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Book ; Thesis: Classification of the level of mandibular atrophy - a computer-assisted study based on 500 CT scans

Varga, Viktoria Alegra

2018

Author's details	vorgelegt von Viktoria Alegra Varga
Language	English
Size	[7] Seiten, Illustrationen
Publishing place	Aachen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Dissertation, RWTH Aachen University, 2018
Note	Die Dissertation wurde zuvor 2017 in der Zeitschrift "Journal of Cranio-Maxillo-Facial Surgery" (45.2017:2061-2067) veröffentlicht
HBZ-ID	HT019761536
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Acetyl group for proper protection of β-sugar-amino acids used in SPPS.

Varga, István / Goldschmidt Gőz, Viktória / Pintér, István / Csámpai, Antal / Perczel, András

Amino acids

2023 Volume 55, Issue 8, Page(s) 969–979

Abstract: The synthesis of D-glucosamine-1-carboxylic acid based β-sugar amino acids (β-SAAs) is typically performed in nine consecutive steps via an inefficient OAc → Br → CN conversion protocol with low overall yield. Here, we present the improved and more ... ...

Abstract	The synthesis of D-glucosamine-1-carboxylic acid based β-sugar amino acids (β-SAAs) is typically performed in nine consecutive steps via an inefficient OAc → Br → CN conversion protocol with low overall yield. Here, we present the improved and more efficient synthesis of both Fmoc-GlcAPC-OH and Fmoc-GlcAPC(Ac)-OH, β-SAAs consisting of only 4-5 synthetic steps. Their active ester and amide bond formation with glycine methyl ester (H-Gly-OMe) was completed and monitored by
MeSH term(s)	Amino Acids/chemistry ; Sugars ; Peptides/chemistry ; Carbohydrates ; Fluorenes/chemistry
Chemical Substances	Amino Acids ; Sugars ; stable plasma protein solution ; Peptides ; Carbohydrates ; Fluorenes
Language	English
Publishing date	2023-06-21
Publishing country	Austria
Document type	Journal Article
ZDB-ID	1121341-3
ISSN	1438-2199 ; 0939-4451
ISSN (online)	1438-2199
ISSN	0939-4451
DOI	10.1007/s00726-023-03278-1
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Article ; Online: Water-Insoluble, Thermostable, Crosslinked Gelatin Matrix for Soft Tissue Implant Development.

Varga, Viktória / Smeller, László / Várdai, Róbert / Kocsis, Bence / Zsoldos, Ibolya / Cruciani, Sara / Pala, Renzo / Hornyák, István

International journal of molecular sciences

2024 Volume 25, Issue 8

Abstract: In this present study, the material science background of crosslinked gelatin (GEL) was investigated. The aim was to assess the optimal reaction parameters for the production of a water-insoluble crosslinked gelatin matrix suitable for heat sterilization. ...

Abstract	In this present study, the material science background of crosslinked gelatin (GEL) was investigated. The aim was to assess the optimal reaction parameters for the production of a water-insoluble crosslinked gelatin matrix suitable for heat sterilization. Matrices were subjected to enzymatic degradation assessments, and their ability to withstand heat sterilization was evaluated. The impact of different crosslinkers on matrix properties was analyzed. It was found that matrices crosslinked with butanediol diglycidyl ether (BDDE) and poly(ethylene glycol) diglycidyl ether (PEGDE) were resistant to enzymatic degradation and heat sterilization. Additionally, at 1
MeSH term(s)	Gelatin/chemistry ; Cross-Linking Reagents/chemistry ; Water/chemistry ; Polyethylene Glycols/chemistry ; Hot Temperature ; Tissue Scaffolds/chemistry ; Biocompatible Materials/chemistry ; Materials Testing ; Spectroscopy, Fourier Transform Infrared ; Solubility ; Sterilization/methods ; Epoxy Resins
Chemical Substances	Gelatin (9000-70-8) ; Cross-Linking Reagents ; Water (059QF0KO0R) ; Polyethylene Glycols (3WJQ0SDW1A) ; Biocompatible Materials ; Quetol 651 (29317-04-2) ; Epoxy Resins
Language	English
Publishing date	2024-04-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25084336
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Article ; Online: Daganatos nőbetegek termékenységének megőrzése.

