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  1. Book: Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów / Czȩść 2. Nowotwory i rozrosty rzekomonowotworowe / Leszek Woźniak ; Wojciech Biernat

    Woźniak, Leszek / Giryn-Rokosz, Iwona / Biernat, Wojciech

    (Patologia polska ; 43, Suppl. 2)

    1992  

    Series title Patologia polska ; 43, Suppl. 2
    Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Collection Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Language Polish ; English
    Size 51 S. : überw. Ill.
    Publisher Akad. Med., Katedra Onkologii
    Publishing place Łódź
    Publishing country Poland
    Document type Book
    HBZ-ID HT007171465
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 377 -43,Suppl.2- verfügbar in Königswinter Königswinter

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  2. Book: Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów / Czȩść 2. Nowotwory i rozrosty rzekomonowotworowe / Leszek Woźniak ; Wojciech Biernat ; Hanna Saryusz-Wolska

    Woźniak, Leszek / Giryn-Rokosz, Iwona / Biernat, Wojciech

    (Patologia polska ; 43, Suppl. 1)

    1992  

    Series title Patologia polska ; 43, Suppl. 1
    Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Collection Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Language Polish ; English
    Size 42 S. : überw. Ill.
    Publisher Akad. Med., Katedra Onkologii
    Publishing place Łódź
    Publishing country Poland
    Document type Book
    HBZ-ID HT007171461
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 377 -43,Suppl.1- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book: Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów / Czȩść 2. Nowotwory i rozrosty rzekomonowotworowe / Leszek Woźniak ; Wojciech Biernat ; Iwona Giryn-Rokosz

    Woźniak, Leszek / Giryn-Rokosz, Iwona / Biernat, Wojciech

    (Patologia polska ; 42, Suppl. 4)

    1991  

    Series title Patologia polska ; 42, Suppl. 4
    Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Collection Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Language Polish ; English
    Size 42 S. : überw. Ill.
    Publisher Akad. Med., Katedra Onkologii
    Publishing place Łódź
    Publishing country Poland
    Document type Book
    HBZ-ID HT007171456
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 377 -42,Suppl.4- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Book: Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów / Czȩść 2. Nowotwory i rozrosty rzekomonowotworowe / Leszek Woźniak ; Wojciech Biernat ; Iwona Giryn-Rokosz

    Woźniak, Leszek / Giryn-Rokosz, Iwona / Biernat, Wojciech

    (Patologia polska ; 42, Suppl. 3)

    1991  

    Series title Patologia polska ; 42, Suppl. 3
    Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Collection Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Language Polish ; English
    Size 36 S. : überw. Ill.
    Publisher Akad. Med., Katedra Onkologii
    Publishing place Łódź
    Publishing country Poland
    Document type Book
    HBZ-ID HT007171453
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 377 -42,Suppl.3- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book: Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów / Czȩść 2. Nowotwory i rozrosty rzekomonowotworowe / Leszek Woźniak ; Wojciech Biernat ; Iwona Giryn-Rokosz

    Woźniak, Leszek / Giryn-Rokosz, Iwona / Biernat, Wojciech

    (Patologia polska ; 42, Suppl. 2)

    1991  

    Series title Patologia polska ; 42, Suppl. 2
    Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Collection Atlas patomorfologicznej diagnostyki różnicowej chorób skóry ze szczególnym uwzględnieniem nowotoworów
    Language Polish ; English
    Size 31 S. : überw. Ill.
    Publisher Akad. Med., Katedra Onkologii
    Publishing place Łódź
    Publishing country Poland
    Document type Book
    HBZ-ID HT007171452
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 377 -42,Suppl.2- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Primary Cutaneous CD30-Positive Lymphoproliferative Disorders-Current Therapeutic Approaches with a Focus on Brentuximab Vedotin.

    Stein, Tomasz / Robak, Tadeusz / Biernat, Wojciech / Robak, Ewa

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: One of the most common subgroups of cutaneous T-cell lymphomas is that of primary cutaneous CD30-positive lymphoproliferative disorders. The group includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL), as ... ...

    Abstract One of the most common subgroups of cutaneous T-cell lymphomas is that of primary cutaneous CD30-positive lymphoproliferative disorders. The group includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL), as well as some borderline cases. Recently, significant progress has been made in understanding the genetics and treatment of these disorders. This review article summarises the clinical evidence supporting the current treatment options for these diseases. Recent years have seen the introduction of novel agents into clinical practice; most of these target CD30, such as anti-CD30 monoclonal antibodies and conjugated antibodies (brentuximab vedotin), bispecific antibodies and cellular therapies, particularly anti-CD30 CAR-T cells. This paper briefly reviews the biology of CD30 that makes it a good therapeutic target and describes the anti-CD30 therapies that have emerged to date.
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Great mimicker - a case of occult melanoma displaying ganglioneuroblastic differentiation.

    Skrzypkowska, Paulina / Kunc, Michał / Biernat, Wojciech

    Contemporary oncology (Poznan, Poland)

    2023  Volume 27, Issue 2, Page(s) 118–121

    Abstract: Melanomas are known for their diverse morphological features, presenting a diagnostic challenge for pathologists. Uncommon variations of melanoma can exhibit distinct cytological and histomorphological characteristics, including ganglioneuroblastic ... ...

