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Book ; Online: The Impact of COVID-19 on Financial Markets and the Real Economy

Gherghina, Ştefan Cristian / Gherghina, Ştefan Cristian

2023

Keywords	Economics, finance, business & management ; COVID-19 ; pandemic ; tourism ; impact ; Vietnam ; entry mode ; mergers and acquisitions (M&As) ; sustainable development goal (SDG) index ; generalized linear model (GLM) ; economic groups ; family firms ; economic concentration ; economic power ; Latin America ; Ecuador ; coronavirus ; US economy ; multiplier effects ; tourism sector ; COVID-19 pandemic ; stock market ; stock index ; market volatility ; impulse response functions ; GARCH (1,1) model ; banking sector ; COVID-19 outbreak ; corporate insolvency ; simulation ; loan restructuring policy ; system dynamics ; early warning early action ; urban ; rural ; informal labor ; credit access ; quality of life ; Canada ; labour market ; industrial sectors ; financial time series forecasting ; stock markets ; forecasting methods ; technical analysis ; financial technology ; TAM model ; TRA model ; trade ; GDP ; economy ; labor market ; informational spread of coronavirus ; information environment ; monetary policy ; the COVID-19 pandemic ; policy responses ; DSGE models ; tourist and recreational potential ; border areas ; state support measures ; Leontief model ; Dirichlet distribution ; uncertainty analysis ; workforce ; disaster ; business environment ; pandemic impact ; transformation ; socioeconomic model ; Anglo-Saxon model ; Rhenish (German) model ; Scandinavian (Swedish) model ; Japanese model ; Chinese model ; Stringency Index ; World Pandemic Uncertainty Index ; n/a
Language	English
Size	1 electronic resource (346 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030377358
ISBN	9783036577975 ; 3036577971
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Corporate Finance, Governance, and Social Responsibility

Gherghina, Ştefan Cristian / Gherghina, Ştefan Cristian

2023

Keywords	Development economics & emerging economies ; capital structure ; New Technology-Based Firms (NTBFs) ; internal and external innovativeness ; intangibility ; corporate governance ; information disclosure ; timeliness of financial reporting ; law violation ; private firms ; corporate governance best practice ; corporate governance compliance ; company value ; Warsaw Stock Exchange ; accrual earnings management ; Nordic model ; zero-debt policy ; flexibility ; tax shield ; free cash flow problem ; debt overhang ; dividend policy ; emerging economy ; profitability ; working capital management ; employee stock option plans ; executive compensation ; firm performance ; New Zealand ; financial derivatives ; Shenzhen stock exchange of China ; state-owned companies ; private-owned enterprises ; performance ; measurement of performance ; EVA ; strategies ; business success ; Romanian stock market ; volatility clustering ; autocorrelation ; COVID-19 ; GARCH models ; vector autoregression model ; Granger causality ; CSR practice ; financial performance ; environmental social and governance (ESG) ; board size ; independent board members ; return on equity ; Romania ; boards of directors ; Egypt ; gender diversity ; Egyptian Revolution ; investor relations ; Bucharest Stock Exchange ; firm efficiency ; data envelopment analysis (DEA) ; pharmaceutical, cosmetic and detergent (PCD) firms ; Greece ; agency ; corporate social responsibility ; information environment ; distress risk ; trade credit ; LGBT ; market value ; resource-based theory ; sexual orientation and identity ; simultaneous equations ; protection of minority investors ; stock market development ; economic growth ; board diversity ; CEO characteristics ; board committees ; ownership concentration ; agency theory ; COVID-19 pandemic ; Iran ; global economy ; financial management ; corporate social responsibility reports ; mandatory disclosure ; mandatory assurance ; analyst forecast accuracy ; analyst forecast dispersion ; board independence ; bankruptcy risk ; Europe ; corporate sustainability ; environmental ; social ; failure risk ; nonbinding voting ; shareholder activism ; systematic risk ; risk management practices ; performance outcome ; strategy ; supply chain ; capital budgeting ; capital budgeting practices ; footwear industry ; metalworking industry ; manufacturing ; SMEs ; equity investments ; property and liability insurers ; financial crisis ; n/a
Language	English
Size	1 electronic resource (534 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030381497
ISBN	9783036580937 ; 303658093X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: The effect of multiple sclerosis therapy on gut microbiota dysbiosis: a longitudinal prospective study.

