LIVIVO - Search results -

Search results

Result 1 - 9 of total 9

Search options

Article ; Online: Screening and Treatment of Tobacco Use Disorder in Mental Health Clinics in New York State: Current Status and Potential Next Steps.

Zern, Adria / Seserman, Michael / Dacus, Heather / Wallace, Barbara / Friedlander, Susan / Manseau, Marc W / Smalling, Maxine M / Smith, Thomas E / Williams, Jill M / Compton, Michael T

Community mental health journal

2020 Volume 57, Issue 6, Page(s) 1023–1031

Abstract: The prevalence of smoking is higher among individuals with serious mental illnesses than the general population. Evidence-based practices exist for tobacco cessation, but little is known about mental health clinics' tobacco cessation treatment practices/ ... ...

Abstract	The prevalence of smoking is higher among individuals with serious mental illnesses than the general population. Evidence-based practices exist for tobacco cessation, but little is known about mental health clinics' tobacco cessation treatment practices/protocols. Mental health clinics in New York State were surveyed about their tobacco use treatment protocols and outdoor-smoking policies. One-third of clinics were not providing individual counseling for tobacco use disorder, 39% were not prescribing nicotine replacement therapy, and nearly half reported not prescribing bupropion or varenicline. Even smaller proportions reported implementing other clinical practice guidelines, with only 25.2% providing staff training and 20.3% having a dedicated staff member for coordinating tobacco use disorder treatment. Regarding outdoor smoke-free policies, 38% of clinics reported not allowing any tobacco use anywhere on grounds. Despite some successes, many clinics do not provide evidence-based tobacco use treatments, meaning important opportunities exist for mental health clinics and oversight agencies to standardize practices.
MeSH term(s)	Humans ; Mental Health ; New York/epidemiology ; Smoking Cessation ; Tobacco Use Cessation Devices ; Tobacco Use Disorder
Language	English
Publishing date	2020-10-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	215855-3
ISSN	1573-2789 ; 0010-3853
ISSN (online)	1573-2789
ISSN	0010-3853
DOI	10.1007/s10597-020-00726-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 557: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: Preservation of native aortic valve flow and full hemodynamic support with the TORVAD using a computational model of the cardiovascular system.

Gohean, Jeffrey R / George, Mitchell J / Chang, Kay-Won / Larson, Erik R / Pate, Thomas D / Kurusz, Mark / Longoria, Raul G / Smalling, Richard W

ASAIO journal (American Society for Artificial Internal Organs : 1992)

2015 Volume 61, Issue 3, Page(s) 259–265

Abstract: This article describes the stroke volume selection and operational design for the toroidal ventricular assist device (TORVAD), a synchronous, positive-displacement ventricular assist device (VAD). A lumped parameter model was used to simulate ... ...

Abstract	This article describes the stroke volume selection and operational design for the toroidal ventricular assist device (TORVAD), a synchronous, positive-displacement ventricular assist device (VAD). A lumped parameter model was used to simulate hemodynamics with the TORVAD compared with those under continuous-flow VAD support. Results from the simulation demonstrated that a TORVAD with a 30 ml stroke volume ejecting with an early diastolic counterpulse provides comparable systemic support to the HeartMate II (HMII) (cardiac output 5.7 L/min up from 3.1 L/min in simulated heart failure). By taking the advantage of synchronous pulsatility, the TORVAD delivers full hemodynamic support with nearly half the VAD flow rate (2.7 L/min compared with 5.3 L/min for the HMII) by allowing the left ventricle to eject during systole and thus preserving native aortic valve flow (3.0 L/min compared with 0.4 L/min for the HMII, down from 3.1 L/min at baseline). The TORVAD also preserves pulse pressure (26.7 mm Hg compared with 12.8 mm Hg for the HMII, down from 29.1 mm Hg at baseline). Preservation of aortic valve flow with synchronous pulsatile support could reduce the high incidence of aortic insufficiency and valve cusp fusion reported in patients supported with continuous-flow VADs.
MeSH term(s)	Computer Simulation ; Heart-Assist Devices ; Hemodynamics ; Humans ; Models, Cardiovascular
Language	English
Publishing date	2015-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	759982-1
ISSN	1538-943X ; 0162-1432 ; 1058-2916
ISSN (online)	1538-943X
ISSN	0162-1432 ; 1058-2916
DOI	10.1097/MAT.0000000000000190
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Uk I Zs.199: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.B 2435: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Anticoagulation After Surgical or Transcatheter Bioprosthetic Aortic Valve Replacement.

