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  1. Article ; Online: Water-Ion Interaction Determines the Mobility of Ions in Highly Concentrated Aqueous Electrolytes.

    Kim, Jungyu / Koo, Bonhyeop / Khammari, Anahita / Park, Kwanghee / Lee, Hochun / Kwak, Kyungwon / Cho, Minhaeng

    ACS applied materials & interfaces

    2024  Volume 16, Issue 8, Page(s) 10033–10041

    Abstract: Solvation engineering plays a critical role in tailoring the performance of batteries, particularly through the use of highly concentrated electrolytes, which offer heterogeneous solvation structures of mobile ions with distinct electrochemical ... ...

    Abstract Solvation engineering plays a critical role in tailoring the performance of batteries, particularly through the use of highly concentrated electrolytes, which offer heterogeneous solvation structures of mobile ions with distinct electrochemical properties. In this study, we employed spectroscopic techniques and molecular dynamics simulations to investigate mixed-cation (Li
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c15609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Microwave-Mediated, Catalyst-Free Synthesis of 1,2,4-Triazolo[1,5-

    Lee, Kwanghee / Kim, Young-Ah / Jung, Chanhyun / Sim, Jaeuk / Rajasekar, Shanmugam / Kwak, Jae-Hwan / Viji, Mayavan / Jung, Jae-Kyung

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 4

    Abstract: A catalyst-free, additive-free, and eco-friendly method for synthesizing 1,2,4-triazolo[1,5- ...

    Abstract A catalyst-free, additive-free, and eco-friendly method for synthesizing 1,2,4-triazolo[1,5-
    Language English
    Publishing date 2024-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29040894
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: High-Throughput Synthesis of Nanogap-Rich Gold Nanoshells Using Dual-Channel Infusion System.

    Kim, Yoon-Hee / Cho, Hye-Seong / Yoo, Kwanghee / Ham, Kyeong-Min / Kang, Homan / Pham, Xuan-Hung / Jun, Bong-Hyun

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Gold nanoshells have been actively applied in industries beyond the research stage because of their unique optical properties. Although numerous methods have been reported for gold nanoshell synthesis, the labor-intensive and time-consuming production ... ...

    Abstract Gold nanoshells have been actively applied in industries beyond the research stage because of their unique optical properties. Although numerous methods have been reported for gold nanoshell synthesis, the labor-intensive and time-consuming production process is an issue that must be overcome to meet industrial demands. To resolve this, we report a high-throughput synthesis method for nanogap-rich gold nanoshells based on a core silica support (denoted as SiO
    MeSH term(s) Nanoshells ; Metal Nanoparticles ; Gold ; Silicon Dioxide
    Chemical Substances Gold (7440-57-5) ; Silicon Dioxide (7631-86-9)
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chemically Engineered Titanium Oxide Interconnecting Layer for Multijunction Polymer Solar Cells.

    Kim, Geunjin / Back, Hyungcheol / Kong, Jaemin / Naseer, Laiba / Jeong, Jiwon / Son, Jaehyoung / Lee, Jongjin / Kang, Sung-Oong / Lee, Kwanghee

    Polymers

    2024  Volume 16, Issue 5

    Abstract: We report chemically tunable n-type titanium oxides using ethanolamine as a nitrogen dopant source. As the amount of ethanolamine added to the titanium oxide precursor during synthesis increases, the Fermi level of the resulting titanium oxides ( ... ...

    Abstract We report chemically tunable n-type titanium oxides using ethanolamine as a nitrogen dopant source. As the amount of ethanolamine added to the titanium oxide precursor during synthesis increases, the Fermi level of the resulting titanium oxides (ethanolamine-incorporated titanium oxides) significantly changes from -4.9 eV to -4.3 eV, and their free charge carrier densities are enhanced by two orders of magnitudes, reaching up to 5 × 10
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16050595
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: High-level production and purification of bioactive recombinant human activin A in Chinese hamster ovary cells.

    Kim, Changin / Kim, Hyunjoo / Park, Jeong Soo / Park, Jiwon / Oh, Jeongmin / Yoon, Jaeseung / Baek, Kwanghee

    Preparative biochemistry & biotechnology

    2023  Volume 54, Issue 2, Page(s) 218–225

    Abstract: Activin A, a member of the TGF-β superfamily, is a homodimer of the inhibin ... ...

    Abstract Activin A, a member of the TGF-β superfamily, is a homodimer of the inhibin β
    MeSH term(s) Cricetinae ; Animals ; Humans ; Cricetulus ; CHO Cells ; Activins ; Bioreactors ; Recombinant Proteins/genetics
    Chemical Substances activin A ; Activins (104625-48-1) ; Recombinant Proteins
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1322522-4
    ISSN 1532-2297 ; 1082-6068
    ISSN (online) 1532-2297
    ISSN 1082-6068
    DOI 10.1080/10826068.2023.2214932
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Precise Filtration of Chronic Myeloid Leukemia Cells by an Ultrathin Microporous Membrane with Backflushing to Minimize Fouling.

    Lee, Jaehyuk / Hong, Jeongpyo / Lee, Jungwon / Lee, Changgyu / Kim, Tony / Jeong, Young / Kim, Kwanghee / Jung, Inhwa

    Membranes

    2023  Volume 13, Issue 8

    Abstract: A cell filtration platform that affords accurate size separation and minimizes fouling was developed. The platform features an ultra-thin porous membrane (UTM) filter, a pumping head filtration with backflush (PHF), and cell size measurement (CSM) ... ...