Paraschiv, Andreea-Cristina / Vacaras, Vitalie / Nistor, Cristina / Vacaras, Cristiana / Strilciuc, Stefan / Muresanu, Dafin F

Microbial cell (Graz, Austria)

2024 Volume 11, Page(s) 106–115

Abstract: Gut microbiota has complex immune functions, related to different pathologies, including multiple sclerosis (MS).This study evaluated the influence of treatments on gut microbiota in people with MS (PwMS). The research comprised 60 participants, ... ...

Abstract	Gut microbiota has complex immune functions, related to different pathologies, including multiple sclerosis (MS).This study evaluated the influence of treatments on gut microbiota in people with MS (PwMS). The research comprised 60 participants, including 39 PwMS and 21 healthy controls (HC). Among the PwMS, 20 were prescribed a disease-modifying therapy (DMT), either interferon beta1a or teriflunomide, while 19 received a combination of classical DMT and an immunoglobulin Y (IgY) supplement. For each participant, two sets of gut samples were collected: one at the study's outset and another after two months. Alpha and beta diversity analyses revealed no significant differences between groups. In comparison to the HC, the MS group exhibited an increase in
Language	English
Publishing date	2024-04-04
Publishing country	Austria
Document type	Journal Article
ZDB-ID	2814756-X
ISSN	2311-2638
ISSN	2311-2638
DOI	10.15698/mic2024.03.819
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Serum levels of neurofilament light chains in pediatric multiple sclerosis: a systematic review and meta-analysis.

Niculae, Alexandru-Ştefan / Niculae, Lucia-Elena / Văcăraş, Cristiana / Văcăraş, Vitalie

Journal of neurology

2023 Volume 270, Issue 10, Page(s) 4753–4762

Abstract: Background: Multiple sclerosis is a neuro-inflammatory disease that affects adults and children and causes somatic and cognitive symptoms. Diagnosis after the first clinical symptoms is challenging, involves laboratory and magnetic resonance imaging ... ...

Abstract	Background: Multiple sclerosis is a neuro-inflammatory disease that affects adults and children and causes somatic and cognitive symptoms. Diagnosis after the first clinical symptoms is challenging, involves laboratory and magnetic resonance imaging work-up and is often inconclusive unless subsequent clinical attacks occur. Neurofilament light chains are structural proteins within neurons. Levels of this marker in cerebrospinal fluid, plasma and serum are consistently higher in patients with an initial clinical demyelinating attack that later go on to develop multiple sclerosis. Evidence concerning serum levels of this biomarker in children with multiple sclerosis is scarce. Our aim is to review and analyze the evidence available for patients with multiple sclerosis, under the age of 18. Methods: We conducted a systematic search of PubMed/Medline, Embase, Cochrane Database, and ProQuest. Human studies that provided data on serum levels of Neurofilament light chains in pediatric patients with MS, measured at the time of the first demyelinating attack and before treatment were included in meta-analysis. Results: Three studies satisfied the inclusion criteria. 157 pediatric patients with multiple sclerosis and 270 hospital-based controls that did not present with this condition were included in the analysis. A fixed effects meta-analysis showed that the standardized mean difference between patients and controls is 1.82, with a 95% confidence interval of [1.56-2.08]. Conclusion: Pediatric patients with multiple sclerosis show higher levels of serum neurofilament light chains at their first clinical demyelinating attack compared to pediatric hospital-based controls.
MeSH term(s)	Adult ; Humans ; Child ; Multiple Sclerosis/diagnosis ; Intermediate Filaments ; Biomarkers ; Neurofilament Proteins ; Magnetic Resonance Imaging
Chemical Substances	Biomarkers ; Neurofilament Proteins
Language	English
Publishing date	2023-07-02
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	187050-6
ISSN	1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
ISSN (online)	1432-1459
ISSN	0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
DOI	10.1007/s00415-023-11841-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Performance Assessment of Three Similar Dental Restorative Composite Materials via Raman Spectroscopy Supported by Complementary Methods Such as Hardness and Density Measurements.

