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  1. Article ; Online: Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19: A retrospective cohort analysis from 28 U.S. Hospitals.

    Harthan, Aaron A / Nadiger, Meghana / McGarvey, Jeremy S / Hanson, Keith / Gharpure, Varsha P / Bjornstad, Erica C / Chiotos, Kathleen / Miller, Aaron S / Reikoff, Ronald A / Gajic, Ognjen / Kumar, Vishakha / Walkey, Allan J / Kashyap, Rahul / Tripathi, Sandeep

    Pharmacotherapy

    2022  Volume 42, Issue 7, Page(s) 529–539

    Abstract: Objectives: Suggested therapeutic options for Multisystem Inflammatory Syndrome in Children (MIS-C ... LOS) in patients with MIS-C associated with Coronavirus Disease 2019 (COVID-19).: Study design ... This was a retrospective study on 356 hospitalized patients with MIS-C from March 2020 to September 2021 ...

    Abstract Objectives: Suggested therapeutic options for Multisystem Inflammatory Syndrome in Children (MIS-C) include intravenous immunoglobulins (IVIG) and steroids. Prior studies have shown the benefit of combination therapy with both agents on fever control or the resolution of organ dysfunction. The primary objective of this study was to analyze the impact of IVIG and steroids on hospital and ICU length of stay (LOS) in patients with MIS-C associated with Coronavirus Disease 2019 (COVID-19).
    Study design: This was a retrospective study on 356 hospitalized patients with MIS-C from March 2020 to September 2021 (28 sites in the United States) in the Society of Critical Care Medicine (SCCM) Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) COVID-19 Registry. The effect of IVIG and steroids initiated in the first 2 days of admission, alone or in combination, on LOS was analyzed. Adjustment for confounders was made by multivariable mixed regression with a random intercept for the site.
    Results: The median age of the study population was 8.8 (Interquartile range (IQR) 4.0, 13) years. 247/356 (69%) patients required intensive care unit (ICU) admission during hospitalization. Overall hospital mortality was 2% (7/356). Of the total patients, 153 (43%) received IVIG and steroids, 33 (9%) received IVIG only, 43 (12%) received steroids only, and 127 (36%) received neither within 2 days of admission. After adjustment of confounders, only combination therapy showed a significant decrease of ICU LOS by 1.6 days compared to no therapy (exponentiated coefficient 0.71 [95% confidence interval 0.51, 0.97, p = 0.03]). No significant difference was observed in hospital LOS or the secondary outcome variable of the normalization of inflammatory mediators by Day 3.
    Conclusions: Combination therapy with IVIG and steroids initiated in the first 2 days of admission favorably impacts ICU but not the overall hospital LOS in children with MIS-C.
    MeSH term(s) COVID-19/complications ; COVID-19/drug therapy ; Child ; Cohort Studies ; Hospitals ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Intensive Care Units ; Length of Stay ; Retrospective Studies ; SARS-CoV-2 ; Steroids/therapeutic use ; Systemic Inflammatory Response Syndrome ; United States
    Chemical Substances Immunoglobulins, Intravenous ; Steroids
    Language English
    Publishing date 2022-06-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 603158-4
    ISSN 1875-9114 ; 0277-0008
    ISSN (online) 1875-9114
    ISSN 0277-0008
    DOI 10.1002/phar.2709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Observation of Two Excited B_{c}^{+} States and Measurement of the B_{c}^{+}(2S) Mass in pp Collisions at sqrt[s]=13  TeV.

