LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 134

Search options

  1. Book ; Online ; E-Book: Mangroves

    Rastogi, Rajesh P. / Phulwaria, Mahendra / Gupta, Dharmendra K.

    ecology, biodiversity and management

    2021  

    Author's details Rajesh P. Rastogi, Mahendra Phulwaria, Dharmendra K. Gupta, editors
    Keywords Mangrove ecology ; Mangrove swamps ; Mangrove forests ; Manglars
    Subject code 574.526325
    Language English
    Size 1 online resource (551 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-2494-1 ; 981-16-2493-3 ; 978-981-16-2494-0 ; 978-981-16-2493-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Characterization, UV-induction, antioxidant function and role in photo-protection of mycosporine-like amino acids (MAAs) in a unicellular cyanobacterium, Euhalothece sp.WR7

    Rastogi, Rajesh P. / Shree, Anu / Patel, Hiral M. / Chaudhry, Smita / Madamwar, Datta

    Algal Research. 2023 Mar., v. 70 p.103030-

    2023  

    Abstract: Mycosporine-like amino acids (MAAs) are considered an important and unique UV-absorbing biomolecules. The present study was intended to explore the occurrence, UV-induction, free radical scavenging potential and photoprotective function of MAAs in the ... ...

    Abstract Mycosporine-like amino acids (MAAs) are considered an important and unique UV-absorbing biomolecules. The present study was intended to explore the occurrence, UV-induction, free radical scavenging potential and photoprotective function of MAAs in the cyanobacterium, Euhalothece sp.WR7. High-performance liquid chromatography (HPLC) coupled with photodiode-array (PDA) detection studies revealed the occurrence of two different UV-absorbing compounds having absorption maxima at 331 nm and 362 nm with retention time 6.4 and 10.2 min, respectively. Based on the HPLC-PDA detection and ion trap liquid chromatography-mass spectrometry (LC-MS) analysis, the compounds were identified as mycosporine-2-Glycine (M2G: λₘₐₓ 331 nm, m/z 303) and Euhalothece-362 (E-362: λmax 362 nm, m/z 331). Compared to the photosynthetically active radiation, a substantial induction of the synthesis of both MAAs was observed under UV (UV-A + UV-B) stress condition. MAAs (M2G + E-362) showed significant free radical scavenging potential in a dose-dependent manner. It also exhibited efficient photoprotective function by diminishing the UV-induced generation of reactive oxygen species (ROS) and enhancing the survival of Escherichia coli cells under UV-B stress. The results indicate the dynamic role of MAAs in existence and viability of cyanobacterium by regulating the key ecological functions in a harsh environment with intense solar UV irradiances. Moreover, MAAs may be used as important UV absorbers in cosmetic sunscreens due to their strong photoprotective function.
    Keywords Escherichia coli ; absorption ; algae ; antioxidant activity ; biochemical compounds ; dose response ; free radicals ; high performance liquid chromatography ; mass spectrometry ; photosynthetically active radiation ; radiation resistance ; reactive oxygen species ; research ; viability ; Cyanobacteria ; UV radiation ; Photoprotection ; Sunscreens ; Mycosporine ; Antioxidant
    Language English
    Dates of publication 2023-03
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ISSN 2211-9264
    DOI 10.1016/j.algal.2023.103030
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Serum Glutamic Oxaloacetic Transaminase - Predictor in Detection of Early Neurological Deterioration in Acute Ischemic Stroke.

    Gupta, Sudhish / Chetiwal, Rajesh / Kumar, Amit / Rastogi, Priyank / Gupta, Saurabh / Tomar, Pradeep

    The Journal of the Association of Physicians of India

    2022  Volume 70, Issue 4, Page(s) 11–12

    Abstract: ... neurological deterioration(p <0.01). END in stroke patients were found to have SGOT > 40 IU/ml (p= 0.05 ... Higher level of SGOT (>40 IU/m) l had association with NIHSS at admission (p =0.07), at 48 hours (p=0.04 ... and at 72 hours (p= 0.03) with mean of 9.66,10.45,11.45 respectively. Positive correlation had been ...