Journal of the American College of Cardiology

2019 Volume 74, Issue 9, Page(s) 1190–1200

Abstract: Background: There is paucity of evidence on the impact of anticoagulation (AC) after bioprosthetic aortic valve replacement (AVR) on valve hemodynamics and clinical outcomes.: Objectives: The study aimed to assess the impact of AC after bioprosthetic ...

Abstract	Background: There is paucity of evidence on the impact of anticoagulation (AC) after bioprosthetic aortic valve replacement (AVR) on valve hemodynamics and clinical outcomes. Objectives: The study aimed to assess the impact of AC after bioprosthetic AVR on valve hemodynamics and clinical outcomes. Methods: Data on antiplatelet and antithrombotic therapy were collected. Echocardiograms were performed at 30 days and 1 year post-AVR. Linear regression model and propensity-score adjusted cox proportional model were used to assess the impact of AC on valve hemodynamics and clinical outcomes, respectively. Results: A total of 4,832 patients undergoing bioprosthetic AVR (transcatheter aortic valve replacement [TAVR], n = 3,889 and surgical AVR [SAVR], n = 943) in the pooled cohort of PARTNER2 (Placement of Aortic Transcatheter Valves) randomized trials and nonrandomized registries were studied. Following adjustment for valve size, annular diameter, atrial fibrillation, and ejection fraction at the time of assessment of hemodynamics, there was no significant difference in aortic valve mean gradients or aortic valve areas between patients discharged on AC vs. those not discharged on AC, for either TAVR or SAVR cohorts. A significantly greater proportion of patients not discharged on AC had an increase in mean gradient >10 mm Hg from 30 days to 1 year, compared with those discharged on AC (2.3% vs. 1.1%, p = 0.03). There was no independent association between AC after TAVR and adverse outcomes (death, p = 0.15; rehospitalization, p = 0.16), whereas AC after SAVR was associated with significantly fewer strokes (hazard ratio [HR]: 0.17; 95% confidence interval [CI]: 0.05-0.60; p = 0.006). Conclusions: In the short term, early AC after bioprosthetic AVR did not result in adverse clinical events, did not significantly affect aortic valve hemodynamics (aortic valve gradients or area), and was associated with decreased rates of stroke after SAVR (but not after TAVR). Whether early AC after bioprosthetic AVR has impact on long-term outcomes remains to be determined. (Placement of AoRTic TraNscathetER Valves [PARTNERII A]; NCT01314313).
MeSH term(s)	Aged ; Aged, 80 and over ; Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Aortic Valve/drug effects ; Aortic Valve/physiology ; Aortic Valve/surgery ; Bioprosthesis ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/methods ; Hemodynamics/drug effects ; Humans ; Male ; Postoperative Period ; Prospective Studies ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
Chemical Substances	Anticoagulants
Language	English
Publishing date	2019-09-11
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2019.06.058
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Verification of a computational cardiovascular system model comparing the hemodynamics of a continuous flow to a synchronous valveless pulsatile flow left ventricular assist device.

Gohean, Jeffrey R / George, Mitchell J / Pate, Thomas D / Kurusz, Mark / Longoria, Raul G / Smalling, Richard W

ASAIO journal (American Society for Artificial Internal Organs : 1992)

2013 Volume 59, Issue 2, Page(s) 107–116

Abstract: The purpose of this investigation is to use a computational model to compare a synchronized valveless pulsatile left ventricular assist device with continuous flow left ventricular assist devices at the same level of device flow, and to verify the model ... ...