Vesztergom, Dóra / Nánássy, László / Polgár, Csaba / Krádi, Anna / Rosta, Viktória / Varga, Szilvia / Novák, Zoltán

Orvosi hetilap

2023 Volume 164, Issue 28, Page(s) 1094–1101

Abstract: The incidence of cancer increases with age and as family planning is being delayed, there is a growing number of cancer patients whose fertility may be affected by oncological treatments. International guidelines recommend that all reproductive age ... ...

Title translation	Fertility preservation in female cancer patients.
Abstract	The incidence of cancer increases with age and as family planning is being delayed, there is a growing number of cancer patients whose fertility may be affected by oncological treatments. International guidelines recommend that all reproductive age cancer patients, including adolescent patients, should be referred for fertility preservation consultation, and if necessary, fertility preservation procedures should be performed. Fertility preservation enables cancer survivors to offer a chance for biological parenthood after recovery. In this review, the gonadotoxic effects of oncological therapies and the fertility preservation possibilities for female cancer patients based on international recommendations and literature are discussed. Our next review will provide detailed information on the special fertility preservation possibilities for different cancer types. The two reviews may help to elaborate a national guidance. Orv Hetil. 2023; 164(28): 1094-1101.
MeSH term(s)	Adolescent ; Humans ; Female ; Fertility Preservation/methods ; Cryopreservation/methods ; Neoplasms/complications ; Neoplasms/therapy ; Fertility ; Reproduction
Language	Hungarian
Publishing date	2023-07-16
Publishing country	Hungary
Document type	Review ; English Abstract ; Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2023.32823
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Article: Radiation of mushroom-forming fungi correlates with novel modes of protecting sexual fruiting bodies.

Varga, Torda / Földi, Csenge / Bense, Viktória / Nagy, László G

Fungal biology

2022 Volume 126, Issue 9, Page(s) 556–565

Abstract: The protection of vulnerable developing structures evolved repeatedly in terrestrial organisms and includes, among others, viviparity in animals and the seed in land plants. In mushroom-forming fungi (Agaricomycetes), sexual spores are born on fruiting ... ...

Abstract	The protection of vulnerable developing structures evolved repeatedly in terrestrial organisms and includes, among others, viviparity in animals and the seed in land plants. In mushroom-forming fungi (Agaricomycetes), sexual spores are born on fruiting bodies, the growth of which is a complex developmental process that is exposed to environmental factors (e.g., desiccation, fungivorous animals). Mushroom-forming fungi evolved a series of innovations in fruiting body protection, however, how these emerged is obscure, leaving the evolutionary principles of fruiting body development poorly known. Here, we show that developmental innovations that lead to the spore-producing surface (hymenophore) being enclosed in a protected environment display asymmetry in their evolution and are associated with increased diversification rates. 'Enclosed' development evolved convergently and became a dominant developmental type in several clades of mushrooms. This probably mirrors spore production benefits for species with protected fruiting body initials, by better coping with environmental factors. Our observations highlight new morphological traits associated with mushroom diversification that parallel the evolution of protection strategies in other organisms, such as viviparity or the seed in animals or plants, respectively, but in the context of spore development, highlighting the general importance of protecting vulnerable progeny across the tree of life.
MeSH term(s)	Agaricales ; Ascomycota ; Basidiomycota ; Fruiting Bodies, Fungal
Language	English
Publishing date	2022-07-16
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2532164-X
ISSN	1878-6162 ; 1878-6146
ISSN (online)	1878-6162
ISSN	1878-6146
DOI	10.1016/j.funbio.2022.07.001
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Article ; Online: Assessment of amino-terminal C-type natriuretic peptide serum level and its correlation with high-density lipoprotein structure and function in patients with end stage renal disease before and after kidney transplantation.

Szentimrei, Réka / Lőrincz, Hajnalka / Szentpéteri, Anita / Varga, Viktória Evelin / Seres, Ildikó / Varga, Éva / Nemes, Balázs / Harangi, Mariann / Paragh, György

Chemico-biological interactions

2023 Volume 385, Page(s) 110749

Abstract: We aimed to investigate serum amino-terminal C-type natriuretic peptide (NT-proCNP) and its relationship with quantitative and qualitative HDL-parameters in patients with end-stage renal disease (ESRD) before, then 1 and 6 months after kidney ... ...

