Article: Loss of Long Distance Co-Expression in Lung Cancer.
2021 Volume 12, Page(s) 625741
Abstract: Lung cancer is one of the deadliest, most aggressive cancers. Abrupt changes in gene expression represent an important challenge to understand and fight the disease. Gene co-expression networks (GCNs) have been widely used to study the genomic regulatory ...
Abstract | Lung cancer is one of the deadliest, most aggressive cancers. Abrupt changes in gene expression represent an important challenge to understand and fight the disease. Gene co-expression networks (GCNs) have been widely used to study the genomic regulatory landscape of human cancer. Here, based on 1,143 RNA-Seq experiments from the TCGA collaboration, we constructed GCN for the most common types of lung tumors: adenocarcinoma (TAD) and squamous cells (TSCs) as well as their respective control networks (NAD and NSC). We compared the number of intra-chromosome ( |
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Language | English |
Publishing date | 2021-03-10 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2606823-0 |
ISSN | 1664-8021 |
ISSN | 1664-8021 |
DOI | 10.3389/fgene.2021.625741 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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