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  1. Article ; Online: Retraction: Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites.

    Wang, Maorong / Yao, Ping / Gao, Minpeng / Jin, Jian / Yu, Yerong

    RSC advances

    2024  Volume 14, Issue 3, Page(s) 1625

    Abstract: This retracts the article DOI: 10.1039/C9RA10593J.]. ...

    Abstract [This retracts the article DOI: 10.1039/C9RA10593J.].
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Retraction of Publication
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra90124f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Expression of Concern: Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites.

    Wang, Maorong / Yao, Ping / Gao, Minpeng / Jin, Jian / Yu, Yerong

    RSC advances

    2022  Volume 12, Issue 51, Page(s) 33348

    Abstract: ... prolonged anti-diabetic effects through targeting receptor binding sites' by Maorong Wang ...

    Abstract Expression of Concern for 'Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites' by Maorong Wang
    Language English
    Publishing date 2022-11-22
    Publishing country England
    Document type Expression of Concern
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra90118h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: THERAPEUTIC EFFECTS OF COMBINATION REGIMENS INCLUDING METHIMAZOLE ON GRAVES HYPERTHYROIDISM: A NETWORK META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.

    Wang, Maorong / Yu, Yerong

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

    2020  Volume 26, Issue 6, Page(s) 675–687

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Antithyroid Agents ; Humans ; Hyperthyroidism ; Methimazole ; Network Meta-Analysis ; Randomized Controlled Trials as Topic ; Thyroxine ; Triiodothyronine
    Chemical Substances Antithyroid Agents ; Triiodothyronine (06LU7C9H1V) ; Methimazole (554Z48XN5E) ; Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2020-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1473503-9
    ISSN 1530-891X
    ISSN 1530-891X
    DOI 10.4158/EP-2019-0555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5034: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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    Zs.MO 508: Show issues

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  4. Article ; Online: The GBM rapid product and the improvement from undifferenced ambiguity resolution

    DENG Zhiguo / WANG Jungang / GE Maorong

    Acta Geodaetica et Cartographica Sinica, Vol 51, Iss 4, Pp 544-

    2022  Volume 555

    Abstract: Global navigation satellite systems (GNSS) plays a critical role for providing real-time position-ing and navigation services, and the precise satellite orbit and clock products are essential for the high-precision GNSS applications. The international ... ...

    Abstract Global navigation satellite systems (GNSS) plays a critical role for providing real-time position-ing and navigation services, and the precise satellite orbit and clock products are essential for the high-precision GNSS applications. The international GNSS service (IGS) and its analysis centers (ACs) have been working on the study on precise GNSS data processing and provision of the precise products. The German research center for geosciences (GFZ), as one of the ACs, also provides the multi-GNSS rapid product: the GBM product. We introduce the GBM data processing strategy, analyze the precision of GBM multi-GNSS orbits from 2015 to 2021, and present the impact of applying the undifferenced ambiguity resolution on satellite orbits. The GPS orbits of GBM products agree with the IGS final orbits at the level of 11~13 mm in the three directions, and the GPS orbit 6 hour prediction precision is around 6 cm. The 6 hour prediction precision of GLONASS is around 12 cm, slightly worse than that of Galileo, which holds an average value of 10 cm in the same period but shows a significant improvement to around 5 cm after the end of 2016. The prediction precision of BDS medium earth orbit (MEO) satellites are around 10 cm, and that of the BDS geostationary earth orbit, (GEO) satellites and QZSS satellites are at the level of 1 to 3 meter. The satellite laser ranging (SLR) residuals show that the orbit precision of Galileo, GLONASS, and BDS3-MEO are 23, 41, and 47 mm, respectively. Moreover, comparing the double-differenced ambiguity resolution, adopting the undifferenced ambiguity resolution improves the 6 hour orbit prediction precision by 9%~15%, 15%~18%, 11%~13%, 6%~17% and 14%~25% for the GPS, GLONASS, Galileo, BDS-2 and BDS-3 MEO satellites, respectively.
    Keywords gnss ; precise orbit determination ; ambiguity fixing ; Mathematical geography. Cartography ; GA1-1776
    Language Chinese
    Publishing date 2022-04-01T00:00:00Z
    Publisher Surveying and Mapping Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Improving the Orbits of the BDS-2 IGSO and MEO Satellites with Compensating Thermal Radiation Pressure Parameters

    Chen Wang / Jing Guo / Qile Zhao / Maorong Ge

    Remote Sensing, Vol 14, Iss 641, p

    2022  Volume 641

    Abstract: The orbit accuracy of the navigation satellites relies on the accurate knowledge of the forces on the spacecraft, in particular the non-conservative perturbations. This study focuses on the Inclined Geosynchronous Orbit (IGSO) and Medium Earth Orbit (MEO) ...

