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  1. Article ; Online: Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging.

    Nayak, Pratuysha / Bag, Janmejaya / Padhan, Subrata Kumar / Sahoo, Harekrushna / Sahu, Satya Narayan / Mishra, Monalisa

    Chemical research in toxicology

    2023  Volume 36, Issue 6, Page(s) 926–933

    Abstract: ... ...

    Abstract Drosophila
    MeSH term(s) Humans ; Animals ; Drosophila melanogaster/genetics ; Actins ; Fluorescent Dyes/pharmacology ; Coumarins/pharmacology ; Larva
    Chemical Substances Actins ; Fluorescent Dyes ; Coumarins
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639353-6
    ISSN 1520-5010 ; 0893-228X
    ISSN (online) 1520-5010
    ISSN 0893-228X
    DOI 10.1021/acs.chemrestox.3c00051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2320: Show issues Location:
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  2. Article ; Online: Nanomaterial catalyzed green synthesis of tetrazoles and its derivatives: a review on recent advancements.

    Swami, Suman / Sahu, Satya Narayan / Shrivastava, Rahul

    RSC advances

    2021  Volume 11, Issue 62, Page(s) 39058–39086

    Abstract: Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, ... ...

    Abstract Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, pharmacology
    Language English
    Publishing date 2021-12-07
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d1ra05955f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Butterfly pea (Clitoria ternatea) extract as a green analytical tool for selective colorimetric detection of bisulphate (HSO

    Rana, Punam / Murmu, Narayan / Padhan, Subrata Kumar / Sahu, Satya Narayan

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2020  Volume 237, Page(s) 118376

    Abstract: The blue color of butterfly pea (Clitoria ternatea) was extracted by Milli-Q water and evaluated for selective detection of bisulphate ( ... ...

    Abstract The blue color of butterfly pea (Clitoria ternatea) was extracted by Milli-Q water and evaluated for selective detection of bisulphate (HSO
    MeSH term(s) Anions/analysis ; Clitoria/chemistry ; Color ; Colorimetry/methods ; Green Chemistry Technology ; Metals/chemistry ; Plant Extracts/chemistry ; Solubility ; Solvents/chemistry ; Spectrometry, Fluorescence ; Spectrophotometry, Ultraviolet ; Sulfates/analysis ; Water/chemistry
    Chemical Substances Anions ; Metals ; Plant Extracts ; Solvents ; Sulfates ; Water (059QF0KO0R)
    Language English
    Publishing date 2020-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2020.118376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  4. Article ; Online: Computational study to evaluate the potency of phytochemicals in

    Sahu, Satya Narayan / Satpathy, Sneha Shriparna / Mohanty, Chandana / Pattanayak, Subrat Kumar

    Journal of biomolecular structure & dynamics

    2021  Volume 40, Issue 18, Page(s) 8587–8601

    Abstract: A protein's function is closely related to its structural properties. Mutations can affect the functionality of a protein. Different cancer tissues have found disordered expression of the cyclin-dependent kinase 2-associated Protein 1 (CDK2AP1) gene. A ... ...

    Abstract A protein's function is closely related to its structural properties. Mutations can affect the functionality of a protein. Different cancer tissues have found disordered expression of the cyclin-dependent kinase 2-associated Protein 1 (CDK2AP1) gene. A protein molecule's conformational flexibility affects its interaction with phytochemicals and their biological partners at various levels.
    MeSH term(s) Cyclin-Dependent Kinase 2/genetics ; Molecular Docking Simulation ; Mutant Proteins ; Nyctaginaceae/chemistry ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Point Mutation
    Chemical Substances Mutant Proteins ; Phytochemicals ; Plant Extracts ; Cyclin-Dependent Kinase 2 (EC 2.7.11.22)
    Language English
    Publishing date 2021-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2021.1914169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article: Improvements in

    Halder, Kumaresh / Sahu, Jatindra Kumar / Naik, Satya Narayan / Mandal, Surajit / Bag, Subrata Kumar

    Journal of food science and technology

    2020  Volume 58, Issue 5, Page(s) 1640–1654

    Abstract: Since Vedic times, traditional Indian cultured butter ... ...

    Abstract Since Vedic times, traditional Indian cultured butter or
    Language English
    Publishing date 2020-08-20
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 242498-8
    ISSN 0975-8402 ; 0022-1155
    ISSN (online) 0975-8402
    ISSN 0022-1155
    DOI 10.1007/s13197-020-04711-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Bonn / Germany

    Z 2636: Show issues

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  6. Article ; Online: Synthesis of First Coumarin Fluorescent Dye for Actin Visualization.

