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  1. Article ; Online: Special Issue "Hepatitis B Virus: New Breakthroughs to Conquer an Ancient Disease".

    Tu, Thomas / Douglas, Mark W

    Viruses

    2023  Volume 15, Issue 11

    Abstract: Chronic hepatitis B affects >300 million people worldwide and is a major cause of liver disease, causing ~800,000 deaths each year [ ... ]. ...

    Abstract Chronic hepatitis B affects >300 million people worldwide and is a major cause of liver disease, causing ~800,000 deaths each year [...].
    MeSH term(s) Humans ; Hepatitis B virus/genetics ; Hepatitis B, Chronic ; Hepatitis B
    Language English
    Publishing date 2023-10-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15112173
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  2. Article ; Online: Guidelines for Performing Disability Evaluations.

    Hyman, Mark H / Martin, Douglas W

    American family physician

    2023  Volume 108, Issue 5, Page(s) Online

    MeSH term(s) Humans ; Disability Evaluation ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 412694-4
    ISSN 1532-0650 ; 0002-838X ; 0572-3612
    ISSN (online) 1532-0650
    ISSN 0002-838X ; 0572-3612
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Targeting liver metabolism: a pathway to cure hepatitis B virus?

    Ajoyan, Harout / Douglas, Mark W / Tu, Thomas

    Expert review of gastroenterology & hepatology

    2023  Volume 17, Issue 7, Page(s) 645–647

    MeSH term(s) Humans ; Hepatitis B virus/genetics ; Hepatitis B, Chronic/drug therapy ; Antiviral Agents/therapeutic use ; Hepatitis B Surface Antigens ; Hepatitis B/diagnosis ; Hepatitis B/drug therapy ; DNA, Viral
    Chemical Substances Antiviral Agents ; Hepatitis B Surface Antigens ; DNA, Viral
    Language English
    Publishing date 2023-06-18
    Publishing country England
    Document type Editorial
    ZDB-ID 2481021-6
    ISSN 1747-4132 ; 1747-4124
    ISSN (online) 1747-4132
    ISSN 1747-4124
    DOI 10.1080/17474124.2023.2226390
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  4. Article ; Online: Hepatitis B Virus Infection: From Diagnostics to Treatments.

    Tu, Thomas / Douglas, Mark W

    Viruses

    2020  Volume 12, Issue 12

    Abstract: In this Special Issue, we have brought together a broad range of studies on hepatitis B virus (HBV) covering diagnosis, pathogenesis, monitoring, and treatment [ ... ]. ...

    Abstract In this Special Issue, we have brought together a broad range of studies on hepatitis B virus (HBV) covering diagnosis, pathogenesis, monitoring, and treatment [...].
    MeSH term(s) Disease Management ; Disease Susceptibility ; Hepatitis B/diagnosis ; Hepatitis B/therapy ; Hepatitis B/virology ; Hepatitis B virus/physiology ; Humans
    Language English
    Publishing date 2020-11-30
    Publishing country Switzerland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v12121366
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  5. Book ; Online ; E-Book: Clinical genomics : practical applications in adult patient care

    Murray, Michael F. / Babyatsky, Mark W. / Stewart, Douglas R. / Murray, Michael F / Alkuraya, Fowzan S. / Giovanni, Monica A.

    2014  

    Abstract: Convert the latest genomic data to the most effective patient management and treatment approaches Clinical Genomics helps healthcare providers translate the vast amount of new genomic data into successful clinical application. It is a comprehensive ... ...