Abstract	The purpose of this investigation is to use a computational model to compare a synchronized valveless pulsatile left ventricular assist device with continuous flow left ventricular assist devices at the same level of device flow, and to verify the model with in vivo porcine data. A dynamic system model of the human cardiovascular system was developed to simulate the support of a healthy or failing native heart from a continuous flow left ventricular assist device or a synchronous pulsatile valveless dual-piston positive displacement pump. These results were compared with measurements made during in vivo porcine experiments. Results from the simulation model and from the in vivo counterpart show that the pulsatile pump provides higher cardiac output, left ventricular unloading, cardiac pulsatility, and aortic valve flow as compared with the continuous flow model at the same level of support. The dynamic system model developed for this investigation can effectively simulate human cardiovascular support by a synchronous pulsatile or continuous flow ventricular assist device.
MeSH term(s)	Animals ; Computer Simulation ; Heart Failure/physiopathology ; Heart-Assist Devices ; Hemodynamics ; Humans ; Models, Cardiovascular ; Pulmonary Circulation ; Pulsatile Flow ; Swine
Language	English
Publishing date	2013-01-01
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	759982-1
ISSN	1538-943X ; 0162-1432 ; 1058-2916
ISSN (online)	1538-943X
ISSN	0162-1432 ; 1058-2916
DOI	10.1097/MAT.0b013e31827db6d4
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.199: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.B 2435: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Molecular approaches to detecting herpes simplex virus and enteroviruses in the central nervous system.

Smalling, Thomas W / Sefers, Susan E / Li, Haijing / Tang, Yi-Wei

Journal of clinical microbiology

2001 Volume 40, Issue 7, Page(s) 2317–2322

MeSH term(s)	Base Sequence ; Central Nervous System/virology ; Central Nervous System Infections/diagnosis ; Central Nervous System Infections/virology ; DNA Primers/genetics ; Enterovirus/genetics ; Enterovirus/isolation & purification ; Enterovirus Infections/diagnosis ; Enterovirus Infections/virology ; Herpes Simplex/diagnosis ; Herpes Simplex/virology ; Humans ; Polymerase Chain Reaction/methods ; Polymerase Chain Reaction/standards ; Quality Control ; Simplexvirus/genetics ; Simplexvirus/isolation & purification
Chemical Substances	DNA Primers
Language	English
Publishing date	2001-10-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	390499-4
ISSN	1098-660X ; 0095-1137
ISSN (online)	1098-660X
ISSN	0095-1137
DOI	10.1128/JCM.40.7.2317-2322.2002
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1188: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Improved left ventricular unloading and circulatory support with synchronized pulsatile left ventricular assistance compared with continuous-flow left ventricular assistance in an acute porcine left ventricular failure model.

Letsou, George V / Pate, Thomas D / Gohean, Jeffrey R / Kurusz, Mark / Longoria, Raul G / Kaiser, Larry / Smalling, Richard W

The Journal of thoracic and cardiovascular surgery

2010 Volume 140, Issue 5, Page(s) 1181–1188

Abstract: Objective: Controversy exists regarding the optimal pumping method for left ventricular assist devices. The purpose of this investigation was to test the hypothesis that pulsatile left ventricular assist synchronized to the cardiac cycle provides ... ...

