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Article ; Online: A terpyridyl-imidazole based europium tris-(β-diketonate) complex as an efficient molecular luminescent thermometer and single component white light emitter

Ahmed, Toushique / Chakraborty, Amit / Maity, Sanchari / Baitalik, Sujoy

Dalton transactions (Cambridge, England : 2003)

2024 Volume 53, Issue 7, Page(s) 3065–3074

Abstract: The thermosensing and thermochromic behavior of one of our recently reported terpyridyl-imidazole based ternary europium tris-(β-diketonate) complexes of the composition [Eu(tta) ...

Abstract	The thermosensing and thermochromic behavior of one of our recently reported terpyridyl-imidazole based ternary europium tris-(β-diketonate) complexes of the composition [Eu(tta)
Language	English
Publishing date	2024-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d3dt03837h
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity.

Maity, Amit / Koumenis, Constantinos

Clinical cancer research : an official journal of the American Association for Cancer Research

2022 Volume 28, Issue 17, Page(s) 3636–3638

Abstract: A recent study reported results from a clinical trial in cats and from experiments in mini-pigs in which a single dose of radiotherapy was delivered at ultrahigh dose rates (FLASH). There was acceptable acute toxicity; however, some animals suffered ... ...

Abstract	A recent study reported results from a clinical trial in cats and from experiments in mini-pigs in which a single dose of radiotherapy was delivered at ultrahigh dose rates (FLASH). There was acceptable acute toxicity; however, some animals suffered severe late toxicity, raising caution in the design of future trials. See related article by Rohrer Bley et al., p. 3814.
MeSH term(s)	Animals ; Carcinoma, Squamous Cell ; Cats ; Radiation Oncology ; Radiotherapy Dosage ; Swine ; Swine, Miniature
Language	English
Publishing date	2022-06-22
Publishing country	United States
Document type	Editorial ; Research Support, N.I.H., Extramural ; Comment
ZDB-ID	1225457-5
ISSN	1557-3265 ; 1078-0432
ISSN (online)	1557-3265
ISSN	1078-0432
DOI	10.1158/1078-0432.CCR-22-1255
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Article ; Online: VEGF Secretion Drives Bone Formation in Classical MAP2K1+ Melorheostosis.

Allbritton-King, Jules D / Maity, Jyotirindra / Patel, Amit / Colbert, Robert A / Navid, Fatemeh / Bhattacharyya, Timothy

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

2023 Volume 38, Issue 12, Page(s) 1834–1845

Abstract: Patients with classical melorheostosis exhibit exuberant bone overgrowth in the appendicular skeleton, resulting in pain and deformity with no known treatment. Most patients have somatic, mosaic mutations in MAP2K1 (encoding the MEK1 protein) in ... ...

Abstract	Patients with classical melorheostosis exhibit exuberant bone overgrowth in the appendicular skeleton, resulting in pain and deformity with no known treatment. Most patients have somatic, mosaic mutations in MAP2K1 (encoding the MEK1 protein) in osteoblasts and overlying skin. As with most rare bone diseases, lack of affected tissue has limited the opportunity to understand how the mutation results in excess bone formation. The aim of this study was to create a cellular model to study melorheostosis. We obtained patient skin cells bearing the MAP2K1 mutation (affected cells), and along with isogenic control normal fibroblasts reprogrammed them using the Sendai virus method into induced pluripotent stem cells (iPSCs). Pluripotency was validated by marker staining and embryoid body formation. iPSCs were then differentiated to mesenchymal stem cells (iMSCs) and validated by flow cytometry. We confirmed retention of the MAP2K1 mutation in iMSCs with polymerase chain reaction (PCR) and confirmed elevated MEK1 activity by immunofluorescence staining. Mutation-bearing iMSCs showed significantly elevated vascular endothelial growth factor (VEGF) secretion, proliferation and collagen I and IV secretion. iMSCs were then differentiated into osteoblasts, which showed increased mineralization at 21 days and increased VEGF secretion at 14 and 21 days of differentiation. Administration of VEGF to unaffected iMSCs during osteogenic differentiation was sufficient to increase mineralization. Blockade of VEGF by bevacizumab reduced mineralization in iMSC-derived affected osteoblasts and in affected primary patient-derived osteoblasts. These data indicate that patient-derived induced pluripotent stem cells recreate the elevated MEK1 activity, increased mineralization, and increased proliferation seen in melorheostosis patients. The increased bone formation is driven, in part, by abundant VEGF secretion. Modifying the activity of VEGF (a known stimulator of osteoblastogenesis) represents a promising treatment pathway to explore. iPSCs may have wide applications to other rare bone diseases. © 2023 American Society for Bone and Mineral Research (ASBMR).
MeSH term(s)	Humans ; Bone and Bones/metabolism ; Cell Differentiation ; MAP Kinase Kinase 1/genetics ; Melorheostosis/genetics ; Osteogenesis/genetics ; Vascular Endothelial Growth Factor A
Chemical Substances	MAP Kinase Kinase 1 (EC 2.7.12.2) ; MAP2K1 protein, human (EC 2.7.12.2) ; Vascular Endothelial Growth Factor A ; VEGFA protein, human
Language	English
Publishing date	2023-10-24
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Intramural
ZDB-ID	632783-7
ISSN	1523-4681 ; 0884-0431
ISSN (online)	1523-4681
ISSN	0884-0431
DOI	10.1002/jbmr.4915
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Zs.A 2142: Show issues

