16.7% (n=3).
    Conclusions: Based on our center's experience, TAVI appears to be an effective and safe alternative to conventional surgery for AVR in patients with prior renal transplantation. Renal transplantation is not currently identified as a risk factor in our traditional scoring system, and may need to be considered independently when weighing alternatives for AVR.
    MeSH term(s) Aged ; Aortic Valve/surgery ; Aortic Valve Stenosis/etiology ; Aortic Valve Stenosis/surgery ; Cardiac Catheterization/methods ; Cardiac Surgical Procedures/methods ; Cardiac Surgical Procedures/mortality ; Female ; Follow-Up Studies ; Heart Valve Prosthesis Implantation/methods ; Humans ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Retrospective Studies ; Risk ; Treatment Outcome
    Language English
    Publishing date 2013-06
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 639364-0
    ISSN 1876-4738 ; 0386-2887 ; 0914-5087
    ISSN (online) 1876-4738
    ISSN 0386-2887 ; 0914-5087
    DOI 10.1016/j.jjcc.2013.01.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Coaxial probes for scanning near-field microscopy.

    Leinhos, T / Rudow, O / Stopka, M / Vollkopf, A / Oesterschulze, E

    Journal of microscopy

    2001  Volume 194, Issue Pt 2-3, Page(s) 349–352

    Abstract: This paper deals with the development of coaxial aperture tips integrated in a cantilever probe for combined scanning near-field infrared microscopy and scanning force microscopy. A fabrication process is introduced that allows the batch fabrication of ... ...

    Abstract This paper deals with the development of coaxial aperture tips integrated in a cantilever probe for combined scanning near-field infrared microscopy and scanning force microscopy. A fabrication process is introduced that allows the batch fabrication of hollow metal aperture tips integrated on a silicon cantilever. To achieve the coaxial tip arrangement a metal rod is deposited inside the hollow tip using the focused ion beam technique. Theoretical calculations with a finite integration code were performed to study the transmission characteristics of coaxial tips in comparison with conventional aperture probes. In addition, the influence of the geometrical design parameters of the coaxial probe on its optical behaviour is investigated.
    Language English
    Publishing date 2001-05-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 219263-9
    ISSN 1365-2818 ; 0022-2720
    ISSN (online) 1365-2818
    ISSN 0022-2720
    DOI 10.1046/j.1365-2818.1999.00538.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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