    Sirunyan, A M / Tumasyan, A / Adam, W / Ambrogi, F / Bergauer, T / Brandstetter, J / Dragicevic, M / Erö, J / Escalante Del Valle, A / Flechl, M / Frühwirth, R / Jeitler, M / Krammer, N / Krätschmer, I / Liko, D / Madlener, T / Mikulec, I / Rad, N / Schieck, J /
    Schöfbeck, R / Spanring, M / Spitzbart, D / Waltenberger, W / Wittmann, J / Wulz, C-E / Zarucki, M / Drugakov, V / Mossolov, V / Suarez Gonzalez, J / Darwish, M R / De Wolf, E A / Di Croce, D / Janssen, X / Lauwers, J / Lelek, A / Pieters, M / Van Haevermaet, H / Van Mechelen, P / Van Remortel, N / Blekman, F / Bols, E S / Chhibra, S S / D'Hondt, J / De Clercq, J / Flouris, G / Lontkovskyi, D / Lowette, S / Marchesini, I / Moortgat, S / Moreels, L / Python, Q / Skovpen, K / Tavernier, S / Van Doninck, W / Van Mulders, P / Van Parijs, I / Beghin, D / Bilin, B / Brun, H / Clerbaux, B / De Lentdecker, G / Delannoy, H / Dorney, B / Favart, L / Grebenyuk, A / Kalsi, A K / Luetic, J / Popov, A / Postiau, N / Starling, E / Thomas, L / Vander Velde, C / Vanlaer, P / Vannerom, D / Wang, Q / Cornelis, T / Dobur, D / Fagot, A / Gul, M / Khvastunov, I / Roskas, C / Trocino, D / Tytgat, M / Verbeke, W / Vermassen, B / Vit, M / Zaganidis, N / Bondu, O / Bruno, G / Caputo, C / David, P / Delaere, C / Delcourt, M / Giammanco, A / Krintiras, G / Lemaitre, V / Magitteri, A / Piotrzkowski, K / Prisciandaro, J / Saggio, A / Vidal Marono, M / Vischia, P / Zobec, J / Alves, F L / Alves, G A / Correia Silva, G / Hensel, C / Moraes, A / Rebello Teles, P / Belchior Batista Das Chagas, E / Carvalho, W / Chinellato, J / Coelho, E / Da Costa, E M / Da Silveira, G G / De Jesus Damiao, D / Fonseca De Souza, S / Huertas Guativa, L M / Malbouisson, H / Matos Figueiredo, D / Medina Jaime, M / Melo De Almeida, M / Mora Herrera, C / Mundim, L / Nogima, H / Sanchez Rosas, L J / Santoro, A / Sznajder, A / Thiel, M / Tonelli Manganote, E J / Torres Da Silva De Araujo, F / Vilela Pereira, A / Ahuja, S / Bernardes, C A / Calligaris, L / De Souza Lemos, D / Tomei, T R Fernandez Perez / Gregores, E M / Mercadante, P G / Novaes, S F / Padula, Sandra S / Aleksandrov, A / Hadjiiska, R / Iaydjiev, P / Marinov, A / Misheva, M / Rodozov, M / Shopova, M / Sultanov, G / Dimitrov, A / Litov, L / Pavlov, B / Petkov, P / Fang, W / Gao, X / Yuan, L / Ahmad, M / Chen, G M / Chen, H S / Chen, M / Jiang, C H / Leggat, D / Liao, H / Liu, Z / Shaheen, S M / Spiezia, A / Tao, J / Yazgan, E / Zhang, H / Zhang, S / Zhao, J / Ban, Y / Chen, G / Li, J / Li, L / Li, Q / Mao, Y / Qian, S J / Wang, D / Wang, Y / Avila, C / Cabrera, A / Chaparro Sierra, L F / Florez, C / González Hernández, C F / Segura Delgado, M A / Mejia Guisao, J / Ruiz Alvarez, J D / Giljanović, D / Godinovic, N / Lelas, D / Puljak, I / Sculac, T / Antunovic, Z / Kovac, M / Brigljevic, V / Ferencek, D / Kadija, K / Mesic, B / Roguljic, M / Starodumov, A / Susa, T / Ather, M W / Attikis, A / Erodotou, E / Ioannou, A / Kolosova, M / Konstantinou, S / Mavromanolakis, G / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Tsiakkouri, D / Finger, M / Ayala, E / Carrera Jarrin, E / Assran, Y / Elgammal, S / Bhowmik, S / Carvalho Antunes De Oliveira, A / Dewanjee, R K / Ehataht, K / Kadastik, M / Raidal, M / Veelken, C / Eerola, P / Kirschenmann, H / Pekkanen, J / Voutilainen, M / Havukainen, J / Heikkilä, J K / Järvinen, T / Karimäki, V / Kinnunen, R / Lampén, T / Lassila-Perini, K / Laurila, S / Lehti, S / Lindén, T / Luukka, P / Mäenpää, T / Siikonen, H / Tuominen, E / Tuominiemi, J / Tuuva, T / Besancon, M / Couderc, F / Dejardin, M / Denegri, D / Fabbro, B / Faure, J L / Ferri, F / Ganjour, S / Givernaud, A / Gras, P / Hamel de Monchenault, G / Jarry, P / Leloup, C / Locci, E / Malcles, J / Rander, J / Rosowsky, A / Sahin, M Ö / Savoy-Navarro, A / Titov, M / Amendola, C / Beaudette, F / Busson, P / Charlot, C / Diab, B / Granier de Cassagnac, R / Kucher, I / Lobanov, A / Martin Perez, C / Nguyen, M / Ochando, C / Paganini, P / Rembser, J / Salerno, R / Sauvan, J B / Sirois, Y / Zabi, A / Zghiche, A / Agram, J-L / Andrea, J / Bloch, D / Bourgatte, G / Brom, J-M / Chabert, E C / Collard, C / Conte, E / Fontaine, J-C / Gelé, D / Goerlach, U / Jansová, M / Le Bihan, A-C / Tonon, N / Van Hove, P / Gadrat, S / Beauceron, S / Bernet, C / Boudoul, G / Camen, C / Chanon, N / Chierici, R / Contardo, D / Depasse, P / El Mamouni, H / Fay, J / Gascon, S / Gouzevitch, M / Ille, B / Lagarde, F / Laktineh, I B / Lattaud, H / Lethuillier, M / Mirabito, L / Perries, S / Sordini, V / Touquet, G / Vander Donckt, M / Viret, S / Toriashvili, T / Tsamalaidze, Z / Autermann, C / Feld, L / Kiesel, M K / Klein, K / Lipinski, M / Meuser, D / Pauls, A / Preuten, M / Rauch, M P / Schomakers, C / Teroerde, M / Wittmer, B / Albert, A / Erdmann, M / Erdweg, S / Esch, T / Fischer, B / Fischer, R / Ghosh, S / Hebbeker, T / Hoepfner, K / Keller, H / Mastrolorenzo, L / Merschmeyer, M / Meyer, A / Millet, P / Mocellin, G / Mondal, S / Mukherjee, S / Noll, D / Novak, A / Pook, T / Pozdnyakov, A / Quast, T / Radziej, M / Rath, Y / Reithler, H / Rieger, M / Schmidt, A / Schuler, S C / Sharma, A / Thüer, S / Wiedenbeck, S / Flügge, G / Hlushchenko, O / Kress, T / Müller, T / Nehrkorn, A / Nowack, A / Pistone, C / Pooth, O / Roy, D / Sert, H / Stahl, A / Aldaya Martin, M / Asawatangtrakuldee, C / Asmuss, P / Babounikau, I / Bakhshiansohi, H / Beernaert, K / Behnke, O / Behrens, U / Bermúdez Martínez, A / Bertsche, D / Bin Anuar, A A / Borras, K / Botta, V / Campbell, A / Cardini, A / Connor, P / Consuegra Rodríguez, S / Contreras-Campana, C / Danilov, V / De Wit, A / Defranchis, M M / Diez Pardos, C / Domínguez Damiani, D / Eckerlin, G / Eckstein, D / Eichhorn, T / Elwood, A / Eren, E / Gallo, E / Geiser, A / Grados Luyando, J M / Grohsjean, A / Guthoff, M / Haranko, M / Harb, A / Jomhari, N Z / Jung, H / Kasem, A / Kasemann, M / Keaveney, J / Kleinwort, C / Knolle, J / Krücker, D / Lenz, T / Leonard, J / Lidrych, J / Lipka, K / Lohmann, W / Mankel, R / Melzer-Pellmann, I-A / Meyer, A B / Meyer, M / Missiroli, M / Mittag, G / Mnich, J / Mussgiller, A / Myronenko, V / Pérez Adán, D / Pflitsch, S K / Pitzl, D / Raspereza, A / Saibel, A / Savitskyi, M / Scheurer, V / Schütze, P / Schwanenberger, C / Shevchenko, R / Singh, A / Tholen, H / Turkot, O / Vagnerini, A / Van De Klundert, M / Van Onsem, G P / Walsh, R / Wen, Y / Wichmann, K / Wissing, C / Zenaiev, O / Zlebcik, R / Aggleton, R / Bein, S / Benato, L / Benecke, A / Blobel, V / Dreyer, T / Ebrahimi, A / Fröhlich, A / Garbers, C / Garutti, E / Gonzalez, D / Gunnellini, P / Haller, J / Hinzmann, A / Karavdina, A / Kasieczka, G / Klanner, R / Kogler, R / Kovalchuk, N / Kurz, S / Kutzner, V / Lange, J / Lange, T / Malara, A / Marconi, D / Multhaup, J / Niedziela, M / Niemeyer, C E N / Nowatschin, D / Perieanu, A / Reimers, A / Rieger, O / Scharf, C / Schleper, P / Schumann, S / Schwandt, J / Sonneveld, J / Stadie, H / Steinbrück, G / Stober, F M / Stöver, M / Vormwald, B / Zoi, I / Akbiyik, M / Barth, C / Baselga, M / Baur, S / Berger, T / Butz, E / Chwalek, T / De Boer, W / Dierlamm, A / El Morabit, K / Giffels, M / Goldenzweig, P / Harrendorf, M A / Hartmann, F / Husemann, U / Kudella, S / Mitra, S / Mozer, M U / Müller, Th / Musich, M / Nürnberg, A / Quast, G / Rabbertz, K / Schröder, M / Shvetsov, I / Simonis, H J / Ulrich, R / Weber, M / Wöhrmann, C / Wolf, R / Anagnostou, G / Asenov, P / Daskalakis, G / Geralis, T / Kyriakis, A / Loukas, D / Paspalaki, G / Diamantopoulou, M / Karathanasis, G / Kontaxakis, P / Panagiotou, A / Papavergou, I / Saoulidou, N / Theofilatos, K / Vellidis, K / Bakas, G / Kousouris, K / Papakrivopoulos, I / Tsipolitis, G / Evangelou, I / Foudas, C / Gianneios, P / Katsoulis, P / Kokkas, P / Mallios, S / Manitara, K / Manthos, N / Papadopoulos, I / Paradas, E / Strologas, J / Triantis, F A / Tsitsonis, D / Bartók, M / Csanad, M / Major, P / Mandal, K / Mehta, A / Nagy, M I / Pasztor, G / Surányi, O / Veres, G I / Bencze, G / Hajdu, C / Horvath, D / Hunyadi, Á / Sikler, F / Vámi, T Á / Veszpremi, V / Vesztergombi, G / Beni, N / Czellar, S / Karancsi, J / Makovec, A / Molnar, J / Szillasi, Z / Raics, P / Teyssier, D / Trocsanyi, Z L / Ujvari, B / Choudhury, S / Komaragiri, J R / Tiwari, P C / Bahinipati, S / Kar, C / Mal, P / Muraleedharan Nair Bindhu, V K / Nayak, A / Roy Chowdhury, S / Sahoo, D K / Swain, S K / Bansal, S / Bhatnagar, V / Chauhan, S / Chawla, R / Dhingra, N / Gupta, R / Kaur, A / Kaur, M / Kaur, S / Kumari, P / Lohan, M / Meena, M / Sandeep, K / Sharma, S / Singh, J B / Virdi, A K / Walia, G / Bhardwaj, A / Choudhary, B C / Garg, R B / Gola, M / Keshri, S / Kumar, Ashok / Malhotra, S / Naimuddin, M / Priyanka, P / Ranjan, K / Shah, Aashaq / Sharma, R / Bhardwaj, R / Bharti, M / Bhattacharya, R / Bhattacharya, S / Bhawandeep, U / Bhowmik, D / Dey, S / Dutta, S / Maity, M / Mondal, K / Nandan, S / Purohit, A / Rout, P K / Roy, A / Saha, G / Sarkar, S / Sarkar, T / Sharan, M / Singh, B / Thakur, S / Behera, P K / Muhammad, A / Chudasama, R / Dutta, D / Jha, V / Kumar, V / Mishra, D K / Netrakanti, P K / Pant, L M / Shukla, P / Aziz, T / Bhat, M A / Dugad, S / Mohanty, G B / Sur, N / Kumar Verma, Ravindra / Banerjee, S / Chatterjee, S / Das, P / Guchait, M / Karmakar, S / Kumar, S / Majumder, G / Mazumdar, K / Sawant, S / Dube, S / Hegde, V / Kapoor, A / Kothekar, K / Pandey, S / Rane, A / Rastogi, A / Chenarani, S / Eskandari Tadavani, E / Etesami, S M / Khakzad, M / Mohammadi Najafabadi, M / Naseri, M / Rezaei Hosseinabadi, F / Safarzadeh, B / Felcini, M / Grunewald, M / Abbrescia, M / Calabria, C / Colaleo, A / Creanza, D / Cristella, L / De Filippis, N / De Palma, M / Di Florio, A / Fiore, L / Gelmi, A / Iaselli, G / Ince, M / Lezki, S / Maggi, G / Maggi, M / Miniello, G / My, S / Nuzzo, S / Pompili, A / Pugliese, G / Ranieri, A / Selvaggi, G / Silvestris, L / Venditti, R / Verwilligen, P / Abbiendi, G / Battilana, C / Bonacorsi, D / Borgonovi, L / Braibant-Giacomelli, S / Campanini, R / Capiluppi, P / Castro, A / Cavallo, F R / Ciocca, C / Cuffiani, M / Dallavalle, G M / Fabbri, F / Fanfani, A / Fontanesi, E / Giacomelli, P / Grandi, C / Guiducci, L / Iemmi, F / Lo Meo, S / Marcellini, S / Masetti, G / Navarria, F L / Perrotta, A / Primavera, F / Rossi, A M / Rovelli, T / Siroli, G P / Tosi, N / Albergo, S / Costa, S / Di Mattia, A / Potenza, R / Tricomi, A / Tuve, C / Barbagli, G / Ceccarelli, R / Chatterjee, K / Ciulli, V / Civinini, C / D'Alessandro, R / Focardi, E / Latino, G / Lenzi, P / Meschini, M / Paoletti, S / Russo, L / Sguazzoni, G / Strom, D / Viliani, L / Benussi, L / Bianco, S / Piccolo, D / Ferro, F / Mulargia, R / Robutti, E / Tosi, S / Benaglia, A / Beschi, A / Brivio, F / Ciriolo, V / Di Guida, S / Dinardo, M E / Dini, P / Fiorendi, S / Gennai, S / Ghezzi, A / Govoni, P / Malberti, M / Malvezzi, S / Menasce, D / Monti, F / Moroni, L / Ortona, G / Paganoni, M / Pedrini, D / Ragazzi, S / Tabarelli de Fatis, T / Zuolo, D / Buontempo, S / Cavallo, N / De Iorio, A / Di Crescenzo, A / Fabozzi, F / Fienga, F / Iorio, A O M / Lista, L / Meola, S / Paolucci, P / Rossi, B / Sciacca, C / Voevodina, E / Azzi, P / Bacchetta, N / Bisello, D / Boletti, A / Bragagnolo, A / Carlin, R / Checchia, P / Dall'Osso, M / De Castro Manzano, P / Dorigo, T / Dosselli, U / Gasparini, F / Gasparini, U / Gozzelino, A / Hoh, S Y / Lujan, P / Margoni, M / Meneguzzo, A T / Pazzini, J / Presilla, M / Ronchese, P / Rossin, R / Simonetto, F / Tiko, A / Tosi, M / Zanetti, M / Zotto, P / Zumerle, G / Braghieri, A / Montagna, P / Ratti, S P / Re, V / Ressegotti, M / Riccardi, C / Salvini, P / Vitulo, P / Biasini, M / Bilei, G M / Cecchi, C / Ciangottini, D / Fanò, L / Lariccia, P / Leonardi, R / Manoni, E / Mantovani, G / Mariani, V / Menichelli, M / Rossi, A / Santocchia, A / Spiga, D / Androsov, K / Azzurri, P / Bagliesi, G / Bertacchi, V / Bianchini, L / Boccali, T / Castaldi, R / Ciocci, M A / Dell'Orso, R / Fedi, G / Fiori, F / Giannini, L / Giassi, A / Grippo, M T / Ligabue, F / Manca, E / Mandorli, G / Messineo, A / Palla, F / Rizzi, A / Rolandi, G / Scribano, A / Spagnolo, P / Tenchini, R / Tonelli, G / Venturi, A / Verdini, P G / Cavallari, F / Cipriani, M / Del Re, D / Di Marco, E / Diemoz, M / Gelli, S / Longo, E / Marzocchi, B / Meridiani, P / Organtini, G / Pandolfi, F / Paramatti, R / Preiato, F / Quaranta, C / Rahatlou, S / Rovelli, C / Santanastasio, F / Amapane, N / Arcidiacono, R / Argiro, S / Arneodo, M / Bartosik, N / Bellan, R / Biino, C / Cappati, A / Cartiglia, N / Cenna, F / Cometti, S / Costa, M / Covarelli, R / Demaria, N / Kiani, B / Mariotti, C / Maselli, S / Migliore, E / Monaco, V / Monteil, E / Monteno, M / Obertino, M M / Pacher, L / Pastrone, N / Pelliccioni, M / Pinna Angioni, G L / Romero, A / Ruspa, M / Sacchi, R / Salvatico, R / Shchelina, K / Sola, V / Solano, A / Soldi, D / Staiano, A / Belforte, S / Candelise, V / Casarsa, M / Cossutti, F / Da Rold, A / Della Ricca, G / Vazzoler, F / Kim, B / Kim, D H / Kim, G N / Kim, M S / Lee, J / Lee, S W / Moon, C S / Oh, Y D / Pak, S I / Sekmen, S / Son, D C / Yang, Y C / Kim, H / Moon, D H / Oh, G / Francois, B / Kim, T J / Park, J / Cho, S / Choi, S / Go, Y / Gyun, D / Ha, S / Hong, B / Jo, Y / Lee, K / Lee, K S / Lee, S / Lim, J / Park, S K / Roh, Y / Goh, J / Kim, H S / Almond, J / Bhyun, J H / Choi, J / Jeon, S / Kim, J / Kim, J S / Lee, H / Nam, K / Oh, S B / Radburn-Smith, B C / Seo, S H / Yang, U K / Yoo, H D / Yoon, I / Yu, G B / Jeon, D / Kim, J H / Lee, J S H / Park, I C / Choi, Y / Hwang, C / Jeong, Y / Lee, Y / Yu, I / Veckalns, V / Dudenas, V / Juodagalvis, A / Vaitkus, J / Ibrahim, Z A / Mohamad Idris, F / Wan Abdullah, W A T / Yusli, M N / Zolkapli, Z / Benitez, J F / Castaneda Hernandez, A / Murillo Quijada, J A / Valencia Palomo, L / Castilla-Valdez, H / De La Cruz-Burelo, E / Duran-Osuna, M C / Heredia-De La Cruz, I / Lopez-Fernandez, R / Mondragon Herrera, C A / Perez Navarro, D A / Rabadan-Trejo, R I / Ramirez-Sanchez, G / Reyes-Almanza, R / Sanchez-Hernandez, A / Carrillo Moreno, S / Oropeza Barrera, C / Ramirez-Garcia, M / Vazquez Valencia, F / Eysermans, J / Pedraza, I / Salazar Ibarguen, H A / Uribe Estrada, C / Morelos Pineda, A / Raicevic, N / Krofcheck, D / Bheesette, S / Butler, P H / Ahmad, A / Hassan, Q / Hoorani, H R / Khan, W A / Shah, M A / Shoaib, M / Waqas, M / Bialkowska, H / Bluj, M / Boimska, B / Górski, M / Kazana, M / Szleper, M / Zalewski, P / Bunkowski, K / Byszuk, A / Doroba, K / Kalinowski, A / Konecki, M / Krolikowski, J / Misiura, M / Olszewski, M / Pyskir, A / Walczak, M / Araujo, M / Bargassa, P / Bastos, D / Di Francesco, A / Faccioli, P / Galinhas, B / Gallinaro, M / Hollar, J / Leonardo, N / Seixas, J / Strong, G / Toldaiev, O / Varela, J / Afanasiev, S / Bunin, P / Gavrilenko, M / Golutvin, I / Gorbunov, I / Kamenev, A / Karjavine, V / Lanev, A / Malakhov, A / Matveev, V / Moisenz, P / Palichik, V / Perelygin, V / Savina, M / Shmatov, S / Shulha, S / Skatchkov, N / Smirnov, V / Voytishin, N / Zarubin, A / Chtchipounov, L / Golovtsov, V / Ivanov, Y / Kim, V / Kuznetsova, E / Levchenko, P / Murzin, V / Oreshkin, V / Smirnov, I / Sosnov, D / Sulimov, V / Uvarov, L / Vorobyev, A / Andreev, Yu / Dermenev, A / Gninenko, S / Golubev, N / Karneyeu, A / Kirsanov, M / Krasnikov, N / Pashenkov, A / Tlisov, D / Toropin, A / Epshteyn, V / Gavrilov, V / Lychkovskaya, N / Nikitenko, A / Popov, V / Pozdnyakov, I / Safronov, G / Spiridonov, A / Stepennov, A / Toms, M / Vlasov, E / Zhokin, A / Aushev, T / Chistov, R / Danilov, M / Polikarpov, S / Tarkovskii, E / Andreev, V / Azarkin, M / Dremin, I / Kirakosyan, M / Terkulov, A / Belyaev, A / Boos, E / Dubinin, M / Dudko, L / Ershov, A / Gribushin, A / Klyukhin, V / Kodolova, O / Lokhtin, I / Obraztsov, S / Petrushanko, S / Savrin, V / Snigirev, A / Barnyakov, A / Blinov, V / Dimova, T / Kardapoltsev, L / Skovpen, Y / Azhgirey, I / Bayshev, I / Bitioukov, S / Kachanov, V / Konstantinov, D / Mandrik, P / Petrov, V / Ryutin, R / Slabospitskii, S / Sobol, A / Troshin, S / Tyurin, N / Uzunian, A / Volkov, A / Babaev, A / Iuzhakov, A / Okhotnikov, V / Ivanchenko, V / Tcherniaev, E / Adzic, P / Cirkovic, P / Devetak, D / Dordevic, M / Milenovic, P / Milosevic, J / Stojanovic, M / Aguilar-Benitez, M / Alcaraz Maestre, J / Álvarez Fernández, A / Bachiller, I / Barrio Luna, M / Brochero Cifuentes, J A / Carrillo Montoya, C A / Cepeda, M / Cerrada, M / Colino, N / De La Cruz, B / Delgado Peris, A / Fernandez Bedoya, C / Fernández Ramos, J P / Flix, J / Fouz, M C / Gonzalez Lopez, O / Goy Lopez, S / Hernandez, J M / Josa, M I / Moran, D / Navarro Tobar, Á / Pérez-Calero Yzquierdo, A / Puerta Pelayo, J / Redondo, I / Romero, L / Sánchez Navas, S / Soares, M S / Triossi, A / Willmott, C / Albajar, C / de Trocóniz, J F / Cuevas, J / Erice, C / Fernandez Menendez, J / Folgueras, S / Gonzalez Caballero, I / González Fernández, J R / Palencia Cortezon, E / Rodríguez Bouza, V / Sanchez Cruz, S / Vizan Garcia, J M / Cabrillo, I J / Calderon, A / Chazin Quero, B / Duarte Campderros, J / Fernandez, M / Fernández Manteca, P J / García Alonso, A / Gomez, G / Martinez Rivero, C / Martinez Ruiz Del Arbol, P / Matorras, F / Piedra Gomez, J / Prieels, C / Rodrigo, T / Ruiz-Jimeno, A / Scodellaro, L / Trevisani, N / Vila, I / Malagalage, K / Dharmaratna, W G D / Wickramage, N / Abbaneo, D / Akgun, B / Auffray, E / Auzinger, G / Baillon, P / Ball, A H / Barney, D / Bendavid, J / Bianco, M / Bocci, A / Botta, C / Brondolin, E / Camporesi, T / Caratelli, A / Cerminara, G / Chapon, E / Cucciati, G / d'Enterria, D / Dabrowski, A / Daci, N / Daponte, V / David, A / De Roeck, A / Deelen, N / Dobson, M / Dünser, M / Dupont, N / Elliott-Peisert, A / Fallavollita, F / Fasanella, D / Franzoni, G / Fulcher, J / Funk, W / Gigi, D / Gilbert, A / Gill, K / Glege, F / Gruchala, M / Guilbaud, M / Gulhan, D / Hegeman, J / Heidegger, C / Iiyama, Y / Innocente, V / Jafari, A / Janot, P / Karacheban, O / Kieseler, J / Krammer, M / Lange, C / Lecoq, P / Lourenço, C / Malgeri, L / Mannelli, M / Massironi, A / Meijers, F / Merlin, J A / Mersi, S / Meschi, E / Moortgat, F / Mulders, M / Ngadiuba, J / Nourbakhsh, S / Orfanelli, S / Orsini, L / Pantaleo, F / Pape, L / Perez, E / Peruzzi, M / Petrilli, A / Petrucciani, G / Pfeiffer, A / Pierini, M / Pitters, F M / Rabady, D / Racz, A / Rovere, M / Sakulin, H / Schäfer, C / Schwick, C / Selvaggi, M / Silva, P / Sphicas, P / Stakia, A / Steggemann, J / Tavolaro, V R / Treille, D / Tsirou, A / Vartak, A / Verzetti, M / Zeuner, W D / Caminada, L / Deiters, K / Erdmann, W / Horisberger, R / Ingram, Q / Kaestli, H C / Kotlinski, D / Langenegger, U / Rohe, T / Wiederkehr, S A / Backhaus, M / Berger, P / Chernyavskaya, N / Dissertori, G / Dittmar, M / Donegà, M / Dorfer, C / Gómez Espinosa, T A / Grab, C / Hits, D / Klijnsma, T / Lustermann, W / Manzoni, R A / Marionneau, M / Meinhard, M T / Micheli, F / Musella, P / Nessi-Tedaldi, F / Pauss, F / Perrin, G / Perrozzi, L / Pigazzini, S / Reichmann, M / Reissel, C / Reitenspiess, T / Ruini, D / Sanz Becerra, D A / Schönenberger, M / Shchutska, L / Vesterbacka Olsson, M L / Wallny, R / Zhu, D H / Aarrestad, T K / Amsler, C / Brzhechko, D / Canelli, M F / De Cosa, A / Del Burgo, R / Donato, S / Galloni, C / Kilminster, B / Leontsinis, S / Mikuni, V M / Neutelings, I / Rauco, G / Robmann, P / Salerno, D / Schweiger, K / Seitz, C / Takahashi, Y / Wertz, S / Zucchetta, A / Doan, T H / Kuo, C M / Lin, W / Yu, S S / Chang, P / Chao, Y / Chen, K F / Chen, P H / Hou, W-S / Li, Y Y / Lu, R-S / Paganis, E / Psallidas, A / Steen, A / Asavapibhop, B / Srimanobhas, N / Suwonjandee, N / Bat, A / Boran, F / Cerci, S / Damarseckin, S / Demiroglu, Z S / Dolek, F / Dozen, C / Dumanoglu, I / Gokbulut, G / Gurpinar Guler, Emine / Guler, Y / Hos, I / Isik, C / Kangal, E E / Kara, O / Kayis Topaksu, A / Kiminsu, U / Oglakci, M / Onengut, G / Ozdemir, K / Ozturk, S / Simsek, A E / Sunar Cerci, D / Tok, U G / Turkcapar, S / Zorbakir, I S / Zorbilmez, C / Isildak, B / Karapinar, G / Yalvac, M / Atakisi, I O / Gülmez, E / Kaya, O / Kaynak, B / Özçelik, Ö / Ozkorucuklu, S / Tekten, S / Yetkin, E A / Cakir, A / Komurcu, Y / Sen, S / Grynyov, B / Levchuk, L / Ball, F / Bhal, E / Bologna, S / Brooke, J J / Burns, D / Clement, E / Cussans, D / Davignon, O / Flacher, H / Goldstein, J / Heath, G P / Heath, H F / Kreczko, L / Paramesvaran, S / Penning, B / Sakuma, T / Seif El Nasr-Storey, S / Smith, D / Smith, V J / Taylor, J / Titterton, A / Bell, K W / Brew, C / Brown, R M / Cieri, D / Cockerill, D J A / Coughlan, J A / Harder, K / Harper, S / Linacre, J / Manolopoulos, K / Newbold, D M / Olaiya, E / Petyt, D / Reis, T / Schuh, T / Shepherd-Themistocleous, C H / Thea, A / Tomalin, I R / Williams, T / Womersley, W J / Bainbridge, R / Bloch, P / Borg, J / Breeze, S / Buchmuller, O / Bundock, A / Chahal, Gurpreet Singh / Colling, D / Dauncey, P / Davies, G / Della Negra, M / Di Maria, R / Everaerts, P / Hall, G / Iles, G / James, T / Komm, M / Laner, C / Lyons, L / Magnan, A-M / Malik, S / Martelli, A / Milosevic, V / Nash, J / Palladino, V / Pesaresi, M / Raymond, D M / Richards, A / Rose, A / Scott, E / Seez, C / Shtipliyski, A / Stoye, M / Strebler, T / Summers, S / Tapper, A / Uchida, K / Virdee, T / Wardle, N / Winterbottom, D / Wright, J / Zecchinelli, A G / Zenz, S C / Cole, J E / Hobson, P R / Khan, A / Kyberd, P / Mackay, C K / Morton, A / Reid, I D / Teodorescu, L / Zahid, S / Call, K / Dittmann, J / Hatakeyama, K / Madrid, C / McMaster, B / Pastika, N / Smith, C / Bartek, R / Dominguez, A / Uniyal, R / Buccilli, A / Cooper, S I / Henderson, C / Rumerio, P / West, C / Arcaro, D / Bose, T / Demiragli, Z / Gastler, D / Girgis, S / Pinna, D / Richardson, C / Rohlf, J / Sperka, D / Suarez, I / Sulak, L / Zou, D / Benelli, G / Burkle, B / Coubez, X / Cutts, D / Hadley, M / Hakala, J / Heintz, U / Hogan, J M / Kwok, K H M / Laird, E / Landsberg, G / Mao, Z / Narain, M / Sagir, S / Syarif, R / Usai, E / Yu, D / Band, R / Brainerd, C / Breedon, R / Calderon De La Barca Sanchez, M / Chertok, M / Conway, J / Conway, R / Cox, P T / Erbacher, R / Flores, C / Funk, G / Jensen, F / Ko, W / Kukral, O / Lander, R / Mulhearn, M / Pellett, D / Pilot, J / Shi, M / Stolp, D / Taylor, D / Tos, K / Tripathi, M / Wang, Z / Zhang, F / Bachtis, M / Bravo, C / Cousins, R / Dasgupta, A / Florent, A / Hauser, J / Ignatenko, M / Mccoll, N / Regnard, S / Saltzberg, D / Schnaible, C / Valuev, V / Burt, K / Clare, R / Gary, J W / Ghiasi Shirazi, S M A / Hanson, G / Karapostoli, G / Kennedy, E / Long, O R / Olmedo Negrete, M / Paneva, M I / Si, W / Wang, L / Wei, H / Wimpenny, S / Yates, B R / Zhang, Y / Branson, J G / Cittolin, S / Derdzinski, M / Gerosa, R / Gilbert, D / Hashemi, B / Klein, D / Krutelyov, V / Letts, J / Masciovecchio, M / May, S / Padhi, S / Pieri, M / Sharma, V / Tadel, M / Würthwein, F / Yagil, A / Zevi Della Porta, G / Amin, N / Bhandari, R / Campagnari, C / Citron, M / Dutta, V / Franco Sevilla, M / Gouskos, L / Incandela, J / Marsh, B / Mei, H / Ovcharova, A / Qu, H / Richman, J / Sarica, U / Stuart, D / Wang, S / Yoo, J / Anderson, D / Bornheim, A / Lawhorn, J M / Lu, N / Newman, H B / Nguyen, T Q / Pata, J / Spiropulu, M / Vlimant, J R / Xie, S / Zhang, Z / Zhu, R Y / Andrews, M B / Ferguson, T / Mudholkar, T / Paulini, M / Sun, M / Vorobiev, I / Weinberg, M / Cumalat, J P / Ford, W T / Johnson, A / MacDonald, E / Mulholland, T / Patel, R / Perloff, A / Stenson, K / Ulmer, K A / Wagner, S R / Alexander, J / Chaves, J / Cheng, Y / Chu, J / Datta, A / Frankenthal, A / Mcdermott, K / Mirman, N / Patterson, J R / Quach, D / Rinkevicius, A / Ryd, A / Tan, S M / Tao, Z / Thom, J / Wittich, P / Zientek, M / Abdullin, S / Albrow, M / Alyari, M / Apollinari, G / Apresyan, A / Apyan, A / Bauerdick, L A T / Beretvas, A / Berryhill, J / Bhat, P C / Burkett, K / Butler, J N / Canepa, A / Cerati, G B / Cheung, H W K / Chlebana, F / Cremonesi, M / Duarte, J / Elvira, V D / Freeman, J / Gecse, Z / Gottschalk, E / Gray, L / Green, D / Grünendahl, S / Gutsche, O / Reinsvold Hall, Allison / Hanlon, J / Harris, R M / Hasegawa, S / Heller, R / Hirschauer, J / Hu, Z / Jayatilaka, B / Jindariani, S / Johnson, M / Joshi, U / Klima, B / Kortelainen, M J / Kreis, B / Lammel, S / Lewis, J / Lincoln, D / Lipton, R / Liu, M / Liu, T / Lykken, J / Maeshima, K / Marraffino, J M / Mason, D / McBride, P / Merkel, P / Mrenna, S / Nahn, S / O'Dell, V / Papadimitriou, V / Pedro, K / Pena, C / Rakness, G / Ravera, F / Ristori, L / Schneider, B / Sexton-Kennedy, E / Smith, N / Soha, A / Spalding, W J / Spiegel, L / Stoynev, S / Strait, J / Strobbe, N / Taylor, L / Tkaczyk, S / Tran, N V / Uplegger, L / Vaandering, E W / Vernieri, C / Verzocchi, M / Vidal, R / Wang, M / Weber, H A / Acosta, D / Avery, P / Bortignon, P / Bourilkov, D / Brinkerhoff, A / Cadamuro, L / Carnes, A / Cherepanov, V / Curry, D / Errico, F / Field, R D / Gleyzer, S V / Joshi, B M / Kim, M / Konigsberg, J / Korytov, A / Lo, K H / Ma, P / Matchev, K / Menendez, N / Mitselmakher, G / Rosenzweig, D / Shi, K / Wang, J / Zuo, X / Joshi, Y R / Linn, S / Adams, T / Askew, A / Hagopian, S / Hagopian, V / Johnson, K F / Kolberg, T / Martinez, G / Prosper, H / Schiber, C / Yohay, R / Baarmand, M M / Bhopatkar, V / Hohlmann, M / Noonan, D / Rahmani, M / Saunders, M / Yumiceva, F / Adams, M R / Apanasevich, L / Berry, D / Betts, R R / Cavanaugh, R / Chen, X / Dittmer, S / Evdokimov, O / Gerber, C E / Hangal, D A / Hofman, D J / Jung, K / Mills, C / Roy, T / Tonjes, M B / Varelas, N / Wang, H / Wang, X / Wu, Z / Zhang, J / Alhusseini, M / Bilki, B / Clarida, W / Dilsiz, K / Durgut, S / Gandrajula, R P / Haytmyradov, M / Khristenko, V / Köseyan, O K / Merlo, J-P / Mestvirishvili, A / Moeller, A / Nachtman, J / Ogul, H / Onel, Y / Ozok, F / Penzo, A / Snyder, C / Tiras, E / Wetzel, J / Blumenfeld, B / Cocoros, A / Eminizer, N / Fehling, D / Feng, L / Gritsan, A V / Hung, W T / Maksimovic, P / Roskes, J / Swartz, M / Xiao, M / Baldenegro Barrera, C / Baringer, P / Bean, A / Boren, S / Bowen, J / Bylinkin, A / Isidori, T / Khalil, S / King, J / Kropivnitskaya, A / Majumder, D / Mcbrayer, W / Minafra, N / Murray, M / Rogan, C / Royon, C / Sanders, S / Schmitz, E / Tapia Takaki, J D / Williams, J / Duric, S / Ivanov, A / Kaadze, K / Kim, D / Maravin, Y / Mendis, D R / Mitchell, T / Mohammadi, A / Rebassoo, F / Wright, D / Baden, A / Baron, O / Belloni, A / Eno, S C / Feng, Y / Ferraioli, C / Hadley, N J / Jabeen, S / Jeng, G Y / Kellogg, R G / Kunkle, J / Mignerey, A C / Nabili, S / Ricci-Tam, F / Seidel, M / Shin, Y H / Skuja, A / Tonwar, S C / Wong, K / Abercrombie, D / Allen, B / Baty, A / Bi, R / Brandt, S / Busza, W / Cali, I A / D'Alfonso, M / Gomez Ceballos, G / Goncharov, M / Harris, P / Hsu, D / Hu, M / Klute, M / Kovalskyi, D / Lee, Y-J / Luckey, P D / Maier, B / Marini, A C / Mcginn, C / Mironov, C / Narayanan, S / Niu, X / Paus, C / Rankin, D / Roland, C / Roland, G / Shi, Z / Stephans, G S F / Sumorok, K / Tatar, K / Velicanu, D / Wang, T W / Wyslouch, B / Benvenuti, A C / Chatterjee, R M / Evans, A / Hansen, P / Hiltbrand, J / Kalafut, S / Kubota, Y / Lesko, Z / Mans, J / Rusack, R / Wadud, M A / Acosta, J G / Oliveros, S / Avdeeva, E / Bloom, K / Claes, D R / Fangmeier, C / Finco, L / Golf, F / Gonzalez Suarez, R / Kamalieddin, R / Kravchenko, I / Siado, J E / Snow, G R / Stieger, B / Godshalk, A / Harrington, C / Iashvili, I / Kharchilava, A / Mclean, C / Nguyen, D / Parker, A / Rappoccio, S / Roozbahani, B / Alverson, G / Barberis, E / Freer, C / Haddad, Y / Hortiangtham, A / Madigan, G / Morse, D M / Orimoto, T / Skinnari, L / Tishelman-Charny, A / Wamorkar, T / Wang, B / Wisecarver, A / Wood, D / Bueghly, J / Gunter, T / Hahn, K A / Schmitt, M H / Sung, K / Trovato, M / Velasco, M / Bucci, R / Dev, N / Goldouzian, R / Hildreth, M / Hurtado Anampa, K / Jessop, C / Karmgard, D J / Lannon, K / Li, W / Loukas, N / Marinelli, N / Mcalister, I / Meng, F / Mueller, C / Musienko, Y / Planer, M / Ruchti, R / Siddireddy, P / Smith, G / Taroni, S / Wayne, M / Wightman, A / Wolf, M / Woodard, A / Alimena, J / Bylsma, B / Durkin, L S / Flowers, S / Francis, B / Hill, C / Ji, W / Lefeld, A / Ling, T Y / Winer, B L / Cooperstein, S / Dezoort, G / Elmer, P / Haubrich, N / Higginbotham, S / Kalogeropoulos, A / Kwan, S / Lange, D / Lucchini, M T / Luo, J / Marlow, D / Mei, K / Ojalvo, I / Olsen, J / Palmer, C / Piroué, P / Salfeld-Nebgen, J / Stickland, D / Tully, C / Norberg, S / Barker, A / Barnes, V E / Das, S / Gutay, L / Jones, M / Jung, A W / Khatiwada, A / Mahakud, B / Miller, D H / Negro, G / Neumeister, N / Peng, C C / Piperov, S / Qiu, H / Schulte, J F / Sun, J / Wang, F / Xiao, R / Xie, W / Cheng, T / Dolen, J / Parashar, N / Ecklund, K M / Freed, S / Geurts, F J M / Kilpatrick, M / Kumar, Arun / Padley, B P / Redjimi, R / Roberts, J / Rorie, J / Shi, W / Stahl Leiton, A G / Tu, Z / Zhang, A / Bodek, A / de Barbaro, P / Demina, R / Duh, Y T / Dulemba, J L / Fallon, C / Ferbel, T / Galanti, M / Garcia-Bellido, A / Han, J / Hindrichs, O / Khukhunaishvili, A / Ranken, E / Tan, P / Taus, R / Chiarito, B / Chou, J P / Gershtein, Y / Halkiadakis, E / Hart, A / Heindl, M / Hughes, E / Kaplan, S / Kyriacou, S / Laflotte, I / Lath, A / Montalvo, R / Nash, K / Osherson, M / Saka, H / Salur, S / Schnetzer, S / Sheffield, D / Somalwar, S / Stone, R / Thomas, S / Thomassen, P / Acharya, H / Delannoy, A G / Heideman, J / Riley, G / Spanier, S / Bouhali, O / Celik, A / Dalchenko, M / De Mattia, M / Delgado, A / Dildick, S / Eusebi, R / Gilmore, J / Huang, T / Kamon, T / Luo, S / Marley, D / Mueller, R / Overton, D / Perniè, L / Rathjens, D / Safonov, A / Akchurin, N / Damgov, J / De Guio, F / Kunori, S / Lamichhane, K / Mengke, T / Muthumuni, S / Peltola, T / Undleeb, S / Volobouev, I / Whitbeck, A / Greene, S / Gurrola, A / Janjam, R / Johns, W / Maguire, C / Ni, H / Romeo, F / Sheldon, P / Tuo, S / Velkovska, J / Verweij, M / Arenton, M W / Barria, P / Cox, B / Cummings, G / Hirosky, R / Joyce, M / Ledovskoy, A / Neu, C / Tannenwald, B / Wolfe, E / Xia, F / Harr, R / Karchin, P E / Poudyal, N / Sturdy, J / Thapa, P / Zaleski, S / Buchanan, J / Caillol, C / Carlsmith, D / Dasu, S / De Bruyn, I / Dodd, L / Gomber, B / Grothe, M / Herndon, M / Hervé, A / Hussain, U / Klabbers, P / Lanaro, A / Long, K / Loveless, R / Ruggles, T / Savin, A / Smith, W H / Woods, N