    Abstract The orbit accuracy of the navigation satellites relies on the accurate knowledge of the forces on the spacecraft, in particular the non-conservative perturbations. This study focuses on the Inclined Geosynchronous Orbit (IGSO) and Medium Earth Orbit (MEO) satellites of the regional Chinese BeiDou Navigation Satellite System (BDS-2), for which apparent deficiencies of non-conservative models are identified and evidenced in the Satellite Laser Ranging (SLR) residuals. The orbit errors derived from the empirical 5-parameter Extended CODE Orbit Model (ECOM) as well as a semi-analytical adjustable box-wing model show prominent dependency on the Sun elongation angle, even in the yaw-steering attitude mode. Hence, a periodic acceleration in the normal direction of the +X surface, presumably generated by the mismodeled thermal radiation pressure, is introduced. The SLR validations reveal that the Sun elongation angle-dependent systematic errors were significantly reduced, and the orbit accuracy was improved by 10–30% to approximately 4.5 cm and 3.0 cm for the BDS-2 IGSO and MEO satellites, respectively.
    Keywords BDS-2 ; precise orbit determination ; thermal radiation pressure ; solar radiation pressure ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Fe-catalyzed reduction of aldimines with HBpin

    Lei, Siyu / Pan, Tao / Wang, Maorong / Zhang, Yuexia

    Tetrahedron letters. 2022 June 10,

    2022  

    Abstract: We develop an efficient and workable method for the reduction of imines via hydroboration with HBpin. The low cost and non-toxic Fe exhibits high catalytic activity to this hydroboration. A large range of aldimines comprising diverse aryl groups, alkyl ... ...

    Abstract We develop an efficient and workable method for the reduction of imines via hydroboration with HBpin. The low cost and non-toxic Fe exhibits high catalytic activity to this hydroboration. A large range of aldimines comprising diverse aryl groups, alkyl groups and heterocycles proceed the hydroboration well to yield secondary amines in good to excellent yields. Kinetic mechanistic studies indicate the importance of Fe in transformation of HBpin into an active species. The preparation of several commercially available pharmaceuticals by means of this strategy highlights its potential application in medicinal chemistry.
    Keywords aldimines ; catalytic activity ; drugs ; heterocyclic compounds
    Language English
    Dates of publication 2022-0610
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 204287-3
    ISSN 1873-3581 ; 0040-4039
    ISSN (online) 1873-3581
    ISSN 0040-4039
    DOI 10.1016/j.tetlet.2022.153949
    Database NAL-Catalogue (AGRICOLA)

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    Zs.A 2837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online: MetaMixer

    Wang, Maorong / Xiao, Ling / Yamasaki, Toshihiko

    A Regularization Strategy for Online Knowledge Distillation

    2023  

    Abstract: Online knowledge distillation (KD) has received increasing attention in recent years. However, while most existing online KD methods focus on developing complicated model structures and training strategies to improve the distillation of high-level ... ...

    Abstract Online knowledge distillation (KD) has received increasing attention in recent years. However, while most existing online KD methods focus on developing complicated model structures and training strategies to improve the distillation of high-level knowledge like probability distribution, the effects of the multi-level knowledge in the online KD are greatly overlooked, especially the low-level knowledge. Thus, to provide a novel viewpoint to online KD, we propose MetaMixer, a regularization strategy that can strengthen the distillation by combining the low-level knowledge that impacts the localization capability of the networks, and high-level knowledge that focuses on the whole image. Experiments under different conditions show that MetaMixer can achieve significant performance gains over state-of-the-art methods.

    Comment: 10 pages, 4 figures
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Publishing date 2023-03-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Improving the Orbits of the BDS-2 IGSO and MEO Satellites with Compensating Thermal Radiation Pressure Parameters

    Wang, Chen / Guo, Jing / Zhao, Qile / Ge, Maorong

    Remote Sensing. 2022 Jan. 28, v. 14, no. 3

    2022  

    Abstract: The orbit accuracy of the navigation satellites relies on the accurate knowledge of the forces on the spacecraft, in particular the non-conservative perturbations. This study focuses on the Inclined Geosynchronous Orbit (IGSO) and Medium Earth Orbit (MEO) ...