Iordache, Stefan-Marian / Iordache, Ana-Maria / Gatin, Dina Ilinca / Grigorescu, Cristiana Eugenia Ana / Ilici, Roxana Romanita / Luculescu, Catalin-Romeo / Gatin, Eduard

Polymers

2024 Volume 16, Issue 4

Abstract: 1) Background: A widespread problem in oral health is cavities produced by cariogenic bacteria that consume fermentable carbohydrates and lower pH to 5.5-6.5, thus extracting ... ...

Abstract	(1) Background: A widespread problem in oral health is cavities produced by cariogenic bacteria that consume fermentable carbohydrates and lower pH to 5.5-6.5, thus extracting Ca
Language	English
Publishing date	2024-02-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym16040466
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Anti-bradycardia pacing-impact on patients with HFpEF: a systematic review.

Ababei, Alexandru / Hrib, Luciana Andreea / Iancu, Adalia Cristiana / Hadarag, Andra-Valeria / Khebbaiz, Ahmad / Vătășescu, Radu / Bogdan, Ștefan

Heart failure reviews

2024 Volume 29, Issue 2, Page(s) 523–534

Abstract: Heart failure with preserved ejection fraction (HFpEF) has become an emerging concern. The protective effect of bradycardia in patients with reduced ejection fraction using beta-blockers or ivabradine does not improve symptoms in HFpEF. This review aims ... ...

Abstract	Heart failure with preserved ejection fraction (HFpEF) has become an emerging concern. The protective effect of bradycardia in patients with reduced ejection fraction using beta-blockers or ivabradine does not improve symptoms in HFpEF. This review aims to assess current data regarding the impact of anti-bradycardia pacing in patients with HFpEF. A search was conducted on PubMed, ScienceDirect, Springer, and Wiley Online Library, selecting studies from 2013 to 2023. Relevant and eligible prospective studies and randomized controlled trials were included. Functional status, quality of life, and echocardiographic parameters were assessed. Six studies conformed to the selection criteria. Four were prospective studies with a total of 90 patients analyzed. Two were randomized controlled trials with a total of 129 patients assessed. The 6-min walk test (6MWT) and the Minnesota Living with Heart Failure Questionnaire (MLHFQ) score improved in all prospective studies. My-PACE trial showed improvements in MLHFQ score (p < 0.001), significant relative lowering in NT-proBNP levels (p = 0.02), and an increased mean daily activity in the personalized accelerated pacing group compared to usual care. RAPID-HF trial proved that pacemaker implantation to enhance exercise heart rate (HR) did not improve exercise capacity and was associated with increased adverse events. HFpEF requires a more individualized approach and quality of life management. This review demonstrates that higher resting HR by atrial pacing may improve symptoms and even outcomes in HFpEF, while a higher adaptive rate during exertion has not been proven beneficial.
MeSH term(s)	Humans ; Bradycardia ; Heart Failure/complications ; Heart Failure/therapy ; Heart Failure/diagnosis ; Ventricular Function, Left/physiology ; Stroke Volume/physiology ; Quality of Life ; Prospective Studies ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2024-01-28
Publishing country	United States
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	1336499-6
ISSN	1573-7322 ; 1382-4147
ISSN (online)	1573-7322
ISSN	1382-4147
DOI	10.1007/s10741-024-10382-1
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Article ; Online: Dysbiosis in Multiple Sclerosis: Can Immunoglobulin Y Supplements Help?