Abstract	We aimed to investigate serum amino-terminal C-type natriuretic peptide (NT-proCNP) and its relationship with quantitative and qualitative HDL-parameters in patients with end-stage renal disease (ESRD) before, then 1 and 6 months after kidney transplantation (TX). Seventy patients (47 males, 23 females, mean age 51.7 ± 12.4 years) were enrolled in a prospective follow-up study. We examined serum creatinine, C-reactive protein, procalcitonin, fasting glucose and lipid parameters before, then 1 and 6 months after TX. High-density lipoprotein- (HDL)-associated paraoxonase-1 (PON1) paraoxonase and arylesterase activities were measured spectrophotometrically. Lipoprotein subfractions were determined by Lipoprint. NT-proCNP and oxidized low-density lipoprotein (oxLDL) levels were measured by ELISA. Mean NT-proCNP was 45.8 ± 21.9 pmol/L before renal transplantation and decreased markedly 1 month and 6 months after transplantation (5.3 ± 2.5 and 7.7 ± 4.9 pmol/L, respectively, P = 1 × 10
MeSH term(s)	Male ; Female ; Humans ; Adult ; Middle Aged ; Natriuretic Peptide, C-Type ; Lipoproteins, HDL ; Kidney Transplantation ; Follow-Up Studies ; Prospective Studies ; Procalcitonin ; Aryldialkylphosphatase/metabolism ; Creatinine ; Kidney Failure, Chronic/surgery ; Vasodilator Agents ; Cholesterol
Chemical Substances	Natriuretic Peptide, C-Type (127869-51-6) ; Lipoproteins, HDL ; Procalcitonin ; Aryldialkylphosphatase (EC 3.1.8.1) ; Creatinine (AYI8EX34EU) ; Vasodilator Agents ; Cholesterol (97C5T2UQ7J) ; PON1 protein, human (EC 3.1.8.1)
Language	English
Publishing date	2023-10-05
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	218799-1
ISSN	1872-7786 ; 0009-2797
ISSN (online)	1872-7786
ISSN	0009-2797
DOI	10.1016/j.cbi.2023.110749
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Zs.A 686: Show issues

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Article: Carotenoid Composition of

Varga, Erzsébet / Balázs, Viktória Lilla / Sándor, Viktor / Agócs, Attila / Nagy, Veronika / Király, Sándor Balázs / Kurtán, Tibor / Molnár, Péter / Deli, József

Plants (Basel, Switzerland)

2023 Volume 12, Issue 24

Abstract: The carotenoid composition of the flower ... ...

Abstract	The carotenoid composition of the flower of
Language	English
Publishing date	2023-12-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants12244116
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Article ; Online: New

Varga, Petra Regina / Karaghiosoff, Konstantin / Sári, Éva Viktória / Simon, András / Hegedűs, László / Drahos, László / Keglevich, György

Organic & biomolecular chemistry

2023 Volume 21, Issue 8, Page(s) 1709–1718

Abstract: Diethyl α-benzylamino- and α-amino-benzylphosphonates obtained by the Kabachnik-Fields reaction were useful intermediates in the synthesis of other derivatives. Acylation of α-aminophosphonates with acyl chlorides led to the ... ...

Abstract	Diethyl α-benzylamino- and α-amino-benzylphosphonates obtained by the Kabachnik-Fields reaction were useful intermediates in the synthesis of other derivatives. Acylation of α-aminophosphonates with acyl chlorides led to the corresponding
Language	English
Publishing date	2023-02-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2097583-1
ISSN	1477-0539 ; 1477-0520
ISSN (online)	1477-0539
ISSN	1477-0520
DOI	10.1039/d3ob00010a
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Article: Radiation of mushroom-forming fungi correlates with novel modes of protecting sexual fruiting bodies

Varga, Torda / Földi, Csenge / Bense, Viktória / Nagy, László G.