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Article ; Online: N-Heterocyclic imino-catalyzed 1,4-regioselective azide-alkyne cycloaddition (AAC): a metal-free approach.

Revathi, Shanmugam / Shinde, Aditya L / Rajashekhar, Mulimani K / Mandal, Debasish / Maity, Amit Ranjan / Garai, Somenath / Ghatak, Tapas

Chemical communications (Cambridge, England)

2023 Volume 59, Issue 85, Page(s) 12699–12702

Abstract: An unprecedented synthetic approach has been devised to efficiently synthesize regioselective 1,4-disubstituted 1,2,3-triazoles. This technique relies on the use of innovative metal-free highly basic N-heterocyclic imino catalysts. The experimental ... ...

Abstract	An unprecedented synthetic approach has been devised to efficiently synthesize regioselective 1,4-disubstituted 1,2,3-triazoles. This technique relies on the use of innovative metal-free highly basic N-heterocyclic imino catalysts. The experimental observations have been supported further by TD-DFT computational studies.
Language	English
Publishing date	2023-10-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d3cc04065h
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Article ; Online: Exploring the potential of broadband Tamm plasmon resonance for enhanced photodetection.

Poddar, Krishanu / Sinha, Rajarshi / Jana, Babita / Chatterjee, Supratim / Mukherjee, Rupam / Maity, Amit Ranjan / Kumar, Samir / Maji, Partha Sona

Applied optics

2023 Volume 62, Issue 30, Page(s) 8190–8196

Abstract: Tamm plasmon polaritons (TPPs) have emerged as a promising platform for photodetector applications due to their strong light-matter interaction and potential for efficient light absorption. In this work, a design for a broadband photodetector (PD) based ... ...

Abstract	Tamm plasmon polaritons (TPPs) have emerged as a promising platform for photodetector applications due to their strong light-matter interaction and potential for efficient light absorption. In this work, a design for a broadband photodetector (PD) based on the optical Tamm plasmon (OTS) state generated in a periodic metal-semiconductor-distributed Bragg reflector (DBR) geometry is proposed. The transfer matrix method (TMM) was used to study the propagation of electromagnetic waves through the proposed structure. By exciting the structure with incident light and analyzing the electric field profile within the multilayer structure at the resonant wavelength, we observe a distinctive electric field distribution that indicates the presence of Tamm plasmon modes. A comparative study was conducted to investigate the optical properties of a photodetector in the near-infrared (NIR) range by varying parameters such as thickness. By optimizing the thickness, we successfully achieved a broadband photoresponse in the photodetector, with a maximum responsivity of 21.8 mA/W at a wavelength of 1354 nm, which falls within the photonic bandgap region. FWHM was found to be 590 nm for the responsivity spectrum. The geometry also presents maximum absorption with FWHM calculated to be about 871.5 nm. The proposed geometry offers a broadband photoresponse, which is advantageous for the advancement of Tamm-based detector technologies. The ability to detect light over a wide operation range makes this mechanism highly beneficial for various applications.
Language	English
Publishing date	2023-12-01
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.501588
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Article ; Online: Geo-environmental factors and the effectiveness of mulberry leaf extract in managing malaria.