    Physical review letters

    2019  Volume 122, Issue 13, Page(s) 132001

    Abstract: Signals consistent with the B_{c}^{+}(2S) and B_{c}^{*+}(2S) states are observed in proton-proton ... collisions at sqrt[s]=13  TeV, in an event sample corresponding to an integrated luminosity of 143  fb^{-1 ... collected by the CMS experiment during the 2015-2018 LHC running periods. These excited b[over ¯]c states ...

    Abstract Signals consistent with the B_{c}^{+}(2S) and B_{c}^{*+}(2S) states are observed in proton-proton collisions at sqrt[s]=13  TeV, in an event sample corresponding to an integrated luminosity of 143  fb^{-1}, collected by the CMS experiment during the 2015-2018 LHC running periods. These excited b[over ¯]c states are observed in the B_{c}^{+}π^{+}π^{-} invariant mass spectrum, with the ground state B_{c}^{+} reconstructed through its decay to J/ψπ^{+}. The two states are reconstructed as two well-resolved peaks, separated in mass by 29.1±1.5(stat)±0.7(syst)  MeV. The observation of two peaks, rather than one, is established with a significance exceeding five standard deviations. The mass of the B_{c}^{+}(2S) meson is measured to be 6871.0±1.2(stat)±0.8(syst)±0.8(B_{c}^{+})  MeV, where the last term corresponds to the uncertainty in the world-average B_{c}^{+} mass.
    Language English
    Publishing date 2019-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.122.132001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Estadt, Angela T / Miller, William C / Kline, David / Whitney, Bridget M / Young, April M / Todd Korthuis, P / Stopka, Thomas J / Feinberg, Judith / Zule, William A / Pho, Mai T / Friedmann, Peter D / Westergaard, Ryan P / Eagen, Kellene V / Seaman, Andrew / Ma, Jimmy / Go, Vivian F / Lancaster, Kathryn E

    The International journal on drug policy

    2023  , Page(s) 104222

    Abstract: Background: People who inject drugs (PWID) in the rural U.S. often inject stimulants, alone or ... in ten U.S. states from 2018 to 2020. This cross-sectional analysis included adult participants ...