    Abstract Melanomas are known for their diverse morphological features, presenting a diagnostic challenge for pathologists. Uncommon variations of melanoma can exhibit distinct cytological and histomorphological characteristics, including ganglioneuroblastic differentiation. However, this phenomenon is extremely rare, with only a few documented cases. Here, we present a unique case of an occult metastatic melanoma with ganglioneuroblastic differentiation developing in a 76-year-old male. The diagnosis was based on histopathology, immunophenotyping, and molecular testing, which revealed SOX10 positivity and an NRAS mutation. Notably, classic melanoma markers HMB45 and melan-A were negative, highlighting the importance of considering alternative markers. This case emphasizes the significance of immunohistochemistry and molecular investigation in diagnosing melanomas with unusual features and identifying appropriate candidates for immune checkpoint therapy. Additionally, the occurrence of ganglioneuroblastic differentiation further supports a shared histogenetic origin from the neural crest. Improved understanding of such rare variants contributes to accurate diagnosis and optimal management of melanoma patients.
    Language English
    Publishing date 2023-08-22
    Publishing country Poland
    Document type Case Reports
    ISSN 1428-2526
    ISSN 1428-2526
    DOI 10.5114/wo.2023.130966
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Diagnostic test accuracy meta-analysis of PRAME in distinguishing primary cutaneous melanomas from benign melanocytic lesions.

    Kunc, Michał / Żemierowska, Natalia / Skowronek, Filip / Biernat, Wojciech

    Histopathology

    2023  Volume 83, Issue 1, Page(s) 3–14

    Abstract: PRAME is a novel immunohistochemical marker that aids the diagnosis of melanocytic lesions. Diffuse PRAME positivity suggests melanoma, whereas benign naevi are negative or only weakly positive. However, the factual diagnostic accuracy of PRAME is not ... ...

    Abstract PRAME is a novel immunohistochemical marker that aids the diagnosis of melanocytic lesions. Diffuse PRAME positivity suggests melanoma, whereas benign naevi are negative or only weakly positive. However, the factual diagnostic accuracy of PRAME is not well established. Moreover, some studies have suggested that the threshold of 3+/50% positive cells may be more useful in practice than the most widely used cut-off (4+/75% of positive cells). Hence, we performed a systematic review and diagnostic accuracy meta-analysis to evaluate sensitivity, specificity, likelihood ratios and optimal threshold for PRAME in distinguishing benign melanocytic proliferations from melanomas. Twenty-six studies were enrolled into the meta-analysis. A total of 2915 melanocytic lesions were analysed. The optimal threshold for PRAME positivity was estimated at 3.11, which translates into 3+ in practice. Sensitivity and specificity calculated from SROC at the 3+ threshold were 0.735 (0.631-0.818) and 0.915 (0.834-0.958), respectively, compared to 0.679 (0.559-0.957) and 0.957 (0.908-0.981) at the 4+ cut-off. In subgroup analysis, the spitzoid subgroup was characterised by the lowest sensitivity and diagnostic odds ratio of PRAME. Our findings indicate that PRAME immunohistochemistry may serve as an ancillary marker to support the diagnosis of melanoma. Nevertheless, the accuracy of PRAME may be lower in spitzoid neoplasms. Our meta-analysis suggests that the 3+/50% threshold might be more useful in practice than the 4+/75% cut-off, as it shows higher sensitivity with retained satisfactory specificity.
    MeSH term(s) Humans ; Melanoma/diagnosis ; Melanoma/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Melanocytes/pathology ; Diagnostic Tests, Routine ; Antigens, Neoplasm/analysis ; Melanoma, Cutaneous Malignant
    Chemical Substances Antigens, Neoplasm ; PRAME protein, human
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Systematic Review ; Meta-Analysis ; Journal Article ; Review
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.14904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1328: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Skene's gland adenocarcinoma coexisting with infiltrating urothelial carcinoma of the urinary bladder.

    Kunc, Michał / Biernat, Wojciech

    Polish journal of pathology : official journal of the Polish Society of Pathologists

    2021  Volume 72, Issue 2, Page(s) 170–173

    Abstract: A 78-year-old woman underwent radical cystectomy due to high-grade infiltrating urothelial carcinoma of the urinary bladder. Histopathological examination of the bladder neck revealed coincidental urothelial carcinoma and tubular neoplasm resembling ... ...

    Abstract A 78-year-old woman underwent radical cystectomy due to high-grade infiltrating urothelial carcinoma of the urinary bladder. Histopathological examination of the bladder neck revealed coincidental urothelial carcinoma and tubular neoplasm resembling prostatic acinar adenocarcinoma. The latter was accompanied by a non-invasive component showing features of high-grade prostatic intraepithelial neoplasia (PIN). The lesion showed immunopositivity for prostate-specific antigen, prostein, and androgen receptor. The diagnosis of Skene's gland adenocarcinoma (SGA) was established. This is the 14th case of SGA in the literature, and the first coexisting with urothelial carcinoma. Our case demonstrates a possible origin of SGA from precursors resembling PIN.
    MeSH term(s) Adenocarcinoma ; Aged ; Carcinoma, Transitional Cell ; Humans ; Male ; Prostatic Neoplasms ; Urethral Neoplasms ; Urinary Bladder Neoplasms
    Language English
    Publishing date 2021-09-24
    Publishing country Poland
    Document type Case Reports
    ZDB-ID 1283064-1
    ISSN 1233-9687 ; 0031-3114
    ISSN 1233-9687 ; 0031-3114
    DOI 10.5114/pjp.2021.109520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 377: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia

    Urszula Maińska / Martyna Sławińska / Wojciech Baran / Wojciech Biernat / Aleksandra Sejda / Roman Nowicki / Michał Sobjanek

    Przegląd Dermatologiczny, Vol 109, Iss 6, Pp 453-

    2023  Volume 459

    Keywords xanthogranuloma necrobioticum ; monoclonal gammopathy ; neutropenia ; triamcinolone acetate ; intravenous immunoglobulin preparations ; Medicine ; R ; Dermatology ; RL1-803
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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