    Abstract In 20-40 percent of stroke patients, symptoms evolve during initial hours, resulting in rise of mortality. Early Neurological Deterioration (END) is now an emerging entity. In acute ischemic stroke, it results in increased mortality and functional disability. The incidence rates of early neurological deterioration is 13-37 percent of ischemic stroke. Ischemic stroke is associated with release of glutamate in brain. Serum glutamic oxaloacetic transaminase (SGOT) is the enzyme that metabolise glutamate and facilitates in lowering its level, but its significance is poorly understood. So, SGOT has been studied as predictor in detection of early neurological deterioration of acute ischemic stroke.
    Material: This was an observational prospective study in 100 in acute ischemic stroke patients with the age more than 18 years and presenting with in 24 hours after symptom onset. Detailed history of the patients was noted and detailed examination was carried out. National Institute of Health Stroke Scale (NIHSS) score was calculated at admission, at 24 hours and at 72 hours to see change in score and detect the early neurological deterioration. Early neurological deterioration was defined by change in the NIHSS Score of 2 or more than 2 with in 72 hours of stroke onset. SGOT level was sent within 24 hours of admission and studied as a contributing marker in detection of Early neurological deterioration.
    Observation: Among 100 patients enrolled in our study, there were more male patients (82%) with mean age of the 59.8 years. 72% of patients were diabetic and 84% were non alcoholic. Increase in SGOT value was found to be associated with early neurological deterioration(p <0.01). END in stroke patients were found to have SGOT > 40 IU/ml (p= 0.05). Higher level of SGOT (>40 IU/m) l had association with NIHSS at admission (p =0.07), at 48 hours (p=0.04) and at 72 hours (p= 0.03) with mean of 9.66,10.45,11.45 respectively. Positive correlation had been there between SGOT with NIHSS at admission, at 48 hours and at 72 hours .
    Conclusion: The increase in SGOT levels during stroke is associated with neurological deterioration. Hence, SGOT may be utilised as predictor in detection of END in acute ischemic stroke as high values of SGOT positively correlated with NIHSS at admission, at 48 hours and 72 hours.
    MeSH term(s) Adolescent ; Aspartate Aminotransferases ; Brain Ischemia/complications ; Brain Ischemia/diagnosis ; Female ; Glutamic Acid ; Humans ; Ischemic Stroke/complications ; Ischemic Stroke/diagnosis ; Male ; Middle Aged ; Prospective Studies ; Stroke/complications ; Stroke/diagnosis
    Chemical Substances Glutamic Acid (3KX376GY7L) ; Aspartate Aminotransferases (EC 2.6.1.1)
    Language English
    Publishing date 2022-04-17
    Publishing country India
    Document type Journal Article ; Observational Study
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 313: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Bacterial tolerance strategies against lead toxicity and their relevance in bioremediation application.

    Mitra, Anindita / Chatterjee, Soumya / Kataki, Sampriti / Rastogi, Rajesh P / Gupta, Dharmendra K

    Environmental science and pollution research international

    2021  Volume 28, Issue 12, Page(s) 14271–14284

    Abstract: Among heavy metals, lead (Pb) is a non-essential metal having a higher toxicity and without any crucial known biological functions. Being widespread, non-biodegradable and persistent in every sphere of soil, air and water, Pb is responsible for severe ... ...

    Abstract Among heavy metals, lead (Pb) is a non-essential metal having a higher toxicity and without any crucial known biological functions. Being widespread, non-biodegradable and persistent in every sphere of soil, air and water, Pb is responsible for severe health and environmental issues, which need appropriate remediation measures. However, microbes inhabiting Pb-contaminated area are found to have evolved distinctive mechanisms to successfully thrive in the Pb-contaminated environment without exhibiting any negative effects on their growth and metabolism. The defensive strategies used by bacteria to ameliorate the toxic effects of lead comprise biosorption, efflux, production of metal chelators like siderophores and metallothioneins and synthesis of exopolysaccharides, extracellular sequestration and intracellular bioaccumulation. Lead remediation technologies by employing microbes may appear as potential advantageous alternatives to the conventional physical and chemical means due to specificity, suitability for applying in situ condition and feasibility to upgrade by genetic engineering. Developing strategies by designing transgenic bacterial strain having specific metal binding properties and metal chelating proteins or higher metal adsorption ability and using bacterial activity such as incorporating plant growth-promoting rhizobacteria for improved Pb resistance, exopolysaccharide and siderophores and metallothionein-mediated immobilization may prove highly effective for formulating bioremediation vis-a-vis phytoremediation strategies.
    MeSH term(s) Bacteria ; Biodegradation, Environmental ; Lead/analysis ; Metals, Heavy/analysis ; Soil Pollutants/analysis
    Chemical Substances Metals, Heavy ; Soil Pollutants ; Lead (2P299V784P)
    Language English
    Publishing date 2021-02-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-12583-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Therapeutic potential of bioactive compounds from Punica granatum extracts against aging and complicity of FOXO orthologue DAF-16 in