Paraschiv, Andreea Cristina / Vacaras, Vitalie / Nistor, Cristina / Vacaras, Cristiana / Nistor, Dorian Traian / Vesa, Stefan Cristian / Ilut, Silvina / Muresanu, Dafin F

Journal of gastrointestinal and liver diseases : JGLD

2024 Volume 33, Issue 1, Page(s) 115–122

Abstract: The role of gut microbiota in autoimmune disorders like multiple sclerosis is gaining attention. Multiple sclerosis is characterized by inflammation, demyelination, and neurodegeneration in the central nervous system. Alterations in gut microbiota have ... ...

Abstract	The role of gut microbiota in autoimmune disorders like multiple sclerosis is gaining attention. Multiple sclerosis is characterized by inflammation, demyelination, and neurodegeneration in the central nervous system. Alterations in gut microbiota have been linked to multiple sclerosis development, with decreased beneficial bacteria and increased harmful species. The gut-brain axis is a complex interface influencing bidirectional interactions between the gut and the brain. Dysbiosis, an imbalance in gut microbiota, has been associated with autoimmune diseases. The influence of gut microbiota in multiple sclerosis is reversible, making it a potential therapeutic target. Probiotics, prebiotics, and fecal microbiota transplantation have shown promise in multiple sclerosis treatment, with positive effects on inflammation and immune regulation. Immunoglobulin Y (IgY) supplements derived from chicken egg yolk have potential as nutraceuticals or dietary supplements. IgY technology has been effective against various infections, and studies have highlighted its role in modulating gut microbiota and immune responses. Clinical trials using IgY supplements in multiple sclerosis are limited but have shown positive outcomes, including reduced symptoms, and altered immune responses. Future research directions involve understanding the mechanisms of IgY's interaction with gut microbiota, optimal dosage determination, and long-term safety assessments. Combining IgY therapy with other interventions and investigating correlations between microbiota changes and clinical outcomes are potential avenues for advancing multiple sclerosis treatment with IgY supplements.
MeSH term(s)	Humans ; Multiple Sclerosis/therapy ; Dysbiosis/microbiology ; Dysbiosis/therapy ; Dietary Supplements/adverse effects ; Probiotics/therapeutic use ; Inflammation ; Autoimmune Diseases ; Immunoglobulins
Chemical Substances	IgY ; Immunoglobulins
Language	English
Publishing date	2024-03-30
Publishing country	Romania
Document type	Journal Article ; Review
ZDB-ID	2427021-0
ISSN	1842-1121 ; 1841-8724
ISSN (online)	1842-1121
ISSN	1841-8724
DOI	10.15403/jgld-5241
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Brain-Derived Neurotrophic Factor in Multiple Sclerosis Disability: A Prospective Study.

Vacaras, Vitalie / Paraschiv, Andreea-Cristina / Iluț, Silvina / Vacaras, Cristiana / Nistor, Cristina / Marin, Gheorghe-Eduard / Schiopu, Andra Maria / Nistor, Dorian-Traian / Vesa, Ștefan Cristian / Mureșanu, Dafin Fior

Brain sciences

2024 Volume 14, Issue 3

Abstract: Multiple sclerosis (MS) is a demyelinating central nervous system disease that leads to neurological disability. Brain-derived neurotrophic factors (BDNFs) are neurotrophins involved in neurodegenerative disorders. This study analysed the relationship ... ...

Abstract	Multiple sclerosis (MS) is a demyelinating central nervous system disease that leads to neurological disability. Brain-derived neurotrophic factors (BDNFs) are neurotrophins involved in neurodegenerative disorders. This study analysed the relationship between serum BDNF, neurological disability and different MS treatments. We included 63 people with MS (PwMS), with relapsing-remitting MS or clinically isolated syndrome, and 16 healthy controls (HCs). We analysed the serum levels of BDNF and MS specific disability tests (Expanded Disability Status Scale, timed 25-foot walk test, nine-hole peg test), at baseline (V0) and after one year of interferon beta1a or teriflunomide treatment (V1). Baseline BDNF values were not different between the PwMS and HCs (
Language	English
Publishing date	2024-02-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci14030243
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical Aspects and Therapeutic Management of an Aggressive Manifestation of Stage III Grade C Periodontitis in a Female Teenager