Pradhan, Sayantan / Hore, Samrat / Roy, Stabak / Manna, Simi / Dam, Paulami / Mondal, Rittick / Ghati, Amit / Biswas, Trishanjan / Shaw, Subhajit / Sharma, Supriya / Singh, Waikhom Somraj / Maji, Suman Kumar / Roy, Sankarsan / Basu, Aparajita / Pandey, Kailash C / Samanta, Soumadri / Vashisht, Kapil / Dolai, Tuphan Kanti / Kundu, Pratip Kumar /

Mitra, Saptarshi / Biswas, Debasish / Sadat, Abdul / Shokriyan, Masuma / Maity, Amit Bikram / Mandal, Amit Kumar / İnce, İkbal Agah

Scientific reports

2023 Volume 13, Issue 1, Page(s) 14808

Abstract: Malaria prevalence has become medically important and a socioeconomic impediment for the endemic regions, including Purulia, West Bengal. Geo-environmental variables, humidity, altitude, and land use patterns are responsible for malaria. For surveillance ...

Abstract	Malaria prevalence has become medically important and a socioeconomic impediment for the endemic regions, including Purulia, West Bengal. Geo-environmental variables, humidity, altitude, and land use patterns are responsible for malaria. For surveillance of the endemic nature of Purulia's blocks, statistical and spatiotemporal factors analysis have been done here. Also, a novel approach for the Pf malaria treatment using methanolic leaf extract of Morus alba S1 has significantly reduced the parasite load. The EC
MeSH term(s)	Morus ; Malaria/drug therapy ; Chloroquine ; Malaria, Falciparum ; Methanol ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
Chemical Substances	Chloroquine (886U3H6UFF) ; Methanol (Y4S76JWI15) ; Plant Extracts
Language	English
Publishing date	2023-09-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-41668-3
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Article ; Online: Efficient Synergistic Antibacterial Activity of α-MSH Using Chitosan-Based Versatile Nanoconjugates.

Barman, Sourav / Chakraborty, Asmita / Saha, Sujata / Sikder, Kunal / Maitra Roy, Sayoni / Modi, Barkha / Bahadur, Sabarnee / Khan, Ali Hossain / Manna, Dipak / Bag, Pousali / Sarkar, Ankan Kumar / Bhattacharya, Rishi / Basu, Arnab / Maity, Amit Ranjan

ACS omega

2023 Volume 8, Issue 14, Page(s) 12865–12877

Abstract: The application of antimicrobial peptides has emerged as an alternative therapeutic tool to encounter against multidrug resistance of different pathogenic organisms. α-Melanocyte stimulating hormone (α-MSH), an endogenous neuropeptide, is found to be ... ...

Abstract	The application of antimicrobial peptides has emerged as an alternative therapeutic tool to encounter against multidrug resistance of different pathogenic organisms. α-Melanocyte stimulating hormone (α-MSH), an endogenous neuropeptide, is found to be efficient in eradicating infection of various kinds of
Language	English
Publishing date	2023-03-30
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c08209
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Article: Evaluation of the cumulative Cherenkov converted dose on TSET patients with multiple Cherenkov cameras.

Zhu, Yifeng / Alexander, Daniel A / Miao, Tianshun / Maity, Amit / Plastaras, John P / Paydar, Ima / LaRiviere, Michael / Pogue, Brian W / Zhu, Timothy C

Proceedings of SPIE--the International Society for Optical Engineering

2023 Volume 12359

Abstract: Cherenkov images can be used for the quality assurance of dose homogeneity in total skin electron therapy (TSET). For the dose mapping purpose, this study reconstructed the patient model from 3D scans using registration algorithms and computer animation ... ...

Abstract	Cherenkov images can be used for the quality assurance of dose homogeneity in total skin electron therapy (TSET). For the dose mapping purpose, this study reconstructed the patient model from 3D scans using registration algorithms and computer animation techniques. The Cherenkov light emission of the patient's surface was extracted from multi-view Cherenkov images, converted into dose distribution, and projected onto the patient's 3D model, allowing for dose cumulation and evaluation. The projected result from multiple Cherenkov cameras provides additional information about Cherenkov emission on the sides of the patients, which improves the agreement between the Cherenkov converted dose and the OSLD measurements.
Language	English
Publishing date	2023-03-14
Publishing country	United States
Document type	Journal Article
ISSN	0277-786X
ISSN	0277-786X
DOI	10.1117/12.2651177
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Article ; Online: Critical phase boundaries of static and periodically kicked long-range Kitaev chain.

Bhattacharya, Utso / Maity, Somnath / Dutta, Amit / Sen, Diptiman

Journal of physics. Condensed matter : an Institute of Physics journal

2019 Volume 31, Issue 17, Page(s) 174003

Abstract: We study the static and dynamical properties of a long-range Kitaev chain, i.e. a p -wave superconducting chain in which the superconducting pairing decays algebraically as [Formula: see text], where l is the distance between the two sites and [Formula: ... ...

Abstract	We study the static and dynamical properties of a long-range Kitaev chain, i.e. a p -wave superconducting chain in which the superconducting pairing decays algebraically as [Formula: see text], where l is the distance between the two sites and [Formula: see text] is a positive constant. Considering very large system sizes, we show that when [Formula: see text], the system is topologically equivalent to the short-range Kitaev chain with massless Majorana modes at the ends of the system; on the contrary, for [Formula: see text], there exist symmetry protected massive Dirac end modes. We further study the dynamical phase boundary of the model when periodic [Formula: see text]-function kicks are applied to the chemical potential; we specially focus on the case [Formula: see text] and analyze the corresponding Floquet quasienergies. Interestingly, we find that new topologically protected massless end modes are generated at the quasienergy [Formula: see text] (where T is the time period of driving) in addition to the end modes at zero energies which exist in the static case. By varying the frequency of kicking, we can produce topological phase transitions between different dynamical phases. Finally, we propose some bulk topological invariants which correctly predict the number of massless end modes at quasienergies equal to 0 and [Formula: see text] for a periodically kicked system with [Formula: see text].
Language	English
Publishing date	2019-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	1472968-4
ISSN	1361-648X ; 0953-8984
ISSN (online)	1361-648X
ISSN	0953-8984
DOI	10.1088/1361-648X/ab03b9
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Article ; Online: Plasma D-Dimer Levels are Elevated in Radiation Oncology Patients.

Louneva, Natalia / Maity, Amit / Kennedy, Ann R

Radiation research

2019 Volume 193, Issue 1, Page(s) 46–53

Abstract: D-dimer plasma levels were evaluated to determine whether they are altered by radiation. D-dimer levels were measured in radiation oncology patients, who were diagnosed with prostate, breast or lung cancer, or leukemia, as well as in healthy subjects ... ...

Abstract	D-dimer plasma levels were evaluated to determine whether they are altered by radiation. D-dimer levels were measured in radiation oncology patients, who were diagnosed with prostate, breast or lung cancer, or leukemia, as well as in healthy subjects serving as controls. Blood samples from radiotherapy patients were taken at three different time points: pre-, on- and post-radiotherapy. For the patients, considered together, differences between the D-dimer levels at these three time points compared to controls were statistically significant. Compared to the pre-radiotherapy measurements, radiation exposure was associated with a significant increase in the D-dimer levels at the on- and post-radiotherapy time points. At the post-radiotherapy time point, D-dimer levels in the patients were not significantly reduced compared to the on-radiotherapy levels, indicating that the risk for developing disseminated intravascular coagulation (DIC) may be increased in some radiation oncology patients. Of particular concern are the post-radiotherapy results observed for the D-dimer levels in the leukemia patients, in which the average fold increase in the D-dimer levels was 5.43 (compared to the pre-radiotherapy levels). These results suggest that leukemia patients might benefit from frequent assessment of their D-dimer levels after their total-body irradiation-conditioning regimen to detect early signs of DIC development. It is hoped that the results described here will lead to heightened awareness in the radiation oncology community that the risk of DIC development is greatly increased in some of these patients.
MeSH term(s)	Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Neoplasms/blood ; Neoplasms/radiotherapy ; Radiation Oncology
Chemical Substances	Fibrin Fibrinogen Degradation Products ; fibrin fragment D
Language	English
Publishing date	2019-11-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	80322-4
ISSN	1938-5404 ; 0033-7587
ISSN (online)	1938-5404
ISSN	0033-7587
DOI	10.1667/RR15429.1
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