    Chaubey, Mukesh G / Chauhan, Anita P / Chokshi, Pooja R / Amin, Rahi S / Patel, Stuti N / Madamwar, Datta / Rastogi, Rajesh P / Singh, Niraj Kumar

    EXCLI journal

    2021  Volume 20, Page(s) 80–98

    Abstract: Some natural fruits have significant importance in improving health which provides many nutritional supplements essential to maintain proper metabolism with the age. In this study, phytochemical screening of extract (methanolic) ... ...

    Abstract Some natural fruits have significant importance in improving health which provides many nutritional supplements essential to maintain proper metabolism with the age. In this study, phytochemical screening of extract (methanolic) of
    Language English
    Publishing date 2021-01-11
    Publishing country Germany
    Document type Journal Article
    ISSN 1611-2156
    ISSN 1611-2156
    DOI 10.17179/excli2020-3011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Cyanobacterial diversity in mat sample obtained from hypersaline desert, Rann of Kachchh.

    Patel, Hiral M / Rastogi, Rajesh P / Trivedi, Ujjval / Madamwar, Datta

    3 Biotech

    2019  Volume 9, Issue 8, Page(s) 304

    Abstract: Rann of Kachchh (RoK) is a unique geoformation, which is exposed to dynamic environmental changes such as salinity, temperature, and nutrients throughout the year. In this study, the pooled mat sample was examined for the cyanobacterial community ... ...

    Abstract Rann of Kachchh (RoK) is a unique geoformation, which is exposed to dynamic environmental changes such as salinity, temperature, and nutrients throughout the year. In this study, the pooled mat sample was examined for the cyanobacterial community structure using culture-dependent and culture-independent approaches. Taxonomic profiling was studied using amplicon sequencing that revealed the enrichment of Pseudanabaenales and Oscillatoriales by QIIME and MG-RAST, respectively. Other abundant orders were represented by Chroococcales, Nostocales, and unclassified cyanobacteria by both approaches. Nine cyanobacterial cultures were isolated from mat samples showing 90-98% similarities with available sequences in GenBank. The culture-dependent study suggested that mat was dominated by cyanobacterial orders such as Oscillatoriales-filamentous and Chroococcales-unicellular. Our results from the culture-dependent approach also indicated that despite high similarities in gene sequences, six cyanobacteria fall into the separate clade in the phylogenetic analysis that could be signs of evolution due to an extreme environment. Cultured isolates are correlated well with abundant taxa from amplicon sequencing. Further, protein profiling was done specifically for phycobiliproteins which will be helpful to elucidate their roles in light harvesting and energy transfer mechanism in the unique environment of RoK.
    Language English
    Publishing date 2019-07-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-019-1837-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Bioprospecting of fucoxanthin from diatoms — Challenges and perspectives

    Seth, Kunal / Kumar, Ashwani / Rastogi, Rajesh P. / Meena, Mukesh / Vinayak, Vandana / Harish

    Algal research. 2021 Dec., v. 60

    2021  

    Abstract: Diatoms are ubiquitous microalgae that exhibit a characteristic golden-brown color due to the high quantity of fucoxanthin. Fucoxanthin is a brown pigment molecule that belongs to the xanthophyll class of carotenoids. Owing to unique chemical properties, ...