Stana Păunica / Marina-Cristina Giurgiu / Dragoș Nicolae Ciongaru / Cristiana-Elena Pădure / Ștefan Dimitrie Albu / Silviu-Mirel Pițuru / Anca Silvia Dumitriu

Diagnostics, Vol 13, Iss 1077, p

2023 Volume 1077

Abstract: The main objective of this study was to evaluate the improvement of periodontal health in patients with periodontitis treated with non-surgical periodontal therapy and subgingival-administrated local and systemic antimicrobial agents. A female teenager ... ...

Abstract	The main objective of this study was to evaluate the improvement of periodontal health in patients with periodontitis treated with non-surgical periodontal therapy and subgingival-administrated local and systemic antimicrobial agents. A female teenager with periodontitis-associated health issues and a history of dental trauma was selected for this study. Clinical indices were obtained, and radiographic examination was performed at the beginning of the study. The patient was treated with periodontal therapy and administration of antibiotics. After this therapy, visits were scheduled at regular intervals to observe the clinical changes. Non-surgical periodontal therapy and administration of local and systemic antibiotics resulted in a reduction in the patient pocket depth probing, plaque index, and bleeding on probing. Gingival and periodontal health improved in terms of gingival overgrowth, plaque, tartar index, and tooth mobility. Suppuration was eliminated, and no gingival inflammation signs were observed.
Keywords	antibiotics ; bone loss ; gingival overgrowth ; molar/incisor pattern ; periodontal therapy ; aggressive periodontitis ; Medicine (General) ; R5-920
Subject code	610 ; 616
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spectro-Electrochemical Properties of A New Non-Enzymatic Modified Working Electrode Used for Histamine Assessment in the Diagnosis of Food Poisoning

Iordache, Stefan-Marian / Iordache, Ana-Maria / Zubarev, Alexei / Caramizoiu, Stefan / Grigorescu, Cristiana Eugenia Ana / Marinescu, Silviu / Giuglea, Carmen

Foods. 2023 July 31, v. 12, no. 15

2023

Abstract: We successfully prepared a non-enzymatic sensor based on a graphene-thiophene composite for histamine detection. The self-assembling properties of the thiophene onto Au support and the high electrical conductivity of graphene encouraged the choice of ... ...

Abstract	We successfully prepared a non-enzymatic sensor based on a graphene-thiophene composite for histamine detection. The self-assembling properties of the thiophene onto Au support and the high electrical conductivity of graphene encouraged the choice of this type of composite. The composite was deposited via electrochemical polymerization onto the Au layer of a screen-printed microelectrode. The electropolymerization and electrochemical detection of histamine were both achieved by cyclic voltammetry. Two types of electrolytes were used for the electrochemical detection: (a) phosphate buffer solution (PBS), which showed low-intensity redox peaks for histamine; and (b) trichloroacetic acid (TCA) 0.01 M, which showed improved results over PBS and did not damage the microelectrode. For the concentration range of 100–200 mg/kg, the sensor shows a linear regression pattern for the oxidation peak fitted on the equation Iₚₐ = 123.412 + 0.49933 ×x, with R² = 0.94178. The lowest limit of detection was calculated to be 13.8 mg/kg and the limit of quantification was calculated at 46 mg/kg. These results are important since by monitoring the amount of histamine in a food product, early onset of spoilage can be easily detected, thus reducing foodborne poisoning and food waste (by recycling products that are still edible).
Keywords	detection limit ; electrical conductivity ; electrochemistry ; electrodes ; equations ; food waste ; foods ; graphene ; histamine ; oxidation ; phosphates ; polymerization ; regression analysis ; spoilage ; thiophene ; trichloroacetic acid ; voltammetry
Language	English
Dates of publication	2023-0731
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12152908
Database	NAL-Catalogue (AGRICOLA)

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