    Abstract Background: People who inject drugs (PWID) in the rural U.S. often inject stimulants, alone or with opioids. The impact of these substance use patterns may influence HCV risk behaviors. This analysis examines the associations of HCV antibody positivity with injecting only opioids, only stimulants (methamphetamine/cocaine), and opioids and stimulants together among rural PWID.
    Methods: The Rural Opioid Initiative (ROI) consists of eight research sites that enrolled people who use drugs in rural communities in ten U.S. states from 2018 to 2020. This cross-sectional analysis included adult participants who resided in a study area and injected any drug in the past 30 days. The primary outcome was HCV antibody positivity. The exposure of interest was injection drug use classified as only opioids, only stimulants, separate injections of opioids and stimulants, and same-syringe injection of both in the past 30 days. We used multivariable log-binomial regression with generalized linear mixed models to generate prevalence ratios (P.R.) adjusted for demographics, injection history, health insurance, and substance use treatment.
    Results: Among 3,084 participants enrolled in the ROI, 1,982 met inclusion criteria. Most participants injected opioids and stimulants in the same syringe (34%) or separately (21%), followed by injecting only stimulants (26%), and injecting only opioids (19%). Half (51%) were HCV antibody positive. Compared to people who injected only stimulants, HCV antibody positivity was more prevalent among people who injected opioids alone (aPR=1.62, 95% CI:(1.29-2.03)), injected both opioids and stimulants separately (aPR=1.61, 95% CI:(1.32-1.95)), and in the same syringe (aPR=1.54, 95% CI:(1.28-1.85)).
    Conclusion: HCV antibody positivity, indicating prior exposure, was highest among those who had recently injected opioids, alone or with stimulants. Additional nucleic acid testing is necessary to confirm active infection. More research is needed to determine the underlying causes of HCV antibody positivity by injection use.
    Language English
    Publishing date 2023-10-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2010000-0
    ISSN 1873-4758 ; 0955-3959
    ISSN (online) 1873-4758
    ISSN 0955-3959
    DOI 10.1016/j.drugpo.2023.104222
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  4. Article ; Online: GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease

    Lauren M. McIntyre / Francisco Huertas / Alison M. Morse / Rachel Kaletsky / Coleen T. Murphy / Vrinda Kalia / Gary W. Miller / Olexander Moskalenko / Ana Conesa / Danielle E. Mor

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 9

    Abstract: Abstract Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell ... molecular targets. C. elegans is a genetically tractable model system that can be used to disentangle ... the integrative analysis of gene expression and metabolite levels of a C. elegans PD model using GAIT-GM, a new ...

    Abstract Abstract Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood, limiting the development of therapies directed at disease-relevant molecular targets. C. elegans is a genetically tractable model system that can be used to disentangle disease mechanisms in complex diseases such as PD. Such mechanisms can be studied combining high-throughput molecular profiling technologies such as transcriptomics and metabolomics. However, the integrative analysis of multi-omics data in order to unravel disease mechanisms is a challenging task without advanced bioinformatics training. Galaxy, a widely-used resource for enabling bioinformatics analysis by the broad scientific community, has poor representation of multi-omics integration pipelines. We present the integrative analysis of gene expression and metabolite levels of a C. elegans PD model using GAIT-GM, a new Galaxy tool for multi-omics data analysis. Using GAIT-GM, we discovered an association between branched-chain amino acid metabolism and cholinergic neurons in the C. elegans PD model. An independent follow-up experiment uncovered cholinergic neurodegeneration in the C. elegans model that is consistent with cholinergic cell loss observed in PD. GAIT-GM is an easy to use Galaxy-based tool for generating novel testable hypotheses of disease mechanisms involving gene-metabolite relationships.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Stereoretentive C(sp³)–S Cross-Coupling

    Zhu, Feng / Eric Miller / Shuo-qing Zhang / Duk Yi / Sloane O’Neill / Xin Hong / Maciej A. Walczak

    Journal of the American Chemical Society. 2018 Nov. 26, v. 140, no. 51

    2018  

    Abstract: We report a stereoretentive cross-coupling reaction of configurationally stable nucleophiles with disulfide and N-sulfenylsuccinimide donors promoted by Cu(I). We demonstrate the utility of this method in the synthesis of thioglycosides derived from ... ...

    Abstract We report a stereoretentive cross-coupling reaction of configurationally stable nucleophiles with disulfide and N-sulfenylsuccinimide donors promoted by Cu(I). We demonstrate the utility of this method in the synthesis of thioglycosides derived from simple alkyl and aryl thiols, thioglycosides, and in the glycodiversification of cysteine residues in peptides. These reactions operate well with carbohydrate substrates containing common protective groups and reagents with free hydroxyl and secondary amide functionalities under standardized conditions. Competition experiments in combination with computational DFT studies established that the putative anomeric intermediate is an organocopper species that is configurationally stable and resistant to epimerization due to its short lifetime. The subsequent reductive elimination from the Cu(III) intermediate is rapid and stereoretentive. Taken together, the glycosyl cross-coupling is ideally suited for late stage glycodiversification and bioconjugation under highly controlled installation of the aliphatic carbon–sulfur bonds.
    Keywords Lewis bases ; carbohydrates ; chemical bonding ; copper ; cross-coupling reactions ; cysteine ; peptides ; thiols
    Language English
    Dates of publication 2018-1126
    Size p. 18140-18150.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.8b11211
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  6. Article ; Online: Biostimulation induces syntrophic interactions that impact C, S and N cycling in a sediment microbial community.

    Handley, Kim M / VerBerkmoes, Nathan C / Steefel, Carl I / Williams, Kenneth H / Sharon, Itai / Miller, Christopher S / Frischkorn, Kyle R / Chourey, Karuna / Thomas, Brian C / Shah, Manesh B / Long, Philip E / Hettich, Robert L / Banfield, Jillian F

    The ISME journal

    2012  Volume 7, Issue 4, Page(s) 800–816

    Abstract: Stimulation of subsurface microorganisms to induce reductive immobilization of metals is a promising approach for bioremediation, yet the overall microbial community response is typically poorly understood. Here we used proteogenomics to test the ... ...

    Abstract Stimulation of subsurface microorganisms to induce reductive immobilization of metals is a promising approach for bioremediation, yet the overall microbial community response is typically poorly understood. Here we used proteogenomics to test the hypothesis that excess input of acetate activates complex community functioning and syntrophic interactions among autotrophs and heterotrophs. A flow-through sediment column was incubated in a groundwater well of an acetate-amended aquifer and recovered during microbial sulfate reduction. De novo reconstruction of community sequences yielded near-complete genomes of Desulfobacter (Deltaproteobacteria), Sulfurovum- and Sulfurimonas-like Epsilonproteobacteria and Bacteroidetes. Partial genomes were obtained for Clostridiales (Firmicutes) and Desulfuromonadales-like Deltaproteobacteria. The majority of proteins identified by mass spectrometry corresponded to Desulfobacter-like species, and demonstrate the role of this organism in sulfate reduction (Dsr and APS), nitrogen fixation and acetate oxidation to CO2 during amendment. Results indicate less abundant Desulfuromonadales, and possibly Bacteroidetes, also actively contributed to CO2 production via the tricarboxylic acid (TCA) cycle. Proteomic data indicate that sulfide was partially re-oxidized by Epsilonproteobacteria through nitrate-dependent sulfide oxidation (using Nap, Nir, Nos, SQR and Sox), with CO2 fixed using the reverse TCA cycle. We infer that high acetate concentrations, aimed at stimulating anaerobic heterotrophy, led to the co-enrichment of, and carbon fixation in Epsilonproteobacteria. Results give an insight into ecosystem behavior following addition of simple organic carbon to the subsurface, and demonstrate a range of biological processes and community interactions were stimulated.
    MeSH term(s) Bacteroidetes/classification ; Bacteroidetes/isolation & purification ; Bacteroidetes/metabolism ; Biodegradation, Environmental ; Carbon ; Deltaproteobacteria/classification ; Deltaproteobacteria/isolation & purification ; Deltaproteobacteria/metabolism ; Ecosystem ; Epsilonproteobacteria/classification ; Epsilonproteobacteria/isolation & purification ; Epsilonproteobacteria/metabolism ; Fresh Water/microbiology ; Geologic Sediments/microbiology ; Groundwater/microbiology ; Nitrogen Cycle ; Oxidation-Reduction ; Proteomics ; Sulfur
    Chemical Substances Sulfur (70FD1KFU70) ; Carbon (7440-44-0)
    Language English
    Publishing date 2012-11-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2406536-5
    ISSN 1751-7370 ; 1751-7362
    ISSN (online) 1751-7370
    ISSN 1751-7362
    DOI 10.1038/ismej.2012.148
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  7. Article: Mathematical simulation of the diel O, S, and C biogeochemistry of a hypersaline microbial mat.

    Decker, K L M / Potter, C S / Bebout, B M / Marais, D J Des / Carpenter, S / Discipulo, M / Hoehler, T M / Miller, S R / Thamdrup, B / Turk, K A / Visscher, P T

    FEMS microbiology ecology

    2005  Volume 52, Issue 3, Page(s) 377–395

    Abstract: The creation of a mathematical simulation model of photosynthetic microbial mats is important to our understanding of key biogeochemical cycles that may have altered the atmospheres and lithospheres of early Earth. A model is presented here as a tool to ... ...

    Abstract The creation of a mathematical simulation model of photosynthetic microbial mats is important to our understanding of key biogeochemical cycles that may have altered the atmospheres and lithospheres of early Earth. A model is presented here as a tool to integrate empirical results from research on hypersaline mats from Baja California Sur (BCS), Mexico into a computational system that can be used to simulate biospheric inputs of trace gases to the atmosphere. The first version of our model, presented here, calculates fluxes and cycling of O(2), sulfide, and dissolved inorganic carbon (DIC) via abiotic components and via four major microbial guilds: cyanobacteria (CYA), sulfate reducing bacteria (SRB), purple sulfur bacteria (PSB) and colorless sulfur bacteria (CSB). We used generalized Monod-type equations that incorporate substrate and energy limits upon maximum rates of metabolic processes such as photosynthesis and sulfate reduction. We ran a simulation using temperature and irradiance inputs from data collected from a microbial mat in Guerrero Negro in BCS (Mexico). Model O(2), sulfide, and DIC concentration profiles and fluxes compared well with data collected in the field mats. There were some model-predicted features of biogeochemical cycling not observed in our actual measurements. For instance, large influxes and effluxes of DIC across the MBGC mat boundary may reveal previously unrecognized, but real, in situ limits on rates of biogeochemical processes. Some of the short-term variation in field-collected mat O(2) was not predicted by MBGC. This suggests a need both for more model sensitivity to small environmental fluctuations for the incorporation of a photorespiration function into the model.
    MeSH term(s) Carbon/metabolism ; Chromatiaceae/growth & development ; Chromatiaceae/metabolism ; Cyanobacteria/growth & development ; Cyanobacteria/metabolism ; Darkness ; Ecosystem ; Geologic Sediments/chemistry ; Geologic Sediments/microbiology ; Inorganic Chemicals/metabolism ; Light ; Models, Biological ; Oxygen/metabolism ; Photosynthesis ; Sodium Chloride ; Sulfides/metabolism ; Sulfur-Reducing Bacteria/growth & development ; Sulfur-Reducing Bacteria/metabolism
    Chemical Substances Inorganic Chemicals ; Sulfides ; Sodium Chloride (451W47IQ8X) ; Carbon (7440-44-0) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2005-05-01
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 283722-5
    ISSN 1574-6941 ; 0168-6496
    ISSN (online) 1574-6941
    ISSN 0168-6496
    DOI 10.1016/j.femsec.2004.12.005
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  8. Article: Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

    Antal, Corina E / Andrew M. Hudson / Emily Kang / Ciro Zanca / Christopher Wirth / Natalie L. Stephenson / Eleanor W. Trotter / Lisa L. Gallegos / Crispin J. Miller / Frank B. Furnari / Tony Hunter / John Brognard / Alexandra C. Newton

    Cell. 2015 Jan. 29, v. 160

    2015  

    Abstract: Protein kinase C (PKC) isozymes have remained elusive cancer targets despite the unambiguous tumor ...

    Abstract Protein kinase C (PKC) isozymes have remained elusive cancer targets despite the unambiguous tumor promoting function of their potent ligands, phorbol esters, and the prevalence of their mutations. We analyzed 8% of PKC mutations identified in human cancers and found that, surprisingly, most were loss of function and none were activating. Loss-of-function mutations occurred in all PKC subgroups and impeded second-messenger binding, phosphorylation, or catalysis. Correction of a loss-of-function PKCβ mutation by CRISPR-mediated genome editing in a patient-derived colon cancer cell line suppressed anchorage-independent growth and reduced tumor growth in a xenograft model. Hemizygous deletion promoted anchorage-independent growth, revealing that PKCβ is haploinsufficient for tumor suppression. Several mutations were dominant negative, suppressing global PKC signaling output, and bioinformatic analysis suggested that PKC mutations cooperate with co-occurring mutations in cancer drivers. These data establish that PKC isozymes generally function as tumor suppressors, indicating that therapies should focus on restoring, not inhibiting, PKC activity.
    Keywords bioinformatics ; catalytic activity ; colorectal neoplasms ; esters ; genome ; humans ; isozymes ; ligands ; loss-of-function mutation ; models ; phosphorylation ; protein kinase C
    Language English
    Dates of publication 2015-0129
    Size p. 489-502.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2015.01.001
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  9. Article ; Online: Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: modulation by interferon-β and role played in cell migration.

    Staun-Ram, Elsebeth / Miller, Ariel

    Journal of neuroimmunology

    2011  Volume 232, Issue 1-2, Page(s) 200–206

    Abstract: We investigated the modulation of Cathepsin S, Cathepsin B and Cystatin C expression ... of Cathepsin S in T cells, while increased Cystatin C. Neutralizing Cystatin C increased cell migration ... while migration of monocytes and T cells was inhibited by IFN-β, by Cystatin C, and T cell migration was ...

    Abstract We investigated the modulation of Cathepsin S, Cathepsin B and Cystatin C expression in immune cells by interferon (IFN)-β, and their role in cell migration. Cathepsin levels were increased in monocytic and T line cells upon activation. IFN-β abolished this increase of Cathepsin B in monocytes and of Cathepsin S in T cells, while increased Cystatin C. Neutralizing Cystatin C increased cell migration, while migration of monocytes and T cells was inhibited by IFN-β, by Cystatin C, and T cell migration was suppressed by Cathepsin S and B inhibitors. These findings support further studies in the importance of Cathepsins and Cystatins in immunomodulation.
    MeSH term(s) Blotting, Western ; Cathepsin B/immunology ; Cathepsin B/metabolism ; Cathepsins/immunology ; Cathepsins/metabolism ; Cell Movement ; Chemotaxis, Leukocyte/physiology ; Cystatin C/immunology ; Cystatin C/metabolism ; Humans ; Interferon-beta/immunology ; Interferon-beta/metabolism ; Jurkat Cells ; Monocytes/cytology ; Monocytes/immunology ; Monocytes/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; U937 Cells
    Chemical Substances CST3 protein, human ; Cystatin C ; Interferon-beta (77238-31-4) ; Cathepsins (EC 3.4.-) ; CTSB protein, human (EC 3.4.22.1) ; Cathepsin B (EC 3.4.22.1) ; cathepsin S (EC 3.4.22.27)
    Language English
    Publishing date 2011-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 8335-5
    ISSN 1872-8421 ; 0165-5728
    ISSN (online) 1872-8421
    ISSN 0165-5728
    DOI 10.1016/j.jneuroim.2010.10.015
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  10. Article: Application of the S(2infinity) and C(infinity) point groups for the prediction of polymer chirality.

    Miller, Stephen A

    Chemical communications (Cambridge, England)

    2006  , Issue 8, Page(s) 862–864

    Abstract: ... C(infinity) molecular point groups to infinite cyclic polymers, obviating the usual dependence ...

    Abstract Polymer chirality assignment is achieved with the first chemical applications of the S2infinity and C(infinity) molecular point groups to infinite cyclic polymers, obviating the usual dependence on translational symmetry operations.
    Language English
    Publishing date 2006-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/b516276a
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