Fungal biology. 2022 July 10,

2022

Abstract	The protection of vulnerable developing structures evolved repeatedly in terrestrial organisms and includes, among others, viviparity in animals and the seed in land plants. In mushroom-forming fungi (Agaricomycetes), sexual spores are born on fruiting bodies, the growth of which is a complex developmental process that is exposed to environmental factors (e.g., desiccation, fungivorous animals). Mushroom-forming fungi evolved a series of innovations in fruiting body protection, however, how these emerged is obscure, leaving the evolutionary principles of fruiting body development poorly known. Here, we show that developmental innovations that lead to the spore-producing surface (hymenophore) being enclosed in a protected environment display asymmetry in their evolution and are associated with increased diversification rates. ‘Enclosed’ development evolved convergently and became a dominant developmental type in several clades of mushrooms. This probably mirrors spore production benefits for species with protected fruiting body initials, by better coping with environmental factors. Our observations highlight new morphological traits associated with mushroom diversification that parallel the evolution of protection strategies in other organisms, such as viviparity or the seed in animals or plants, respectively, but in the context of spore development, highlighting the general importance of protecting vulnerable progeny across the tree of life.
Keywords	Agaricomycetes ; asymmetry ; evolution ; fungivores ; mushrooms ; mycology ; progeny ; spores
Language	English
Dates of publication	2022-0710
Publishing place	Elsevier Ltd
Document type	Article
Note	Pre-press version
ZDB-ID	2532164-X
ISSN	1878-6162 ; 1878-6146
ISSN (online)	1878-6162
ISSN	1878-6146
DOI	10.1016/j.funbio.2022.07.001
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Inhaled H 2 or CO 2 Do Not Augment the Neuroprotective Effect of Therapeutic Hypothermia in a Severe Neonatal Hypoxic-Ischemic Encephalopathy Piglet Model

Viktória Kovács / Gábor Remzső / Valéria Tóth-Szűki / Viktória Varga / János Németh / Ferenc Domoki

International Journal of Molecular Sciences, Vol 21, Iss 6801, p

2020 Volume 6801

Abstract: Hypoxic-ischemic encephalopathy (HIE) is still a major cause of neonatal death and disability as therapeutic hypothermia (TH) alone cannot afford sufficient neuroprotection. The present study investigated whether ventilation with molecular hydrogen (2.1% ...

Abstract	Hypoxic-ischemic encephalopathy (HIE) is still a major cause of neonatal death and disability as therapeutic hypothermia (TH) alone cannot afford sufficient neuroprotection. The present study investigated whether ventilation with molecular hydrogen (2.1% H 2 ) or graded restoration of normocapnia with CO 2 for 4 h after asphyxia would augment the neuroprotective effect of TH in a subacute (48 h) HIE piglet model. Piglets were randomized to untreated naïve, control‑normothermia, asphyxia‑normothermia (20-min 4%O 2 –20%CO 2 ventilation; T core = 38.5 °C), asphyxia‑hypothermia (A-HT, T core = 33.5 °C, 2–36 h post‑asphyxia), A-HT + H 2 , or A-HT + CO 2 treatment groups. Asphyxia elicited severe hypoxia (pO 2 = 19 ± 5 mmHg) and mixed acidosis (pH = 6.79 ± 0.10). HIE development was confirmed by altered cerebral electrical activity and neuropathology. TH was significantly neuroprotective in the caudate nucleus but demonstrated virtually no such effect in the hippocampus. The mRNA levels of apoptosis-inducing factor and caspase-3 showed a ~10-fold increase in the A-HT group compared to naïve animals in the hippocampus but not in the caudate nucleus coinciding with the region-specific neuroprotective effect of TH. H 2 or CO 2 did not augment TH‑induced neuroprotection in any brain areas; rather, CO 2 even abolished the neuroprotective effect of TH in the caudate nucleus. In conclusion, the present findings do not support the use of these medical gases to supplement TH in HIE management.
Keywords	hypoxic-ischemic encephalopathy ; perinatal asphyxia ; therapeutic hypothermia ; piglet model ; hydrogen ventilation ; brain-derived neurotrophic factor ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	290
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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