    Abstract Diatoms are ubiquitous microalgae that exhibit a characteristic golden-brown color due to the high quantity of fucoxanthin. Fucoxanthin is a brown pigment molecule that belongs to the xanthophyll class of carotenoids. Owing to unique chemical properties, this pigment is known for a variety of biological functions having important medicinal properties like anti-inflammatory, anti-oxidant, anti-obesity, anti-diabetic, anti-cancer, anti-osteoporotic, anti-hypertensive, and anti-microbial activities. On account of its versatile applications and growing demands, it is one of the exorbitant pigments globally and plays a crucial role in the circular bioeconomy. Extraction of fucoxanthin from a natural source is considered most efficient, eco-friendly, and cost-effective. Therefore, selecting a suitable natural source for efficient extraction, quantification, purification of this economically important biomolecule is of utmost importance. This paper presents the current understanding of the fucoxanthin biosynthetic pathway in diatoms, characterizations of essential genes involved in its biosynthesis, and various efforts to enhance production using the biorefinery approach reviewed. This review also focuses on current knowledge of extraction methods and biological functions of fucoxanthin with its potential health benefits.
    Keywords antioxidants ; biochemical pathways ; bioeconomics ; biorefining ; biosynthesis ; color ; cost effectiveness ; lutein ; microalgae ; research
    Language English
    Dates of publication 2021-12
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 2211-9264
    DOI 10.1016/j.algal.2021.102475
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Characterization of UV-screening compounds, mycosporine-like amino acids, and scytonemin in the cyanobacterium Lyngbya sp. CU2555.

    Rastogi, Rajesh P / Incharoensakdi, Aran

    FEMS microbiology ecology

    2014  Volume 87, Issue 1, Page(s) 244–256

    Abstract: Ultraviolet-screening compounds from the cyanobacterium Lyngbya sp. CU2555 were partially characterized and investigated for their induction by UV radiation, stability under different abiotic factors, and free radical scavenging activity. Based on the ... ...

    Abstract Ultraviolet-screening compounds from the cyanobacterium Lyngbya sp. CU2555 were partially characterized and investigated for their induction by UV radiation, stability under different abiotic factors, and free radical scavenging activity. Based on the high-performance liquid chromatography coupled with diode array detector and ion trap liquid chromatography/mass spectrometry analysis, the compounds were identified as palythine (UVλ max: 319 nm; m/z: 245), asterina (UVλ max: 330 nm; m/z: 289), scytonemin (UVλ max: 384 nm; mw: 544), and reduced scytonemin (UVλ max: 384 nm; m/z: 547). This is the first report for the occurrence of palythine, asterina, and an unknown mycosporine-like amino acids (MAA), M-312 (UVλ max: 312 ± 1 nm), in addition to scytonemin and reduced scytonemin in Lyngbya strains studied so far. Induction of MAAs and scytonemin was significantly more prominent upon exposure to UV-A + UV-B radiation. Both MAAs and scytonemin were highly resistant to some physicochemical factors such as UV-B, heat, and a strong oxidizing agent and exhibited strong antioxidant activity. These results indicate that the studied cyanobacterium may protect itself from deleterious short-wavelength radiation by synthesizing photoprotective compounds in response to harmful UV radiation.
    MeSH term(s) Amino Acids/analysis ; Amino Acids/biosynthesis ; Chromatography, High Pressure Liquid ; Cyanobacteria/chemistry ; Cyanobacteria/metabolism ; Cyanobacteria/radiation effects ; Cyclohexanols/analysis ; Cyclohexanols/metabolism ; Glycine/analogs & derivatives ; Glycine/analysis ; Glycine/metabolism ; Indoles/analysis ; Indoles/metabolism ; Phenols/analysis ; Phenols/metabolism ; Ultraviolet Rays
    Chemical Substances Amino Acids ; Cyclohexanols ; Indoles ; Phenols ; palythine ; scytonemin (152075-98-4) ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2014-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 283722-5
    ISSN 1574-6941 ; 0168-6496
    ISSN (online) 1574-6941
    ISSN 0168-6496
    DOI 10.1111/1574-6941.12220
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2967: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: UV radiation-induced biosynthesis, stability and antioxidant activity of mycosporine-like amino acids (MAAs) in a unicellular cyanobacterium Gloeocapsa sp. CU2556.

    Rastogi, Rajesh P / Incharoensakdi, Aran

    Journal of photochemistry and photobiology. B, Biology

    2014  Volume 130, Page(s) 287–292

    Abstract: The biosynthesis of natural sunscreening compounds as influenced by ultraviolet radiation, their stability and antioxidant activity were studied in the cyanobacterium Gloeocapsa sp. CU-2556. An analysis by high-performance liquid chromatography (HPLC) ... ...