Abstract	Objective: Controversy exists regarding the optimal pumping method for left ventricular assist devices. The purpose of this investigation was to test the hypothesis that pulsatile left ventricular assist synchronized to the cardiac cycle provides superior left ventricular unloading and circulatory support compared with continuous-flow left ventricular assist devices at the same level of ventricular assist device flow. Methods: Seven male pigs were used to evaluate left ventricular assist device function using the TORVAD synchronized pulsatile-flow pump (Windmill Cardiovascular Systems, Inc, Austin, Tex) compared with the Bio-Medicus BPX-80 continuous-flow centrifugal pump (Medtronic, Inc, Minneapolis, Minn). Experiments were carried out under general anesthesia, and animals were instrumented via a median sternotomy. Hemodynamic measurements were obtained in the control state and with left ventricular assistance using the TORVAD and BPX-80 individually. Left ventricular failure was induced with suture ligation of the mid-left anterior descending coronary artery, and hemodynamic measurements were repeated. Results: During left ventricular assist device support, mean aortic pressure and total cardiac output were higher and left atrial pressure was lower with pulsatile compared with continuous flow at the same ventricular assist device flow rate. During ischemic left ventricular failure, pulsatile left ventricular support resulted in higher total cardiac output (5.58 ± 1.58 vs 5.12 ± 1.19, P < .05), higher mean aortic pressure (67.8 ± 14 vs 60.2 ± 10, P < .05), and lower left atrial pressure (11.5 ± 3.5 vs 13.9 ± 6.0, P < .05) compared with continuous flow at the same left ventricular assist device flow rate. Conclusion: Synchronized, pulsatile left ventricular assistance produces superior left ventricular unloading and circulatory support compared with continuous-flow left ventricular assist at the same flow rates.
MeSH term(s)	Acute Disease ; Animals ; Aorta/physiopathology ; Atrial Function, Left ; Blood Pressure ; Cardiac Output ; Disease Models, Animal ; Heart Failure/physiopathology ; Heart Failure/therapy ; Heart-Assist Devices ; Hemodynamics ; Male ; Prosthesis Design ; Pulsatile Flow ; Sus scrofa ; Time Factors ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Dysfunction, Left/therapy ; Ventricular Function, Left
Language	English
Publishing date	2010-11
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2010.03.043
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.104: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement.

Yoon, Sung-Han / Bleiziffer, Sabine / Latib, Azeem / Eschenbach, Lena / Ancona, Marco / Vincent, Flavien / Kim, Won-Keun / Unbehaum, Axel / Asami, Masahiko / Dhoble, Abhijeet / Silaschi, Miriam / Frangieh, Antonio H / Veulemans, Verena / Tang, Gilbert H L / Kuwata, Shingo / Rampat, Rajiv / Schmidt, Tobias / Patel, Amisha J / Nicz, Pedro Felipe Gomez /

Nombela-Franco, Luis / Kini, Annapoorna / Kitamura, Mitsunobu / Sharma, Rahul / Chakravarty, Tarun / Hildick-Smith, David / Arnold, Martin / de Brito, Fabio Sandoli / Jensen, Christoph / Jung, Christian / Jilaihawi, Hasan / Smalling, Richard W / Maisano, Francesco / Kasel, Albert Markus / Treede, Hendrik / Kempfert, Joerg / Pilgrim, Thomas / Kar, Saibal / Bapat, Vinayak / Whisenant, Brian K / Van Belle, Eric / Delgado, Victoria / Modine, Thomas / Bax, Jeroen J / Makkar, Raj R

JACC. Cardiovascular interventions

2019 Volume 12, Issue 2, Page(s) 182–193

Abstract: Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR).: Background: LVOT obstruction is a major concern with TMVR, but limited data ... ...

Abstract	Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Background: LVOT obstruction is a major concern with TMVR, but limited data exist regarding its predictors and impact on outcomes. Methods: Patients with pre-procedural multidetector row computed tomography (MDCT) undergoing TMVR for failed mitral bioprosthetic valves (valve-in-valve), annuloplasty rings (valve-in-ring), and mitral annular calcification (valve-in-MAC) were included in this study. Echocardiographic and procedural characteristics were recorded, and comprehensive assessment with MDCT was performed to identify the predictors of LVOT obstruction (defined as an increment of mean LVOT gradient ≥10 mm Hg from baseline). The new LVOT (neo-LVOT) area left after TMVR was estimated by embedding a virtual valve into the mitral annulus on MDCT, simulating the procedure. Results: Among 194 patients with pre-procedural MDCT undergoing TMVR (valve-in-valve, 107 patients; valve-in-ring, 50 patients; valve-in-MAC, 37 patients), LVOT obstruction was observed in 26 patients (13.4%), with a higher rate after valve-in-MAC than valve-in-ring and valve-in-valve (54.1% vs. 8.0% vs. 1.9%; p < 0.001). Patients with LVOT obstruction had significantly higher procedural mortality compared with those without LVOT obstruction (34.6% vs. 2.4%; p < 0.001). Receiver-operating characteristic curve analysis showed that an estimated neo-LVOT area ≤1.7 cm Conclusions: LVOT obstruction after TMVR was associated with higher procedural mortality. A small estimated neo-LVOT area was significantly associated with LVOT obstruction after TMVR and may help identify patients at high risk for LVOT obstruction.
MeSH term(s)	Aged ; Aged, 80 and over ; Calcinosis/diagnostic imaging ; Calcinosis/mortality ; Calcinosis/physiopathology ; Calcinosis/surgery ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Cardiac Catheterization/mortality ; Echocardiography ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/instrumentation ; Heart Valve Prosthesis Implantation/mortality ; Humans ; Male ; Mitral Valve/diagnostic imaging ; Mitral Valve/physiopathology ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/mortality ; Mitral Valve Insufficiency/physiopathology ; Mitral Valve Insufficiency/surgery ; Mitral Valve Stenosis/diagnostic imaging ; Mitral Valve Stenosis/mortality ; Mitral Valve Stenosis/physiopathology ; Mitral Valve Stenosis/surgery ; Multidetector Computed Tomography ; Prosthesis Design ; Prosthesis Failure ; Registries ; Risk Assessment ; Risk Factors ; Treatment Outcome ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology ; Ventricular Outflow Obstruction/mortality ; Ventricular Outflow Obstruction/physiopathology
Language	English
Publishing date	2019-01-24
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2018.12.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6669: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification.