    Abstract A cell filtration platform that affords accurate size separation and minimizes fouling was developed. The platform features an ultra-thin porous membrane (UTM) filter, a pumping head filtration with backflush (PHF), and cell size measurement (CSM) software. The UTM chip is an ultrathin free-standing membrane with a large window area of 0.68 mm
    Language English
    Publishing date 2023-07-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes13080707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Tumor-infiltrating lymphocyte therapy: Clinical aspects and future developments in this breakthrough cancer treatment.

    Lee, Hyun / Kim, Kwanghee / Chung, Jiwon / Hossain, Mofazzal / Lee, Hee Jin

    BioEssays : news and reviews in molecular, cellular and developmental biology

    2023  Volume 45, Issue 7, Page(s) e2200204

    Abstract: Tumor-infiltrating lymphocyte (TIL) therapy is a promising approach for treating refractory or advanced solid cancers by using autologous TILs harvested from cancer tissues. Despite the heterogeneity of cancer, TIL therapy can potentially produce a ... ...

    Abstract Tumor-infiltrating lymphocyte (TIL) therapy is a promising approach for treating refractory or advanced solid cancers by using autologous TILs harvested from cancer tissues. Despite the heterogeneity of cancer, TIL therapy can potentially produce a positive therapeutic response, including complete remission. After decades of research on lymphocyte functions, culture/expansion methods, therapeutic protocols, and multiple clinical trials, TIL therapy has finally reached a stage where it can be formally approved for clinical use. TIL therapy is expected to hold a unique position among anti-cancer therapeutic options as a standard intervention. To successfully introduce TIL therapy into clinical settings, there is a need to expand therapeutic indications and set up the best protocols for cancer tissue sampling and manufacturing, and related clinical trials. Moreover, studies on next-generation TIL therapy have already begun, and post-approval real-world data will promote and support further research.
    MeSH term(s) Humans ; Lymphocytes, Tumor-Infiltrating ; Immunotherapy, Adoptive/methods ; Neoplasms/therapy
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202200204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: CCR10-mediated Enhancement of T Cell Trafficking for Improved Tumor Immunotherapy.

    Hong, Jong Moo / Jeong, Byung-Kwan / Han, Doyeon / Kim, Kwanghee / Lee, In Won / Hong, Chorong / Lee, Gunhee / Gong, Gyungyub / Lee, Hee Jin

    Anticancer research

    2024  Volume 44, Issue 2, Page(s) 521–532

    Abstract: Background/aim: The effectiveness of adoptive T cell therapy for solid tumors remains suboptimal, partly attributed to insufficient T cell infiltration into the tumor site. A promising strategy involves directing T cells towards the tumor utilizing ... ...

    Abstract Background/aim: The effectiveness of adoptive T cell therapy for solid tumors remains suboptimal, partly attributed to insufficient T cell infiltration into the tumor site. A promising strategy involves directing T cells towards the tumor utilizing tumor-specific chemokine receptors.
    Materials and methods: We analyzed chemokine receptor expression in activated T cells and chemokine expression in breast and lung cancer using The Cancer Genome Atlas (TCGA) data. Subsequently, we generated 1G4 T cell receptor-engineered T (TCR-T) cells with CCR10 and performed in vitro and in vivo efficacy tests.
    Results: CCR10 exhibited insufficient expression in various human T cells. Analysis of TCGA RNA sequencing data revealed elevated expression of the chemokine CCL28, the corresponding chemokine for CCR10, in breast and lung cancer. Consequently, we generated CCR10-1G4 TCR-T cells. CCR10-1G4 dual expressing TCR-T cells exhibited comparable cellular cytotoxicity but increased mobility compared to 1G4 TCR-T cells in vitro. Furthermore, injecting CCR10-1G4 dual expressing TCR-T cells into a xenograft tumor model demonstrated enhanced in vivo trafficking and a greater reduction of tumor burden.
    Conclusion: This study highlights the potential of CCR10 for developing efficient adoptive T-cell treatments targeting solid tumors.
    MeSH term(s) Humans ; T-Lymphocytes/metabolism ; Chemokines/metabolism ; Receptors, Chemokine ; Immunotherapy ; Lung Neoplasms/therapy ; Receptors, Antigen, T-Cell/genetics ; Receptors, CCR10/genetics ; Receptors, CCR10/metabolism
    Chemical Substances Chemokines ; Receptors, Chemokine ; Receptors, Antigen, T-Cell ; CCR10 protein, human ; Receptors, CCR10
    Language English
    Publishing date 2024-02-01
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Synthesis and photophysical properties of

    Trinh, Cuc Kim / Nassar, Gamal M / Abdo, Nabiha I / Jung, Suhyun / Kim, Wonbin / Lee, Kwanghee / Lee, Jae-Suk

    RSC advances

    2022  Volume 12, Issue 28, Page(s) 17682–17688

    Abstract: Two kinds of donor-acceptor π-conjugated copolymer based on poly{[ ...

    Abstract Two kinds of donor-acceptor π-conjugated copolymer based on poly{[
    Language English
    Publishing date 2022-06-15
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra02608b
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  10. Article ; Online: Efficient and Stable Perovskite Solar Cells with a High Open-Circuit Voltage Over 1.2 V Achieved by a Dual-Side Passivation Layer.

    Kim, Ju-Hyeon / Kim, Yong Ryun / Kim, Juae / Oh, Chang-Mok / Hwang, In-Wook / Kim, Jehan / Zeiske, Stefan / Ki, Taeyoon / Kwon, Sooncheol / Kim, Heejoo / Armin, Ardalan / Suh, Hongsuk / Lee, Kwanghee

    Advanced materials (Deerfield Beach, Fla.)

    2023  Volume 35, Issue 14, Page(s) e2300754

    Language English
    Publishing date 2023-04-06
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202300754
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