    Abstract The biosynthesis of natural sunscreening compounds as influenced by ultraviolet radiation, their stability and antioxidant activity were studied in the cyanobacterium Gloeocapsa sp. CU-2556. An analysis by high-performance liquid chromatography (HPLC) with photodiode-array (PDA) detection revealed the biosynthesis of two MAAs, shinorine (UVλmax 333nm) and an unknown MAA designated as M-307 (UVλmax 307nm) with retention times of 5.9 and 6.4min, respectively. Induction of the synthesis of MAAs was studied under 395 (PAR), 320 (PAR+UV-A) and 295 (PAR+UV-A+UV-B) nm cut-off filters. MAAs induction was significantly increased with an increase in exposure time up to 72h in the samples covered with 295nm cut-off filters. Contrary to shinorine, the biosynthesis of M-307 was more dominant in this unicellular cyanobacterium. Both MAAs were highly stable to some physico-chemical stressors such as UV radiation, heat and a strong oxidizing agent. The MAA M-307 was more stable under strong oxidative stress than shinorine. Moreover, UV-C radiation drastically decreased the stability of both MAAs. The MAAs (shinorine+M-307) also exhibited efficient antioxidant activity which was dose-dependent. The results indicate that MAAs may perform a vital role in survival and sustainability of Gloeocapsa sp. CU-2556 in harsh environmental conditions by its ability to absorb/screen short wavelength UV radiation and antioxidant function.
    MeSH term(s) Amino Acids/isolation & purification ; Amino Acids/metabolism ; Amino Acids/pharmacology ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Cyanobacteria/metabolism ; Cyanobacteria/radiation effects ; Ultraviolet Rays
    Chemical Substances Amino Acids ; Antioxidants
    Language English
    Publishing date 2014-01-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 623022-2
    ISSN 1873-2682 ; 1011-1344
    ISSN (online) 1873-2682
    ISSN 1011-1344
    DOI 10.1016/j.jphotobiol.2013.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2347: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Analysis of UV-absorbing photoprotectant mycosporine-like amino acid (MAA) in the cyanobacterium Arthrospira sp. CU2556.

    Rastogi, Rajesh P / Incharoensakdi, Aran

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2014  Volume 13, Issue 7, Page(s) 1016–1024

    Abstract: Mycosporine-like amino acids (MAAs) are ecologically important biomolecules with great photoprotective potential. The present study aimed to investigate the biosynthesis of MAAs in the cyanobacterium Arthrospira sp. CU2556. High-performance liquid ... ...

    Abstract Mycosporine-like amino acids (MAAs) are ecologically important biomolecules with great photoprotective potential. The present study aimed to investigate the biosynthesis of MAAs in the cyanobacterium Arthrospira sp. CU2556. High-performance liquid chromatography (HPLC) with photodiode-array detection studies revealed the presence of a UV-absorbing compound with an absorption maximum at 310 nm. Based on its UV absorption spectrum and ion trap liquid chromatography/mass spectrometry (LC/MS) analysis, the compound was identified as a primary MAA mycosporine-glycine (m/z: 246). To the best of our knowledge this is the first report on the occurrence of MAA mycosporine-glycine (M-Gly) in Arthrospira strains studied so far. In contrast to photosynthetic activity under UV-A radiation, the induction of the biosynthesis of M-Gly was significantly more prominent under UV-B radiation. The content of M-Gly was found to increase with the increase in exposure time under UV-B radiation. The MAA M-Gly was highly stable under UV radiation, heat, strongly acidic and alkaline conditions. It also exhibited good antioxidant activity and photoprotective ability by detoxifying the in vivo reactive oxygen species (ROS) generated by UV radiation. Our results indicate that the studied cyanobacterium may protect itself by synthesizing the UV-absorbing/screening compounds as important defense mechanisms, in their natural brightly-lit habitat with high solar UV-B fluxes.
    MeSH term(s) Amino Acids/chemistry ; Antioxidants/chemistry ; Antioxidants/metabolism ; Chromatography, High Pressure Liquid ; Cyanobacteria/metabolism ; Cyclohexanones/analysis ; Cyclohexanones/metabolism ; Glycine/analogs & derivatives ; Glycine/analysis ; Glycine/biosynthesis ; Photosynthesis/radiation effects ; Radiation-Protective Agents/analysis ; Radiation-Protective Agents/metabolism ; Reactive Oxygen Species/metabolism ; Ultraviolet Rays
    Chemical Substances Amino Acids ; Antioxidants ; Cyclohexanones ; Radiation-Protective Agents ; Reactive Oxygen Species ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2014-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1039/c4pp00013g
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top