Yoon, Sung-Han / Whisenant, Brian K / Bleiziffer, Sabine / Delgado, Victoria / Dhoble, Abhijeet / Schofer, Niklas / Eschenbach, Lena / Bansal, Eric / Murdoch, Dale J / Ancona, Marco / Schmidt, Tobias / Yzeiraj, Ermela / Vincent, Flavien / Niikura, Hiroki / Kim, Won-Keun / Asami, Masahiko / Unbehaun, Axel / Hirji, Sameer / Fujita, Buntaro /

Silaschi, Miriam / Tang, Gilbert H L / Kuwata, Shingo / Wong, S Chiu / Frangieh, Antonio H / Barker, Colin M / Davies, James E / Lauten, Alexander / Deuschl, Florian / Nombela-Franco, Luis / Rampat, Rajiv / Nicz, Pedro Felipe Gomes / Masson, Jean-Bernard / Wijeysundera, Harindra C / Sievert, Horst / Blackman, Daniel J / Gutierrez-Ibanes, Enrique / Sugiyama, Daisuke / Chakravarty, Tarun / Hildick-Smith, David / de Brito, Fabio Sandoli / Jensen, Christoph / Jung, Christian / Smalling, Richard W / Arnold, Martin / Redwood, Simon / Kasel, Albert Markus / Maisano, Francesco / Treede, Hendrik / Ensminger, Stephan M / Kar, Saibal / Kaneko, Tsuyoshi / Pilgrim, Thomas / Sorajja, Paul / Van Belle, Eric / Prendergast, Bernard D / Bapat, Vinayak / Modine, Thomas / Schofer, Joachim / Frerker, Christian / Kempfert, Joerg / Attizzani, Guilherme F / Latib, Azeem / Schaefer, Ulrich / Webb, John G / Bax, Jeroen J / Makkar, Raj R

European heart journal

2018 Volume 40, Issue 5, Page(s) 441–451

Abstract: Aims: We sought to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) for patients with degenerated bioprostheses [valve-in-valve (ViV)], failed annuloplasty rings [valve-in-ring (ViR)], and severe mitral annular calcification [valve- ...