    Padhan, Subrata Kumar / Bag, Janmejaya / Panda, Munmun / Biswal, Bijesh Kumar / Sahoo, Harekrushna / Mishra, Monalisa / Sahu, Satya Narayan

    Bioconjugate chemistry

    2022  Volume 33, Issue 11, Page(s) 2113–2120

    Abstract: Selective fluorescence imaging of actin protein hugely depends on the fluorescently labeled actin-binding domain (ABD). Thus, it is always a challenging task to image the actin protein ( ...

    Abstract Selective fluorescence imaging of actin protein hugely depends on the fluorescently labeled actin-binding domain (ABD). Thus, it is always a challenging task to image the actin protein (
    MeSH term(s) Animals ; Actins/metabolism ; Fluorescent Dyes/chemistry ; Drosophila melanogaster ; Coumarins/chemistry ; Cell Line
    Chemical Substances Actins ; Fluorescent Dyes ; Coumarins
    Language English
    Publishing date 2022-10-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1024041-x
    ISSN 1520-4812 ; 1043-1802
    ISSN (online) 1520-4812
    ISSN 1043-1802
    DOI 10.1021/acs.bioconjchem.2c00332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3400: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: Nanomaterial catalyzed green synthesis of tetrazoles and its derivatives: a review on recent advancements

    Swami, Suman / Sahu, Satya Narayan / Shrivastava, Rahul

    RSC advances. 2021 Dec. 07, v. 11, no. 62

    2021  

    Abstract: Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, pharmacology etc. Owing to their useful ... ...

    Abstract Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, pharmacology etc. Owing to their useful applications, a wide range of catalysts have been explored for green synthesis of tetrazole derivatives. In recent times, nanomaterials have been emerged as extremely efficient catalysts for different organic transformations because of their high surface area-to-volume ratio, easy surface modification, simple fabrications, easy recovery and reusability. In this article, we have presented an overview of utilization of various nano-catalysts, nanocomposites and other solid-supported nanomaterials as an efficient environmental benign catalytic system for green synthesis of tetrazoles and derivatives. This review will provide an exclusive emphasis on boehmite, magnetic, copper, carbon, MCM-41, and composite based nanomaterials that have been developed since the year 2010 for the synthesis of tetrazole derivatives. In addition, we have briefly discussed the fabrication, functionalization and characterization of some novel nanomaterials and their advantages in the synthesis of tetrazole and its derivatives along with the reaction mechanism that involves synthesis of tetrazole derivatives via nanomaterials catalysed reactions.
    Keywords biochemistry ; boehmite ; carbon ; catalytic activity ; copper ; energy ; heterocyclic compounds ; magnetism ; nanocatalysts ; nanocomposites ; nitrogen ; pharmacology ; reaction mechanisms
    Language English
    Dates of publication 2021-1207
    Size p. 39058-39086.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d1ra05955f
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Through bond energy transfer (TBET)-operated fluoride ion sensing

    Padhan, Subrata Kumar / Mishra, Vipin Kumar / Murmu, Narayan / Mishra, Sabyashachi / Sahu, Satya Narayan

    RSC advances

    2020  Volume 10, Issue 47, Page(s) 28422–28430

    Abstract: The detection of fluoride ions in a competitive environment often poses several challenges. In this work, we have designed and synthesized a coumarin functionalized fluorescein dyad (R3) which represents an ideal through bond energy transfer (TBET) ... ...

    Abstract The detection of fluoride ions in a competitive environment often poses several challenges. In this work, we have designed and synthesized a coumarin functionalized fluorescein dyad (R3) which represents an ideal through bond energy transfer (TBET) fluorophore with the coumarin unit as donor and fluorescein unit as acceptor. The bichromophoric dyad demonstrates the detection of fluoride ions in the parts per billion (ppb) concentration level (22.8 ppb) with high selectivity
    Language English
    Publishing date 2020-07-30
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d0ra05357k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Utility of Epicardial Fat Thickness in Subclinical Hypothyroid Children to Determine Existence of Subclinical Atherosclerosis in Them.

    Sahu, Madhusmita / Mishra, Ipsita / Baliarsinha, Anoj Kumar / Choudhury, Arun Kumar / Routray, Satya Narayan

    Indian journal of endocrinology and metabolism

    2022  Volume 26, Issue 5, Page(s) 483–489

    Abstract: Context: Adult studies have shown the association of subclinical hypothyroid (SCH) with various cardiovascular dysfunction, which indicates SCH may be a potentially modifiable risk factor of CV disease and mortality. However, there is still controversy ... ...

    Abstract Context: Adult studies have shown the association of subclinical hypothyroid (SCH) with various cardiovascular dysfunction, which indicates SCH may be a potentially modifiable risk factor of CV disease and mortality. However, there is still controversy about the association of cardiovascular dysfunction in children with SCH. Epicardial fat thickness (EFT) is a reliable and sensitive marker of cardiovascular risk and has become an emerging modality to predict CV risks.
    Aims: To measure the EFT in children with subclinical hypothyroidism and compare with healthy children. To find its correlation with subclinical atherosclerosis. To compare EFT between TPO positive and TPO negative subclinical hypothyroid patients.
    Materials and methods: Children of subclinical hypothyroidism (TSH >5 mIU/ml with normal FT3, FT4, and age and sex matched control were included as per inclusion and exclusion criteria. Clinical data was collected from all study subjects. Thyroid function tests including FT3, FT4 and TSH, TPO antibody, fasting insulin, hsCRP, Lp(a), USG neck for carotid intima media thickness (CIMT), USG brachial artery for flow mediated dilation (FMD) and echocardiography for epicardial fat thickness (EFT) were done in all patients.
    Results: A total 42 number of SCH and 50 age and sex matched controls were recruited and screened for various parameters of subclinical atherosclerosis. EFT was significantly higher in the cases than in the controls (6.27 mm vs 4.54 mm) with
    Conclusion: Results of this study show the presence of subclinical atherosclerosis in children with SCH regardless of the aetiologies. The patients of Hashimoto thyroiditis had significantly high insulin resistance and inflammation than the SCH patients of other aetiologies.
    Language English
    Publishing date 2022-11-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2600211-5
    ISSN 2230-9500 ; 2230-8210
    ISSN (online) 2230-9500
    ISSN 2230-8210
    DOI 10.4103/ijem.ijem_296_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Molecular dynamics simulation perception study of the binding affinity performance for main protease of SARS-CoV-2.

    Sahu, Satya Narayan / Mishra, Biswajit / Sahu, Rojalin / Pattanayak, Subrat Kumar

    Journal of biomolecular structure & dynamics

    2020  Volume 40, Issue 6, Page(s) 2444–2459

    Abstract: Like common cold and flu, SARC-CoV-2 virus spreads by droplets of sneezes or coughs which virus affects people of various age groups. Today, this virus is almost distributed all over the world. Since binding process plays a crucial role between host and ... ...

    Abstract Like common cold and flu, SARC-CoV-2 virus spreads by droplets of sneezes or coughs which virus affects people of various age groups. Today, this virus is almost distributed all over the world. Since binding process plays a crucial role between host and receptor, therefore, we studied the molecules intended toward inhibition process through molecular docking and molecular dynamics simulation process. From the molecular docking study, it is noteworthy that remdesivir shows better binding affinity toward the main protease of SARS-CoV2 compared to other studied drugs. Within studied phytochemicals, carnosic acid shows better binding poses toward main protease of SARS-CoV2 among studied phytochemicals. The amino acid residues GLN110 and PHE294 were almost found in all the studied interactions of drugs and phytochemicals with main protease of SARS-CoV-2. Furthermore, the results show a larger contribution of the Van der Waals energies as compared to others like electrostatic energies suggesting that ligands at the binding pocket are predominantly stabilized by hydrophobic interactions. The conformational change during ligand binding was predicted from Gibbs free energy landscape analysis through molecular dynamics simulation. We observed that, there were two main free energy basins for both docked carnosic acid complex and for docked remdesivir complex, only one main free energy basin was found in the global free energy minimum region.Communicated by Ramaswamy H. Sarma.
    MeSH term(s) COVID-19/drug therapy ; Coronavirus 3C Proteases/metabolism ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; SARS-CoV-2
    Chemical Substances 3C-like proteinase, SARS-CoV-2 (EC 3.4.22.-) ; Coronavirus 3C Proteases (EC 3.4.22.28)
    Language English
    Publishing date 2020-11-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2020.1850362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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