    Abstract Convert the latest genomic data to the most effective patient management and treatment approaches Clinical Genomics helps healthcare providers translate the vast amount of new genomic data into successful clinical application. It is a comprehensive textbook and practical guide to the use of this information across a broad spectrum of adult diseases - from individual differences in drug responses, cardiac and cancer risks to Alzheimer's and other neurological and psychiatric disorders. While traditional textbooks on medical genetics focus on classic Mendelian disorders, Clinical Genomics discusses the everyday application of genetic assessment and the diagnostic, therapeutic, and preventive implications to the most common adult diseases that healthcare providers encounter. Covering approximately 200 conditions, it is a true clinical text for use across all of internal medicine. Coverage of each condition is presented in a consistent, clinically relevant manner and includes: Key PointsDiagnostic Criteria and Clinical CharacteristicsScreening and C ounselingManagement and TreatmentMolecular Genetics and Molecular MechanismSupplementary Information More than ten valuable appendices, include Genetic Privacy; Race, Ancestry, and Genetics; Personalized Medicine in Clinical Practice; Clinical Interpretation of Genomic Data; and Genetic Risk Profiling in the Genomics Era. Clinical Genomics is essential for internists, primary care physicians, and other healthcare providers who wish to increase their knowledge of the gene-and-protein level care of patients in a clinical setting.
    MeSH term(s) Genetics ; Computational Biology ; Medicine ; Health Occupations ; Biology ; Biological Science Disciplines ; Disciplines and Occupations ; Natural Science Disciplines ; Clinical Medicine ; Genomics
    Keywords Genomics ; Medical genetics ; Biology ; Health & Biological Sciences ; Genetics
    Subject code 572.8/6
    Language English
    Size 1 online resource (959 pages)
    Edition 1st ed.
    Publisher McGraw Hill
    Publishing place New York
    Document type Book ; Online ; E-Book
    Note English ; Bibliographic Level Mode of Issuance: Monograph
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-07-162244-6 ; 978-0-07-162244-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Structural Inequities, HIV Community-Based Organizations, and the End of the HIV Epidemic.

    Robillard, Alyssa G / Julious, Carmen H / Smallwood, Stacy W / Douglas, Mark / Gaddist, Bambi W / Singleton, Tyler

    American journal of public health

    2022  Volume 112, Issue 3, Page(s) 417–425

    Abstract: Community-based organizations (CBOs) are integral to achieving the goal of Ending the HIV epidemic (EHE). Their familiarity with and proximity to communities position them to effectively implement strategies necessary to address determinants of health ... ...

    Abstract Community-based organizations (CBOs) are integral to achieving the goal of Ending the HIV epidemic (EHE). Their familiarity with and proximity to communities position them to effectively implement strategies necessary to address determinants of health through their formal and informal medical and social services. However, structural inequities have contributed to the demise of many organizations that were instrumental in early responses to the HIV epidemic. We define structural inequities for HIV CBOs as systems in which policies, institutional practices, organizational (mis)representations, and other norms work to produce and maintain inequities that affect CBOs' ability to survive and thrive. In this discussion, we describe the organizational threats to grassroots HIV CBOs and the risks to livelihood and longevity, including examples. The invaluable role of HIV CBOs in EHE and their role in responding to existing and novel infectious diseases like COVID-19 should not be overlooked. Recommendations to promote structural equity are offered. (
    MeSH term(s) Community Networks/organization & administration ; Epidemics ; HIV Infections/epidemiology ; Humans ; Organizations, Nonprofit/economics ; Organizations, Nonprofit/organization & administration
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2021.306688
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  7. Article ; Online: Polo-like kinase-1 mediates hepatitis C virus-induced cell migration, a drug target for liver cancer.

    El-Khobar, Korri E / Tay, Enoch / Diefenbach, Eve / Gloss, Brian S / George, Jacob / Douglas, Mark W

    Life science alliance

    2023  Volume 6, Issue 11

    Abstract: Polo-like kinase 1 (PLK1) is a regulator of cell mitosis and cytoskeletal dynamics. ...

    Abstract Polo-like kinase 1 (PLK1) is a regulator of cell mitosis and cytoskeletal dynamics.
    MeSH term(s) Humans ; Hepacivirus ; Actins ; Carcinoma, Hepatocellular/genetics ; Liver Neoplasms/genetics ; Hepatitis C ; Cell Movement/genetics ; Polo-Like Kinase 1
    Chemical Substances Actins
    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2575-1077
    ISSN (online) 2575-1077
    DOI 10.26508/lsa.202201630
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  8. Article ; Online: The Activity Management Inventory for Pain (AMI-P): Initial Development and Validation of a Questionnaire Based on Operant Learning and Energy Conservation Models of Activity Management.

    Racine, Mélanie / Jensen, Mark P / Cane, Douglas / Moulin, Dwight E / Vlaeyen, Johan W S / Nielson, Warren R

    The Clinical journal of pain

    2024  Volume 40, Issue 4, Page(s) 200–211

    Abstract: Objectives: Activity management is an important treatment component in chronic pain programs. However, there are shortcomings in measures of this construct, leading to inconsistencies in research findings. Here, we describe the development of the ... ...

    Abstract Objectives: Activity management is an important treatment component in chronic pain programs. However, there are shortcomings in measures of this construct, leading to inconsistencies in research findings. Here, we describe the development of the Activity Management Inventory for Pain (AMI-P).
    Materials and methods: The AMI-P was developed by a group of international researchers with extensive expertise in both chronic pain and activity management. The initial evaluation of the AMI-P items included 2 studies that were both conducted in Canadian tertiary pain care centers.
    Results: The resulting 20-item measure has 3 behavior scales (Rest, Alternating Activity, and Planned Activity), and 4 goal scales (Feel Less Pain, Get More Done, Complete the Task, and Save Energy). The behavior scales evidenced marginal to good internal consistency and test-retest reliability, and a moderate positive association with an existing pacing measure. The Rest and Alternating Activity scales were associated with greater pain interference, the Alternating Activity and Planned Activity scales were associated with less satisfaction with social roles, and the Planned Activity scale was associated with fewer depressive symptoms. The Alternating Activity scale increased significantly from pretreatment to posttreatment. All goal scales were positively associated with all behavior scales. The Feel Less Pain goal scale was positively associated with measures of avoidance and pain interference, while the Get More Done goal scale was negatively associated with measures of depressive symptoms and overdoing.
    Discussion: The findings support the reliability and validity of the AMI-P scales, while also highlighting the complexity and multidimensional aspects of activity management.
    MeSH term(s) Humans ; Chronic Pain/diagnosis ; Chronic Pain/therapy ; Reproducibility of Results ; Canada ; Pain Management ; Surveys and Questionnaires ; Psychometrics
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632582-8
    ISSN 1536-5409 ; 0749-8047
    ISSN (online) 1536-5409
    ISSN 0749-8047
    DOI 10.1097/AJP.0000000000001198
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    In stock of ZB MED Cologne/Königswinter

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  9. Article: Transmission of Eimeria, Viruses, and Bacteria to Chicks: Darkling Beetles (Alphitobius diaperinus) as Vectors of Pathogens.

    Goodwin, Mark A / Waltman, W Douglas

    The Journal of applied poultry research

    2019  Volume 5, Issue 1, Page(s) 51–55

    Abstract: Darkling beetle homogenates (DBH) were prepared from beetles collected from seven premises (farms). DBH were shown to contain myriad infectious organisms including bacteria ( ...

    Abstract Darkling beetle homogenates (DBH) were prepared from beetles collected from seven premises (farms). DBH were shown to contain myriad infectious organisms including bacteria (
    Keywords covid19
    Language English
    Publishing date 2019-12-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1193887-0
    ISSN 1537-0437 ; 1056-6171
    ISSN (online) 1537-0437
    ISSN 1056-6171
    DOI 10.1093/japr/5.1.51
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    In stock of ZB MED Bonn / Germany

    Z 5902: Show issues

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  10. Article ; Online: Carbon dioxide laser treatment of burn-related scarring: Results of the ELIPSE (Early Laser Intervention Promotes Scar Evolution) prospective randomized controlled trial.

    Lewis, Christopher J / Douglas, Helen / Martin, Lisa / Deng, Zhenjun / Melton, Phillip / Fear, Mark W / Wood, Fiona M / Rea, Suzanne

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 84, Page(s) 368–376

    Abstract: Aim: To investigate the impact of ablative fractional carbon dioxide laser (AFCO: Methods: Fifteen adult patients with a burn-related scar were recruited. Inclusion criteria were two non-contiguous scar areas of 1% total body surface area, similar ... ...

    Abstract Aim: To investigate the impact of ablative fractional carbon dioxide laser (AFCO
    Methods: Fifteen adult patients with a burn-related scar were recruited. Inclusion criteria were two non-contiguous scar areas of 1% total body surface area, similar baseline Vancouver scar scale (VSS) score and 3months since the time of injury. All participants acted as their own control. Scars were randomized to treatment or control. Treatment scars received three AFCO
    Results: No significant difference was found in VSS, scar erythema, or pigmentation. Patient POSAS improved in scar thickness and texture following AFCO
    Conclusions: AFCO
    MeSH term(s) Adult ; Humans ; Cicatrix/etiology ; Cicatrix/surgery ; Cicatrix/pathology ; Lasers, Gas/therapeutic use ; Treatment Outcome ; Prospective Studies ; Quality of Life ; Burns/complications ; Carbon Dioxide ; Cicatrix, Hypertrophic/pathology
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-06-19
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.06.012
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