    Abstract The orbit accuracy of the navigation satellites relies on the accurate knowledge of the forces on the spacecraft, in particular the non-conservative perturbations. This study focuses on the Inclined Geosynchronous Orbit (IGSO) and Medium Earth Orbit (MEO) satellites of the regional Chinese BeiDou Navigation Satellite System (BDS-2), for which apparent deficiencies of non-conservative models are identified and evidenced in the Satellite Laser Ranging (SLR) residuals. The orbit errors derived from the empirical 5-parameter Extended CODE Orbit Model (ECOM) as well as a semi-analytical adjustable box-wing model show prominent dependency on the Sun elongation angle, even in the yaw-steering attitude mode. Hence, a periodic acceleration in the normal direction of the +X surface, presumably generated by the mismodeled thermal radiation pressure, is introduced. The SLR validations reveal that the Sun elongation angle-dependent systematic errors were significantly reduced, and the orbit accuracy was improved by 10–30% to approximately 4.5 cm and 3.0 cm for the BDS-2 IGSO and MEO satellites, respectively.
    Keywords models ; satellites ; spacecraft ; thermal radiation
    Language English
    Dates of publication 2022-0128
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2513863-7
    ISSN 2072-4292
    ISSN 2072-4292
    DOI 10.3390/rs14030641
    Database NAL-Catalogue (AGRICOLA)

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  9. Book ; Online: Improving Plasticity in Online Continual Learning via Collaborative Learning

    Wang, Maorong / Michel, Nicolas / Xiao, Ling / Yamasaki, Toshihiko

    2023  

    Abstract: Online Continual Learning (CL) solves the problem of learning the ever-emerging new classification tasks from a continuous data stream. Unlike its offline counterpart, in online CL, the training data can only be seen once. Most existing online CL ... ...

    Abstract Online Continual Learning (CL) solves the problem of learning the ever-emerging new classification tasks from a continuous data stream. Unlike its offline counterpart, in online CL, the training data can only be seen once. Most existing online CL research regards catastrophic forgetting (i.e., model stability) as almost the only challenge. In this paper, we argue that the model's capability to acquire new knowledge (i.e., model plasticity) is another challenge in online CL. While replay-based strategies have been shown to be effective in alleviating catastrophic forgetting, there is a notable gap in research attention toward improving model plasticity. To this end, we propose Collaborative Continual Learning (CCL), a collaborative learning based strategy to improve the model's capability in acquiring new concepts. Additionally, we introduce Distillation Chain (DC), a novel collaborative learning scheme to boost the training of the models. We adapted CCL-DC to existing representative online CL works. Extensive experiments demonstrate that even if the learners are well-trained with state-of-the-art online CL methods, our strategy can still improve model plasticity dramatically, and thereby improve the overall performance by a large margin.

    Comment: Under review
    Keywords Computer Science - Machine Learning
    Subject code 004
    Publishing date 2023-12-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Gestodene causes masculinization of the western mosquitofish (Gambusia affinis): Insights from ovary metabolomics.

    Li, Yelin / Tan, Zhiqing / Zuo, Peiyu / Li, Maorong / Hou, Liping / Wang, Xiaolan

    The Science of the total environment

    2023  Volume 912, Page(s) 168693

    Abstract: Gestodene (GES) is a common synthetic progesterone frequently detected in aquatic environments. Chronic exposure to GES can cause masculinization of a variety of fish; however, whether metabolism is closely related to the masculinization has yet to be ... ...

    Abstract Gestodene (GES) is a common synthetic progesterone frequently detected in aquatic environments. Chronic exposure to GES can cause masculinization of a variety of fish; however, whether metabolism is closely related to the masculinization has yet to be explored. Hence, the ovary metabolome of adult female western mosquitofish (Gambusia affinis) after exposing to GES (0.0, 5.0, 50.0, and 500.0 ng/L) for 40 days was analyzed by using high-performance liquid chromatography ionization with quadrupole time-of-flight tandem mass spectrometry (HPLC-QTOF-MS). The results showed that GES increased the levels of cysteine, taurine, ophthalmic acid and cAMP while decreased methionine, these metabolites changes may owing to the oxidative stress of the ovaries; while taurcholic acid and uric acid were decreased along with induced oocyte apopotosis. Steroids hormone metabolism was also significantly affected, with progesterone and cortisol being the most affected. Enzyme-linked immunoassay results showed that estradiol levels were decreased while testosterone levels were increased with GES exposure. In addition, correlation analysis showed that the differential metabolites of some amino acids (e.g. leucine) were strongly correlated with the levels of steroids hormones secreted by the pituitary gland. The results of this study suggest that GES affects ovarian metabolism via the hypothalamus-pituitary-gonad and hypothalamic-pituitary-adrenal axes, impair antioxidant capacity, induce apoptosis in the ovary of G. affinis, and finally caused masculinization.
    MeSH term(s) Animals ; Female ; Ovary ; Progesterone/metabolism ; Steroids/metabolism ; Cyprinodontiformes/metabolism ; Norpregnenes
    Chemical Substances Progesterone (4G7DS2Q64Y) ; Gestodene (1664P6E6MI) ; Steroids ; Norpregnenes
    Language English
    Publishing date 2023-11-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.168693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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