Abstract	Aims: We sought to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) for patients with degenerated bioprostheses [valve-in-valve (ViV)], failed annuloplasty rings [valve-in-ring (ViR)], and severe mitral annular calcification [valve-in-mitral annular calcification (ViMAC)]. Methods and results: From the TMVR multicentre registry, procedural and clinical outcomes of ViV, ViR, and ViMAC were compared according to Mitral Valve Academic Research Consortium (MVARC) criteria. A total of 521 patients with mean Society of Thoracic Surgeons score of 9.0 ± 7.0% underwent TMVR (322 patients with ViV, 141 with ViR, and 58 with ViMAC). Trans-septal access and the Sapien valves were used in 39.5% and 90.0%, respectively. Overall technical success was excellent at 87.1%. However, left ventricular outflow tract obstruction occurred more frequently after ViMAC compared with ViR and ViV (39.7% vs. 5.0% vs. 2.2%; P < 0.001), whereas second valve implantation was more frequent in ViR compared with ViMAC and ViV (12.1% vs. 5.2% vs. 2.5%; P < 0.001). Accordingly, technical success rate was higher after ViV compared with ViR and ViMAC (94.4% vs. 80.9% vs. 62.1%; P < 0.001). Compared with ViMAC and ViV groups, ViR group had more frequent post-procedural mitral regurgitation ≥moderate (18.4% vs. 13.8% vs. 5.6%; P < 0.001) and subsequent paravalvular leak closure (7.8% vs. 0.0% vs. 2.2%; P = 0.006). All-cause mortality was higher after ViMAC compared with ViR and ViV at 30 days (34.5% vs. 9.9% vs. 6.2%; log-rank P < 0.001) and 1 year (62.8% vs. 30.6% vs. 14.0%; log-rank P < 0.001). On multivariable analysis, patients with failed annuloplasty rings and severe MAC were at increased risk of mortality after TMVR [ViR vs. ViV, hazard ratio (HR) 1.99, 95% confidence interval (CI) 1.27-3.12; P = 0.003; ViMAC vs. ViV, HR 5.29, 95% CI 3.29-8.51; P < 0.001]. Conclusion: The TMVR provided excellent outcomes for patients with degenerated bioprostheses despite high surgical risk. However, ViR and ViMAC were associated with higher rates of adverse events and mid-term mortality compared with ViV.
MeSH term(s)	Aged ; Aged, 80 and over ; Bioprosthesis ; Calcinosis/surgery ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/methods ; Humans ; Male ; Middle Aged ; Mitral Valve/pathology ; Mitral Valve/surgery ; Mitral Valve Annuloplasty/adverse effects ; Postoperative Complications/epidemiology ; Postoperative Complications/mortality ; Prosthesis Design ; Prosthesis Failure ; Stroke/etiology ; Treatment Outcome
Language	English
Publishing date	2018-10-24
Publishing country	England
Document type	Evaluation Study ; Journal Article ; Multicenter Study
ZDB-ID	603098-1
ISSN	1522-9645 ; 0195-668X
ISSN (online)	1522-9645
ISSN	0195-668X
DOI	10.1093/eurheartj/ehy590
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1563: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 640: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Atherosclerotic Vascular Disease Conference: Writing Group VI: revascularization.

Bettmann, Michael A / Dake, Michael D / Hopkins, L Nelson / Katzen, Barry T / White, Christopher J / Eisenhauer, Andrew C / Pearce, William H / Rosenfield, Kenneth A / Smalling, Richard W / Sos, Thomas A / Venbrux, Anthony C

Circulation

2004 Volume 109, Issue 21, Page(s) 2643–2650

MeSH term(s)	Angioplasty, Balloon ; Aortic Aneurysm, Abdominal/etiology ; Aortic Aneurysm, Abdominal/surgery ; Aortic Aneurysm, Thoracic/surgery ; Aortic Diseases/complications ; Aortic Diseases/surgery ; Arteriosclerosis/complications ; Arteriosclerosis/surgery ; Arteriosclerosis/therapy ; Blood Vessel Prosthesis Implantation ; Brachytherapy ; Carotid Artery Diseases/surgery ; Endarterectomy, Carotid ; Forecasting ; Humans ; Hypertension, Renovascular/etiology ; Peripheral Vascular Diseases/diagnostic imaging ; Peripheral Vascular Diseases/surgery ; Prospective Studies ; Radiography ; Randomized Controlled Trials as Topic ; Renal Artery Obstruction/complications ; Renal Artery Obstruction/surgery ; Renal Artery Obstruction/therapy ; Stents ; Vascular Surgical Procedures/methods
Language	English
Publishing date	2004-06-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	80099-5
ISSN	1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
ISSN (online)	1524-4539
ISSN	0009-7322 ; 0069-4193 ; 0065-8499
DOI	10.1161/01.CIR.0000128526.35982.9A
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui IV Zs.60: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito