LIVIVO - Search results -

Search results

Result 1 - 10 of total 173

Search options

Article: Supplementation of green coffee bean extract in healthy overweight subjects increases lean mass/fat mass ratio: A randomized, double-blind clinical study.

Sudeep, H V / Shyam Prasad, K

2021 Volume 9, Page(s) 20503121211002590

Abstract: Objective: In this study, we have demonstrated that supplementation of a complex of chlorogenic acid isomers (CGA-7: Method: In a double-blind, placebo-controlled clinical study, healthy overweight (body mass index ⩾ 25 to <30 kg/m: Results: Sixty ...

Abstract	Objective: In this study, we have demonstrated that supplementation of a complex of chlorogenic acid isomers (CGA-7 Method: In a double-blind, placebo-controlled clinical study, healthy overweight (body mass index ⩾ 25 to <30 kg/m Results: Sixty subjects completed the study. Mean body weight and body mass index were significantly reduced in CGA-7 group as compared to placebo ( Conclusion: To conclude, this study provides scientific validation of the functionality of green coffee bean extract and recommends the safety of the supplementation in healthy individuals.
Language	English
Publishing date	2021-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2735399-0
ISSN	2050-3121
ISSN	2050-3121
DOI	10.1177/20503121211002590
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.

Sudeep, H V / Thomas, Jestin V / Shyamprasad, K

BMC urology

2020 Volume 20, Issue 1, Page(s) 86

Abstract: Background: The present clinical trial was conducted to evaluate the efficacy and tolerability of a standardized saw palmetto oil containing 3% β-sitosterol in the treatment of benign prostate hyperplasia (BPH) and androgen deficiency.: Methods: ... ...

Abstract	Background: The present clinical trial was conducted to evaluate the efficacy and tolerability of a standardized saw palmetto oil containing 3% β-sitosterol in the treatment of benign prostate hyperplasia (BPH) and androgen deficiency. Methods: Subjects aged 40-65 years with symptomatic BPH were randomized to 12-week double-blind treatment with 500 mg doses of β-sitosterol enriched saw palmetto oil, conventional saw palmetto oil and placebo orally in the form of capsules (n = 33 in each group). BPH severity was determined using the International Prostate Symptom Score (IPSS), uroflowmetry, serum measurement of prostate specific antigen (PSA), testosterone and 5α-reductase. During the trial, the androgen deficiency was evaluated using Aging Male Symptoms (AMS) scale, the Androgen Deficiency in the Aging Male (ADAM) questionnaire, serum levels of free testosterone. Results: Subjects treated with β-sitosterol enriched saw palmetto oil showed significant decrease in IPSS, AMS and ADAM scores along with reduced postvoiding residual volume (p < 0.001), PSA (p < 0.01) and 5α-reductase from baseline to end of 12-week treatment as compared to placebo. There was also a significant increment in the maximum and average urine flow rate (p < 0.001), and serum free testosterone level of subjects treated with enriched saw palmetto oil as compared to placebo. Conclusion: This study demonstrates the efficacy of β-sitosterol enriched saw palmetto oil superior to conventional oil thus extending the scope of effective BPH and androgen deficiency treatment with improved quality of life through the intake of functional ingredients. Trial registration: CTRI/2018/12/016724 dated 19/12/2018 prospectively registered. URL: http://ctri.nic.in/Clinicaltrials/advsearch.php.
MeSH term(s)	Adult ; Aged ; Androgens/deficiency ; Double-Blind Method ; Humans ; Male ; Middle Aged ; Phytosterols/therapeutic use ; Phytotherapy ; Plant Extracts/therapeutic use ; Plant Oils/therapeutic use ; Prostatic Hyperplasia/drug therapy ; Sitosterols/therapeutic use ; Treatment Outcome ; Urological Agents/therapeutic use
Chemical Substances	Androgens ; Phytosterols ; Plant Extracts ; Plant Oils ; Sitosterols ; Urological Agents ; gamma-sitosterol (5LI01C78DD) ; saw palmetto extract (J7WWH9M8QS)
Language	English
Publishing date	2020-07-03
Publishing country	England
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial
ZDB-ID	2059857-9
ISSN	1471-2490 ; 1471-2490
ISSN (online)	1471-2490
ISSN	1471-2490
DOI	10.1186/s12894-020-00648-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Molecular docking analysis of Withaferin A from Withania somnifera with the Glucose regulated protein 78 (GRP78) receptor and the SARS-CoV-2 main protease.

Sudeep, H V / Gouthamchandra, K / Shyamprasad, K

Bioinformation

2020 Volume 16, Issue 5, Page(s) 411–417

Abstract: Design and development of an effective compound to combat COVID-19 is clearly critical in the current circumstances. Therefore, it is of interest to document the molecular docking analysis data of the cellular receptor Glucose regulated protein 78 (GRP78) ...

Abstract	Design and development of an effective compound to combat COVID-19 is clearly critical in the current circumstances. Therefore, it is of interest to document the molecular docking analysis data of the cellular receptor Glucose regulated protein 78 (GRP78) with Withaferin A from Withania somnifera in the context of COVID-19 pandemic for further consideration. Here, we report the optimal interaction features of withaferin A, artemisinin, curcumin and andrographolide with the GRP78 receptor having low binding energies (-8.7, -7.89, -6.21 and -6.17 kcal/mol respectively) in this report. In order to gain additional insights, the interaction pattern of compounds with SARS-CoV-2 main protease (Mpro) was studied.
Keywords	covid19
Language	English
Publishing date	2020-04-30
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/97320630016411
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: A standardized black pepper seed extract containing β‐caryophyllene improves cognitive function in scopolamine‐induced amnesia model mice via regulation of brain‐derived neurotrophic factor and MAPK proteins

Sudeep, H. V. / Venkatakrishna, K. / Amritharaj / Gouthamchandra, K. / Reethi, B. / Naveen, P. / Lingaraju, H. B. / Shyamprasad, K.

Journal of food biochemistry. 2021 Dec., v. 45, no. 12

2021

Abstract: β‐caryophyllene (BCP), a natural sesquiterpene present in plants, is a selective agonist of cannabinoid receptor type‐2 (CB2) of the endocannabinoid system. In this study, we have prepared an extract from Piper nigrum (black pepper) seeds using ... ...

Abstract	β‐caryophyllene (BCP), a natural sesquiterpene present in plants, is a selective agonist of cannabinoid receptor type‐2 (CB2) of the endocannabinoid system. In this study, we have prepared an extract from Piper nigrum (black pepper) seeds using supercritical fluid extraction, standardized to contain 30% BCP (Viphyllinᵀᴹ). The beneficial effects of prophylactic treatment with Viphyllin on cognitive functions were demonstrated in Scopolamine‐induced dementia model mice. Male Swiss albino mice (25–30 g) were administered with Viphyllin (50 mg and 100 mg/kg body weight p.o.) or donepezil (1.60 mg/kg) for 14 days. Subsequently, cognitive deficits were induced by treating the animals intraperitoneally with Scopolamine (0.75 mg/kg). The cognitive behavior of mice was evaluated using a novel object recognition test (NORT) and Morris water maze (MWM) test. The brain homogenates were studied for biochemical parameters including cholinesterase activities and antioxidant status. Western blot analysis was performed to investigate the mechanism of action. Viphyllin dose dependently improved the recognition and spatial memory and cholinergic functions in Scop‐treated mice. The extract was found protective against Scop‐induced oxidative damage and histopathologic changes in the brain. At 100 mg/kg Viphyllin markedly reduced the proBDNF/mBDNF ratio (p < .05) and augmented the TrkB expression (p < .01). Viphyllin (100 mg/kg) was found to be neuroprotective by reducing the Scop‐induced upregulation of p‐JNK and p‐p38 MAPK proteins, Bax/Bcl‐2 ratio, and caspase activation in the brain. Viphyllin also exerted anti‐inflammatory effects by downregulating Cox‐2, TNF‐α, and NOS‐2 in Scop‐induced mice (p < .05). To summarize, our data encourage Viphyllin as a functional ingredient/dietary supplement for brain health and cognition. PRACTICAL APPLICATIONS: Black pepper is a culinary spice having several medicinal attributes. Essential oils in the seeds of the plant give aroma and flavor to it. Here we have prepared an extract from the seeds of black pepper using supercritical fluid extraction, characterized for the presence of β‐caryophyllene (not <30%). This research work further validates the neuroprotective mechanism of the extract in Scopolamine‐induced cognitive impairment model mice. The findings from this study strongly suggest the beneficial neuroactive properties of black pepper seed extract having the presence of BCP, a CB2 receptor agonist. It can thus be used potentially as a functional food ingredient for cognition and brain function.
Keywords	Piper nigrum ; Western blotting ; agonists ; albino ; amnesia ; antioxidants ; black pepper ; body weight ; brain ; cannabinoid receptors ; cannabinoids ; caspases ; cholinesterase ; cognition ; cognitive disorders ; dementia ; dietary supplements ; disease prevention ; flavor ; food composition ; functional foods ; histopathology ; ingredients ; males ; mechanism of action ; odors ; scopolamine ; seed extracts ; spatial memory ; supercritical fluid extraction
Language	English
Dates of publication	2021-12
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	433846-7
ISSN	1745-4514 ; 0145-8884
ISSN (online)	1745-4514
ISSN	0145-8884
DOI	10.1111/jfbc.13994
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 3310: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Molecular docking analysis of Withaferin A from Withania somnifera with the Glucose regulated protein 78 (GRP78) receptor and the SARS-CoV-2 main protease

Sudeep, H V / Gouthamchandra, K / Shyamprasad, K

Bioinformation

Abstract	Design and development of an effective compound to combat COVID-19 is clearly critical in the current circumstances. Therefore, it is of interest to document the molecular docking analysis data of the cellular receptor Glucose regulated protein 78 (GRP78) with Withaferin A from Withania somnifera in the context of COVID-19 pandemic for further consideration. Here, we report the optimal interaction features of withaferin A, artemisinin, curcumin and andrographolide with the GRP78 receptor having low binding energies (-8.7, -7.89, -6.21 and -6.17 kcal/mol respectively) in this report. In order to gain additional insights, the interaction pattern of compounds with SARS-CoV-2 main protease (Mpro) was studied.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #729743
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: A standardized black pepper seed extract containing β-caryophyllene improves cognitive function in scopolamine-induced amnesia model mice via regulation of brain-derived neurotrophic factor and MAPK proteins.

Sudeep, H V / Venkatakrishna, K / Amritharaj / Gouthamchandra, K / Reethi, B / Naveen, P / Lingaraju, H B / Shyamprasad, K

Journal of food biochemistry

2021 Volume 45, Issue 12, Page(s) e13994

Abstract: β-caryophyllene (BCP), a natural sesquiterpene present in plants, is a selective agonist of cannabinoid receptor type-2 (CB2) of the endocannabinoid system. In this study, we have prepared an extract from Piper nigrum (black pepper) seeds using ... ...

Abstract	β-caryophyllene (BCP), a natural sesquiterpene present in plants, is a selective agonist of cannabinoid receptor type-2 (CB2) of the endocannabinoid system. In this study, we have prepared an extract from Piper nigrum (black pepper) seeds using supercritical fluid extraction, standardized to contain 30% BCP (Viphyllin
MeSH term(s)	Amnesia/chemically induced ; Amnesia/drug therapy ; Animals ; Brain-Derived Neurotrophic Factor ; Cognition ; Male ; Mice ; Piper nigrum ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Polycyclic Sesquiterpenes ; Scopolamine/toxicity
Chemical Substances	Brain-Derived Neurotrophic Factor ; Plant Extracts ; Polycyclic Sesquiterpenes ; caryophyllene (BHW853AU9H) ; Scopolamine (DL48G20X8X)
Language	English
Publishing date	2021-11-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	433846-7
ISSN	1745-4514 ; 0145-8884
ISSN (online)	1745-4514
ISSN	0145-8884
DOI	10.1111/jfbc.13994
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 3310: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: Viwithan, a Standardized

Sudeep, H V / Gouthamchandra, K / Venkatesh, B J / Prasad, K Shyam

Pharmacognosy magazine

2018 Volume 13, Issue Suppl 4, Page(s) S801–S806

Abstract: ... highly effective against B16F1 cells with an IC50 value of 220 μg/ml after 24 h treatment ...

Abstract	Background: Withania somnifera Objective: In the present study, we have evaluated the antiproliferative activity of a standardized Materials and methods: The cytotoxicity of Viwithan was determined using thiazolyl blue tetrazolium blue assay and crystal violet staining. The apoptotic changes in B16F1 cells following treatment with Viwithan were observed by acridine orange/ethidium bromide (AO/EB) staining and DNA fragmentation assay. The binding affinity of withanolides in Viwithan with antiapoptotic proteins B-cell lymphoma 2, B-cell lymphoma-extra large, and myeloid cell leukemia 1 (MCL-1) were studied using Results: The half maximal inhibitory concentration (IC50) values of Viwithan against liver hepatocellular carcinoma, Henrietta Lacks cervical carcinoma cells, human colorectal carcinoma cell line, and Ehrlich ascites carcinoma cells were 1830, 968, 2715, and 633 μg/ml, respectively. Interestingly, Viwithan was highly effective against B16F1 cells with an IC50 value of 220 μg/ml after 24 h treatment. The morphological alterations of apoptotic cell death were clearly observed in the AO/EB-stained cells after treatment with Viwithan. Viwithan induced late apoptotic changes in treated B16F1 cells as evident by the ladder formation of fragmented DNA in a time-dependent manner. The findings of molecular docking showed that withanolides present in Viwithan have a more binding affinity with the antiapoptotic proteins, particularly MCL-1. Conclusion: We have reported for the first time that Viwithan with 5% withanolides has a potent cytotoxic effect, particularly against B16F1 murine melanoma cells among the different cancer cell lines tested. Summary: The present study reports for the first time that Viwithan, a standardized 5%
Language	English
Publishing date	2018-01-31
Publishing country	India
Document type	Journal Article
ZDB-ID	2274976-7
ISSN	0976-4062 ; 0973-1296
ISSN (online)	0976-4062
ISSN	0973-1296
DOI	10.4103/pm.pm_121_17
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Essential oil of Lippia alba impedes the growth of Propionibacterium acnes by modulating membrane potential and ROS level

Uma Kumari, KM / Chanotiya, Chandan Singh / Yadav, Narayan Prasad / Tandon, Sudeep / Luqman, Suaib

Journal of Herbal Medicine. 2023 Aug. 08, p.100733-

2023 , Page(s) 100733–

Abstract: ... 125% v/v, and the MIC of Mentha, Ocimum, and Patchouli oils ranged from 0.25 to 0.50% v/v. Further ... at MIC till 12 h and at 2 × MIC until 72 h. Moreover, the oils induced ROS production with one fold ...

Abstract	Propionibacterium acnes (P. acnes) is a rod-shaped, anaerobic, Gram-positive, opportunistic bacterium, that causes infectious and inflammatory diseases, such as acne vulgaris synovitis-acnes-pustulosis-hyperostosis-osteitis syndrome, sarcoidosis, and prostate cancer. Earlier evidence suggests that essential oils have been used to treat skin diseases and disorders since ancient times. Thus, the present study investigated the anti-microbial activity of 28 essential oils from nine families, including Lamiaceae, Poaceae, Geraniaceae, Myrtaceae, Zingiberaceae, Verbenaceae, Cupressaceae, Asteraceae, and Cyperaceae against P. acnes. The anti-bacterial susceptibility and efficacy of the essential oils were examined using paper disc diffusion, broth micro-dilution, time-kill kinetics and ROS assays. P. acnes was cultured under anaerobic conditions. The kinetic process evaluated the time and dose-dependent effects of essential oils. The alteration in membrane potential and ROS production were measured in terms of mean fluorescence intensity. Consequently, the chemical composition of essential oil was analyzed by GC and GC/MS analysis. Eighteen essential oils inhibited the growth of P. acnes with a clear zone of 5 to 20.33 mm. Eucalyptus, Mentha, Palmarosa, Lemongrass, Citronella, Geranium, Patchouli, Ocimum, and Clarysage possess better antibacterial activity (ZGI: 10.33 ± 2.31 mm - 20.33 ± 4.72 mm). Lippia oil showed the minimum inhibitory concentration (MIC) of 0.125% v/v, and the MIC of Mentha, Ocimum, and Patchouli oils ranged from 0.25 to 0.50% v/v. Further, the concentration and time-kill kinetic study indicated that Lippia alba and O. sanctum oils suppress the growth at MIC till 12 h and at 2 × MIC until 72 h. Moreover, the oils induced ROS production with one fold change at 2 × MIC. In addition, O. sanctum oil altered the membrane integrity with a fold change of 1.0 and 2.0 at MIC and 2 × MIC, respectively, while L. alba oil modified a fold change of 1.0. The essential oils suppressed bacterial growth by inducing ROS and modulating membrane integrity. Therefore, L. alba and O. sanctum essential oils could be used as an alternative to chemicals/drugs for treating microbe-associated acne problems.
Keywords	Asteraceae ; Citronella ; Cupressaceae ; Cymbopogon ; Cyperaceae ; Eucalyptus ; Geranium ; Lippia alba ; Mentha ; Ocimum ; Pogostemon cablin ; Propionibacterium ; Zingiberaceae ; acne ; antibacterial properties ; bacteria ; bacterial growth ; chemical composition ; dose response ; essential oils ; fluorescence ; herbal medicines ; membrane potential ; minimum inhibitory concentration ; oils ; paper ; prostatic neoplasms ; BHIB ; BHIA ; °C ; CFU/mL ; DCF ; DCFDA ; DMSO ; h ; μM ; µg/mL ; mg/mL ; MBC ; MIC ; MIF ; MP ; nm ; OD ; % ; P. acnes ; ROS ; US$ ; v/v ; ZGI ; Anti-bacterial susceptibility ; O. sanctum
Language	English
Dates of publication	2023-0808
Publishing place	Elsevier GmbH
Document type	Article ; Online
Note	Pre-press version
ISSN	2210-8033
DOI	10.1016/j.hermed.2023.100733
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.

Advani, Jayshree / Mehta, Puja A / Hamel, Andrew R / Mehrotra, Sudeep / Kiel, Christina / Strunz, Tobias / Corso-Díaz, Ximena / Kwicklis, Madeline / van Asten, Freekje / Ratnapriya, Rinki / Chew, Emily Y / Hernandez, Dena G / Montezuma, Sandra R / Ferrington, Deborah A / Weber, Bernhard H F / Segrè, Ayellet V / Swaroop, Anand

Nature communications

2024 Volume 15, Issue 1, Page(s) 1972

Abstract: DNA methylation provides a crucial epigenetic mark linking genetic variations to environmental influence. We have analyzed array-based DNA methylation profiles of 160 human retinas with co-measured RNA-seq and >8 million genetic variants, uncovering ... ...

Abstract	DNA methylation provides a crucial epigenetic mark linking genetic variations to environmental influence. We have analyzed array-based DNA methylation profiles of 160 human retinas with co-measured RNA-seq and >8 million genetic variants, uncovering sites of genetic regulation in cis (37,453 methylation quantitative trait loci and 12,505 expression quantitative trait loci) and 13,747 DNA methylation loci affecting gene expression, with over one-third specific to the retina. Methylation and expression quantitative trait loci show non-random distribution and enrichment of biological processes related to synapse, mitochondria, and catabolism. Summary data-based Mendelian randomization and colocalization analyses identify 87 target genes where methylation and gene-expression changes likely mediate the genotype effect on age-related macular degeneration. Integrated pathway analysis reveals epigenetic regulation of immune response and metabolism including the glutathione pathway and glycolysis. Our study thus defines key roles of genetic variations driving methylation changes, prioritizes epigenetic control of gene expression, and suggests frameworks for regulation of macular degeneration pathology by genotype-environment interaction in retina.
MeSH term(s)	Humans ; DNA Methylation/genetics ; Epigenesis, Genetic ; Epigenome ; Macular Degeneration/genetics ; Retina
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-46063-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Unravelling the synthetic and therapeutic aspects of five, six and fused heterocycles using Vilsmeier-Haack reagent.

Chahal, Mamta / Dhillon, Sudeep / Rani, Priyanka / Kumari, Ginna / Aneja, Deepak Kumar / Kinger, Mayank

RSC advances

2023 Volume 13, Issue 38, Page(s) 26604–26629

Abstract: ... range of heterocyclic compounds using the Vilsmeier-Haack (V. H.) reagent. These derivatives act ... of a variety of heterocyclic scaffolds. The V. H. reagent, a versatile reagent in organic chemistry, is used ... efficacy, and potency of V. H. reagents, plenty of heterocyclic compounds can be synthesized which serve ...

Abstract	The aim of this review is to encapsulate the synthetic protocols and medicinal aspects of a wide range of heterocyclic compounds using the Vilsmeier-Haack (V. H.) reagent. These derivatives act as excellent precursors having different aryl ring functionalities and could be used for the synthesis of a variety of heterocyclic scaffolds. The V. H. reagent, a versatile reagent in organic chemistry, is used to formylate various heterocyclic compounds of medicinal interest. Due to the different chemical interactions, efficacy, and potency of V. H. reagents, plenty of heterocyclic compounds can be synthesized which serve as a constituent in various novel medications and acts as a bridge between biology and chemistry. These carboxylate moieties can effectively cooperate as precursors for several multi-component reactions (MCR) including Strecker synthesis, Bucherer-Berg reaction and post-MCR cyclization, modified variants with various pharmaceutical applications such as anti-tumor, anti-convulsant, anti-chitosomal and so on.
Language	English
Publishing date	2023-09-05
Publishing country	England
Document type	Journal Article ; Review
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra04309f
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED